http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
좀비 드라마의 부권 서사: <워킹 데드>의 남성성과 부성 분석
김태형 ( Kim¸ Taehyung ) 대한영어영문학회 2021 영어영문학연구 Vol.47 No.2
The research examines the logic of the patriarchal society that runs throughout the narrative of the television series The Walking Dead. Males in the zombified world often strike out the living dead through violence, which affects people’s sometimes unethical and deadly behaviors toward other human beings. The family and community also take advantage of such masculine violence for their survival. The protagonist of the series, Rick Grimes, becomes the head of the family and survivor group by eliminating or winning over competitors for the name of the father. Rick’s son, Carl, stands up for his biological father among other father figures, supporting Rick’s patrilineal system. Women in the community need toughness and masculinity to adapt to the changed circumstances; mother figures in Rick’s family die providing house work, which is especially undervalued in a zombie apocalypse. Carl has to decide not between his mother and his father in an Oedipal triad but between fathers as a consequence of his mother’s absence. The logic of patriarchy takes up the main narrative of the series, and the longing for the missing Rick ultimately proves the father’s symbolic authority in his absence. (Kunsan National University)
Kim, TaeHyung,Tyndel, Marc S.,Kim, Hyeoung Joon,Ahn, Jae-Sook,Choi, Seung Hyun,Park, Hee Jeong,Kim, Yeo-kyeoung,Kim, Soo Young,Lipton, Jeffrey H.,Zhang, Zhaolei,Kim, Dennis (Dong Hwan) American Society of Hematology 2017 Blood Vol. No.
<P>Somatic mutations commonly detected in a variety of myeloid neoplasms have not been systematically investigated in chronic myeloid leukemia (CML). We performed targeted deep sequencing on a total of 300 serial samples from 100 CML patients; 37 patients carried mutations. Sixteen of these had evidence of mutations originating from preleukemic clones. Using unsupervised hierarchical clustering, we identified 5 distinct patterns of mutation dynamics arising following tyrosine kinase inhibitor (TKI) therapy. This study demonstrates that patterns of mutation acquisition, persistence, and clearance vary but have a number of interesting correlations with clinical outcomes. Mutation burden often persisted despite successful TKI response (pattern 1), providing indirect evidence that these mutations also originated from preleukemic mutations, whereas patients exhibiting mutation clearance (pattern 3) showed mixed clinical outcomes. Unsurprisingly, patients acquiring new mutations during treatment failed TKI therapy (pattern 2). These patterns show that CML mutation dynamics following TKI therapy are markedly distinct from other myeloid neoplasms. In summary, clinical implications of mutation profiles and dynamics in CML should be interpreted with caution.</P>
두꺼운 꼬리 분포와 레버리지효과를 포함하는 확률변동성모형에 대한 최우추정: HMM근사를 이용한 최우추정
TaeHyung Kim,박정민 한국통계학회 2022 응용통계연구 Vol.35 No.4
두꺼운 꼬리 분포와 레버리지효과 등의 금융시계열의 전형적인 특징에도 불구하고 기존 빈도론적 접근법에서는 이를 명시적으로 포착하는 확률변동성모형이 제시된 바 없다. 본 연구는 빈도론적 접근법에서 수익률 금융시계열의 두꺼운 꼬리 분포와 레버리지효과를 명시적으로 포착할 수 있는 근사적인 확률변동성모형 설정을 제시하고이에 대한 Langrock 등 (2012)의 HMM근사를 이용한 최우추정을 제안한다. 본 연구는 다양한 모의실험과 실증분석을 통해 본 연구에서 제안하는 근사모형이 두꺼운 꼬리 분포와 레버리지효과를 정밀하고 효과적으로 추정할 수 있음을 보인다.
Kim, TaeHyung,Tyndel, Marc S.,Zhang, Zhaolei,Ahn, Jaesook,Choi, Seunghyun,Szardenings, Michael,Lipton, Jeffrey H.,Kim, Hyeoung-Joon,Kim Dong Hwan, Dennis Elsevier 2017 Leukemia research Vol.59 No.-
<P><B>Abstract</B></P> <P><B>Objective</B></P> <P>The development of tyrosine kinase inhibitors (TKIs) has significantly improved the treatment of chronic myeloid leukemia (CML). However, approximately one third of patients are resistant to TKI and/or progress to advanced disease stages. TKI therapy failure has a well-known association with <I>ABL1</I> kinase domain (KD) mutations, but only around half of TKI non-responders have detectable <I>ABL1</I> KD mutations.</P> <P><B>Method</B></P> <P>We attempt to identify genetic markers associated with TKI therapy failure in 13 patients (5 resistant, 8 progressed) without <I>ABL1</I> KD mutations using whole-exome sequencing.</P> <P><B>Results</B></P> <P>In 6 patients, we detected mutations in 6 genes commonly mutated in other myeloid neoplasms: <I>ABL1</I>, <I>ASXL1</I>, <I>DNMT3A</I>, <I>IDH1</I>, <I>SETBP1</I>, and <I>TP63</I>. We then used targeted deep sequencing to validate our finding in an independent cohort consisting of 100 CML patients with varying drug responses (74 responsive, 18 resistant, and 8 progressed patients). Mutations in genes associated with epigenetic regulations such as <I>DNMT3A</I> and <I>ASXL1</I> seem to play an important role in the pathogenesis of CML progression and TKI-resistance independent of <I>ABL1</I> KD mutations.</P> <P><B>Conclusion</B></P> <P>This study suggests the involvement of other somatic mutations in the development of TKI resistant progression to advanced disease stages in CML, particularly in patients lacking <I>ABL1</I> KD mutations.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Acquisition of somatic mutation is associated with TKI therapy failure and progression in CML patients. </LI> <LI> Exome sequencing revealed mutations in 6 genes: <I>ABL1, ASXL1, DNMT3A, IDH1, SETBP1,</I> and <I>TP63.</I> </LI> <LI> Somatic mutations is responsible for TKI resistance esp. lacking <I>ABL1</I> KD mutations. </LI> </UL> </P>
Reflective composite sheet design for LCD backlight recycling.
