심방유동환자의 척추마취 종료직후 발생한 전신경련 증례

강남연,김익종 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.2

A male patient with atrial fibrillation aged 74 years underwent an operation for benign hypertropic prostate under spinal anesthesia. Post-operatively he suffered from convulsions but was discharged without sequlae on the 1Sth post-opergtive day. The causes of symptcnmatic fits include hypoxia in general, cerebral edema, embolus hyperpyrexia, drugs, hypoglycemia, hypocalcemia and conccmitant diseases including cerebrovascular accidents. Probably a combination of some of these factors caused have caused post-operative or post-spinal anesthesia convulsione.

성견 경골에서 자가장골이식이 임플란트 골유착에 미치는 영향

강남연,김명래,김선종 이화여자대학교 의과대학 2009 EMJ (Ewha medical journal) Vol.32 No.2

Objectives:This study was performed to evaluate the effect of autogenous iliac particulated marrow cancellous bone graft on osseointegration of implants in the dog tibia which has a loose bone marrow. Methods:Three mongrel dogs, weighing about15kg or more, and RBM(resorbable blasted media) AVANAⓡ implants(Osstem Inc., Korea) were used in this study. In the control groups, 2 implants sites were prepared conventionally with drills in the left metaphysic of tibia and 2 implants were placed in each dog under general anesthesia. In the experimental groups, 2 implant sites were prepared with drills. and the particulated marrow cancellous bone, which was obtained from the right ilium,was packed into both prepared sites with osteotomes in the right metaphysic of tib-ia in each dog. Two implants were placed. A total of 12 implants were placed in 3 dogs. The animals were sacrificed at 8 weeks after implant placement. The specimens were taken and embedded into the resin. H & E stain was done. The undecalcified specimens were prepared for histological examination and histomorphometric analysis of bone-implant contact ratios. The Mann-Whitney test was used to compare both groups.Values of p<0.01were considered statistically significant. Results:In the cross-sectional radiographs of the control group no trabecular bone was observed in the marrow space and the implant was surrounded with radiolucent marrow space. In the experimental group Some radioaque trabecular bone was observed in the marrow space of tibia and some of the trabecula was contacted with implant surface. Histologically,in the control group few trabecular bone was observed in marrow space and there was poor osseointegration in the marrow. In the experimental group most marrow space was filled with the trabecular boneand the implant surface was contacted with trabecular bone. In histomorphomeric analysis the bone-implant contact ratio of the experimental group(75.6%) was significantly higher than that of the control group(27.1%,p<0.01). Conclusion:The autogeneous bone graft into the loose bone marrow can be an option to improve the bone density and to get better osseointegration of dental implants.

新生兒 및 嬰兒手術의 痲醉에 對한 考察

金卜烈,姜南連 順天鄕大學校 1977 의대논문집 Vol.2 No.-

Anestheic complications occur more frequcntly during the first decade of life than in any other decade. In order to provide safe and satisfactory anesthesia for the newborns and infants the anesthesiologist must thoroughly understand the principles of modern anesthetic practice and newborn infants differ from adults in anatomy, physiology and pharmacologic response to drugs. We have been evaluate 54 cases of anesthesia in newborn and infant surgery performed during last 3 years from Nov., 1973 to Oct.,1976 in Chosun University Hosptal. The important diseases in newborn and infant surgery are inguinal hernia, congenital disease, intussusception and burn. Among 54 cases, 34 cases are perfornmed in department of a general surgery. Inhalation anesthetics are halothane and ether. Inhalation anesthetic technique used nonrebreathing system with Ambu bag. This technique has minimal dead space and low resistance and allow convenient assistance or control of ventilation. Ketamine has valuable for burn dressing and superficiaI minor surgery such as abscess, especially in children whom intravenous sites are difficult to obtain.

Diazepam 이 수술전야수면제로서의 임상적연구 : 이중맹검법(二重盲檢法)

손익종,강남연 대한마취과학회 1976 Korean Journal of Anesthesiology Vol.9 No.2

The hypnotic activity of diazepam was compared with that of inactive placebo in a double- blind, randomized study in 40 surgical patients the night before their scheduled procedures. Diazepam per os (10mg) produces a pattern of response that differed markedly from that of the placebo. The patient receiving diazepam fell asleep sooner, slept more soundly and steadily and more felt they had been helped to sleep, while fewer awoke during the night. The significant difference Was obtained in both hypnotic and ataractic effects between diazepam and inactive placebo. Neither diaxepam nor inactive placbo caused marked changes in vital signs or any serious side effects.

Ambu Valve 를 이용한 소아마비례 보고

박정훈,김복열,강남연,김동국 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.2

The choice fo equipment for the administration of anesthesia depends to a considerable extent upon personal preference. Underlying factors must guide this choice, however. Equipment is suited to the individual patient, with especial care to avoid resistance, dead space, fatigue, and trauma, since all of these insults are easily imposed upon small patients. As we have had good experience in pediatric pnesthesia with the Ambu valve and the results were satisfactory, we report with discussion of references.

