Speculoscopy as Pap Smear Adjunct

박충학 ( Choong Hak Park ) 대한산부인과학회 2002 대한산부인과학회 학술대회 Vol.88 No.-

Conventional Papanicolaou cervical cytologic screening in women for health check-up

박충학 ( Choong Hak Park ),( Jin Wan Park ),( Man Chul Park ),( Young Hoon Suh ),( Jai Hyang Go ),( Ho Jang Kwon ) 대한산부인과학회 2004 대한산부인과학회 학술대회 Vol.90 No.-

난소 해면상혈관종

박충학(Choong Hak Park) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.7

Hemangioma of the ovary is very rare benign tumor and it is surprising that only about 40 examples have been reported. It is so rare that there is no report in Korean Journal of Obstetrics and Gynecology. There are both benign and malignant lesions of various histologic types in pure mesenchymal tumors of the ovary. Hemangioma of the ovary is benign tumor of vascular origin in this pure mesenchymal tumors of the ovary. Hemangioma of the ovary is considered either a hamartomatous malformation or a true neoplasm and may be associated with hemangiomas in other parts of the genital tract and with hemangiomatosis. Nearly all ovarian hemangiomas show histologically a cavernous or a mixed cavernous-capillary pattern with large vascular spaces. The hemangiomas are usually unilateral and asymptomatic but associated findings may include abdominal swelling and awareness due to the large mass, acute abdominal pain from torsion, ascites, and thrombocytopenia. I have experienced a very rare case of cavernous hemangioma with calcification in the right ovary, combined with mature cystic teratoma in the left ovary in a 22-year-old woman and report it with brief review of literatures.

저등급 자궁내막간질육종

박충학(Choong Hak Park),주선하(Seon Ha Joo),박호범(Ho Beom Park),서영훈(Young Hoon Suh),김동희(Dong Hee Kim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.1

Uterine sarcomas are relatively rare tumors of mesodermal origin that constitute 2-6% of uterine malignancies. Uterine sarcomas include endometrial stromal sarcoma (ESS), leiomyosarcoma (LMS), malignant mixed m llerian tumor (MMMT) of both homologous and heterologous type, pure heterologous sarcomas, blood vessel sarcomas, and lymphoma. Endometrial stromal tumors are divided into three types: 1) endometrial stromal nodule, 2) low-grade stromal sarcoma or endolymphatic stromal myosis, and 3) endometrial stromal sarcoma. The low grade endometrial stromal sarcoma is very rare. It shows occasional local recurrence, which might arise from endometrial stroma, from adenomyosis, and rarely from endometriosis. We have experienced a case of low grade endometrial stromal sarcoma of the uterus in a 54-year-old woman, which is presented with a review of literatures.

자궁경부종양 환자에서 polymerase chain reaction 방법에 의한 인유두종바이러스 16형과 18형 검출에 관한 연구

박충학 ( Choong Hak Park ),김재경 ( Jae Kyoung Kim ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.10

목적: 자궁경부종양 환자들에서 인유두종바이러스 16형과 18형의 감염률을 조사하고 그 임상적 의의를 알아보고자 하였다. 연구 방법: 21세에서 83세 사이의 여성 708명에게 고식적인 Pap 자궁경부 세포검사와 polymerase chain reaction 방법에 의한 인유두종바이러스 검사를 시행하였으며, 383예에서는 조직검사를 하였다. 결과: 708명의 세포검사에서 인유두종바이러스 검사는 편평세포암에서는 11예, 고등급 편평세포상피내병변에서는 41예, 저등급 편평세포상피내병변에서는 20예, 비정형 편평세포에서는 41예, 그리고 음성 세포진에서는 86예에서 양성으로 나왔다. 383예의 조직검사에서 인유두종바이러스 검사는 편평세포암에서는 24예, 자궁경부상피내종양 3에서는 42예, 자궁경부상피내종양 2에서는 12예, 자궁경부상피내종양 1에서는 12예, 비정형 변화 7예, 그리고 음성 조직진에서는 45예에서 양성으로 나왔다. 인유두종바이러스 검사가 음성인 239예에서 28.5%가 자궁경부상피내종양 1 이상의 조직학적 진단을 보였다. 자궁경부 세포검사가 음성이면서 인유두종바이러스 검사가 양성인 46예에서 50%가 자궁경부상피내종양 1 이상의 조직학적 진단을 보였다. 자궁경부 Pap 세포검사는 민감도 72.5%, 특이도 66.4%, 위음성률 27.5%를 보였으며, 인유두종바이러스 검사는 각각 57.5%, 76.7%, 42.5%를 보였다. 결론: 이 연구는 자궁경부 Pap 세포검사와 인유두종바이러스 검사는 상호 보완적이라는 사실을 확인시켜 준다. 자궁경부종양을 진료함에 있어 의사는 자궁경부 Pap 세포검사나 인유두종바이러스 검사를 과대평가해서는 안 된다. 이 두 가지 검사를 병합함은 자궁경부종양의 진단에서 정확성을 더욱 향상시킨다. Objective: The purpose of this study was to evaluate the detection rate of human papillomavirus (HPV) DNA Test (type 16 and 18) and to investigate the clinical significance of HPV DNA test in patients with cervical neoplasia. Methods: Of the 708 patients aged 21~83 years who had undergone both conventional Papanicolaou cervical cytologic test and HPV DNA test by polymerase chain reaction, 383 cases underwent histologic diagnoses. Results: Of the 708 cytologic diagnoses, there were 11 positive HPV DNA test diagnoses in squamous cell carcinoma (SCC), 41 in high-grade squamous intraepithelial lesion (HSIL), 20 in low-grade squamous intraepithelial lesion (LSIL), 41 in atypical squamous cells (ASC), and 86 in negative cytology. Of the 383 histologic diagnoses, there were 24 positive HPV DNA test diagnoses in SCC, 42 in cervical intraepithelial neoplasia (CIN) 3, 12 in CIN 2, 12 in CIN 1, 7 in atypical change, and 45 in negative histology. Of the 239 patients with negative HPV DNA test, 28.5% cases showed histologic diagnoses of CIN 1 or worse lesion. Of the 46 patients with negative cytology and positive HPV DNA test, 50.0% cases showed histologic dianoses of CIN 1 or worse lesion. Pap cytology revealed sensitivity of 72.5%, specificity of 66.4%, and false negative rate of 27.5%, whereas HPV DNA test showed 57.5%, 76.7%, and 42.5 %, respectively. Conclusion: This study confirmed that the primary standard Pap cytology and HPV DNA test were adjunctive. Also this study showed that physicians always should not overrate Pap cytology or HPV DNA test in managing the patient with cervical neoplasia. Combined test was a very effective diagnostic method for detecting cervical neoplasia.

