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전병환 ( Byung Hwan Chun ),서성준 ( Seong Jun Seo ),김명남 ( Myeung Nam Kim ),홍창권 ( Chang Kwun Hong ),노병인 ( Byung In Ro ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.5
Backgroud: Female diffuse hair loss is a common baldness with a multifactorial origin. In recent studies, it has been suggested that reduced or depleted iron stores are a cause of female diffuse hair loss. Objeetive : We performed this study in order to elucidate the pathogenesis of female diffuse hair loss and to evaluate the differences in serurn iron levels between normal females and those with diffuse hair loss in Korea. Methods : Blood levels of hemoglobin, iron, TIBC, ferritin, testosterone, thyroid function, ANA and Zn were examined in 30 patients with female diffuse hair loss and 20 normal females. Results : 1) Serum Zn, testosterone, T4, TSH of the patient group were not statistically significant compared to those of the control group (p>0.05). 2) TIBC values were significantly increased, but serum ferritin levels were signifieantly decreased in the patient group (p<0.05). There were no significant differences in hemoglobin, serum iron in both groups (p>0.05). 3) No significant differences between clinical severity and the values of serum Zn, testosterone, T4, TSH, TIBC, serum femtin, hemoglobin and serum iron were observed (p>0.05). Conclusion : These findings suggested that the variations of TIBC, serum femtin levels may play a role in the pathogenesis of female diffuse hair loss, but further studies will be needed for evaluation of this condition. (Korean J Dermatol 1998;36(5) 865-870)
전병환,안건영,서성준,홍창권,노병인 ( Byung Hwan Chun,Gun Young Ahn,Seong Jun Seo,Chang Kwun Hong,Byung In Ro ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5
Sebaceous carcinoma is a rare malignant appendageal tumor of t.he skin and is usually located on the meibomian glands if the eyelid. We present a case of sebaceous carcinoma developed in a scapulir area. A 77-year old male had been suffering from a 3*2.5 cm sized ulcerated mass with an indurated margin an the left scapular area for 10 years. Histopathologirally, irregular, lobular formations were composed of sebaceous and undifferentiated cells showing considerable variation in the shape and size of their nuclei. We removed the lesion by surgical excision and could not find any recurrence for 30 months. (KOrear J Dermatol 1997;35(5): 1001-1004)
전병환,서성준,홍창권,노병인,허성호 ( Byung Hwan Chun,Seong Jun Seo,Chang Kwun Hong,Byung In Ro,Sung Ho Hue ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5
Sarcoidosis, a multisystemic disease of unknown cause characterized by the formation of noncaseat,ing granulomas, may involve any organ of the body. The most common sites of predilection are the lungs, lymph nodes, skin and eyes. Cutaneous sarcoidosis is seen in approximately 20-35% of patients with systcmic disease. Involvement of the central nervous system with sarcoidosis is relatively uncommon with an estimated incidence of only 3.5-5.0%. A 57-year-old male had been admitted to Department of Internal Medicine due to weight loss, polydipsia, polyuria, visual disturbance and bilateral hilar enlargement. He was diagnosed as sarcoidosis with diabetes inspidus by mediastinoscopic biopsy and a water deprivation test. On his first visit to dermatology he had several well-demarcated smooth-surfaced erythematous plaques on his forehead which had been there for 7 months. Histopathologically, many noncaseating epithelioid tubercles which are characteristic findings of sarcoidosis, were found in the dermis and subcutaneous tissue. We treated him with predniscilone 40 mg daily for 3 months and skin lesions markedly improved. (Korean J Dermatol 1997;35(5): 1013-1017)
노병인,홍창권,서성준,전병환 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.1
Tuberculosis verrucosa cutis is caused by the external inoculation of Mycobacterium tuberculosis into the skin of a person who already has a significant degree of cell mediated immunity to this organism. This form of cutaneous tuberculosis is less common. A 29-year-old male had a solitary adult palm sized, verrucous surfaced scaly plaque for about 10 years. The lesion was excised about 10 years ago but gradually increased in size. At first we suspected a deep mycosis and treated him with anti-fungal medication for 3 months. However, the skin lesion did not improve. He was then treated with anti-tuberculosis medication for 9 months under the impression of tuberculosis verrucosa cutis. The skin lesion was almost healed and no recurrence has been observed for 8 months after the treatment.
Two Cases of Pityriasis Versicolor on the Scalp in the Course of Treatment for Alopecia Totalis
Lee, Kang Seok,Chun, Byung Hwan,Ro, Byung In 대한의진균학회 1998 대한의진균학회지 Vol.3 No.1
Tinea capitis is a dermatophyiosis of the scalp and associated hairs that is caused by the species of genera Microsporum and Trichophyton. It commonly affects children. Black dot ringworm (BDR) can be caused by Trichophyton tonsurans and Trichophyton violaceum. We report a 82-year-old woman with diffuse hair loss and black dots oil the frontal scalp, and an erythematous annular scaly patches on the forehead. Endothrix invasion of the hair was shown on the 20% KOH mount. In fungus culture, slow growing violaceous verrucous colonies were obtained from the scalp and face. Microscopic findings revealed irregular branching hyphae and numerous chlamydospores. Histologic findings of the scalp showed numerous PAS positive fungal elements in the hair. Griseofulvin was administrated at the dose of daily 1000mg for 3 weeks, but no clinical and mycological improvement were obtained and tenderness and pustules were developed. Terbinafine at the dose of daily 250mg was administrated for 6 weeks, and clinical and mycologic improvement were obtained and damaged scalp hairs were replaced by intact hair shaft. There has been no recurrence for 8 months. To our best knowledge, this is the first case of BDR caused by T. violaceum in the Korean literature. [Kor J Med Mycol 3(1): 39-42]