寒冷蕁痲疹 1例報告

孫益鍾,金卜烈,朴正勳,姜男連 順天鄕大學校 1974 의대논문집 Vol.1 No.-

Mg-Sn 이원계 합금에서의 이차재결정 현상 고찰

김성경 ( Seong Gyeong Kim ),강전연 ( Jun Yun Kang ),하헌영 ( Heon Young Ha ),박노진 ( Jin Park ),임창동 ( Chang Dong Yim ),강남현 ( Nam Hyun Kang ) 대한금속재료학회(구 대한금속학회) 2014 대한금속·재료학회지 Vol.52 No.6

The process of secondary recrystallization in the Mg-6Sn binary alloy that initially had bimodal grain size distribution was observed. The prevalence of the {0001}//sheet plane orientation in the initial texture was destroyed and the texture was transformed to a very strong {2□□0}-type during solution heat treatment at 480 ℃. The grain boundary character was analyzed using EBSD, in which no preference of the CSL boundary among the grain boundaries of {2□□0}- oriented grains was evident. It was observed that some fine grains were isolated within coarse {2□□0} oriented grains due to limited boundary migration and these boundaries belonged to CSL boundaries. These analyses confirmed that the secondary recrystallization was driven by the general high-angle grain boundaries surrounding {2□□0}-oriented grains. (Received July 31, 2013)

麻醉前 投藥劑 Diazepam 및 Atropine Sulfate 常用量 投與가 미치는 血漿成長호르몬 値

孫益鍾,金卜烈,朴正勳,姜南連,金東국 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.3

This study was undertaken to investigate the effect of premedicants, diazepam end atropine sulfate in ten surgical patients by determining plasma human growth hormone. Also HGH. PIAKTT was utilized as a kit for determination of human growth hormone by radioimmunoassay (double antibody system). The plasma HGH level before administration of premedicants was 1.82±0.83 ng/ml and 2.03±0.84 ng/ml at 60 minutes after administration of premedicants so that clinical significance of the results was absent. Sex ratio between male and female patients was 5:5, mean ages 39.2±12.1 and average body weights 55.5±8.5㎏. Consequently, there was no significant change in plasma human growth hormone during one hour of premedication and result were within normal limits.

인체 피부 섬유아세포에서 자외선 조사에 대한 녹차나무 씨 추출물의 보호효과

김옥경(Ok Kyung Kim),남다은(Da-Eun Nam),이민재(Min-Jae Lee),강남길(Namgil Kang),임재연(Jae-Youn Lim),이정민(Jeongmin Lee) 한국식품영양과학회 2014 한국식품영양과학회지 Vol.43 No.1

본 연구는 아직 기능성 입증이 미비한 녹차나무 씨 추출물을 사용하여 자외선을 조사한 인체 피부 섬유아세포에서 항산화 효능과 MMPs 및 collagen의 변화를 살펴봄으로써 광노화 억제 효능을 평가하였다. 녹차나무 씨 추출물 농도별 라디칼 소거능을 살펴보기 위하여 ABTS와 DPPH 라디칼 소거능을 측정한 결과 녹차나무 씨 추출물 농도 의존적으로 소거능을 증가시켰다. 25 mJ/㎠ 자외선을 조사한 인체 피부 섬유아세포에서 녹차나무 씨 추출물의 농도별(10 μg/mL, 30 μg/mL, 50 μg/mL) 처리가 미치는 영향을 살펴보았다. 항산화 효소(SOD, GPx, catalase) 활성의 변화를 측정한 결과에서 자외선 조사에 의하여 감소한 활성을 녹차나무씨 추출물의 처리가 유의적으로 증가시켰음을 확인하였다. 또한 녹차나무 씨 추출물의 처리는 MMP-1의 합성을 감소시키고 collagen의 합성을 증가시켰으며, MMP-1, MMP-3, MMP-9의 mRNA 발현을 감소시키고 type-1 collagen의 mRNA 발현을 증가시켰다. 따라서 녹차나무 씨 추출물은 항산화 활성을 지녔으며 자외선 조사에 의한 활성산소종으로부터 보호하여 MMPs 발현을 감소시키고 collagen 분해를 억제시켜 피부 노화억제에 긍정적인 영향을 미쳤으며, 이러한 기능성 입증으로 녹차나무의 활용 증가를 기대할 수 있다. In this study, we investigated the protective effects of green tea seed extract (GSE) against UVB-induced skin damage in human skin fibroblasts. GSE was first analyzed for antioxidant activity using 1,1-diphenyl-2picrylhydrazyl(DPPH) and 2,2"-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging assays. Treatment of UV-irradiated fibroblast with GSE at 10~50 μg/mL significantly increased DPPH and ABTS radical scavenging activities in a dose-dependent manner. GSE treatment inhibited matrix metalloproteinase (MMP-1, MMP-3, and MMP-9) expression and MMP-1 secretion caused by UVB irradiation. Moreover, treatment with GSE significantly increased type-1 collagen expression and production. We next examined levels of antioxidative enzymes (SOD, catalase, and GPx). Reduced antioxidative enzyme activities caused by UVB irradiation were recovered by treatment with GSE at 30 μg/mL and 50 μg/mL. In conclusion, these results show that GSE has protective effects against UVB-induced skin damage in human skin fibroblasts by regulating antioxidative defense systems and MMP expression.