A prediction model for cognitive decline in community-dwelling older people

백종환 ( Back Joung Hwan ) 대전대학교 기초과학연구소 2024 혜화보건의료학회지 Vol.3 No.1

Objectives: Because of rapid population aging, cognitive decline and dementia in the older population are recognized as major public health problems. The purpose of this study was to identify demographic, behavioral, medical, and genetic factors associated with cognitive decline, and to develop a model that can predict cognitive decline. Methods: Data for community-dwelling people aged 65 years and older were obtained from the Gyeonggi Dementia and Mild Cognitive Impairment Study (GDEMCIS). Cognitive decline was defined using the random slope and intercept linear mixed model. Those demonstrating a change in the slope of less than 0 were defined as decliners. Data mining such as decision tree and bagging methods were used to develop the prediction model for cognitive decline. Results: Among the subjects, 7.4% showed cognitive decline. Based on the area under the curve the prediction model based on decision tree analysis was selected. In the modeling dataset, 59 (7.4%) showed cognitive decline. The prediction model identified 49 cognitive decliners (6.2%). The correct classification rate of the prediction model was 93.4%. Conclusions: In this study, a prediction model for cognitive decline in community-dwelling older people was developed. The prediction model may provide useful information to healthcare professionals in identifying and monitoring older adults vulnerable to cognitive decline.

부모의 알레르기질환 과거력이 자녀의 아토피피부염에 미치는 영향

김영만 ( Young Man Kim ),김유찬 ( You Chan Kim ),이수진 ( Soojin Lee ),백종환 ( Joung Hwan Back ),전기홍 ( Kihong Chun ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.5

Purpose: This study aimed to examine the relationship between parent``s history of allergic disease and children``s atopic dermatitis. Methods: Data from the 2011 Research on the Current Status of Atopic Disease with Elementary Schools and Kindergartens in Suwon were used for analysis. Among 20,052 persons consenting to the survey, 18,943 who had answered parent``s history were included in the study. Results: The prevalence of father, mother, and parent``s allergic disease history were 8.5%, 9.5%, and 2.3%, respective. The children with atopic dermatitis comprised 15.1% of the study population. In multivariate analysis, gender, weight at birth, the practice of breast-feeding, father``s educational level, the presence of chemical products in the inside, and the presence of mold were significant risk factors for children``s atopic dermatitis. The multivariate-adjusted odds ratio for the occurrence of children``s atopic dermatitis was 3.19 (95% confidence interval, 2.57-3.95) when subjects with and without parent``s history were compared. Conclusion: When fathers have a history of allergic disease, children tend to have atopic dermatitis.(Allergy Asthma Respir Dis 2014;2:377-382)

우리나라 성인의 치주질환과 식이패턴요인 -제5기 국민건강영양조사(2010년) 중심으로-

백경원 ( Kyung Won Paek ),이수진 ( Soo Jin Lee ),백종환 ( Joung Hwan Back ) 대한예방치과·구강보건학회 2015 大韓口腔保健學會誌 Vol.39 No.4

Objectives: This study was aimed to identify the socioeconomic factors, health behavior factors and dietary patterns that have an influence on the periodontal disease in adults. Methods: This study used data collected from the fifth Korea National Health and Nutrition Examination Survey (NHANES V-1). The final sample included 2,386 subjects who were 30-59 years old and who had completed the necessary health examinations, the health behaviors survey and nutrition survey. Results: Eleven dietary patterns emerged from the factor analysis with different factor loading. After controlling for potential confounders, multiple logistic regression analysis of the dietary patterns showed that ‘legumes/mixed grains’ and ‘instant foods’ affected the periodontal disease. Lower consumption of ‘legumes/mixed grains’ and higher consumption of ‘instant foods’ were significantly associated only with an increased risk of periodontal disease. Conclusions: In the light of the results of this study, it appears pretty likely that the risk of developing periodontal disease can be reduced by changing a person’s dietary patterns.

한국 지역사회 노인의 사회적 활동과 인지기능의 연관성

조우동(Woodong Jo),손상준(Sang Joon Son),이윤환(Yunhwan Lee),백종환(Joung Hwan Back),노재성(Jai Sung Noh),고상현(Sang Hyun Koh),김현정(Hyun Chung Kim),김진주(Jinju Kim),박미애(Mi Ae Park),홍창형(Chang Hyung Hong) 대한노인정신의학회 2012 노인정신의학 Vol.16 No.1

Objectives:Among non-pharmaceutical measures for preventing cognitive impairment, involving in social activities is known to be very effective. We tried to examine the correlation between social activity and cognitive function. Methods:This study was based on the Suwon Project, a cohort comprising of non-random convenience samples of ethnic Koreans aged 60 years and above. All the subjects completed the study questionnaire which included demographic characteristics, current and past history of illnesses, drug history, Korean version of Mini Mental State Examination (K-MMSE), Korean version of Short Form Geriatric Depression Scale, and Beck Anxiety Inventory. We checked the time consumed in each 9 social activities through the checklist. Results:On multiple logistic regression analysis, the total time spent in social activities wasinversely associated with the K-MMSE score after adjusting confounding variables like age, sex, education level, depression, anxiety and vascular risk factor (β= -0.041, p=0.024). On the other hand, correlation was found between K-MMSE score and time spent in participating in religious party (β=0.053, p=0.003) as well as time spent in elder’s university (β=0.040, p=0.025) after adjustingage, sex, education, depression, anxiety and vascular risk factor. Conclusion:Our results suggest that involving in quality social activities might be more effective in improving cognitive function than spending longer total time in any social activity.

