비알콜성지방간의 유병율과 병리기전에 대한 문헌적 고찰

박연화,유사라,손창규,Park, Yeun-Hwa,Yoo, Sa-Ra,Son, Chang-Gue 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.1

Objectives : Non-alcoholic fatty liver disease (NAFLD) is known to be increasing and becoming a health-related issue worldwide. This study aimed to analyze its prevalence and characterize NAFLD. Methods : NAFLD-related papers were surveyed via PubMed and in Korean medical journals, and then the prevalence and pathology were reviewed. Results : The prevalence of NAFLD in the general population is around 10~30% worldwide. The prevalence of NAFLD in Korea is estimated as 15~30%, which is higher than in China and Japan. The most important etiological-factors of NAFLD include central obesity resulting from excessive calorie intake and less physical activity, which lead to adiponectin hypoactivity and insulin resistance. The Oriental medicine view point of NAFLD pathology is phlegm-dampness by dysfunction of free flow in liver. Conclusions : This study provided an overview of the prevalence and pathology of NAFLD, and can support the development of a strategy for traditional Korean medicine-based prevention or treatment of NAFLD.

건강검진 대상자에서 대장용종의 위험요인 분석

박연화(Park, Yoen-Hwa),유지현(Yu, Ji-Hyun),이태용(Lee, Tae-Yong) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.3

본 연구는 대장 용종 발생의 위험인자를 파악하기 위해 종합검진 수검자 중 대장내시경 검사와 복부초음파 검사를 동시에 시행 받은 508명을 대상으로 나이, 성별, 흡연, 음주, 운동의 일반적인 특성과 신장, 체중, 혈압, 허리 둘레, 체질량 지수 등의 신체 계측을 하였으며, 동시에 채혈을 통한 공복 시 혈당과 여러 가지 혈액검사를 분석하였 다. 그 결과 AST, ALT, 총콜레스테롤, 지방간, 비만도 및 흡연여부가 유의하게 높은 것으로 나타났으며 대장용종이 있는 대상자가 지방간과의 관련성이 3.4배로가 가장 높았고, 다음으로 총콜레스테롤 2.3배, 흡연자가 비흡연자에 비해 2.3배나 위험성이 높게 나타났다. This study aimed to analyze the occurrence of colon polyps and also risk factors of colon polyps. Among health examination examinees, 508 peoplewere included who underwent colonoscopy and abdominal ultrasonography at the same time. Physical measurements also performed such as height, weight, blood pressure, waist measurement and BMI. General characteristics including age, sex, smoking, drinking and exercise as a risk factors were checked. At the same time, we analyzed various blood tests and fasting blood sugar through blood-gathering. In the results, regarding risk factors of colon polyps, AST, ALT, TC, fatty liver, obesity and smoking were shown significantly high. As a dependent variable with colon polyps, the highest relation was fatty liver(3.4 times), and then T-C(2.3 times). Smoking factor showed 2.3 times higher relation than non-smokers.

건강검진 수진자에서 담낭용종과 생화학적검사, 대사증후군 및 생활습관의 관련성

박연화(Park, Yoen-Hwa),강재선(Kang, Jae-Sun),이혜남(Lee, Hea-Nam) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.2

최근, 복부초음파로 인해 담낭용종의 발견률이 높아지고 있다. 담낭용종의 위험인자에 대한 다양한 연구가 보고 되었지만 생화학검사, 생활습관을 포함한 대사증후군과 담낭용종의 관계에 대한 연구가 미흡한 실정이다. 본 연구의 목적은 생활습관, 생화학적 혈액검사를 포함한 대사증후군과 담낭용종과의 관련성을 알아보는데 있다. 2013년 1월부터 2013년 12월 까지 건강검진 수진자 중 복부초음파검사를 시행 받아 담낭용종의 진단을 받은 596명을 대상으로 나이, 성별, 흡연, 음주, 운동의 일반적인 특성과 신장, 체중, 혈압, 허리둘레, 체질량 지수 등의 신체 계측을 하였으며, 동시에 채혈을 통한 공복 시 혈당과 여러 가지 혈액검사 및 대사증후군 여부를 분석하여 담낭용종과의 관계를 알아보았다. 그 결과 남성, 흡연자, 비음주 자에서 유의하게 높았으며, 체질량지수가 높을수록, 대사증후군이 있는 집단이, HBsAg 양성군에서 높았고, 위험도는 남성이 여성보다 1.8배, 대사증후군이 있는 군이 없는 군보다 2.3배, HBsAg이 양성인 군에서 2.6배 높게 나타났다. The incidence of gallbladder polyps are increasing due to the extended use of ultrasonography. Although there are various reports on the risk of gallbladder polyps, there are few studies of the relationships among the presence of metabolic syndrome including serum biochemistry, lifestyle and the development of gallbladder polyps. The aim of this study was to determine association of the presence of metabolic syndrome, including serum biochemistry, with the development of gallbladder polyps in the Korean population. Among the health examination examinees, 596 people, who underwent abdominal ultrasonography from January, 2013 to December 2013, were included in this study. Physical measurements also taken, such as height, weight, blood pressure, waist measurement, and BMI. The general characteristics including age, sex, smoking, and drinking as the related factors were checked. At the same time, various blood tests were performed and the fasting blood sugar was analyzed through blood-gathering to determine the presence of metabolic syndrome. Regarding the factors associated with gallbladder polyps, the results showed that being male, smoking, non-drinking were significantly high. In addition, testing positive for HBsAg and an increasing BMI was apparently higher the group with metabolic syndrome than the non-metabolic syndrome group. The highest predictive factors for gallbladder polyps was being male (1.8 times), followed by metabolic syndrome (2.3 times) and testing positive for HBsAg (2.6 times).

