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양동훈 ( Yang Dong Hun ),명승재 ( Myeong Seung Jae ),장혜숙 ( Jang Hye Sug ),송진우 ( Song Jin U ),양석균 ( Yang Seog Gyun ),이진혁 ( Lee Jin Hyeog ),정훈용 ( Jeong Hun Yong ),홍원선 ( Hong Won Seon ),김진호 ( Kim Jin Ho ),민영일 대한소화기학회 2003 대한소화기학회지 Vol.42 No.6
Enteropathy-associated T-cell lymphoma (EATL) is an unusual primary gastrointestinal lymphoma, particularly associated with celiac sprue. This tumor usually affects the jejunum and grossly presents as multiple circumferential ulcers without the formation of definite tumor masses. Moreover, mesenteric lymph nodes are commonly involved. The patients have typically suffered from abdominal pain, diarrhea, or weight loss whereas some patients may manifest with nonspecific symptoms for a period of years or an acute emergency of perforation, obstruction, or hemorrhage. The clinical course of EATL is very unfavorable and the prognosis is poor. Both celiac sprue and EATL are very rare diseases in Asia, except India and Middle East. We report a 60-year-old male diagnosed as having EATL after segmental small bowel resection, who presented with recurrent gastrointestinal bleeding. (Korean J Gastroenterol 2003;42:527-532)
염증성 장질환에서의 당질 코르티코이드에 대한 불응성 판정을 위한 당질코르티코이드 β 수용체의 유용성
양성연 ( Sung Yeun Yang ),명승재 ( Seung Jae Myung ),양석균 ( Suk Kyun Yang ),장혜숙 ( Hye Sook Chang ),정훈용 ( Hwoon Yong Jung ),홍원선 ( Weon Seon Hong ),김진호 ( Jin Ho Kim ),민영일 ( Young Il Min ),오현주 ( Hyun Ju Oh ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> 염증성 장질환의 치료에 당질 코르티코이드는 효과적인 약물로 사용되고 있다. 그러나, 증례에 따라서 반응의 정도가 다르며 불응성 증례의 경우 심각한 합병증을 초래할 수 있어 당질 코르티코이드의 투여 전 반응 여부를 미리 예측할 수 있다면 임상적으로 매우 유용한 정보가 될 것이다. 당질 코르티코이드 수용체는 α와 β로 이루어져 있으며 최근 말초 혈액 단핵구에서 β 수용체의 발현이 양성인 경우 당질 코르티코이드의 반응이 저하된다는 보고가 있으나 아직
체외 충격파 쇄석술 및 내시경적 유두 괄약근 절개술로 제거된 총담관 거대 담석 2예
민영일(Young Il Min),이영상(Young Sang Lee),김해련(Hae Ryun Kim),김명환(Myung Hwan Kim),정영화(Young Hwa Joung),민병철(Pyung Chul Min),양석균(Suk Kyun Yang),임채만(Chai Man Lim),이승규(Sung Kyu Lee),조경석(Kyung Shik Cho) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.3
We have performed extracorporeal shock-wave lithotripsy for fragmentation in the two patients with 3 cm sized single common bile duct stone, who had been cholecystectomized previously. After ESWL, multiple stone fragments were completely removed by endoscopic papillotomy and balloon extraction.
민영일(Young Il Min),이영상(Yung Sang Lee),이성구(Sung Koo Lee),양석균(Suk Kyun Yang),박선미(Seon Mee Park),김형호(Hyeung Ho Kim),송준서(Joon Seo Song),이인철(In Cheul Lee) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.2
Seven cases of primary biliary cirrhosis were reported so far in Korea. We experienced two cases of this disease. One, 47-year-old woman who complained pruritus, easy fatigability, xerostomia and xeropthalmia for 5 years, is diagnosed primary biliary cirrhosis associated with Sjogren's syndrome. The other, 44-year-old woman, who has previous history of Bechet's disease, suffered from arthralgia and jaundice. They showed cholestatic type of liver dysfunction, but had no obstructive lesion in biliary trees. We tried to treat with cholestyramine and ursodeoxycholic acid. We reviewed and summerized all the other reported cases in Korea.
