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      • KCI등재

        Comparison of Human Muscle-Derived Stem Cells and Human Adipose-Derived Stem Cells in Neurogenic Trans-Differentiation

        권은비,이지영,박수옥,김인걸,라정찬,이지열 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.12

        Purpose: Erectile dysfunction (ED) remains a major complication from cavernous nerve injury during radical prostatectomy. Recently, stem cell treatment for ED has been widely reported. This study was conducted to investigate the availability, differentiation into functional cells, and potential of human muscle-derived stem cells (hMDSCs) and human adipose-derived stem cells (hADSCs) for ED treatment. Materials and Methods: We compared the neural differentiation of hMDSCs and hADSCs. Human muscle and adipose tissues were digested with collagenase, followed by filtering and centrifugation. For neural induction, isolated hMDSCs and hADSCs were incubated in neurobasal media containing forskolin, laminin, basic-fibroblast growth factor, and epidermal growth factor for 5 days. Following neural induction, hMDSCs and hADSCs were differentiated into neural cells, including neurons and glia, in vitro. Results: In neural differentiated hMDSCs (d-hMDSCs) and differentiated hADSCs (d-hADSCs), neural stem cell marker (nestin) showed a significant decrease by immunocytochemistry, and neuronal marker (b-tubulin III) and glial marker (GFAP) showed a significant increase, compared with primary hMDSCs and hADSCs. Real-time chain reaction analysis and Western blotting demonstrated significantly elevated levels of mRNA and protein of b-tubulin III and GFAP in d-hADSCs compared with d-hMDSCs. Conclusions: We demonstrated that hMDSCs and hADSCs can be induced to undergo phenotypic and molecular changes consistent with neurons. The neural differentiation capacity of hADSCs was better than that of hMDSCs.

      • KCI등재

        The Effect of an L2 Motivational Program for New Junior College English Major Students: Focusing on How the Learners Changed

        권은비 한국영어교육학회 2022 ENGLISH TEACHING(영어교육) Vol.77 No.4

        This paper explores the L2 motivation of 11 students about to start studying English as junior college English majors. The participants took part in a ten-day L2 motivational program designed to help them with L2 skills and life on campus. To understand how they participated in the program, data gathered from online learning logs were coded using qualitative thematic analysis. Consequently, the participants shifted to embody ‘none to something’ qualities in terms of L2 selves and effort during the program. That is, they established self-images to believe in when using and learning English, which eventually developed into effort-driven attitudes and behavior. The students also set goals and plans according to their L2 selves created or revealed during the program. Although the program was comparatively short with a small number of participants entering a junior college, the findings indicate that an L2 motivational program for new adult students could be conducive to promoting and sustaining their effort, L2 selves, and motivation.

      • KCI등재
      • KCI등재

        마을주민과의 관계가 농촌 단독가구 노인의 행복감에 미치는 영향

        권은비(Kwon, Eun-Bi),이정화(Lee, Jeong-Hwa) 한국지역사회복지학회 2012 한국지역사회복지학 Vol.0 No.42

        본 연구는 마을주민과의 관계가 농촌 단독가구 노인의 행복감에 미치는 영향을 노인의 성과 배우자유무를 중심으로 살펴보았다. 본 연구는 총 443명의 농촌 단독가구 노인을 대상으로, 성과 배우자유무에 따라 이들의 마을주민과의 양적이고 질적인 관계가 차이가 나는지 살펴보았고, 마을주민과의 관계가 이들의 행복감에 미치는 영향이 단독가구 노인의 성과 배우자유무에 따라 차이가 나는지 파악하였다. 연구결과, 마을주민과의 관계는 농촌 단독가구 노인의 행복감에 영향을 주는 변인인 것으로 나타났다. 남성의 경우 마을주민과의 관계의 양적인 측면인 ‘교류정도’가, 여성의 경우 질적인 측면인 ‘정서적 친밀감’이 행복감에 미치는 영향이 큰 변수로 나타났다. 배우자가 있는 경우에는 마을주민과의 관계의 질적인 측면이, 배우자가 없는 경우에는 관계의 양적인 측면과 질적인 측면 모두가 행복감에 영향을 주는 변인인 것으로 나타나 배우자 없이 지내는 독거노인에 대한 마을주민과의 관계의 중요성을 확인할 수 있었다. 이러한 분석에 기초하여 농촌 단독가구 노인을 위한 정책적 함의가 논의되었다. This study examines the effect of neighboring relations on the happiness of the rural elderly-only households. Especially, focused on the effect of gender and marital status of the elderly. neighboring relations include both ‘degree of exchange with neighbors" and ‘emotional intimacy between neighbors". For the purpose of this research, 443 participants, who are older than 65 years old, live in rural areas, were selected. The results of this study are summarized as follows: First, while the ‘degree of exchange with neighbors" is more important for the males, the ‘emotional intimacy between neighbors" is more important for the females in terms of happiness. Second, the ‘emotional intimacy between neighbors" has a greater effect on the happiness of the groups living with a spouse than the other groups. However, both the ‘degree of exchange with neighbors" and the ‘emotional intimacy between neighbors" are important for the happiness of elderly people living alone. On the basis of this analysis, policy implications regarding rural elderly single and couple households were discussed.

