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Zhu Yinan,Lin Zuokang,Yu Haiyan,Yu Xiaohan,Dai Zhimin 한국원자력학회 2024 Nuclear Engineering and Technology Vol.56 No.5
Beam shaping assembly (BSA) is a vital component in Boron Neutron Capture Therapy (BNCT) for obtaining epithermal neutron beams. Several feasible designs of BSA for accelerator-based BNCT (AB-BNCT) neutron source are carried out based on neutrons by bombarding a natural lithium target with 10 mA, 2.8 MeV proton beams. The calculation results demonstrate that a thickness of 45 cm is appropriate for general moderators referring to the therapeutic parameter of Advanced Depth (AD). A series of optimizations are performed and two results are confirmed: One is that employing the configuration of MgF2 and FLUENTAL combined by 1:1 could improve the therapeutic rate (TR) of tumors at a depth of middle region, and the other one is that the TR of superficial tumors can be increased by adding a 5 cm thick boron-11 secondary moderator at the end of general moderators. As a result, an innovative conception of an adjustable moderator is recommended to BNCT. Compared to the MgF2 moderator with a fixed thickness of 45 cm, the TR value can be improved by a maximum of 47.7 % by using the adjustable moderator. Furthermore, the configuration of adjustable moderator has been designed with regulation method for treating tumors of different depths.
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한·중 확장 개념적 은유 대조 연구 - 코로나19를 중심으로 -
축일남(Zhu Yinan ),김성주(Kim, SeongJu) 돈암어문학회 2021 돈암어문학 Vol.40 No.-
본 연구의 목적은 한국어와 중국어에서 코로나19를 어떻게 개념화하고 있는지, 즉 한국인들과 중국인들이 현재 이 새로운 질병을 어떻게 이해하는지를 밝혀내어, 이 두 언어 사용자들의 코로나19에 대한 개념화 양상을 대조하는 것이다. 이 목적을 위해 본 연구에서는 Kövecses(2020)의 확장 개념적 은유 이론을 바탕으로 하고, 자료는 뉴스 데이터베이스를 활용하였다. 확장 개념적 은유 이론에서 제시한 네 가지 위계에 근거하여 해당 위계에 나타난 의미 요소의 사상 관계와 빈도수로 은유의 실현 양상을 분석하였다. 그 결과 질병과 같은 주관적이고 민감한 경험의 개념적 은유를 통해 한국어와 중국어에서 같은 화제를 표현할 경우 나타나는 인지적 기제의 이질성을 찾을 수 있다. 한국어는 중국어보다 전염병의 개념화에서 여행 은유를 선호한다. 중국어는 한국어보다 전쟁 은유를 선호한다. 본 연구는 개념적 은유에 대한 가장 최근 성과를 토대로 한국어와 중국어의 개념화 양상의 공통점과 차이점을 시도한 논의이다. The purpose of this study is to compare the conceptualization patterns of Korean and Chinese speakers by identifying how they conceptualize COVID-19, that is how Koreans and Chinese currently understand the new disease. To this purpose, this study uses the extended conceptual metaphor theory of Kövecses(2020) and studies practical use cases using the news database. According to the four bit orders proposed by the theory of extended conceptual metaphor, we try to analyze the implementation with the ideological relationship and frequency number of the meaning elements appearing in this bit order. The results show that the heterogeneity of the cognitive mechanisms could be found when expressing the same topic in Korean and Chinese through conceptual metaphors, like disease, which is subjective and sensitive. Based on the latest results of conceptual metaphor theory, we try to overcome previous studies on the composition of metaphor meanings and propose new comparative analysis, which can find the originality of this study.
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“过来/过去”与“건너오다/건너가다”的对比研究 ― 以概念隐喻层级性为中心
祝一男 ( Zhu Yinan ),韩容洙 ( Han Yongsu ) 중국어문연구회 2022 中國語文論叢 Vol.- No.108
The purpose of this study is to use the hierarchical theory of conceptual metaphor to analyze the cognitive rationale of the lexical meaning of “过来/过去” and “건너오다/건너가다”, and to help Korean learners grasp the basic semantics of “过来/过去” more easily by analyzing their similarities and differences, as well as to provide some insights for teaching Chinese as a foreign language. As a convergent verb, “过来/过去” appears as [V+오다/가다] in the elementary grammar teaching of compound convergent complement. From the observation of Korean Chinese textbooks, we found that the Korean translation of “过来/过去” is different. In fact, there are obvious differences in the spatial concept, i.e., the semantics of displacement, between “过来/过去” and “건너오다/건너가다”. From the analysis, it is clear that it is feasible to construct a metaphorical mapping hierarchical representation of displacement events through the imagery schemas formed in people’s daily experience to help us grasp the similarities and differences of paraphrased words between languages in a more intuitive way. This paper uses the latest theory to investigate and confirm some different conclusions, which are meaningful in a way. The author believes that if the translation of Korean lexical pairs of Chinese convergent verbs can be adjusted to a combination of cognitive-semantic interpretation and image schema in Korean Chinese textbooks, it can at least help to reduce bias.
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Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy
Liu Qun,Jiang Yinan,Zhu Lingyan,Qian Jieqi,Wang Chaoban,Yang Tianlun,Prasadan Krishna,Gittes George K.,Xiao Xiangwei 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
The adult pancreatic ductal system was suggested to harbor facultative beta-cell progenitors similar to the embryonic pancreas, and the appearance of insulin-positive duct cells has been used as evidence for natural duct-to-beta-cell reprogramming. Nevertheless, the phenotype and fate of these insulin-positive cells in ducts have not been determined. Here, we used a cell-tagging dye, CFDA-SE, to permanently label pancreatic duct cells through an intraductal infusion technique. Representing a time when significant increases in beta-cell mass occur, pregnancy was later induced in these CFDA-SE-treated mice to assess the phenotype and fate of the insulin-positive cells in ducts. We found that a small portion of CFDA-SE-labeled duct cells became insulin-positive, but they were not fully functional beta-cells based on the in vitro glucose response and the expression levels of key beta-cell genes. Moreover, these insulin-positive cells in ducts expressed significantly lower levels of genes associated with extracellular matrix degradation and cell migration, which may thus prevent their budding and migration into preexisting islets. A similar conclusion was reached through analysis of the Gene Expression Omnibus database for both mice and humans. Together, our data suggest that the contribution of duct cells to normal beta-cells in adult islets is minimal at best.
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JBRC: Jointly Balanced Routing and Charging Scheme for RF Energy Harvesting Wireless Sensor Networks
Chenyiming Wen,Bingqian Zhu,Yinan Zhu 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09
In radio frequency (RF) energy harvesting wireless sensor networks, employing a mobile charger (MC) is more cost-efficient and flexible to power the sensor nodes than deploying extensive stationary chargers. However, due to limited charging time of MC, the nodes’ residual energy distribution (i.e., energy balance degree) after charging will directly determine the lifetime of sensor networks. To promote the energy balance degree, two important problems required to solve are: how to determine the nodes’ routing scheme and how to schedule the MC to power the nodes. The two problems interact with each other. In this paper, we introduce a practical charging scenario, consider to combine the routing-based charging and charging-based routing, and propose a Jointly Balanced Routing and Charging (JBRC) scheme. Specifically, we propose a balanced routing strategy and a charging time allocation scheme, and iteratively jointly optimize them. Our goal is to achieve the energy balance in WSNs, i.e., maximizing the minimal residual energy among nodes. Additionally, the MC’s moving trajectory is selected and designed. From simulation experiments, we verify the superiority of our proposed JBRC scheme.
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