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      • SCIESCOPUSKCI등재
      • SCIESCOPUSKCI등재

        당뇨환자의 치은조직내 Superoxide Dismutase와 Catalase의 활성도에 관한 실험적 연구

        김병옥,이강진,박주철,Kim, Byung-Ok,Lee, Kang-Jin,Park, Joo-Cheol 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.3

        Oxygen derived radicals($O_2\;^-$, $H_2O_2$, and $OH^-$) are thought to play a role in a lot of human diseases. And it has been believed that antioxidant enzymes such as superoxide dismutase(SOD) and catalase could protect the tissues from damage resulting from the oxygen derived free radicals. The purpose of this study was performed to investigate the activity of the SOD(CuZn- and Mn-SOD) and catalase in inflammatory gingival tissues and the correlation between boold glucose level and antioxidants and age in non-insulin dependent diabetes mellitus(NI- DDM) patients. For this study, the patients were classified into normal, inflammatory, and diabetic, and ten their papillary bleeding index(PBI) and gingival index were checked. Subjects consisted of 11 healthy patients with no inflammatroy gingiva, 20 adult periodontitis patients, and 8 diabetic patients, aged 33 to 66(average: 44.62). The blood glucose level of diabetic group was ranged from 120ml/dl to 160ml/dl(physical status 0 : averge : 135.67ml/dl). Gingival tissues were surgically obtained from the patients during periodontal surgery, extraction, and clinical corwn lenghening procedure. The activity of CuZn and Mn- SOD and catalase in the gingival tissues was measured by using UV-spectrophotometer by the same methods that Crapo et al. And Aebi did, respectively. The results were as follows : 1. The Mn-SOD activity was significantly lower in inflammatory group in comparison to normal group(P<0.05), and the activities of antioxidants in diabetic group were not significant in comparison to normal inflammatory group(P>0.05). 2. The activities of antioxidants showed little variation among individuals of different ages (P>0.05). 3. The higher blood glucose level was, the higher gingival index was(P<0.05). 4. There was no correlation between blood glucoe level and activity of antioxidant in inflammatory gingival tissues of NIDDM patients(P>0.05). In conclusion, these results, within the limits of the present experiment, suggest that the activity of Mn-SOD might reflect the inflammatory status of gingival tissue, and the activity of antioxidants was independent of blood glucose level of diabetic patients in physical status 0.

      • SCIESCOPUSKCI등재

        치주질환 심도에 따른 치은조직내의 Superoxide Dismutase와 Catalase의 활성변화에 관한 연구

        김병옥,권영혁,이만섭,Kim, Byung-Ok,Kwon, Young-Hyuk,Lee, Man-Sup 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.1

        It has been believed that antioxidant enzymes such as CuZn- and Mn-superoxide dismutase and catalase protect the tissue from damage resulting from the oxygen derived free radicals($O_2\;^-$, $H_2O_2$ and OH ). The purpose of this study was to investigate the relationship between activity of antioxidant enzymes including CuZn- and Mn- superoxide dismutase and catalase and inflammatory periodontal disease and periodontal parameters. For this study, the patients were classified into normal, gingivitis, adult periodontitis and rapidly progressive periodontitis, and then their papillary bleeding index(PBI) and probing depth were checked. Gingival tissues were surgically obtained from the patients during periodontal surgery, extraction, and clinical crown lengthening procedure. The activity of CuZn- and Mn- superoxide dismutase and catalase in the gingival tissues was measured by using UV-spectrophotometer by the same methods as Crapo et al. And Aebi did, respectively. The results were as follows : 1. CuZn- and Mn- and total-superoxide dismutase activity were significantly low in rapidly progressive periodontitis group in comparison to normal group (P<0.05). 2. In comparison of the antioxidant enzyme activity according to papillary bleeding index group(PBI), Mn-superoxide dismutase activity only was significantly lower in PBI 2, 3, and 4 groups than PBI 0 group(P<0.05). 3. Superoxide dismutase activity failed to show any significant difference according to probing depth. But significant]y high catalase activity was shown in deep pocket group (${\ge}7mm$)(P<0.05). In conclusion, these results suggest that the activity of Mn-superoxide dismutase among the antioxidant enzymes may reflect the inflammatory status of gingival tissue and that the decreased activity of superoxide dismutase may be one of responsibe factors for progression of rapidly progressive periodontitis.

