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워시드 커피와 내추럴 커피를 활용한 커피제조 과정에서의 항산화 성분 분석
신혜경,Shin, Hye-Kyung 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.4
This study examines the changes in chlorogenic acid (CGA), an antioxidant, and one of its decomposition substances, caffeic acid, at various roasting stages and extraction conditions. Based on the CGA content for each roasting stage, at $3^{\circ}C$ after the beginning of the $1^{st}$ crack, the CGA decreased for washed beans and natural beans by more than 50% compared to that of green coffees. The CGA continued to decrease sharply by more than 75% at the end of the $1^{st}$ crack for washed beans and at $5^{\circ}C$ after the end of the $1^{st}$ crack for natural beans. At the peak of the $2^{nd}$ crack, it had decreased by more than 90% for both beans. The Caffeic acid content gradually increased for both washed and natural beans, then rapidly increased from the beginning of the $2^{nd}$ crack to the peak of the $2^{nd}$ crack. However, its contents were very small in quantity. Additionally, the content of CGAs for differing extraction conditions were in the order of 3-CGA, Crypto-CGA, and Neo-CGA. Crypto-CGA content was about half that of 3-CGA and Neo-CGA content was approximately 100 ppm less than that of Crypto-CGA. This study was conducted in order to help make coffee that has the most antioxidant effect.
어린이병원 신규간호사를 위한 간호역량 향상 교육프로그램개발 및 효과검증
신혜경,김효영,김현정,김민경,신현주,이후연,한지희,이혜정 한국간호교육학회 2022 한국간호교육학회지 Vol.28 No.2
Purpose: The purpose of this study is to identify the effects of a standardized educational program to improve nursing competency on newly graduated nurses in a children's hospital after developing and applying a pediatric nurse education program. The effectiveness of the program was confirmed by evaluating the clinical competency and field adaptation. Methods: In the first step, an education program was developed using the analysis, design, development, implementation and evaluation (ADDIE) model. As a second step, a similar experimental study of a single group repeat measures design was conducted to evaluate the clinical competency and field adaptation over time after application of the program. Additionally, a focus group interviews were conducted to collect subjective data on the effects and improvement points of the program. Results: As a result of applying the program, there was a significant change in the clinical competence and the field adaptation of newly graduated nurses in a children’s hospital. The categories derived from the focus group interviews were “getting special guidance,” “better care,” “becoming a nurse at a children's hospital” and “winning together.” Conclusion: It was confirmed that the education program enhances the clinical competency of new nurses in children's hospitals. In addition, it provided the necessary data to understand the experiences of new nurses, help them adapt effectively, and establish appropriate interventions.
Antimicrobial characteristics of N-halaminated chitosan salt/cotton knit composites
신혜경,김학용,박수진,박미라,정용식,Fan-Long Jin 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4
Chlorinated chitosan salt/cotton knit composites were prepared, and their water absorbencies, physical and antimicrobial properties, and rechargeabilities were investigated. The water absorbencies of the composites dissolved in acetic acid were higher than in hydrochloric acid. The tensile stress and strain of the composites decreased with increasing citric acid content. The active-chlorine contents of the composites increased with both increasing chlorination time and increasing concentration of the chlorination solution. Antimicrobial tests indicated that the composites had high antimicrobial activity: they completely eliminated Esherichia coli and Staphylococcus aureus. After rechlorination, the active-chlorine content of the composite was slightly higher than that after the initial chlorination, which indicates that the chitosan salt/cotton knit composites are highly rechargeable.
신혜경,박미라,강필현,최흥섭,박수진 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5
This study evaluated the feasibility of polyacrylonitrile (PAN) fibers stabilized by thermal treatment after electron beam irradiation (EBI) in the production of carbon fibers. The effects of EBI and thermal treatments on the PAN precursor were verified by FT-IR, differential scanning calorimetry (DSC), X-ray diffraction (XRD), and scanning electron microscopy (SEM). FT-IR spectra confirmed that the intensities of the CBBN stretching vibration at 2244 cm 1 significantly decreased as the thermal treatment temperature increase from 200 ℃ to 250 ℃ and the holding time from 20 min to 40 min after EBI process. This decrease was caused by the cyclization of nitrile groups upon stabilization by the EBI and thermal treatments. The thermal properties were characterized by DSC, which confirmed that the EBI affected the quantity of the released heat as well as the position of exothermic equilibrium over a wide range of low temperatures. The majority of the exothermic peaks disappeared after thermal treatment. The stabilization index (SI) values for the PAN fibers that were exposed to EBI and thermal treatment after EBI were evaluated by XRD. The SI value of the PAN fibers that were treated at 250 ℃ for 40 min after EBI was 99.21%. Additionally, the tensile strength of carbon fibers that were produced from PAN attained about 2.3 GPa, the cross-section exhibited a clear and brittle morphology.
