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본태성 고혈압 환자 적혈구막의 Na+ - Li+ Countertransport 에 관한 연구
신영우(Yung Uoo Shin),신영기(Yeong Kee Shin),손성표(Seong Puo Son),이동일(Dong Il Lee),김용근(Yong Kun Kim) 대한내과학회 1991 대한내과학회지 Vol.41 No.4
N/A In order to investigate the changes of Na+ transport system of the red blood cells in patients with essential hypertension, N+-Li+ countertransport was measured in 30 cases of essential hypertension and 20healthy normal controls. Furthermore, these measurements were analyzed in terms of some important clinical parameters in patients with essential hypertension, i.r., body mass index (BMI), status of hypertension, and plasma lipids. Na+-Li+ countertransport in the patient group significantly increased compared with the control group (62.2±4.5 and 46.8±3.0㎛ol/L cells.hr). In the analysis regarding the relationship between the Na+-Li+ countertransport system and some important clinical parameters of the patients with essential hypertension, Na+-Li+ countertransport was related to BMI, and the level of triglycerides did not show any significant relationship with the level of blood pressure, WHO class, and the level of cholesterol. These results suggest that Na+-Li+ countertransport systems in essential hypertensive patients were significantly altered compared with normal healthy controls but overlapped considerably between the 2groups.
이정유(Jung Yoo Lee),차광수(Kwang Su Cha),이종수(Jong Su Lee),김진도(Jin Do Kim),이형유(Hyung Yoo Lee),송철수(Chul Soo Song),신영우(Yung Uoo Shin),신영기(Yeong Kee Shin) 대한내과학회 1991 대한내과학회지 Vol.41 No.3
N/A The Authors investigated the serial change of serum lipids in the early period of acute myocardial infarction and its relation to several clinical parameters. The level of serum total cholesterol was lowest in the period of 2 to 5days after an attack of acute myocardial infarction, especially on the fourth day and thereafter increased gradually until 2 to 3weeks of the observation period. On the other hand the serum triglyceride level was lowest in the first 2days, especially the first day, and thereafter increased gradually until 2 to 3weeks of the observation period. The extent of the cholesterol change was very small compared with that of the triglyceride. The level of change in the serum cholesterol was not related to the ejection fraction, the frequency of ventricular arrhythmia, Killip class or fatality rate. On the otherhand the level of change in the serum triglyceride had a significant adverse influence on the ejection fraction, the frequency of ventricular arrhythmia, Killip class and fatality rate, respectively. Thus it seems that the initial change of serum triglyceride is somewhat helpful in foreseeing the outcome of acute myocardial infarction.