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간질환에 있어서의 혈청 Alkaline Phosphatase Isozymes 에 관하여
이상용,고대전,박실무,이기환,김종숙,지무영 대한소화기학회 1978 대한소화기학회지 Vol.10 No.2
Cellulose acetate electrophoresis of serum alkaline phosphatase was done with sera of 45 patients with hepatitis, 47 patients with liver cirrhosis, 48 patients with hepatoma and 6 normal persons. Results demonstrated 4 distinct isoenzyme bands in liver diseases and the most prominent isoenzyme fraction was ey-phosphatase. The presence of the fast liver isoenzyme fraction was more frequent in patients with hepatoma than patients with other liver diseases. Intestinal alkaline phosphatase was observed in a few patients of liver diseases. In hepatoma patients, there was no significant difference in the distributions of alkaline phosphatase isoenzymes according to age, but the presence of the fast liver fraction was commoner in male than female. We concluded that the fast liver isoenzyme fraction was one of the valuable laboratory findings suggesting hepatoma.