부선(浮選) 광미(鑛尾)의 순환자원화(循環資源化)를 위한 비소성(非燒成) 토건재료(土建材料) 개발(開發)

김주익,정문영,박제현,이진수,Kim, Joo-Ik,Jung, Moon-Young,Park, Jay-Hyun,Lee, Jin-Soo 한국자원리싸이클링학회 2011 資源 리싸이클링 Vol.20 No.1

부선 광미의 근원적 처리방안으로 경제성과 환경친화성을 고려히여 비소성 토건재료로 순환자원화 하는 연구를 수행하였다. 순신광산 광미의 평균입도는 $220\;{\mu}m$이고 삼광광산 광미의 평균입도는 $140\;{\mu}m$이었다. 따라서 이들 광미의 입도 특성을 고려하여 순신광산 광미는 비소성 투수블록의 원료 그리고 삼광광산 광미는 비소성 에코벽돌의 원료로 사용하여 제조한 시험체의 여러 특성을 조사하였다. 순신광산 광미 25 wt%이하의 배합조건에서 제조한 비소성 투수블록 시험체의 압축강도는 한국환경산업기술원(KEITI)에서 제시하고 있는 투수콘크리트 제품 규격(EL 245)인 14.70MPa 이상을 만족하였다. 그러나 투수계수 측정결과, 투수콘크리트 제품 규격(EL 245)인 $1.0{\times}10^{-2}\;cm/sec$ 이상을 만족하지 못하였다. 한편, 삼광광산 광미 40 wt% 이하의 배합조건에서 제조한 비소성 에코벽돌 시험체는 소성점토벽돌(KS L 4201) 3종 규격을 만족하였다. 또한 중금속용출시험(KSLT) 결과, 비소성 에코벽돌 시험체의 환경안정성이 확인되었다. This study was conducted to recycle flotation tailings as non-sintered construction materials considering the economic and eco-friendly treatments. The particle size distribution( median $220\;{\mu}m$) of flotation tailings from Soon-shin mine was confirmed to be larger than that(median $140\;{\mu}m$) of tailings from Sam-kwang mine. Thus we investigated the properties of non-sintered eco-brick producted with the tailings from Sam-kwang mine and non-sintered water permeable block producted with the tailings from Soon-shin mine. Compressive strength of non-sintered water permeable block which was made with less than 25 wt% of tailings from Soon-shin mine was met with products class(over 14.70 MPa) of water permeable concrete(EL 245) from KEITL. Meanwhile, the coefficient of its permeability wasn't met with the products class( over $1.0{\times}10^{-2}\;cm/sec$). The properties of non-sintered eco-brick with less than 40 wt% of tailings from Sam-kwang mine were satisfied with third class in sintered clay brick products standard(KS L 4201). The non-sintered eco-brick as a result of leaching test on heavy metals by KSLT was verified to be environmentally stabile.

잔물결모양 피지선상피종

김주익 ( Joo Ik Kim ),우수한 ( Soo Han Woo ),김대우 ( Dae Woo Kim ),황수란 ( Su Ran Hwang ),이진호 ( Chin Ho Rhee ),박진 ( Jin Park ),김한욱 ( Han Uk Kim ),윤석권 ( Seok Kweon Yun ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.12

Rippled-pattern sebaceoma, a very rare histologic variant of sebaceoma, manifests as a peculiar arrangement of basaloid cells in linear and parallel rows, resembling Verocay bodies. It represents dermal aggregations composed of small, monomorphous, basaloid, sebaceous germinative cells. It has a tendency to occur in men, with the scalp as the predilection site. To our knowledge, only one case has been reported to date in the Korean dermatologic literature. Here, we report a case of rippled-pattern sebaceoma that appeared as a flesh nodule on the occiput and had been present for 4 years in a 41-year-old man. (Korean J Dermatol 2014;52(12):900∼902)

보중익기탕의 랫트 단회 경구투여 독성실험

김주익 ( Joo-ik Kim ),송창현 ( Chang-hyun Song ),박수진 ( Soo-jin Park ),최성훈 ( Seong-hun Choi ),구세광 ( Sae-kwang Ku ) 대구한의대학교 제한동의학술원 2021 제한동의학술원논문집 Vol.19 No.1

