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류마토이드 關節炎 患者 滑膜細胞에 대한 鷄血藤의 免疫反應
서해경,오민석,김동희 대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.3
This study was carried out to know the immunity responses of the Spatholubus suberectus Dunn(hereinafter referred to STSD) to the synovial cells isolated from patients with rheumatoid arthritis. Various experiments were performed in vitro to analyse the immunity effects of STSD. Gene expression and production of pro-inflammatory cytokines such as IL-1β, IL-6, TNF-α, iNOS and COX-2 were determined by RT-PCR and ELISA kit. And also the binding activity of NF-^kB and AP-1 were measured by Electromobility shift assay (EMSA) and the production of ROS was measured by flow cytometry. The results were obtained as follows 1. The gene expression and production of pro-inflammatory cytokines IL-1β, IL-6, TNF-α were reduced significantly. 2. The gene expression of iNOS and COX-2 were reduced. 3. The binding activity of NF-^kB and AP-1 were inhibited. 4. The production of ROS in human synovial cells was reduced significantly. Comparison of the results for this study showed that STSD had immunomodulatory effects of suppressing or enhancing. So we expect that STSD should be used as a effective drugs for not only rheumatoid arthritis but also another auto-immune disease. Therefore we have to survey continuously in looking for the effective substance and mechanism in the future.
徐海卿,吳旼錫,宋泰元 대전대학교 한의학연구소 2002 혜화의학회지 Vol.10 No.2
Objectives: There are a lot of food used herb medicine among the people in order to cure disease. A medicinal gruel is the easiest and most universal among alimmentotherapy. The purpose of this thesis is to understand a medicinal gruel therapy. Methods: I researched the definition, history, ingredients, application and special feature. Result and conclusion : A medicinal gruel therapy is alimmentotherapy for diseases prevent and diseases treatment which get mixed with her medicine and rice, based on oriental medicine theory. A medicinal gruel therapy was put on record in <A historical book>. A medicinal gruel therapy can be used in chronic diseases, convalescent stage, assistant treatment for acute disease, disease prevention, aging prevention, diet food and substitute food for breakfast.
허수영(Su-Young Heo),최진만(Jin-Man Choi),서해경(Hae-kyung Seo) 척추신경추나의학회 2001 대한추나의학회지 Vol.2 No.1
Objectives : Scalenus anticus syndrome and Piriformis syndrome is representative of myogenic Nerve entrapment syndrome, and their clinical symptoms are similar to HIVD(herniated intervertebral disc) of cervical or lumbar spine. But, distinguished by muscle test, these syndrome apply to Meridian-muscle therapy. Methods : Meridian-muscle therapy consists of Ashi(阿是)-point therapy, taping therapy, myofascial release technique, manipulation, their based on the traditional meridian-muscle theory. This theory is similar to myofascial pain syndrome in western medicine. The study population consisted of 9 patients who were already diagnosed as Nerve entrapment syndrome with radiological examination& physical examination and muscle test. The evaluation of clinical outcome was done by Visual Analogue Scale (VAS) and Pain Assesment Questionnaire(PAQ). Results and Conclusions : After treatment, All patient s VAS is decreased as 2.11±1.59 and the evaluation of clinical effect was excellent(6 cases) or good(3 cases) according to PAQ. Conclusively, Meridian muscle therapy is efficacious against Nerve entrapment syndrome.