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정호현,이상미,이종철,박만용,김동웅,송봉권,김성철 대한침구의학회 2013 대한침구의학회지 Vol.25 No.4
Objectives : Weight loss and loss of appetite in amyotrophic lateral sclerosis patients arecommon symptoms, these are associated with survival as well as nutritional condition. Thechanges in weight and appetite were reported after treatment using Megestrol acetate andKorean medical treatments. Methods : Amyotrophic lateral sclerosis patient with weight loss and loss of appetite weretreated by administering megestrol acetate a known anti-malignant tumor agent and Koreanmedical treatments such as acupuncture, pharmacopuncture and herbal medicine. Thechanges in weight and appetite were checked using body mass index(BMI) and simplifiednutritional appetite questionnaire(SNAQ). Results : There was a more than 17 kg increase in weight. BMI increased from 15.94 kg/㎡ to21.97 kg/㎡ and SNAQ score increased from 7 to 16. Owing to several side effects, Megestrolacetate was stopped after which only Korean medical treatments were provided. After whichthe lasting effects in BMI and appetite could be seen. Conclusion : There are few studies on weight loss and loss of appetite in ALS patients. Usingonly megestrol acetate can cause several considerable side effects. Which respect to this, thefindings in this study could open up new clinical guideline possibilities.