      • KCI등재

        GMDSS 조난통신 제도의 문제점과 개선 방안

        김병옥,KIM Byung-Ok 한국정보통신학회 2005 한국정보통신학회논문지 Vol.9 No.4

        1992년 새로 도입된 GMDSS(Global Maritime Distress and Safety System: 세계 해상 조난 및 안전 제도)는 기존의 조난통신 제도를 새로운 정보통신기술을 사용하여 획기적으로 개선하였으며 쉽고 자동화된 조난신호발신 체제 및 효율적이고 범세계적인 수색구조 통신망을 구축하였음에도 불구하고 여러 가지 문제점을 나타내고 있다. 협약선과 비협약선의 조난통신 이원화 문제, 다량의 허위 조난신호 발생에 따른 수색구조의 어려움, 운용능력의 저하로 인한 조난통신 대응체제의 부재 둥은 GMDSS 제도의 도입에 따른 조난통신의 대표적인 문제점들이다 본 논문에서는 우리나라의 관점에서 본 GMDSS 조난통신 제도의 문제점 들을 분석하고 이에 대한 개선방안을 제시하고자 한다. The distress communication system in the maritime mobile service had almost depended on the wireless telephony or telegraphy technique. The GMDSS (Global Maritime Distress and Safety System) which was introduced in 1992 brought a lot of changes in the maritime distress communication service such as the automatic transmission of distress signals and implementation of global search and rescue networks. However, there are some deficiencies in the GMDSS distress communication system such as a lack of compatibility in the maritime distress communication between CMDSS ships and Non-GMDSS ships, increasing deceptive or false distress alerts generated by GMDSS installations, lack of understanding about the CMDSS installations for the operators. In this paper, the problems of distress communication system in the maritime mobile service are analyzed and the methods to solve or minimize these problems are suggested.

      • SCIESCOPUSKCI등재

        치주질환 환자의 말초혈액내 glutathione peroxidase와 catalase의 활성 변화에 관한 연구

        김병옥,김찬진,한경윤,Kim, Byung-Ok,Kim, Chan-Jin,Han, Kyung-Yoon 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.3

        It has been believed that the increased release of free oxygen radicals ($O_2^-,H_2O_2$, and $OH^-$) might be a factor in the pathogenesis of periodontal diseases. Antioxidant enzymes such as glutathione peroxidase(GSH-PX) and catalase can protect the tissue damage from the $H_2O_2$. In order to investigate the GSH-PX and catalase activity in the blood plasma and red blood cells(RBCs) of the patients with periodontitis, 19 patients who had good general health, attachment loss more than 6 mm and bone loss were selected as periodontitis group, 7 patients who had severely inflamed gingiva were selected as gingivitis group, and 15 volunteers with good general and periodontal health were selected as normal group. 17 of 26 patients were performed scaling and root planing to reduce the gingival inflammation for gingivitis and periodontitis groups, and were selected as posttreatment group. After blood plasma and RBCs were collected and separated 1 ml of peripheral blood from each subject, GSH-PX activity in blood plasma and RBCs was measured by the same method that Stefan et al. did, and catalase activity in RBCs was measured by the same method that Beers et al. did. The difference of GSH-PX and catalase activity between normal, gingivitis, and periodontitis groups was statistically analyzed by ANOVA with SPSS/PC+ program, and the difference between pretreatment and posttreatment groups was analyzed by Student t-test. The results were as follows : 1. GSH-PX activity in blood plasma was significantly lower in the gingivitis group($0.8683{\pm}0.0658$), periodontitis group($0.7130{\pm}0.1333$) than in the normal group($1.0241{\pm}0.0801$)(p<0.05), and GSH-PX activity in RBCs was significantly lower in the gingivitis groupt. $0.8156{\pm}0.1167$), periodontitis group($0.7533{\pm}0.1185$) than in the normal group($l.1963{\pm}0.2044$)(P<0.05), but there was no statistical significance in the difference of GSH-PX activity in RBCs between the gingivitis group and periodontitis group(p>0.05). 2. Catalase activity in RBCs was siginficantly lower in the periodontitis group($117.34{\pm}35.01$) than in the normal group($l52.38{\pm}32.09$)(p<0.05). 3. GSH-PX activity in blood plasma was significantly increased in the posttreatment groupe $1.0376{\pm}0.2820$) compared to the pretreatment group(0.7608 0.1600) (p<0.05), and GSH-PX activity in RBC was significantly increased in the posttreatment group($1.0421{\pm}0.2330$) compared to the pretreatment group($0.7728{\pm}0.1210$)(p<0.05). 4. There was no statistical significance in the difference of catalase activity in RBCs between the pretreatment group($112.04{\pm}43.65$) and posttreatment group($l33.41{\pm}39.16$)(p>0.05).The results, within the limits of the present experiment, suggest that the lowered activity of GSH-PX and catalase in blood plasma and RBCs may be related with periodontopathogenesis.