지역사회 노인의 인지기능과 정신적 활동의 연관성

여현철(Hyun Chul Yuh),고상현(Sang Hyun Koh),이윤환(Yunhwan Lee),백종환(Joung Hwan Back),임기영(Ki Young Lim),김현정(Hyun Chung Kim),홍창형(Chang Hyung Hong) 대한노인정신의학회 2011 노인정신의학 Vol.15 No.1

Objectives:The purpose of this study was to describe the status of mental activity participation in community-dwelling elderly and to evaluate the association between mental activity and cognitive function after adjustment for depression and anxiety. Methods:This study was based on the Suwon Project, which was a cohort comprising of nonrandom convenience samples of ethnic Koreans aged 60 years and above. All the subjects completed the study questionnaire including their demographic characteristics, current and past illnesses history, drug history, Korean version-Mini Mental State Examination (K-MMSE), Korean version of Short Form Geriatric Depression Scale (SGDS-K), Beck Anxiety Inventory (BAI). We checked how many hours per day are used for each items of 11 mental activities through the checklist. Results:Total time spent in 11 mental activities was 237.4±152.4 minutes per day. On multiple regression analysis, total time spent in 11 mental activities (MA-total), and time spent by watching television and reading book/newspaper showed statistically significant association with K-MMSE score after adjustment with age, sex, education, chronic medical illness, depression and anxiety. Conclusion:Our result suggested that mental activity may be associated with cognitive function in the elderly without cognitive impairment in the community after adjusting age, sex, education, chronic medical illness, depression and anxiety.

고혈압, 당뇨병을 제외한 대사증후군과 치주질환간의 연관성 분석

이수진 ( Soo Jin Lee ),홍윤미 ( Yoon Mi Hong ),백종환 ( Joung Hwan Back ),남영신 ( Young Sin Nam ) 대한예방치과·구강보건학회 2009 大韓口腔保健學會誌 Vol.33 No.3

Objectives: This study was to examine the relationship between metabolic syndrome(MetS) risk factor of cardiovascular disease and periodontal disease except patients with hypertension and type 2 diabetes mellitus. Methods: Data from the 2005 Korean National Health and Nutrition Examination Survey III were used for the analysis. The study population consisted of 1,611 persons (623 males and 988 females) aged 40 to 64 years. The diagnostic criteria of MetS based on the National Cholesterol Education Program Adult Treatment Panel III. The definition of MetS requires the presence of 3 or more of 5 components: abdominal obesity, triglyceride level, high-density lipoprotein cholesterol level, blood pressure, and fasting blood sugar level. Periodontal disease was defined by dentist`s diagnosis. Results: The prevalence of periodontal disease was greater in patients with MetS compared to those without MetS. In multivariate analyses, gender, age, education level, smoking habits, physical exercise, stress, interdental brush use, number of diseases, and MetS were significant risk factors for periodontal disease. The multivariate-adjusted odds ratio for the occurrence of periodontal disease was 1.45(95% confidence interval 1.02-2.05) when subjects with and without MetS were compared. Conclusions: MetS was significantly associated with periodontal disease. Therefore, the study of metabolic abnormality and periodontal disease must be performed continuously.

지역사회 노인에서 불안과 뇌졸중 경고증상의 관계

이수현(Su Hyun Lee),고상현(Sang Hyun Koh),이윤환(Yunhwan Lee),백종환(Joung Hwan Back),정영기(Young Ki Chung),김현정(Hyun Chung Kim),홍창형(Chang Hyung Hong) 대한노인정신의학회 2011 노인정신의학 Vol.15 No.1

Objectives:We aimed to investigate the relationship between anxiety and stroke warning signs in the elderly. Methods:Data obtained from 1,078 subjects (256 men and 822 women) aged above 65 years was analyzed from Suwon Project, which was a cohort comprising of nonrandom convenience samples. All the subjects completed the study questionnaire including their demographic characteristics, history of current and past illnesses, drug history, Korean version-Mini Mental State Examination (K-MMSE), SGDS-K (Korean version of the Geriatric Depression Scale-Short Form), BAI (Beck Anxiety Inventory). Stroke warning signs were defined as 5 stroke warning signs consistent with the American heart association public health message Results:There was significant relationship of anxiety and the number of stroke warning signs after adjusting age, sex, educational level and depression (β=2.145, p〈0.0001). On analysis of covariance, the interaction of the number of experienced stroke warning signs with sex on anxiety was observed after adjusting for the age, educational level, K-MMSE, and SGDS-K (p=0.011). Conclusion:These results suggest that there was significant relationship of anxiety and stroke the elderly.