냉매부문 온실가스 감축을 위한 외부감축사업 활용에 관한 조사 연구

박연화(Park, Yeon-Hwa),인은정(In, Eun-Jeong),김홍록(Kim, Hong-Rok) 한국기후변화학회 2016 한국기후변화학회지 Vol.7 No.3

정서․정보적 지지중재가 뇌졸중입원환자를 돌보는 가족원의 부담감과 우울에 미치는 효과

정경숙(Jeong, Kyeong Sook),박연화(Park, Youn Hwa),최금희(Choi, Gum Hee),박금자(Park, Geum Ja) 고신대학교 전인간호과학연구소 2015 전인간호과학학술지 Vol.7 No.-

Purpose: The purpose of this study was to identify the effect of emotional and informational support intervention on the burden and depression of primary family caregivers caring hospitalized stroke patients. Method: The research was a quasi-experimental study using a nonequivalent control group non-synchronized design. The participants were 30 primary family caregivers, 15 in the experimental group and 15 in the control group. A pre-test and a post-test were conducted to measure main variables. The emotional and informational support intervention program was executed 2 times for 2 weeks. Program consisted of education about stroke by guidebook and counseling, was given for the experimental group. Data were analyzed using χ2, Fisher s exact test, and independent t-test with SPSS 14.0 program. Results: There were statistically significant decrease in burden, but depression was not statistically significant by difference between a pre-test and a post-test in the experimental group compared to that in the control group. Conclusion: The result of this study indicate that the Emotional and Informational Support Intervention program was effective in decreasing burden although not statistically significant reduction in depression. Therefore, it can be a way to reduce burden of primary caregivers caring stroke patients.

가습기살균제 피해자의 생애사 연구: 꿈 많은 연예인지망생에서 죽음의 공포를 경험하는 건강피해자로

황동욱 ( Hwang¸ Dong Wook ),박연화 ( Park¸ Yeon Hwa ),최성문 ( Choi¸ Sung Moon ) 이화여자대학교 사회복지연구소 2021 사회복지 실천과 연구 Vol.18 No.3

본 연구에서는 가습기살균제 피해자의 생애사 연구 방법을 중심으로 피해자가 어떤 과정과 경로를 통해 가습기살균제 피해자가 되었으며 이에 국가나 사회의 역할을 재조명하고, 피해자 지원제도의 문제점과 실태를 파악하여 사회복지적 함의 및 지원방안을 마련하기 위한 탐색을 목적으로 수행되었다. 심층면접 자료분석은 맨델바움(1973)이 제시한 3가지 분석 범위인 ‘삶의 영역(dimension)’, ‘전환점(turning point)’, ‘적응(adaptation)’을 적용하였다. 분석결과 삶의 영역은 ‘꿈많고 자신감 넘쳤던 성장기’, ‘나를 위한 선택, 가습기살균제’, ‘병원을 다녀도 원인을 모른다는 건강이상’,‘아무도 믿어주지 않는 환자’, 전환점은 ‘재능 발견과 적극적인 도전’, ‘독립 이후 찾아온 죽음의 공포’, ‘나를 지키기 위한 시작 피해자 신청, 인정해주지 않는 국가와 기업’, 적응은‘꿈보다 현실을 직시’, ‘아무것도 할 수 없는 ‘나’로 인한 좌절‘, ‘함께하는 외침, 가습기살균제 피해구제 모임 활동’으로 도출되었다. 이러한 결과에 의거해, 가습기살균제 피해자에 대해 국가와 사회의 신속하고 실효적인 지원을 할 수 있는 제도마련, 전국적으로 분포하고 있는 가습기살균제 피해자를 위한 다부처 협력 및 보건복지부 지원체계의 필요성, 가습기살균제 피해자의 회복탄력성을 위한 사회복지서비스 제공 및 피해자단체 지원을 제언하였다. This study was conducted to investigate the social welfare implications and support measures by re-examining the role of the state and society, and identifying the problems and actual conditions of the victim support system, focusing on the life history research method of the victim of humidifier disinfectant. In-depth interview data analysis was conducted using Mandelbaum(1973)'s 'dimension', 'turning point', and 'adaptation'. Results of the analysis showed that the dimensions were 'growth period that was full of dreams and confidence', 'choice for me, humidifier disinfectant', 'health problems that even the doctors do not know the cause of', and 'a patient that no one believes'. The turning points were 'talent discovery and active challenge', 'horror of death after independent living', 'start to protect me, victim application,' and ‘governments and companies that don't admit’. The adaptation was derived as 'facing the reality rather than dreams', 'frustration of me being unable to do anything', 'collectively screaming and doing activities to relieve humidifier disinfectant damage'. Based on these results, we proposed a system to provide rapid and effective support to humidifier disinfectant victims from the government and society, the need for cooperation from various ministries for humidifier disinfectant victims distributed nationwide, and the need for health and welfare support system that provide social services and support for the recovery of humidifier disinfectant victims.

비만 및 골다공증 예방에 대한 conjugated linoleic acid (CLA)의 생리활성 대사 연구

김준호(Jun Ho Kim),김종건(Jonggun Kim),박유헌(Yooheon Park),박연화(Yeonhwa Park) 한국식품과학회 2010 식품과학과 산업 Vol.43 No.4