Objectives : The objective of this study was to obtain acute (single) oral dose toxicity information of Bojungikki-tang (BJIKT), prepared and standardized by Aribio Ltd. (Seungnam, Korea), in female and male Sprague-Dawley rats as a process to develop of natural origin medicinal ingredient or food itself. Materials and methods : In order to investigate the toxicity and identify target organs, BJIKT were once orally administered to female and male Sprague-Dawley rats at dose levels of 2000, 1000, 500 and 0 (vehicle control) mg/kg (body weights) in a volume of 10 ml/kg, dissolved in distilled water, and the mortality and changes on the body weight and clinical signs were monitored during 14 days after treatment with gross observation, changes on the organ weights and histopathology of principle organs based on the recommendation of Organization for Economic Co-Operation and Development (OECD) Guideline 423 based Korea Food and Drug Administration (KFDA) Guideline (2015-082, 2015), as compared with those of equal genders of vehicle control rats. Because there are no available toxicological data after oral treatment in female and male rats of BJIKT, the highest dosage used in the present study were selected as 2,000 mg/kg in a volume of 10 ml of distilled water - the limited dosages of rodents, and 1,000 and 500 mg/kg were selected as middle and lower dosage groups according to OECD Guideline 423 based KFDA Guidelines (Notification No. 2015-082, 2015). In addition each female and male vehicle controls were added in this experiment. Principal organs for weighing : Lung, Heart, Thymus, Liver, Left Kidney, Left Adrenal Gland, Spleen, Left Testis/Ovary, Splenic lobe of Pancreas, Brain, Urinary bladder, Left Epididymis/total Uterus, Prostate and Left Submandibular Lymph node [Total 16 organs] Specific target organs for histopathology : Brain (Cerebrum, Cerebellum and Medulla oblongata), Heart, Thymus, Lung, Testis, Epididymis (head parts), Uterus, Ovary, Left-kidney, Left-adrenal glands, Spleen, Liver-left lateral lobe, Pancreas-splenic part, Digestive tracts (Esophagus, Fundus, Pylorus, Duodenum, Jejunum, Ileum, Cecum, Colon and Rectum), Left-submandibular lymph nodes, Urinary bladder and Prostate [Total 27 organs]. Results : As the results of single oral treatment of BJIKT on the female and male Sprague-Dawley rats, no treatment related mortalities were observed within 14 days after end of treatment up to 2,000 mg/kg, the limited dosage of rodents in the both genders, and also no BJIKT treatment related changes on the body and organ weights, clinical signs, necropsy and histopathological findings were detected, in this experiment. Conclusion : The results obtained in this study suggest that the BJIKT, prepared and standardized by Aribio Ltd. (Seungnam, Korea), is non-toxic in rats and is therefore, likely to be safe for clinical use. The 50% lethal dose (LD50) and approximate LD in rats after single oral dose of BJIKT were considered over 2,000 mg/kg, the limited dosage of rodents in both female and male Sprague-Dawley rats, respectively. In addition, no specific target or clinical sings were detected in the present study.

여드름에 의한 Solid Facial Edema

송기훈 ( Ki Hun Song ),김주익 ( Joo Ik Kim ),남경화 ( Kyung Hwa Nam ),박진 ( Jin Park ),윤석권 ( Seok Kweon Yun ),김한욱 ( Han Uk Kim ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.10

Solid facial edema is a rare skin condition characterized by persistent, non-pitting, and non-tender edema on the forehead, glabellar region, mid-face, nasolabial folds, and cheeks. Exact etiology is still unknown; however, it is suggested that it can be secondary inflammatory response due to acne vulgaris. A 21-year-old male presented with erythematous swollen patches on the forehead and glabellar region. He had been intermittently treated for his acne vulgaris for 5 years at the local clinic. Focal soft tissue swelling with thickening of the skin and subcutaneous tissue was identified radiologically. Histopathologically, lymphatic vessels were dilated with chronic inflammatory cell infiltration and dermal edema. To the best of our knowledge, this is the first reported case of solid facial edema caused by acne vulgaris in Korea.

악성 단순 한선 극세포종

김대우 ( Dae Woo Kim ),우수한 ( Soo Han Woo ),김주익 ( Joo Ik Kim ),황수란 ( Su Ran Hwang ),이진호 ( Chin Ho Rhee ),박진 ( Jin Park ),윤석권 ( Seok Kweon Yun ),김한욱 ( Han Uk Kim ) 대한피부과학회 2015 대한피부과학회지 Vol.53 No.3

Malignant transformation of hidroacanthoma simplex into in situ porocarcinoma, also known as hidroacanthoma simplex with invasive growth, is very rare. Malignant hidroacanthoma simplex generally arises in the elderly and occurs most frequently on the lower extremities and trunk. The gross appearance of the tumor tends to vary, and there are nodular lesions or keratotic plaques with or without erosion and/or ulceration. In some cases, it clinically resembles Bowen`s disease or seborrheic keratosis. Histopathologically, the tumor appears similar to hidroacanthoma simplex, but the cells are atypical with hyperchromatic nuclei, and many are in mitosis. Here we report an extremely rare case of malignant hidroacanthoma simplex that occurred on the right knee of an 84-year-old Korean woman. (Korean J Dermatol 2015;53(3):226∼229)