      • KCI등재

        은퇴한 남성의 생활만족도에 영향을 미치는 변인 연구: 은퇴관련변인과 부부관계의 질을 중심으로

        권은비 ( Eun Bi Kwon ),이정화 ( Jeong Hwa Lee ) 한국가족관계학회 2011 한국가족관계학회지 Vol.15 No.4

        The purpose of this research was to analyze the determinants of life satisfaction in male retirees with a special focus on the role of retirement-related variables and marital quality. It also aims to find out the relative influence of variables related to male retirees` life satisfaction. To achieve these goals 375 subjects who have spouses and are retired were analyzed and the results are as follows. First, as a result of an analysis of the retirees` socio-demographic variables, there are differences in life satisfaction depending on educational level, residence type, children`s education, subjective health perception and monthly income. As for general life satisfaction, preparation for retirement, job status prior to retirement, job satisfaction prior to retirement and reason for retirement were significant predictors among the retirement-related variables. In terms of life satisfaction based on marital quality, the group with higher quality marital relationships also had a higher levels of satisfaction. Second, a hierarchical regression analysis was conducted to find out the relative influence of variables related to life satisfaction. It was found out that the variables affecting general life satisfaction are subjective health perception, preparation for retirement, monthly income, level of education, children`s education, residence type and the quality of marital relationships. This study was successful in finding out the relative influence of variables especially, the influence of marital quality on life satisfaction in male retirees.

      • KCI우수등재

        초등학생의 우울과 집단따돌림 피해 및 가해행동의 관계: 인터넷 중독성향과 역기능적 분노표현의 매개효과

        권은비(Kwon, Eun-Bi),이동훈(Lee, Dong-Hun) 한국교육학회 2020 敎育學硏究 Vol.58 No.1

        본 연구는 초등학생의 우울과 집단따돌림 피해 및 가해행동의 관계에서 인터넷 중독성향과 역기능적 분노표현이 매개하는지 살펴보았다. 본 연구를 위하여 B지역 20개 초등학교의 4, 5, 6학년 651명을 대상으로 수집된 데이터가 분석에 사용되었다. 초등학생의 우울, 인터넷 중독성향, 역기능적 분노표현, 집단따돌림 피해 및 가해행동의 관계를 확인하기 위해 상관분석을 실시하였고, 인터넷 중독성향과 역기능적 분노표현이 아동의 우울과 집단따돌림 경험의 관계에서 매개하는지 확인하기 위해 구조방정식을 사용하여 매개모형 검증을 실시하였다. 연구결과 첫째, 아동의 우울은 집단따돌림 피해에직접적인 영향을 미치는 것으로 확인되었다. 둘째, 우울은 인터넷 중독성향을 매개하여 집단따돌림가해행동에 유의한 영향을 미치는 것으로 확인되었다. 셋째, 우울은 역기능적 분노표현을 매개하여집단따돌림 피해 및 가해행동에 모두 영향을 미치는 것으로 나타났다. 넷째, 우울과 집단따돌림 피해및 가해행동의 관계에서 인터넷 중독성향과 역기능적 분노표현의 이중매개효과가 유의하게 나타났다. 끝으로 본 연구의 시사점과 한계점에 대하여 논의하였다. This study examined whether internet addiction and dysfunctional anger expression mediate the relationship between Depression and Victimization and Bullying in Elementary students. For this study, Data collected on 651 students in 4th, 5th and 6th grade from 20 elementary schools in B area were used in the analysis. Correlation analysis was conducted to find out the relationship between depression, internet addiction, dysfunctional anger expression, victimization and bullying. To find out if Internet addiction and dysfunctional anger expression are mediated by the relationship between child s depression and victimization/bullying experience, the model was tested using a structural equation. The results were as follows. First, Depression has been confirmed to have a direct effect on the Victimization. Second, depression has been shown to affect the bullying by mediating Internet addiction. Third, depression has been shown to affect both victimization/bullying by mediating the dysfunctional anger expression. Fourth, the dual mediating effects of Internet addiction and dysfunctional anger expression were significant in relation to the relationship between depression and victimization/bullying. Finally, limitations and implications of this study were discussed.

      • KCI등재

        FGI를 활용한 조모의 손자녀 양육지원 의사결정 유형화 연구

        권은비 ( Eun Bi Kwon ),이정화 ( Jeong Hwa Lee ),김선미 ( Seon Mi Kim ) 한국가족복지학회 2015 한국가족복지학 Vol.20 No.4

        The purpose of this study was to understand grandmothers’ childcare support patterns by conducting a focus group interview. The data for this study came from 20 grandmothers in transition of 5 focus groups (each consisting of 4 persons) interviews. Nine of them were pre-grandmothers who did not yet have any grandchildren, and 11 were grandmothers who had grandchildren. The patterns of the grandmothers`` intentions of supporting childcare were classified. The patterns were categorized by the grandmothers`` intentions of providing childcare support for their grandchildren according to the participants`` thoughts and attitudes, after which the patterns according to the categories were analyzed as characteristics. This study is a significant endeavor in examining grandmothers and grandmothers-to-be who are being on their life``s transition period through their own perspective.

      • KCI등재

        운영 효율성을 고려한 감염병 전문병원의 일반병동 건축계획에 관한 연구

        은비 ( Han Eunbee ),순정 ( Kwon Soonjung ) 한국의료복지건축학회 2021 의료·복지 건축 Vol.27 No.4

        Purpose: As the need for a hospital specializing in infectious diseases has increased, construction is being promoted. Hospitals specializing in infectious diseases receive some state subsidies, but in the case of private hospitals, hospital operation efficiency should be considered to prevent cost loss. Therefore, we aim to derive a building plan for a general ward in a hospital specializing in infectious diseases that can be used not only in normal times but also in times of crisis. Methods: In this study, relevant literature review and field interviews were conducted with medical staff working in facilities designated as infectious disease hospitals. Results: The general ward building plan of the hospital specializing in infectious diseases was classified into three categories and presented. 'Spatial composition' for nursing unit and ward zoning, 'Spatial plan' for ward space conversion in normal times and crises, 'Bedroom plan' for effective dimensions and area of the ward. Implications: It can be used as a guideline when designing an infection-facility ward. And it can be a basis for inducing improvements to prevent infection in the ward of existing medical facilities.

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