만성 연중독자에서의 다발성 뇌석회화 병변

김성률,최순섭,홍영습,정갑열,김준연,김병권,담도온 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3

We experienced a case of occupational lead poisoning employed in a secondary lead smelting plant for 12 years. The patient was 39-year-old male and had been felt dizziness, recent memory impairment and intermittent severe abdominal pain for 2 years. On admission, blood lead level was 92.9 ㎍/dl, urinary lead level was 19.9 ㎍/l and zinc protoporphyrin level was 226.0 ㎍/dl. On the blood test, hemoglobin was 10.6 g/dl and showed normocytic normochromic anemia. There were no abnormal findings in the biochemical and hormonal tests. Decrease of I.Q. and use of words in speaking were found in the psychiatric and psychologic examinations. We observed the finding of motor polyneuropathy in the nerve conduction velocity test. Computed tomographic finding showed calcification lesions in the basal ganglia, dentate nuclei, caudate nuclei, and especially characteristic multiple calcifications were located in the subcortical white.

용접흄 폭로 근로자들의 폐기능에 관한 연구

홍영습,김정만,김성률,정갑열,김준연,김병권,담도온 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3

In order to study the effect of welding fume exposure upon the pulmonary function test, we examined 131 shielded arc welding workers, and 152 CO₂arc welding workers as cases and 177 control workers for their general characteristics, and forced vital capacity (FVC), forced expiratory volume in one second (FEV 1.0), forced expiratory volume in one second as a percent of FVC (FEV1.0%), and maximal mid-expiratory flow (MMF) were obtained from the spirogram. In shielded arc welding group and CO₂arc welding group, FVC,FEV 1.0,FEV 1.0%, and MMF were significantly decreased than control group, especially marked in the MMF finding. The distribution of workers below normal range was as follows: in the shielded arc welding group, 2 workers(1.5%) for FVC, 17 workers(13.0%) for FEV 1.0, 5 workers(3.8%) for FEV 1.0, 28 workers(21.4%) for MMF, and in the CO₂arc welding group, 3 workers(2.0%) for FVC, 25 workers(16.4%) for FEV 1.0, 8 workers(5.3%) for FEV 1.0%, and 37 workers(24.3%) for MMF, and significant increase by exposure duration was found in MMF. The distribution of workers who had ventilation impairment was as follows: 5 workers(3.8%) for obstructive type, 2 workers(1.5%) for restrictive type in the shielded arc welding group, and 7 workers(4.6%) for obstructive type, 2 workers(1.3%) for restrictive type, and 1 worker(0.6%) was combined type of the CO₂arc welding group. In the respect of these results, the significant pulmonary function and ventilatory impairment were observed in welding fume exposed workers who had not abnormal finding in chest X-ray, and MMF considered as the most sensitive pulmonary function index by welding fume exposure. Therefore even if it is hard to doing pulmonary function test in the first health examination of workers according to the Industrial Safety Health Act in the welding fume exposure workers, it is desirable to consider doing PFT. Also evaluating the ventilation impairment, it is necessary to observe the change of MMF that marker of effort independent portion.

부산지역 일부 성인의 B형과 C형 간염의 유병률에 관한 연구

金埈淵,譚道溫,辛海林,鄭甲烈,金源述 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3

This study was carried how much prevalent Hepatititis C virus(HCV) and hepatitis B virus(HBV) infection among adults in Pusan. Study subjects(1,806) were examinee to take a multyiphasic health examination at a University hospital from July 1992 to June 1994. Serums were collected for tesr of anti-HCV, HBsAg and HBsAg, the level of SGOT, SGPT, r-GT, and stool examination was tested for clonorchiasis. All of the subjects were interviewd with the questionnaire of blood transfusion history, past history and familial history of hepatitis. The overall prevalence rate of anti-HCV was 2.95%(95% CI:1.58∼4.28), especially high in dlderly group, and overall prevalence of HBsAg was 7.4%(95% CI7.3∼8.5). The positive rate of anti-HCV was not siginificantly different between positive group of HBsAg and negative group of HBsAg. The positive rate of anti-HCV in normal group that had values within normal range of SGOT, SGPT, r-GT and normal findings of abdominal ultrasonogram, was 1.55%((95% CI:0.46∼2.64). The truncated age adjusted positive rate of anti-HCV for the Pusan population was 3.03%(95% CI:2.99∼3.07). Therefore the positive rates of anti-HCV and HBsAg for adults in Pusan area were relatively high, they should be considered to implement adquate control of Hepatitis B and C virus infection and reinforcemint of health education.