신혜경,박수진,박미라,김학용 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.32 No.-
This work evaluated the effect of various amounts of tension on polyacrylonitrile (PAN) precursor fibersduring electron beam irradiation (EBI) stabilization. X-ray diffraction (XRD), tensile testing, and scanningelectron microscopy (SEM) were implemented to determine the effects of tension on the PAN fibers. During the stabilization process, the fibers shrunk due to a loss of molecular alignment, and the additionof tension acting on the PAN fibers during stabilization was proposed to address this issue. In this work,PAN fibers were stabilized by EBI under various loads. It was found from the XRD data that tension led tothe development of crystalline structures during EBI stabilization. From the tensile test, it was found thattension led to a small increase in strength due to conversion of disordered structures into orderedstructures in the fibers.
Bony Stability and Soft Tissue Changes after Orthognathic Surgery on Patients with Cleft
신혜경,조명수,Shin, Heakyeong,Hsieh, Yuh-Jia,Liao, Yu-Fang,Lo, Lun-Jou,Jo, Myoung-Soo Korean Cleft Palate-Craniofacial Association 2012 Archives of Craniofacial Surgery Vol.13 No.1
Purpose: The objective of this retrospective study was to assess the skeletal stability after orthognathic surgery for patients with cleft lip and palate. The soft tissue changes in relation to the skeletal movement were also evaluated. Methods: Thirty one patients with cleft received orthognathic surgery by one surgeon at the Craniofacial Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Osseous and soft tissue landmarks were localized on lateral cephalograms taken at preoperative (T0), postoperative (T1), and after completion of orthodontic treatment (T2) stages. Surgical movement (T0.T1) and relapse (T1.T2) were measured and compared. Results: Mean anteroposterior horizontal advancement of maxilla at point A was 5.5 mm, and the mean horizontal relapse was 0.5 mm (9.1%). The degree of horizontal relapse was found to be correlated to the extent of maxillary advancement. Mean vertical lengthening of maxilla at point A was 3.2 mm, and the mean vertical relapse was 0.6 mm (18.8%). All cases had maxillary clockwise rotation with a mean of 4.4 degrees. The ratio for horizontal advancement of nasal tip/anterior nasal spine was 0.54/1, and the ratio of A' point/A point was 0.68/1 and 0.69/1 for the upper vermilion/upper incisor tip. Conclusion: Satisfactory skeletal stability with an acceptable relapse rate was obtained from this study. High soft tissue to skeletal tissue ratios were obtained. Two-jaw surgery, clockwise rotation, rigid fixation, and alar cinch suture appeared to be the contributing factors for favorable results.
국소성 분절성 사구체 경화증(FSGS)을 동반한 Cockayne 증후군 1례
신혜경,김건하,임형은,홍영숙,이주원,원남희,유기환,Shin, Hye-Kyung,Kim, Gun-Ha,Yim, Hyung-Eun,Hong, Young-Sook,Lee, Joo-Won,Won, Nam-Hee,Yoo, Kee-Hwan 대한소아신장학회 2007 Childhood kidney diseases Vol.11 No.1
Cockayne syndrome is a rare autosomal recessive disorder characterized by cachectic dwafism, mental retardation, loss of facial subcutaneous adipose tissue, microcephaly and photosensitive dermatitis. It is associated with renal abnormalities characterized by hyalinization of glomeruli, atrophy of tubules and interstitial fibrosis. To our knowledge, this is the first report of a case of Cockayne syndrome with FSGS in Korea. A 7-year old boy was admitted for evaluation of hypertension and proteinuria, which were detected 2 month ago. He was followed for short stature(<3 percentile), mental retardation(IQ 55), strabismus and dental caries since 3 years ago. He also showed microcephaly, a bird-like face and relatively large hands and feet. Laboratory findings showed decreased creatinine clearance($C_{Cr}$ 76.1 mL/min/$1.73m^2$) and proteinuria(1,548 mg/day). Renal biopsy demonstrated focal segmental glomerulosclerosis of the hilar type with large hyaline deposits, moderate tubular atrophy and interstitial fibrosis. His cardinal features, mental retardation, and renal biopsy findings were consistent with Cockayne syndrome. We report here a very rare case of Cockayne syndrome with FSGS presenting with proteinuria and hypertension.