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        유전분 갑상선종 1 예

        강영우,김현철,박성배,김상표,권건영,이인규,박기락,조성래,박근용,한성엽 대한내분비학회 1995 Endocrinology and metabolism Vol.10 No.2

        Amyloidosis is a systemic disorder of unknown etiology, The pathophysiological precess is caused by deposition of amyloid fibrils in tissues of the body. Almost any organ in the body can be affected, but amyloid goiter is a very rare presentation. A definitive diagnosis of amyloidosis requires tissue examination using special stains and electron microscopy. We had recently experienced a case of 62 year-old man who was found to have amyloid goiter after thyroid surgery. The patient was admitted Keimyung University Medical Center for evaluation of rapid growing thyroid mass and lobectomy of right thyroid gland was performed. The light microscopic finding showed eosinophilic hyalinized stroma containing one thick-walled blood wessel in the hematoxyline and eosin stain. Congo-red stain on polarized light showed apple-green birefringence of amyloid in thyroid and abdominal fat tissues. Using the PAP method, nodular deposits of amyloid in the stroma and blood vessels are stained positively with anti-AA serum. Electron microscopic finding showed randomly arranged and nonbranching fibrillary rods in the stroma(J Kor Soc Endocrinol 10: 125-130, 1995).

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        기능성 소화불량환자에서 체감각 , 뇌간청각 및 시각 유발전위

        강영우,한승엽,임정근 대한소화기학회 1997 대한소화기학회지 Vol.29 No.6

        Background/Aims: Although gastrointestinal dysmotility have played an important role in pathophysiology of functional dyspepsia, visceral perception abnormalities due to visceral hypersensitivity are now thought to be a major pathophysiologic mechanism of functional dyspepsia. Visceral hypersensitivity occurred at both visceral afferent pathway and autonomic regulation of central system. The present study was performed to evaluate the possible role of abnormal central perception in the pathophysiology of functional dyspepsia by using various evoked potentials. Methods: The study population consisted of 22 patients with functional dyspepsia and 22 healthy volunteers attending Keimyung University hospital from June 1995 to December 1995. They were studied somaiosensory evoked potentials(SSEP), brainstem auditory evoked potentials(BAEP) and visual evoked potentials(VEP) and compared the absolute latencies, interpeak latencies and amplitudes of each evoked potential between two groups. Results: There were no significant differences in absolute latencies of EP, N13, N19 and P22 waves and amplitudes of EP, N13 and N19/P22 at SSEP between functional dyspepsia and norrnal control. There were no significant differences in absolute latencies of I, II, III, IV and V waves, and interpeak latencies of I -III, m- V and I V at BAEP between functional dyspepsia and normal control. There were no significant differences in absolute latencies and amplitudes of P100 at VEP between functional dyspepsia and normal control. Conclusions: The present study could not reveal abnormal central percepition by using somatosensory, auditory and visual evoked potentials in patients with functional dyspepsia.

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