부산지역 일부 성인의 B형과 C형 간염의 유병률에 관한 연구

김원술,담도온,신해림,정갑열,김준연 釜山醫師會 1995 釜山醫師會誌 Vol.31 No.5

만성 연중독자에서의 다발성 뇌석회화 병변

김성률,김병권,홍영습,담도온,최순섭,정갑열,김준연,Kim, Sung-Ryul,Kim, Byoung-Gwon,Hong, Young-Seoub,Dam, Do-Won,Choi, Soon-Seob,Jung, Kap-Yull,Kim, Joon-Youn 대한예방의학회 1995 Journal of Preventive Medicine and Public Health Vol.28 No.2

We experienced a case of occupational lead poisoning employed in a secondary lead smelting plant for 12 years. The patient was 39-year-old male and had been felt dizziness, recent memory impairment and intermittent severe abdominal pain for 2 years. On admission, blood lead level was $92.9{\mu}g/dl$, urinary lead level was $19.9{\mu}g/l$ and zinc protoporphyrin level was $226.0{\mu}g/dl$. On the blood test, hemoglobin was 10.6g/dl and showed normocytic normochromic anemia. There were no abnormal findings in the biochemical and hormonal tests. Decrease of I.Q. and use of words in speaking were found in the psychiatric and psychologic examinations. We observed the finding of motor polyneuropathy in the nerve conduction velocity test. Computed tomographic finding showed calcification lesions in the basal ganglia, dentate nuclei, caudate nuclei, and especially characteristic multiple calcifications were located in the subcortical white matter.

용접흄 폭로 근로자들의 폐기능에 관한 연구

홍영습,김병권,김성률,담도온,김정만,정갑열,김준연,Hong, Young-Seoub,Kim, Byoung-Gwon,Kim, Sung-Ryul,Dam, Do-Won,Kim, Jung-Man,Jung, Kap-Yull,Kim, Joon-Youn 대한예방의학회 1995 예방의학회지 Vol.28 No.1

In order to study the effect of welding fume exposure upon the pulmonary function test, we examined 131 shielded arc welding workers, and 152 $CO_2$ arc welding workers as cases and 177 control workers for their general characteristics, and forced vital capacity (FVC), forced expiratory volume in one second $(FEV_{1.0})$, forced expiratory volume in one second as a percent of FVC $(FEV_{1.0}%)$, and maximal mid-expiratory flow (MMF) were obtained from the spirogram. In shielded arc welding group and $CO_2$ arc welding group, FVC, $FEV_{1.0},\;FEV_{1.0}%$, and MMF were significantly decreased than control group, especially marked in the MMF finding. The distribution of workers below normal range was as follows. in the shielded arc welding group, 2 workers(1.5%) for FVC, 17 workers(13.0%) for $FEV_{1.0}$, 5 workers(3.8%) for $FEV_{1.0}%$, 28 workers(21.4%) for MMF, and in the $CO_2$ arc welding group, 3 workers(2.0%) for FVC, 25 workers(16.4%) for $FEV_{1.0}$, 8 workers(5.3%) for $FEV_{1.0}%$, and 37 workers(24.3%) for MMF, and significant increase by exposure duration was found in MMF. The distribution of workers who had ventilation impairment was as follows: 5 workers(3.8%) for obstructive type, 2 workers(1.5%) for restrictive type in the shielded arc welding group, and 7 workers(4.6%) for obstructive type, 2 workers(1.3%) for restrictive type, and 1 worker(0.6%) was combined type of the $CO_2$ arc welding group. In the respect of these results, the significant pulmonary function and ventilatory impairment were observed in welding fume exposed workers who had not abnormal finding in chest X-ray, and MMF considered as the most sensitive pulmonary function index by welding fume exposure. Therefore even if it is hard to doing pulmonary function test in the first health examination of workers according to the Industrial Safety Health Act in the welding fume exposure workers, it is desirable to consider doing PFT. Also evaluating the ventilation impairment, it is necessary, to observe the change of MMF that marker of effort-independent portion.