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귀 이개에 발생한 근혈관주위세포종(Myopericytoma)
김호연 ( Ho Youn Kim ),임현정 ( Hyun Jung Lim ),박병철 ( Byung Cheol Park ),이석종 ( Seok Jong Lee ),김병수 ( Byung Soo Kim ),이원주 ( Weon Ju Lee ),김도원 ( Do Won Kim ),윤길숙 ( Ghil Suk Yoon ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.11
The concept of perivascular myomas was recently proposed to designate perivascular myoid tumors arising from pleuripotent perivascular cells like smooth muscle cell cells, pericytes and glomus cell. They represent a histological continuum between three categories; myofibromatosis, glomangiopericytoma and myopericytoma. Myopericytoma is a rare, soft tissue tumor that primarily occurs in the skin and the subcutaneous and soft tissues of the extremities, but very few cases have been reported in other locations, which occurred in our present case. We herein report on a rare case of myopericytoma that developed on an unusual location, that is, the ear. The patient was a 35-year-old man who had a painless, slowly-growing red nodule on the upper auricle of the right ear for 5 years. The nodule was revealed to be a well-circumscribed mass composed of round to oval cells that strongly expressed smooth muscle actin. These cells were arranged in the concentrically multilayered pattern and they were surrounded by small to medium-sized vessels. (Korean J Dermatol 2009;47(11):1304~1308)
켈로이드와 비대흉터에서 스테로이드, 5-fluorouracil 병변내 주사 및 색소 레이저 병용요법에 관한 비교 연구
김호연 ( Ho Youn Kim ),임현정 ( Hyun Jung Lim ),전재헌 ( Jae Hun Jun ),최윤석 ( Yoon Seok Choe ),김병수 ( Byung Soo Kim ),이원주 ( Weon Ju Lee ),이석종 ( Seok Jong Lee ),김도원 ( Do Won Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.6
Background: Despite the physical disfigurement, bothersome symptoms and psychological problemsfrom the proliferative scarring process of keloids and hypertrophic scars, there is currently no consensus regarding the best management of these lesions. Objective: The purpose of this study was to determine the therapeutic efficacy and safety of intralesional corticosteroid injection combined with 5-fluorouracil (5-FU) and/or pulsed dye laser (PDL) in Koreans with keloids or hypertrophic scars. Methods: Twenty-five patients with keloids and/or hypertrophic scars over 2 cm in size or who had more than 3 separated lesions were included in this study. Each scar was divided equally into 2 or more segments and these were treated with 1 of the following 3 different modalities: (1) intralesional injection of triamcinolone acetonide (TCA: 20 mg/ml weekly), (2) intralesional injection of TCA 0.1 ml (40 mg/ml) mixed with 5-FU 0.9 ml (50 mg/ml) weekly and (3) treatment #2 combined with PDL (585 nm, 5∼7.5 J/cm2) at baseline and at the 3rd and 7th weeks. We estimated the change of the height, the erythema, the pliability, the pruritus, the pain/tenderness scores, the patient-self assessment and the complications. This study was an 8-week prospective study and the assessment of relapse was done at 4 and 12 weeks after the last treatment. Results: There was a statistically significant improvement of the clinical signs and symptoms in all the treated groups. However, the 5-FU-treated groups had more sustained effects compared to the group that underwent TCA monotherapy with respect to flattening and pliability. Complications such as ulcerations, crusts and hyperpigmentation were more frequent in the 5-FU-treated groups. Conclusion: Although 5-FU may be preferable to TCA for improving the symptoms of keloids and hypertrophic scars, we believe it is prone to induce more complications in Koreans. (Korean J Dermatol 2009;47(6):658∼666)