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Carbon Dioxide Laser Vaporization으로 치료한 외음부의 림프관 확장증 ( 후천성 림프관종 )
남인환,허원,안성구,이승헌,강원형,김중기 ( In Whan Nam,Won Hur,Sung Ku Ahn,Seung Hun Lee,Won Hyoung Kang,Joong Gie Kim ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.6
Lymphangiectasia(acquired lymphangioma) represents acquired dilatations of lymphatics which closely resemble congenital lymphangioma clinically and his opathologically. This rare disorder may arise as a result of aquired lymphatic obstruction secondary to surgery, irradiation, chronic scar, or trauma. We present herein a case of lymphangiectasia in a 43-year-old female on a postirradiation site. She developed grouped tense oozing vesicles on the vulva, 8 years after total abdominal hysterectomy and postoperative irradiation for carcinoma of the uterine cervix. Laser therapy with the carbon doioxide laser was performed.
Q - switched Nd ; TAG 레이저를 이용한 오타 모반의 치료 효과
김중기 ( Joong Gie Kim ),김균태 ( Kyun Tae Kim ),남인환 ( In Whan Nam ),안성구 ( Sung Ku Ahn ) 대한피부과학회 1995 大韓皮膚科學會誌 Vol.33 No.4
Background : The nevus of Ota is a benign dermal melanocytic lesion that was previously proved difficult to treat. Recently, the Q-switched ruby laser and Q-switched Nd: YAG laser have been reported to by, successful in the treatment of benign pigmented lesions and tattos. Objective : Our study evaluates the treatment of 60 patients with nevus of Ota with Q-switched Nd: YAG lase (l064nm). Method : Sixty patients with nevus of Ota were treated by the Q-switched Nd: YAG laser with pulse width 10nsec, and energy fluences ranging from 5.8 to 12J/cm and the laser repetition rate was 5 or 10Hz. The response to treatment was assessed by four independent investigators with photographs. Results : 1. Total therapeutic effects of Q-switched Nd: YAG laser showed excellent result in 23.3%, good in 45%, fair in 18,3%, and poor in 13.3%. 2. Therapeutic effects by distribution proposed by Tanino showed excellent or good results in 84.6% at type Ia, 78.6% at, type Ib, 66.7% at type II, 60% at type III and 45.5% at type N. 3. Therapeutic effects by the number of treatments showed excellent or good results in 22.2% of patients after one treatment, 72.7% after two treatments, 93.3% after three treatments and 100% after four treatment. 4. Therapeutic effects by energy showed excellent or good results in 9.2% at energy range of 10 to 12J/arl and 66.6%, at energy range of 5.8-9.5J/cm. 5. Complications included transient hyperpigmentation (6.7% ), secondary bacterial infection (1.7 %), hypopigmentation (1.7%) and atrophic scar (1.7%). However these subsided spontaneously in a year. 6. The recurrence rate was 2.4%. Conclusion : The Q-switc:hed Nd: YAG laser is a very effective mode of treatment for nevus of Ota which has provent unresponsive to other therapeutic modalities. (Kor J Dermatol 1995;33(4): 686-692)
탄산가스 ( CO2 ) 레이저와 구리증기 ( copper vapor ) 레이저를 이용한 혈관 섬유종의 치료
남인환(In Whan Nam),허원(Won Hur),안성구(Sung Ku Ahn),김중기(Joong Gie Kim) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.4
Angiofibroma is a disfiguring facial deformity that constitutes pait of the multiple system involvement in tuberous sclerosis. We describe eight affected patients who have been treated with:arbon dioxide laserabration and subsequent copper vapor later treatment for residual angiomatous component, which resulted in conspicious cosmetic improvement without scarring or recurrence. This report documents that the treatment with carbon dioxide later and subsequent copper vapor laser is an efficient and safe remedy for treating multiple facial angioibromas. (Kor J Dermatol 1993;31(4):590-595)
남인환(In Whan Nam),이광훈(Kwang Hoon Lee),방동식(Dong Sik Bang),이성낙(Sung Nack Lee) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.6
Following chemotherapy and radiation treatment for infiltrating ductal carcinoma of the left breast, a 50-year-old woman presented with a child's palm sized, crusted patch and surrounding peanut sized granulated nodules on the lesion, which was diagnosed as primary cutaneous aspergillosis caused by Aspergillus fumigatus. No evidence of involvement of other organs or of systemic dissemination by Aspergillus femigatus was found. Also the patient exhibited no other apparent systemic immunologic defects. Extensive excision were performed and the patient received treatment with amphoteriein B. No evidence of recurrent fungal infection was noted during 6 months of follow-up.
