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전병환,서성준,홍창권,노병인,허성호 ( Byung Hwan Chun,Seong Jun Seo,Chang Kwun Hong,Byung In Ro,Sung Ho Hue ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5
Sarcoidosis, a multisystemic disease of unknown cause characterized by the formation of noncaseat,ing granulomas, may involve any organ of the body. The most common sites of predilection are the lungs, lymph nodes, skin and eyes. Cutaneous sarcoidosis is seen in approximately 20-35% of patients with systcmic disease. Involvement of the central nervous system with sarcoidosis is relatively uncommon with an estimated incidence of only 3.5-5.0%. A 57-year-old male had been admitted to Department of Internal Medicine due to weight loss, polydipsia, polyuria, visual disturbance and bilateral hilar enlargement. He was diagnosed as sarcoidosis with diabetes inspidus by mediastinoscopic biopsy and a water deprivation test. On his first visit to dermatology he had several well-demarcated smooth-surfaced erythematous plaques on his forehead which had been there for 7 months. Histopathologically, many noncaseating epithelioid tubercles which are characteristic findings of sarcoidosis, were found in the dermis and subcutaneous tissue. We treated him with predniscilone 40 mg daily for 3 months and skin lesions markedly improved. (Korean J Dermatol 1997;35(5): 1013-1017)
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