경구 Nitrate 제재 투여로 호전된 Biliary Dyskinesia
민영일(Young Il Min),이영상(Yung Sang Lee),김해련(Hae Ryun Kim),이성구(Sung Koo Lee),김명환(Myung Hwan Kim),정영화(Young Hwa Joung),양석균(Suk Kyun Yang),전용철(Yong Cheol Jeon) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2
Biliary dyskinesia is a functional disorder of the biliary tracts, especially spasm of the sphincter of Oddi (SO). It is sometimes impossible to differentiate patients with true biliary dyskinesia from those patients with papillay stenosis, which is a structual narrowing of SO segment. We report a case of biliary dyskinesia diagnosed and treated by nitrates. The paitent has suffered from chronic liver disease and admitted to our hospital due to biliary pain and aggravated liver function. On biliary manometry, the basal pressure of SO phasic contractions and common bile duct pressure were increased. Also tachyoddia and increased retrograde propagation of phasic contractions were observed. After intravenous injection of nitrate, the basal pressure of SO were decreased and phasic contractions disappeared within 30 seconds. She was diagnosed as biliary dyskinesia and treated by long acting oral nitrates. And then, her symptoms were disappeared and liver function was improved.
간장 ( 肝臟 ) 및 담도 ( 膽道 ) : 만성 간질환 환자에서 혈청 Alpha - Fetoprotein 치의 비특이적 상승을 유발하는 요인에 관한 연구
민영일(Young Il Min),정영화(Young Hwa Chung),양석균(Suk Kyun Yang) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.4
N/A The factors and mechanisms that elevate serum alpha-fetaprotein (AFP) in patients with non-malignant chronic liver disease have not been well known. The present study was designed to find factors contributing to nonspecific increase of serum AFP in these patients. We have also reviewed possible mechanisms of increased serum AFP that may explain our results. The results were summarized as follows; 1) Serum AFP levels did not. correlate to either age or sex. 2) Serum AFP levels correlated with serum alanine aminotransferase (ALT) levels only at low degree (r.=0.219, P=0.03). 3) Eight patiente whose serum AFP levels were 400 ng/ml or more were all seropositive for HBsAg. However, there was no statistical difference in srum AFP levels between patients with (n=65) and without (n=12) HBsAg. 4) Eleven patients whose serum AFP levels were 200 ng/ml or more were all seropositive for HBeAg, and there was statistical difference in serum AFP levels between patients with (n=41) and without (n=ll) HEleAg(p<0.05). In conclusion, hepatic necrosis per se does not seem to be directly responsible for serum AFP elevation in patients with nonmalignant chronic liver disease. The possible mechanism for increased serum AFP in theee patients is abnormal or aitered liver cell regeneration, which may be associated with hapatitis B virus.
위장관 ( 胃腸管 ) : 노출혈관을 동반한 소화성 궤양 출혈환자에 대한 레이저 지혈요법
민영일(Young Il Min),정영화(Young Hwa Chung),양석균(Suk Kyun Yang) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.4
N/A we have assessed the efficacy and safety of endoscopic LASER therapy following injection of 1:10,000 eplnephrine solution in 36 patients with bleeding peptic ulcers, in whom an exposes vessel or sentinel clot was indentified.1) 15 of 16 patients (94%) with actively bleeding vessels could be controlled successfully by the combined therapy with epinephrine injection and LASER photocoagulation. 2) 30of total 36 patients (83%) with exposed vessels showed no recurrent bleeding within 72 hours after initial treatment with epinephrine injection and LASER ohotocoagulation.3) Among 5 patients with recurrent bleeding after initial treatment, the bleeding of 4 patients (80%) could be controlled by second trial.4) Ultimately, 34 of total 36 patients (94) with exposed vessels could be managed successfully by the combined treatment of epinephrine injection and LASER photocoagulation. 5) Complications related to LASER therapy follwing epinephrine injection were sepsis in a patient with deabetes melitus, and arterial spurtings in three patients which were successfully controlled by repeated LASER photocogulation.6) The overail morality in this study was 6% (2 patients); one seath was caused by sepsis, and the other was due to underlying hepatocellular carcinoma. In conclusion, the LASER therapy following epinephrine injection may be an effective and safe treatment of bleeding peptic ulcers with exposed vessels in the hemostasis and prevention of recurrence.