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미만형 신경섬유종 병변 부위 두피에 발생한 발모벽 1 예
양진석(Jin Seok Yang),박현정(Hyun Jeong Park),이현정(Hyun Jeong Lee),백승철(Seung Cheol Baek),변대규(Dae Gyoo Byun) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.10
A 13-year-old girl presented in our unit with progressive alopecia and a long history of edematous scalp in the occiput. Biopsy specimen of a lesion showed two-type pathologic abnormality consisting of diffuse neurofibroma in the lower portion and trichotillomania in the upper portion. Since the tumor spread diffusely through the lower dermis and subcutaneous fat tissue without destroying surrounding structures, we concluded that the trichotillomania might result from repetitive scratching or other traumatic behavior at the same site of underlying diffuse nerurofibroma. We reported a case of the concomitant occurrence of trichotillomania associated with diffuse neurofibroma. (Korean J Dermatol 2001;39(10): 1152-1256)
Park, Jong Hyuk,Kim, Jung Ryul,Shin, Sung Jin,Lee, Nae Ho,Lee, Hyung Suk,Lim, Young Jin Informa Healthcare 2011 Journal of plastic surgery and hand surgery Vol.45 No.4
<P>Diffuse neurofibroma presents as a diffuse overgrowth of subcutaneous tissue, and usually involves the face, scalp, neck, or chest, but rarely occurs in the back. The management of large soft tissue defects after wide resection of a diffuse neurofibroma is a major surgical challenge. We report the case of a diffuse neurofibroma of the back that required reconstruction after wide resection of the tumour using an expanded myocutaneous advancement flap and a tissue expander. Tissue expansion is essentially a simple technique for expanding available normal skin, and it provides optimally matched skin in terms of colour, texture, hair-bearing qualities, and sensation.</P>
김성애 ( Sung Ae Kim ),강민철 ( Min Chul Kang ),정상립 ( Sang Lip Chung ),이규석 ( Kyu Suk Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.6
Diffuse neurofibroma is an uncommon subtype of neurofibroma that occurs principally in children and young adults. It is most common in the head and neck region and appears clinically as a plaque-like elevation of the skin. A 3-year-old girl presented to our hospital with a complaint of skin-colored elevated plaques with hair on her lower back since birth. An ultrasonogram showed several 5∼10 mm sized subcutaneous hypoechoic nodules with increased vascularity. The histopathologic examination revealed ill-defined, uncapsulated infiltrative, spindle shaped cells within the dermis and subcutaneous tissue. Immunohistochemical examination with antibodies to S-100 protein showed positive. We report a rare case of diffuse neurofibroma with hair. (Korean J Dermatol 2009;47(6):696∼698)
백진옥 ( Jin Ok Baek ),이혜영 ( Hye Young Lee ),김민 ( Min Kim ),노주영 ( Joo Young Roh ),이종록 ( Jong Rok Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.8
A 37-year-old man presented with a 1-year history of asymptomatic ill-defined subcutaneous thickening with overlying whitish hairs on right occipital scalp. Histopathologic examination from this subcutaneous mass revealed neurofibromatous tissue with a diffuse infiltrative growth. S-100 protein staining showed decreased melanocytes and melanin in hair follicles. He was diagnosed as a diffuse neurofibroma associated with poliosis. To our knowledge, only two cases of poliosis associated with neurofibroma have ever been reported in English. (Korean J Dermatol 2007;45(8):811∼813)
차상희 ( Sang Hee Cha ),조상현 ( Sang Hyun Cho ),이정덕 ( Jeong Deuk Lee ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.3
Diffuse neurofibroma is an uncommon variant of neurofibroma that usually presents on the head and neck. It is common in children and young adults. Clinically, the lesion presents as large, poorly circumscribed swelling. A 25 year-old female presented with diffuse swelling on the occipital region of the scalp for several years. Magnetic resonance imaging showed 8x9 cm sized, ill defined infiltration on the occipital scalp. The histologic examination revealed unencapsulated loosely arranged spindle cells within the dermis and subcutaneous tissue. Meissnerian differentiation was observed within the tumor cells. The tumor cells were positive for S-100 protein. We report a case of diffuse neurofibroma on the occipital region of the scalp. (Korean J Dermatol 2008;46(3):355∼358)
Diffuse Neurofibroma Presenting with Spontaneous Intra-Tumoral Hemorrhage
Kwak, Seung-Won,Han, Young-Min,Park, Young-Sup The Korean Neurosurgical Society 2006 Journal of Korean neurosurgical society Vol.39 No.6
This report describes a case of diffuse neurofibroma[DNF] that presented with spontaneous intratumoral hemorrhage. A 31-year-old man with cutaneous manifestations typical of neurofibromatosis type 1[NF1] was referred to hospital with a progressively expanding scalp swelling. Magnetic resonance imaging[MRI] showed an acute hematoma surrounded by a dense mass on the parietooccipital scalp. Plain skull radiographs and a computed tomography[CT] scan revealed bony defects in the occipital bone around the lambdoid suture and the skull base, including the sphenoid and petrous bones. The tumor extended to the upper cervical region and infiltrated through the fascia of the musculature. The tumor and adjacent soft tissue were highly vascular, which made surgical resection difficult. We describe the clinical, radiological and pathological features of this patient md discuss the surgical methods used to avoid a life-threatening hemorrhage during surgery.