Kim, Taehyung,Kim, Kibeom,Lee, Eun Soo,Jeong, Won Young,Lim, Dae Young,Choi, Suk-Won Optical Society of America 2014 Optics express Vol.22 No.9
<P>We have designed a reflective composite sheet consisting of a birefringent polymer matrix and isolated isotropic or minimally birefringent fibers. The optical properties of the sheet have been investigated in terms of the width, spacing, and thickness of the individual fibers. Commercial software (FDTD Solution) was used to simulate the reflectance of the proposed sheet, and conventional processes such as cast-film extrusion in combination with solid-state drawing were used to manufacture the multilayer composite sheet. The measured and simulated reflectance spectra confirm the feasibility of employing the sheet as a reflective polarizer.</P>
Computation of serrated trailing edge flow and noise using a hybrid zonal RANS-LES
Taehyung Kim(김태형),Seunghoon Lee(이승훈),Soogab Lee(이수갑) 한국소음진동공학회 2012 한국소음진동공학회 학술대회논문집 Vol.2012 No.4
The evaluation of a zonal RANS-LES approach is documented for the prediction of broadband noise generated by the flow past unmodified and serrated airfoil trailing edges at a high Reynolds number. A multi-domain decomposition is considered, where the acoustic sources are resolved with a LES sub-domain embedded in the RANS domain. A stochastic vortex method is used to generate synthetic turbulent perturbations at the RANS-LES interface. The simulations are performed with a general-purpose unstructured control-volume code FLUENT. The far-field noise is calculated using the aeroacoustic analogy of Ffowcs Williams-Hawkings. The results of the simulation are validated through the full-scaled wind turbine acoustic measurements. It is found that the present approach is adequate for predicting noise radiation of serrated trailing edge flow for low noise rotor system.
Bayesian Markov Chain Monte Carlo algorithm for Feller square-root stochastic volatility models
TaeHyung Kim(김태형),Jeongmin Park(박정민) 한국계량경제학회 2017 JOURNAL OF ECONOMIC THEORY AND ECONOMETRICS Vol.28 No.3
본 연구는 Feller제곱근 확률변동성모형에 대한 새로운 베이지언 추론 알고리듬, 알고리듬의 성과에 대한 모의실험 결과, 그리고 알고리듬을 이용한 실증분석 결과를 제시한다. 본 연구의 알고리듬은 수익률과 조건부분산의 결합확률밀도함수로부터 유도되는 조건부분산의 GIG분포 확률커널을 정규분포로 근사하는 방법을 이용하므로 도약과정이나 두꺼운 꼬리를 가지는 수익률 분포를 포함하는 확장모형에도 쉽게 적용될 수 있다. 또한 본 연구의 알고리듬과 파티클필터를 통해 얻은 PIT를 이용하는 확률변동성모형 진단 통계량들의 사이즈와 검정력을 비교하는 모의실험 결과를 제시한다. 파라미터 추정에 따른 불확실성에 영향을 받지 않는 대표적인 비모수 검정인 Hong and Li (2005) 검정과 일반화된 잔차의 정규성을 이용하는 고전적 진단통계량들의 사이즈와 검정력에 대한 모의실험 결과, 고전적 진단통계량들의 사이즈왜곡이 심각하지 않을 수 있으며 검정력 또한 Hong-Li옴니버스검정(Q)보다 좋을 수 있는 것으로 나타났다. We develop a new Bayesian Markov Chain Monte Carlo algorithm for Euler-discretized Feller square-root stochastic volatility models and demon-strate the performance of our algorithm through simulations and empirical anal-yses. Specifically, our algorithm use the Laplace approximation of the posterior density of conditional variance, which is the probability kernel of the generalized inverse gaussian distribution, derived from the joint density of return and condi-tional variance so that it can be easily applied to the extended stochastic volatility models with such as fat-tailed distributions or Le´vy jump processes. In addition, we conduct the simulation experiment investigating and comparing the size and power of the parametric specification tests checking certain finite-dimensional moment conditions without correction for parameter estimation uncertainty with that of the nonparametric Hong and Li (2005)’s omnibus test which is not af-fected by parameter estimation uncertainty. The parametric and nonparametric tests are based on the probability integral transform of the prediction densities of returns obtained using auxiliary particle filter algorithms. Our experiment re-sult shows that the classical parametric specification test may have no worse size distortion and better power than Hong and Li (2005)’s test.