초음파로 진단된 태아 심종양

조현철 ( Hyun Chul Cho ),박충학 ( Choong Hak Park ),박만철 ( Man Chul Park ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.11

고강도 집속 초음파(HIFU) 후 임신 제 2 삼분기에 발생한자연 자궁파열 1예

강윤단 ( Yun Dan Kang ),박충학 ( Choong Hak Park ) 대한주산의학회 2015 Perinatology Vol.26 No.4

자궁파열은 드물게 발생하지만, 치명적인 질환으로 모성과 태아의 이환율 및 사망률이 매우 높은 산과적 응급질환 중 하나이다. 가임기 여성에서 최근 자궁근종의 치료로 고강도 집속 초음파가 시행되고 있으나 시술 후 임신을 했을 때 자궁파열을 초래할 수 있지만 임신의 예후 및 시술에 관한 적응증, 지침은 부족한 상황이다. 이에 저자들은 자궁근종의 치료를 위해 고강도 집속 초음파 후 임신 25주에 자궁파열이 된 1예를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Uterine rupture during pregnancy does not occur frequently, but is associated with high rates of maternal and perinatal morbidity and mortality. As a non-invasive and conservative approach, high-intensity focused ultrasound (HIFU) has received attention from both gynecologists and patients for the treatment of fibroids, especially women who wish to preserve uterus. However, there are not enough studies about complication and prognosis related pregnancy after HIFU. We present a case of uterine rupture that occurred in second trimester who had been HIFU 3months before pregnancy.

자궁경부 세포진 검사상 미확정 비정형 편평세포 (ASCUS) 환자에서 자궁경부 확대촬영술의 임상적 효용성에 관한 연구

박호범 ( Ho Beom Park ),서영훈 ( Young Hoon Suh ),박충학 ( Choong Hak Park ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.2

방법 : 2000년 1월 1일부터 2000년 7월 31일까지 만 7개월 간 단국대학교의료원 산부인과 외래 Clinic을 방문한 환자 중 자궁경부 상피내종양 및 자궁경부암이 의심되는 환자에서 자궁경부 세포진검사와 자궁경부 확대촬영검사를 실시한 120예 중 TBS 기준에 의거한 세포진검사의 진단이 ASCUS로 나온 30예를 대상으로 하여 자궁경부 확대촬영검사의 진단과 최종적인 병리조직학적 검사의 진단을 비교-분석하였다. 연구 목적 : 자궁경부 세포진 검사상 Objective : The purpose of this study was to investigate the correlation between the cervicographic diagnoses and histologic diagnoses in patients with ASCUS cytologic diagnosis according to The Bethesda System. Methods : This study was performed in outpa

항암치료에 반응하는 난소암 환자에서 항-Yo항체가 있는 부신생물 소뇌퇴행증

송승훈 ( Seung Hun Song ),박충학 ( Choong Hak Park ),박진완 ( Jin Wan Park ) 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.12

Paraneoplastic cerebellar degeneration (PCD), the one of rare paraneoplastic syndromes, refer to clinical disorders associated mostly with lung, ovarian and breast cancer, but not directly caused by cancer or its metastasis. PCD is a condition whereby the Purkinje cells of the cerebellar cortex are damaged secondary to an autoimmune process. We report here on the case of PCD of subacute onset in a patient at 7 months after surgery for ovarian cancer. Although the cases of PCD has rarely been reported, the present case appears to be the first in Korea in which PCD was associated with anti-Yo antibody in patient with chemotherapy-responsive ovarian cancer. The clinical significance of PCD associated with anti-Yo antibody is reviewed.

복식 전자궁 절제술 후 통증자가조절을 통하여 Ketorolac과 함께 투여한 Butorphanol과 Nalbuphine의 효과

김동희(Dong Hee Kim),박충학(Choong Hak Park) 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.2

N/A Background: This study was designed to know the dose requirement, analgesic efficacy and side effects of butorphanol and nalbuphine when administered with ketorolac by patient controlled analgesia (PCA) after total abdominal hysterectomy. Methods: Forty women who underwent total abdominal hysterectomy received ketorolac (bolus dose 2.4 mg, lockout interval 10 min) with either butorphanol (bolus dose 0.1 mg) or nalbuphine (bolus dose 1 mg) using PCA pump postoperatively. Results: Total amounts of 48 hr consumption were 8.7 mg (butorphanol)and 61.5 mg (nalbuphine). There were no significant differences between two groups in total ketorolac infusion doses, VAS score and side effects. Conclusions: Both butorphanol and nalbuphine were useful for PCA for postoperative pain control. We may suggest that ketorolac 180 mg with butorphanol 9 mg or nalbuphine 70 mg would be useful for 48 hr postoperative pain eontrol.