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PDGF와 $TGF-{\beta}1$이 배양 인체 치은 섬유모세포와 치주인대세포의 활성에 미치는 영향
정순규,남궁혁,신형식,Chung, Soon-Kyu,Nam, Goong-Hyuk,Shin, Hyung-Shik 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.1
The migration and proliferation of periodontal ligament cells are desired goal of periodontal regeneration therapy. PDGF and $TGF-{\beta}1$ are well known to regulate the cell activity of mesenchymal origin cell. The purpose of this study was to determine the effects of these growth factors on human gingival fibroblast and periodontal ligament cell actvity, and to identify the regulatory effect of $TGF-{\beta}1$ on the response to PDGF by MIT assay. Human gingival fibroblast and periodontal ligament cells were cultured from extracted teeth for non-periodontal reason. Cultured human gingival fibroblast and periodontal ligament cells in vitro were treated with polyperpetide growth factor PDGF and $TGF-{\beta}1$ in both a dose and time - dependent manner. Cell morphology were determined by inverted microscope and cell acitivity were determined by MIT assay. The result of this study demonstrated that PDGF and $TGF-{\beta}1$ were not changed the morphology of these cell compared with control group. PDGF or $TGF-{\beta}1$ increased cell activity of periodontal ligament cell in dose and time dependent manner but gingival fibroblast were decreased to the level of control group at third day. Additionally, incubation with $TGF-{\beta}1$ addition to PDGF resulted in a enhanced cell activity of PDGF. Therefore, cell acitivty of gingival fibroblast were not changed compared with control group. This stiudy demonstrates that PDGF and $TGF-{\beta}1$ are major mitogens for human periodontal ligament cell in vitro, and $TGF-{\beta}1$ is a regulator of cell activity to PDGF in human gingival fibroblast and periodontal ligament cell.
군용 직렬형 하이브리드 전기 차량을 위한 회생제동 협조제어 시스템의 압력제어 영향에 관한 연구
정순규,최현석,Jeong, Soonkyu,Choi, Hyunseok 한국군사과학기술학회 2016 한국군사과학기술학회지 Vol.19 No.4
In this research, the effect of the pressure control of cooperative control system with regenerative brake for a military series hybrid-electric vehicle was studied. A cooperative control system with regenerative brake was developed to maximize regenerative energy from electric traction motors of the vehicle. However, the pressure control method of the system was modified to solve a time delay problem and it deteriorates the performance of the system. A Simulink model including the hybrid-electric components, the cooperative control system with regenerative brake, and the vehicle dynamics was developed and used to find a solution. The regenerative energy ratio with respect to the whole brake energy was increased in this research from less than 60 % to over 80 %.
WPAN에서 QoS를 보장하는 분산적인 PNC 선출 방법
정순규,유상조,Jeong, Soon-Gyu,Yoo, Sang-Jo 한국통신학회 2007 韓國通信學會論文誌 Vol.32 No.2B
WPAN은 비교적 좁은 영역에서 통신이 수행되고, PNC라 불리는 중앙 조정장치가 중심이 돼서 네트워크가 조직되고 운영된다. 그리고 주요 응용분야는 방범장치, 건강관리 장치 등이 있을 수 있다. 이런 네트워크는 실시간성을 보장하는 것이 중요한데, PNC가 더 이상 동작하지 못해서 통신이 끊어지면 심각한 문제가 발생할 수 있기 때문에 이런 상황에서 다음 PNC를 빠르게 선출하는 것이 필요하다. 본 논문에서는 새로운 PNC를 선출할 때의 기준으로 QoS 보장가능정도와 주변 디바이스와의 연결성을 고려하여 기존의 PNC가 커버하던 영역을 최대한 보장하고 네트워크의 깨짐 및 분할 현상을 막고 QoS도 보장하는 분산적 PNC 선출방법을 제안한다. 저속 WPAN의 표준인 IEEE 802.15.4에 기반을 두는 시스템을 고려하였고, 모의실험결과 QoS와 주변 디바이스와의 연결성을 최대한 보장하면서 빠른 시간에 PNC를 선출할 수 있음을 알 수 있다. WPANs are formed in relatively small area and a PNC that serves as a central control device plays an important role in the operation and organization of a piconet. Typical applications of WPANs are security system and health monitoring system. In these type of systems, guaranteeing realtime service is very important, and communications cannot take place when the PNC malfunctions. Thus, in this situation, it is necessary to elect a new PNC as soon as possible. For this reason, we propose distributed PNC election scheme that considers not only QoS support but also network connectivity to avoid possible network partition. Simulation results show proposed mechanism can select PNC with guaranteeing QoS and connectivity for a limited period.
금속-절연체 전이 임계온도센서를 이용한 보상식 화재 감지기 개발
정순규,김현탁 한국화재소방학회 2014 한국화재소방학회논문지 Vol.28 No.1
A Compensation-type fire detector (CFD) is operated with two functions of a differential-temperature detector and as afixed-temperature detector. The differential-temperature detector observes a rate of temperature increase, and the fixedtemperaturedetector measures a given fixed temperature. The differential-temperature detector does not observe the outbreakof fire in slowly increasing temperature conditions, whereas the fixed-temperature detector is not able to observe theoutbreak of fire in conditions under predetermined temperature level. We developed a CFD to compensate for weaknessesof both detectors. To compensate for the disadvantages, a sensor of the sensor metal-insulator-transition criticaltemperaturesensor was used. Temperature coefficient of resistance is the sensitivity for sensor. At 55 oC, temperaturecoefficient of resistance of metal-insulator-transition critical-temperature sensor was 14.15%. Temperature coefficient ofresistance of thermistor was about 0.5%. This CFD was operated as two ways that fixed-temperature detector and differential-temperature detector in one sensor. 보상식 화재 감지기는 일정한 온도 상승률 이상으로 빠르게 상승하는 경우에 작동하는 차동식 화재 감지기의 기능과정온점에 이르렀을 때 작동하는 정온식 화재 감지기의 기능을 모두 가진 감지기다. 이 화재 감지기는 정온점 이하에서발생하는 화재를 감지하지 못하는 정온식 화재 감지기의 단점과 불꽃없이 천천히 타는 현상과 같이 천천히 열이 증가하는 화재를 감지하지 못하는 차동식 화재 감지기의 단점을 보완하기 위해 개발된다. 이것을 위해 우리는 이 감지기의 센서로 금속-절연체 전이 임계온도센서를 이용했는데 이 센서의 감도를 결정하는 저항온도계수가 55 oC일 때 14.15%로써,서미스터(약 0.5%)보다 큰 값이다. 이 센서는 하나의 센서가 정온점 이하에서는 차동 기능, 정온점 이상에서는 정온 기능을 모두 가진다.