      • KCI등재

        터보차져의 로터다이나믹 해석모델 개발 및 진동응답 해석

        김병옥(Byung Ok Kim),이안성(An Sung Lee) 한국유체기계학회 2010 한국유체기계학회 논문집 Vol.13 No.5

        This paper deals with the development of analytical model of a turbocharger and its detail rotordynamic analysis. Two analytical models, which are verified by experimental modal testing, are proposed and the analytical model including rotor shaft extended to compressor and turbine wheel end side is chosen. A rotordynamic analysis includes the critical map, Campbell diagram, stability, and unbalance response, especially nonlinear transient response considering nonlinear fluid film force at bearings. Although the linearized analysis accurately predicts the critical speeds, stability limit, and stability threshold speed, the predicted vibration results are not valid for speeds above the stability threshold speed since the rotor vibrates with a subsynchronous component much larger than the one synchronous with rotor speed. Hence, for operating speed above the stability threshold, a nonlinear transient analysis considering nonlinear fluid film force must be performed in order to accurately predict vibration responses of rotor and guarantee results of analysis.

      • KCI등재

        산소공장 공기터보압축기(ATC)의 회전체동역학 설계특성 분석 및 진동저감

        김병옥(Byung Ok Kim),이안성(An Sung Lee) 한국유체기계학회 2010 한국유체기계학회 논문집 Vol.13 No.3

        In this study rotordynamic characteristics of an air turbo-compressor (ATC) used in oxygen plant are analyzed and its operating-speed balancing is performed to solve the vibration trouble caused by rotor unbalance. Three dimensional model of the ATC rotor is completed and then analytical FE (finite element) model, which is verified by experimental modal testing, is developed. A rotordynamic analysis includes the critical map, Campbell diagram, and unbalance response, especially considering the pedestal housings supporting tilting pad bearings. A test run of operating-speed, using tilting-pad bearing of actual use, showed that the vibration level increased very sharply as approaching the rated speed. The operating-speed balancing specified by API 684 was carried out by using influence coefficient method. The results showed that the vibrations at the bearing pedestal housings represented good levels of 0.1 ㎜/s. From the test run and operating-speed balancing, the analytical results, that is, critical speeds are in good agreement with the test results and unbalance responses introducing the correction masses are similar to the as-is test responses in its aspect.

      • KCI등재
      • KCI등재

        API 610 BB5 펌프 개발을 위한 로터다이나믹 특성분석

        김병옥(Byung Ok Kim),이안성(An Sung Lee),김성기(Sung Ki Kim) 한국유체기계학회 2011 한국유체기계학회 논문집 Vol.14 No.4

        This paper deals with the detail rotordynamic analysis for BB5 eight stages pump as development of API 610 BB5 type pump. Dry-run analytical model, not considering operating fluid, and wet-run analytical model, considering operating fluid are established. In addition, plain circular and pressure dam bearings are chosen and it was discussed that each bearing has an effect on dynamic characteristics of pump rotor system. A rotordynamic analysis includes the critical speed map, Campbell diagram, stability, and unbalance response. As results, it was predicted that rated speed of the pump rotor passes through 1st critical speed in dry-run condition regardless of bearings, however, it was verified that, in wet-run condition, the rotor system doesn’t have critical speeds even if more than twice rated speed. Hence the resonance problem caused by the critical speeds does not happen since actual operating is in wet-run condition including operating fluid. As a result of unbalance response analysis, the pump rotor has stable vibration response at rated speed, regardless of operating fluid and the proposed bearing types.

      • KCI등재

        터보차져용 터빈의 스핀 테스트를 위한 로터다이나믹 특성분석

        김병옥(Byung Ok Kim),양성진(Sung Jin Yang),이명호(Myung Ho Lee) 한국유체기계학회 2011 한국유체기계학회 논문집 Vol.14 No.6

        This paper deals with the detail rotordynamic analysis for the assembly rotor composed of turbine wheel, turbine shaft, connecting arbor, and flange & spindle in order to perform the spin test of turbocharger turbine. Prior to rotordynamic analysis, the 1st spin test was performed but the test was failed by excess vibration in the neighborhood rated speed. It is the reason for this fail that the separation margin between the rated speed and critical speed is not enough, confirmed by rotordynamic analysis results. Since then, the dimension of turbine shaft was modified and the critical speeds were again reviewed for modified assmebly rotor. In results, the separation margin between the rated speed and critical speed is over 20% and then the 2nd spin test was performed successfully. In preparing spin test for turbine, compressor wheels and etc., the geometry design of connecting arbor and dimension of rough machining should be reviewed by considering rotordynamic results, and the separation margin should be enough for successful spin test.

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