남인환(In Whan Nam),김영호(Young Ho Kim),김중기(Joong Gie Kim),박장규(Jang Kyu Park) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.2
At twenty two year old female with nevus comedonicus and an increased tendency to form keloids is described. Although example of successful treatment of nevus comedonicus are readily found in the literature none propose reasonable therapeutic models for keloid formers. As our patient clearly demonstrated this tendency. We initated a t,rial with the carbon dioxide laser due to it's ability to cause less thermal damage. Subsequent to completion of this t,rial, the lesion has imprcived with the acceptable cosmetic results and less comedogenic activity. (Kor J Dermatol 1992;30(2): 221-224)
이성낙(Sung Nack Lee),한신원(Shin Won Han),방동식(Dong Sik Bang),남인환(In Whan Nam) 대한피부과학회 1984 大韓皮膚科學會誌 Vol.22 No.3
This study was undertaken to evaluate the efficacy and safety of orally administered ketoconazole in the treatment of onychomycosis. Thirteen patients with onychomycoiis were selected for this study. For evaluation of ketoconazole efficacy twelve patients received a 200 mg tablet of ketoconazole daily and one patient received a. 10() mg tablet of ketoconazole daily. All patients were studied monthly clinically and mycologically by KOH mount and culture on Sabourauds medium. The results were as follows: 1. Seven(53.8%) of thirteen cases achieved remission, marked improvement occurred in three cases(23.1%) and moderate improvement occurred in three cases (23. 1 %). 2. The mean duration of remission or clinical improvement was 5 months for all lesions and toenail lesions(5. 4 months) took longer to heal than finger nail lesions (4 months). 3. One hundred percent of patient who previously failed to respond to griseofulvin were cured or clinically improved by ketoconazole. 4. Two patients cornplained of indigestion and one of headache. In our study, ketoconazole was highly effective in the treatment of onychomycosis.
Behcet 증후군의 세포매개 면역상태에 관한 연구 - DNCB 감작율을 중심으로 -
방동식(Dong Sik Bang),이성낙(Sung Nack Lee),김덕현(Duck Hyun Kim),남인환(In Whan Nam) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.6
Various immunologic investigations of 159 patients with Behqets syndrome undertaken included; the DNCB sensitization test, total T-cells and T-cell subsets and the lymphocyte transformation test using PHA. The percentage of positive esponsiveness to DNCB decreased in the order of possible (65%), suspected (60%), incomplete (37%) and complete type (37%), The number of patients with impaired LTT was larger in the group of patients with DNCB( + ) responsiveness (seventeen of 32) than in DNCB(+) group (six of 25), There was significant impairment of cell mediated immunity in Behcets syndrome compared to normal subjects, when analyzed by the impaired LTT and decreased proportions of helper T-cells.
구리 증기 레이저 치료후 화염상 모반의 병리조직학적 소견
정준(Joon Chung),남인환(In Whan Nam),김중기(Joong Gie Kim),안성구(Sung Ku Ahn),이승헌(Seung Hun Lee) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.4
Nevus flammeus is a benign but cosmetically devascating congenital inalformation involving mature capillaries. The copper vapor laser is a therapeutic device which had been newly applied to this. Yellow copper vapor light is absorbed by the intraluminal oxyhemoglobulin mo ecules, leading to the destruction of blood vessels. This study was undertaken to evaluate the histobigic findings in a patient with nevus flammeus according to the sequential time after copper vapor laser therapy. The results were as followed, One hour after treatment, nonspecific damages to the epidermis and upper part of the dermis were observed. The specific damage to the vessels which showed thrombi formations and partial disruption of the vessel walls was prominent. One cay after treatment, degeneration of the epidermis and sepaiation of the dermoepidermal junction were apparent. Three days after treatment, extravasations of a small amount of erythrocytes and inflanimatory cell infiltrations were present, especially around the vessels. Seven days after treatment, the capillaries showed a deposition of fiorinoid material around themselves. Partial disappearance of the vessel walls was seen. There was hisi ologic evidence of the replacement of abnormal ectatic vessels by normal appearing vessels with small uminal diameters, surrounded by endothelial cells. (Kor J Dertnatol 1993;3(4):598-600)
박윤기(Yoon Kee Park),남인환(In Whan Nam) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.3
Woringer-Kolopp disease, so called pagetoid reticulosis, is most likely represent a chronic localized from of reticulosis. A 24-year old male patient visited with asymptomatic slowly enlarging, scaly single patch on his left thigh for 10 years duration. Histopathologic studies were taken with H-E stain, D-PAS, transmission electronmicroscopy and monoclonal antibody(OK6) tissue stain. Infiltration of atypical cells showed in the lower portion of epidermis like pagetoid patterned, none in dermis. It seems to be that the cell in this case probably originated from the stimuIated T-lymphocyte.
전수일(Soo Il Chun),남인환(In Whan Nam),고창조(chang Jo Koh) 대한피부과학회 1984 대한피부과학회지 Vol.22 No.5
Kaposi's sarcorna is a tumor-like condition which characterized by a mixed proliferation of fibroblastic components and vascular structures. The authors report a case of nodular type of Kaposis sarcoma in 54 year-old male who had an eroded hemorrhagic nodule and few papular lesions. These lesions involved only both hands and feet without systemic involvement.