The Influence of Using Time, Storage and Exposure to Atmosferic Conditions on Attenuation of Ear-muffs

Ewa Kotarbi?ska,Emil Kozłowski 한국소음진동공학회 2003 한국소음진동공학회 국제학술대회논문집 Vol.2003 No.8

Contrast-Enhanced Spectral Mammography: Comparison with Conventional Mammography and Histopathology in 152 Women

Elzbieta Luczyn´ ska,Sylwia Heinze-Paluchowska,Sonia Dyczek,Pawel Blecharz,Janusz Rys,Marian Reinfuss 대한영상의학회 2014 Korean Journal of Radiology Vol.15 No.6

Objective: The goal of the study was to compare conventional mammography (MG) and contrast-enhanced spectral mammography (CESM) in preoperative women. Materials and Methods: The study was approved by the local Ethics Committee and all participants provided informed consent. The study included 152 consecutive patients with 173 breast lesions diagnosed on MG or CESM. All MG examinations and consults were conducted in one oncology centre. Non-ionic contrast agent, at a total dose of 1.5 mL/kg body weight, was injected intravenous. Subsequently, CESM exams were performed with a mammography device, allowing dual-energy acquisitions. The entire procedure was done within the oncology centre. Images from low and high energy exposures were processed together and the combination provided an “iodine” image which outlined contrast up-take in the breast. Results: MG detected 157 lesions in 150 patients, including 92 infiltrating cancers, 12 non-infiltrating cancers, and 53 benign lesions. CESM detected 149 lesions in 128 patients, including 101 infiltrating cancers, 13 non-infiltrating cancers, and 35 benign lesions. CESM sensitivity was 100% (vs. 91% for MG), specificity was 41% (vs. 15% for MG), area under the receiver operating characteristic curve was 0.86 (vs. 0.67 for MG), and accuracy was 80% (vs. 65% for MG) for the diagnosis of breast cancer. Both MG and CESM overestimated lesion sizes compared to histopathology (p < 0.001). Conclusion: CESM may provide higher sensitivity for breast cancer detection and greater diagnostic accuracy than conventional mammography.

Synthesis of DOT Use of Beam End Protection for Extending the Life of Bridges

Aleksandra Radli?ska,Leslie Myers McCarthy,James Matzke,Francis Nagel 한국콘크리트학회 2014 International Journal of Concrete Structures and M Vol.8 No.3

As the national transportation infrastructure ages and deteriorates, many existing bridges require frequent and costly maintenance and repairs. The objective of this work was to synthesize new and existing types of beam end coatings and treatments that have been proven to extend the life of new and existing concrete and steel bridge beams. A comprehensive literature review, along with online surveys and phone interviews of State department of transportations (DOTs) and coating manufacturers was conducted to gather information about existing and recently developed technologies. The study revealed that while many promising coatings and treatments are offered on the market, there is a lack of readily available laboratory results that would enable direct comparison of the available methods. This finding applies in terms of the coatings’ durability and the potential for extending the service life of existing bridges. Most of the interviewed State DOTs’ personnel assessed the products listed in respective DOT’s Qualified Products Lists as performing ‘well’. However, there was significant variability between states in the type of the products used. Among the agencies contacted, none was able to suggest the most promising or advanced products, either for concrete or steel bridge beam end treatments. This suggests that comprehensive laboratory evaluation would be necessary for selecting the best available beam end treatments and coatings.

Design and Implementation of a Hybrid Path Planning Approach for Autonomous Lane Change Manoeuvre

Skačkauskas Paulius,Karpenko Mykola,Prentkovskis Olegas 한국자동차공학회 2024 International journal of automotive technology Vol.25 No.1

Autonomous vehicles are currently on their way and they have already started to gradually alter the fundamentals of the entire transport system. However, while in relatively near future, seeking to use their full potential during various urban traffi c scenarios, further developments must be done in such fi elds as the sensing and perception, path planning and control. This research work focuses on the path planning problems and proposes a novel hybrid path planning approach, specifi cally designed for an important and complex urban scenario—the lane change manoeuvre. The proposed hybrid path planner consists of two classical path planning approaches: the Bézier curves approach, which served as a primary planner, and the rapidly exploring random trees approach, which was used as a supplementary planner. The entire development process of the hybrid path planner is described systematically and in detail. To verify the effi ciency of the proposed hybrid path planner, experimental test drives, while using an autonomous research vehicle, were performed. The experimental results indicated that the real-time performance of the proposed hybrid path planning approach is eff ective and reliable. The path generated by the proposed hybrid approach is feasible, continuous, and can be executed by the autonomous vehicle.

INVESTIGATION OF CAVITATION PROCESS IN MONOTUBE SHOCK ABSORBER

Viktor Skrickij,Dzmitry Savitski,Valentin Ivanov,Paulius Skačkauskas 한국자동차공학회 2018 International journal of automotive technology Vol.19 No.5

The paper investigates cavitation effect which negatively influences the performance of a monotube shock absorber of road vehicle (passenger car). For better understanding of this phenomena, three physical models of shim stack valves are analyzed. Validation results allowed selecting the most appropriate valve model in presence of cavitation processes. A mathematical model of monotube damper with consideration of fluid compressibility and cavitation phenomena is developed. Simulation results are validated by experimental data obtained on hydraulic test rig. Based on the selected approach, a simplified method suitable for assessment of cavitation processes in automotive monotube shock absorbers is proposed. After investigation it is found that damping force when cavitation occurs mainly depends on the initial pressure and absorber inner diameter.

