안정화된 만성 정신분열병 환자에서 강박장애 동반과 사회적 기능

강석훈,석정호,김찬형,김윤중,김형주,최종혁,Kang, Suk-Hoon,Seok, Jung-Ho,Kim, Chan-Hyung,Kim, Yoon-Joong,Kim, Hyoung-Ju,Choi, Jong-Hyuck 대한불안의학회 2011 대한불안의학회지 Vol.7 No.1

Objective : This study aimed to investigate the prevalence of obsessive-compulsive disorder (OCD) in schizophrenia, and the relationship among OCD, severity of psychopathology, and social function in stable patients with chronic schizophrenia. Methods : We interviewed 138 symptom-stable inpatients who had been on a constant dose of antipsychotics for at least 1 month prior and diagnosed as chronic schizophrenia. Subsequently, patients were classified according to the existence of OCD as investigated using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I) and the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Further, all clinical and demographic data was investigated. To investigate potential interrelationships, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Korea-Positive and Negative Symptom Scale (K-PANSS), and the Korean Personal and Social Performance (K-PSP) were used. An independent ttest and Chi-square test were used to compare groups and a Pearson's correlation coefficient was used to assess the relationship between the Y-BOCS and other clinical rating scales. Results : The prevalence of OCD in schizophrenia patients was 18.1%. Patients with schizophrenia and OCD exhibited significantly earlier onset of schizophrenia, more severe psychiatric symptoms, and lower personal and social performance ability as compared to those without OCD. There was no significant relationship among Y-BOCS, K-PANSS, and K-PSP. Conclusion : We found that comorbid OCD was relatively more frequent in patients with schizophrenia. An investigation involving larger samples of schizophrenia patients with OCD with respect to social function and thus, the effect on quality of life is required.

안정화된 만성 조현병 환자에서 강박장애 증상이 삶의 질에 미치는 영향

문정윤,강석훈,석정호,김찬형,김태용,최진희,소형석,Moon, Jung Yoon,Kang, Sukhoon,Seok, Jung-Ho,Kim, Chan-Hyoung,Kim, Tae Yong,Choi, Jin Hee,So, Hyong Seok 대한불안의학회 2017 대한불안의학회지 Vol.13 No.2

Objective : This study aimed to evaluate the relationship between comorbid obsessive compulsive disorder (OCD) and quality of life in stable patients with schizophrenia. Methods : We interviewed 162 symptom-stable inpatients who have been on a constant dose of antipsychotics for at least 3 months prior and diagnosed as chronic schizophrenia. Subsequently, patients were classified according to the existence of OCD as evaluated using the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). Further, all clinical and demographic data were collected and evaluated. To investigate potential interrelationships, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Korea-Positive and Negative Symptom Scale (K-PANSS), Korean Modification of the Scale to Measure Subjective Well-Being under Neuroleptic Treatment (KmSWN) and Korean Version Quality of Life Scale (K-QOLS) were performed. Independent t-test and Chi-square test were used to compare groups and regression analysis was done to assess the relationship between the Y-BOCS and quality of life. Results : Schizophrenia patients with OCD showed significantly earlier onset of schizophrenia, more severe psychiatric symptoms and lower quality of life, compared to those without comorbid OCD. OCD might be associated with lower quality of life in schizophrenia. Conclusion : Schizophrenia patients with OCD showed lower quality of life than those without OCD. In the treatment for schizophrenia, evaluation of OCD might be needed to improve their quality of life and social function.

개인주의-집단주의 성향이 조직몰입과 혁신행동에 미치는 영향

양회창(Hoe-Chang Yang),김찬형(Chan-Hyoung Kim),조희영(Hee-Young Cho) 피터드러커 소사이어티 2020 창조와 혁신 Vol.13 No.1

본 연구는 조직 구성원들의 성향과 인지하는 고용관계특성이 조직발전을 위한 몰입 정도와 혁신행동에 미치는 영향을 확인함으로써 기업차원에서 필요한 인재 획득을 위한 정보를 제공하고 구성원들을 지원할 수 있는 방향을 모색하고자 하였다. 이를 위해 본 연구에서는 구성원의 가치성향을 개인주의와 집단주의로 구분하고 고용관계특성과 조직몰입 및 혁신행동 간에 구조화된 연구모형을 설정하였다. e-mail을 통해 회사원 141명의 유효응답을 획득하고, 회귀분석, 다중회귀분석 및 3단계 매개회귀분석을 통해 가설을 검증하였다. 분석결과 구성원들의 개인주의-집단주의 성향은 각각 고용관계특성에 긍정적인 영향을 미치는 것으로 나타났으며, 구성원들의 집단주의 성향이 고용관계특성에 더 긍정적인 영향을 미치는 것으로 확인되었다. 한편 고용관계특성은 구성원들의 성향과 조직몰입, 혁신행동 각각의 관계에서 모두 매개효과가 있는 것으로 확인되었다. 따라서 기업은 구성원들이 우리라는 개념을 획득할 수 있도록 정보 공유와 참여가 가능한 시스템을 구축하여야 하며 구성원들이 긍정적인 고용관계특성을 인지할 수 있도록 다양한 지원활동을 수행함으로써 조직몰입과 혁신행동을 향상시킬 수 있을 것이다. The purpose of this study is to find the direction to provide information and acquire the necessary talents at the corporate level by identifying the tendency of the members of the organization and the characteristics of perceived employment relationships on the level of commitment and innovation behavior for organizational development. To this end, in this study, the value inclination of members was divided into individualism and collectivism, and a structured research model was established between the sub-factors of employment relationship characteristics and organizational commitment and innovation behavior. A total of 141 effective questionnaire were obtained through e-mail, and the hypothesis was verified using regression analysis, multiple regression analysis, and 3-step regression analysis. As a result of analysis, it was confirmed that the value inclination of each member had a positive effect on the characteristics of the employment relationship. In particular, it was found that the tendency of the collectivism of the members had a more positive effect on the characteristics of the employment relationship. On the other hand, the characteristics of employment relations were found to have a mediating effect in each relationship between members tendency and organizational commitment, innovation behavior, respectively. Therefore, companies should build a system that allows information sharing and participation so that members can acquire the concept of “we”. In addition, it is necessary to improve organizational commitment and innovation through various education and support activities so that employees can recognize the positive characteristics of employment relations.