Novel biocidal N-halamine plastic based on poly(vinyl chloride): Preparation and characteristics

Marta Chylin´ ska,Halina Kaczmarek,Aleksandra Burkowska-But,Maciej Walczak 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.28 No.-

Preparation method of new biocidal plastics based on plasticized PVC has been elaborated. Thederivative of poly(4-vinylbenzyl chloride) containing N-halamine substituents has been mixed with PVCgranules and processed by dry blend extrusion and injection moulding. The properties of obtainedmaterial have been tested using SEM/EDX and thermogravimetry. The biocidal efficacy of modified PVCresin has been tested against two strains of bacteria: Escherichia coli (Gram-negative) and Staphylococcusaureus (Gram-positive). It was found that even small amount of biocidal component yields to efficient biocidal activity of thewhole plastic. Chemical composition and other properties of PVC remain almost unchanged

Recent status of SKA in Korea

Bong Won Sohn,SKA Korea 한국천문학회 2023 天文學會報 Vol.48 No.2

Synthesis of Novel 4-(1H-benzimidazol-2-yl)benzene-1,3-diols and their Cytotoxic Activity against Human Cancer Cell Lines

Monika M. Karpin´ ska,Joanna Matysiak,Andrzej Niewiadomy 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.10

One-pot synthesis of new biologically active 4-(1H-benzimidazol-2-yl)benzene-l,3-diols has been developed. The compounds were prepared by the reaction of aryl-modified sulfinylbis[(2,4-dihydroxyphenyl)methanethione]s with benzene-l,2-diamines. Their structures were identified using elemental, IR, lH-NMR, and mass spectra analyses. The developed method offers short reaction times, relatively large-scale synthesis, easy and quick isolation of the products, and good yields. The cytotoxicity in vitro against the 4 human cancer cell lines: SW707 (rectal), HCV29T (bladder), A549 (lung), and T47D (breast) was determined. The antiproliferative properties of some compounds studies were stronger than those of cisplatin, which was used as a comparator drug.

A Maximum-Likelihood Approach to Force-Field Calibration

Zaborowski, Bartłomiej,Jagieła, Dawid,Czaplewski, Cezary,Hałabis, Anna,Lewandowska, Agnieszka,Ż,mudziń,ska, Wioletta,Ołdziej, Stanisław,Karczyń,ska, Agnieszka,Omieczynski, Christian American Chemical Society 2015 JOURNAL OF CHEMICAL INFORMATION AND MODELING Vol.55 No.9

<P>A new approach to the calibration of the force fields is proposed, in which the force-field parameters are obtained by maximum-likelihood fitting of the calculated conformational ensembles to the experimental ensembles of training system(s). The maximum-likelihood function is composed of logarithms of the Boltzmann probabilities of the experimental conformations, calculated with the current energy function. Because the theoretical distribution is given in the form of the simulated conformations only, the contributions from all of the simulated conformations, with Gaussian weights in the distances from a given experimental conformation, are added to give the contribution to the target function from this conformation. In contrast to earlier methods for force-field calibration, the approach does not suffer from the arbitrariness of dividing the decoy set into native-like and non-native structures; however, if such a division is made instead of using Gaussian weights, application of the maximum-likelihood method results in the well-known energy-gap maximization. The computational procedure consists of cycles of decoy generation and maximum-likelihood-function optimization, which are iterated until convergence is reached. The method was tested with Gaussian distributions and then applied to the physics-based coarse-grained UNRES force field for proteins. The NMR structures of the tryptophan cage, a small α-helical protein, determined at three temperatures (<I>T</I> = 280, 305, and 313 K) by Hałabis et al. (J. Phys. Chem. B<x> </x>2012<x>, </x>116<x>, </x>6898−<lpage>6907</lpage>), were used. Multiplexed replica-exchange molecular dynamics was used to generate the decoys. The iterative procedure exhibited steady convergence. Three variants of optimization were tried: optimization of the energy-term weights alone and use of the experimental ensemble of the folded protein only at <I>T</I> = 280 K (run 1); optimization of the energy-term weights and use of experimental ensembles at all three temperatures (run 2); and optimization of the energy-term weights and the coefficients of the torsional and multibody energy terms and use of experimental ensembles at all three temperatures (run 3). The force fields were subsequently tested with a set of 14 α-helical and two α + β proteins. Optimization run 1 resulted in better agreement with the experimental ensemble at <I>T</I> = 280 K compared with optimization run 2 and in comparable performance on the test set but poorer agreement of the calculated folding temperature with the experimental folding temperature. Optimization run 3 resulted in the best fit of the calculated ensembles to the experimental ones for the tryptophan cage but in much poorer performance on the training set, suggesting that use of a small α-helical protein for extensive force-field calibration resulted in overfitting of the data for this protein at the expense of transferability. The optimized force field resulting from run 2 was found to fold 13 of the 14 tested α-helical proteins and one small α + β protein with the correct topologies; the average structures of 10 of them were predicted with accuracies of about 5 Å C<SUP>α</SUP> root-mean-square deviation or better. Test simulations with an additional set of 12 α-helical proteins demonstrated that this force field performed better on α-helical proteins than the previous parametrizations of UNRES. The proposed approach is applicable to any problem of maximum-likelihood parameter estimation when the contributions to the maximum-likelihood function cannot be evaluated at the experimental points and the dimension of the configurational space is too high to construct histograms of the experimental distributions.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jcisd8/2015/jcisd8.2015.55.issue-9/acs.jcim.5b00395/production/images/me

Role of the Wada test and functional magnetic resonance imaging in preoperative mapping of language and memory: two atypical cases

Połczyń,ska, Monika M.,Benjamin, Christopher F.A.,Moseley, Brian D.,Walshaw, Patricia,Eliashiv, Dawn,Vigil, Celia,Jones, Michael,Bookheimer, Susan Y. Informa UK (TaylorFrancis) 2015 Neurocase Vol.21 No.6