호흡 동조 구동 팬톰을 이용한 호흡패턴에 따른 4DCT, Slow-CT의 내부표적체적 변화 연구

이순성,최상현,민철기,지영훈,김미숙,유형준,김찬형,김금배,Lee, Soon Sung,Choi, Sang Hyoun,Min, Chul Kee,Ji, Young Hoon,Kim, Mi-Sook,Yoo, Hyoung Jun,Kim, Chan Hyeong,Kim, Kum Bae 한국의학물리학회 2014 의학물리 Vol.25 No.1

본 연구에서는 호흡 동조 구동 팬톰을 이용하여 5가지의 호흡패턴에 따른 4DCT와 Slow-CT의 내부표적체적(ITV) 변화를 비교 분석하였다. 각 호흡패턴마다 호흡주기 1~4초와 표적 진폭 1~3 cm를 적용하여 4DCT와 Slow-CT를 각 3회 촬영하였다. 촬영한 영상들은 Eclipse 치료계획 시스템으로 표적을 윤곽 묘사하고 내부표적체적(ITV) 길이와 체적을 측정하였으며, 4DCT, Slow-CT의 ITV 길이와 체적의 평균값을 이론값과 비교하여 분석하였다. 4DCT에서의 ITV 길이와 체적은 호흡주기가 길수록, 표적 진폭이 짧을수록 이론값과의 차이가 감소하는 경향을 보였다. Slow-CT에서는 표적 진폭이 커질수록 4DCT와 마찬가지로 이론값과의 차이가 커졌으나 호흡주기에 따른 ITV 길이와 체적의 변화는 호흡주기 1초에서 가장 이론값 비슷하였고 2~4초 내에서는 재현성의 변화가 근소했다. 호흡패턴에 따라서는 4DCT, Slow-CT 모두 ITV 길이와 체적에 대해 A패턴에서 가장 높은 재현성을 보였고, B, C, D패턴은 서로 비슷한 차이를 보였으며 E패턴은 다른 네 패턴에 비해 이론값과의 차이가 가장 컸다. 4DCT에 대한 Slow-CT의 ITV 길이와 체적의 차이는 모든 호흡패턴에 대하여 호흡주기가 길수록, 표적 진폭이 클수록 증가하였다. 4DCT와 Slow-CT 영상간의 ITV 길이 및 체적에 대한 재현성을 비교했을 때 Slow-CT가 4DCT에 비해 평균적으로 약 22% 낮았으며, 호흡패턴에 따라 상, 하 방향에 대해 표적의 재현성이 달라졌다. A, B, C패턴의 경우 상, 하 방향으로 3 mm, E패턴은 상 방향에 비해 하 방향에서 5 mm의 차이를 보인 반면에 D패턴에서는 상 방향으로는 차이가 없었으나 하 방향으로 1.45 cm의 차이가 났다. 따라서 4DCT에 대하여 Slow-CT에 표적 움직임을 고려한 여유를 설정할 경우에는 호흡패턴에 따라 상, 하 방향에 다른 여유를 정의해야 한다고 판단된다. 향후 환자의 호흡신호를 바탕으로 CT 영상을 분석할 때 본 연구에서 수행한 데이터가 유용하게 사용될 것으로 사료된다. The objective of this study is to investigate the difference of ITV lengths and ITVs between 4DCT and Slow-CT images according to respiratory patterns using a respiratory motion phantom. The respiratory periods 1~4 s and target motion 1~3 cm were applied on each respiratory pattern. 4DCT and Slow-CT images were acquired for 3 times. 4DCT and Slow-CT ITVs were measured with contouring the target in the Eclipse RTP system. The measured ITV lenghts and ITVs in 4DCT and Slow-CT images were compared to the known values. For the ITV lengths and ITVs in the 4DCT, the difference of them were reduced as the respiratory period is longer and target motion is shorter. For the Slow-CT, there was same tendency with change in 4DCT ITV lengths and ITVs about target motion. However, the difference of ITV lengths and ITVs for the respiratory periods were the lowest in respiratory period 1 second and different slightly within respiratory period 2-4 seconds. According to the respiratory patterns, pattern A had the highest reproducibility. Pattern B, C and D were showed the difference similar to each other. However, for pattern E, the reproducibility was the lowest compared with other four patterns. The difference of ITV lengths and ITVs between Slow-CT and 4DCT was increased by increasing the respiratory periods and target motion for all respiratory patterns. When the difference of Slow-CT ITV lengths and ITVs were compared with that of 4DCT ITV lengths and ITVs, Slow-CT ITV lengths and ITVs were approximately 22 % smaller than 4DCT, and the representations of target were different in each pattern. In case of pattern A, B and C, length difference was 3 mm at S (superior) and I (inferior) direction, and the length difference of pattern D was 1.45 cm at only "I" direction whereas the length difference of pattern E was 5 mm longer in "S" direction than "I" direction. Therefore, the margin in SI directions should be determined by considering the respiratory patterns when the margin of Slow-CT is compensated for 4DCT ITV lengths. Afterward, we think that the result of this study will be useful to analyze the ITV lengths and ITVs from the CT images on the basis of the patient respiratory signals.