A Lexical and Syntactic Analysis System for Chinese Electronic Medical Record

Zhipeng Jiang,Xue Dai,Yi Guan,Fangfang Zhao 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.9

Lexical and syntactic analysis, including word segmentation, part-of-speech (POS) tagging, shallow parsing and full parsing, are essential for medical language processing (MLP). However, research on full parsing, even shallow parsing and POS tagging for Chinese electronic medical record (CEMR), has not been carried out because of the lack of annotated corpus on CEMR. In this paper, we built a corpus of 5,024 sentences from CEMR with word segmentation, POS tags and phrase tags, of them, 2,553 are annotated as full parsing trees. Inter-annotator agreement results: Chinese word segmentation (97.56%), POS tagging (93.34%), shallow parsing (96.5%), full parsing (91.22%). A lexical and syntactic analysis system for CEMR is developed and evaluated based on above corpus. Of its components, we proposed a joint model for word segmentation and POS tagging with the transformation-based error-driven model as correction postprocessing to alleviate the problem of error accumulation, the F1-score of word segmentation and POS tagging were 94.39% and 93.2%, respectively. A shallow parsing model under the framework of group learning we proposed was developed, which enriched word features by word embedding from large unlabeled CEMRs and achieved the F1-score of 96.3%. At last, we presented a state-of-art full parser combining the Berkeley parser and the Stanford parser to outperform the best single parser by 3.68%. The evaluation results show a substantial benefit to statistical machine learning models from the annotated CEMR. These works are the foundation for natural language processing (NLP) technologies applied to CEMR.

Quantitative analysis of carbon emissions in precision turning processes and industrial case study

Zhipeng Jiang,Dong Gao,Yong Lu,Linghao Kong,Zhendong Shang 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.1

With growing concerns regarding the global environment, the industrial sector has played a significant role; that is, it is responsible for consuming large amount of energy and resources, while simultaneously producing wastes and carbon dioxide. A quantitative calculation of carbon emission in the turning process is presented in this paper. A generic carbon emission system boundary based on exergy balance is proposed first to avoid blurred system boundaries or the omission of elements. Then, a carbon emission model (iERWC) is formed by converting energy consumption (E), resource depletion (R) and waste generation (W) to equivalent carbon emissions (C) based on information flow (i), which effectively solves the problem of quantifying the impact of the machining process on the environment. Finally, the model is verified by experiments, and a simulation analysis is carried out. Additionally, the influence rule of processing parameters on carbon emissions is analyzed, and the cutting parameter that produces the lowest carbon emission is given.

Analytical evaluation of the influence of vertical bridge deformation on HSR longitudinal continuous track geometry

Zhipeng Lai,Lizhong Jiang,Xiang Liu,Yuntai Zhang,Tuo Zhou 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.44 No.4

A high-speed railway (HSR) bridge may undergo long-term deformation due to the degradation of material stiffness, or foundation settlement during its service cycle. In this study, an analytical model is set up to evaluate the influence of this longterm vertical bridge deformation on the track geometry. By analyzing the structural characteristics of the HSR track-bridge system, the energy variational principle is applied to build the energy functionals for major components of the track-bridge system. By further taking into account the interlayer’s force balancing requirements, the mapping relationship between the deformation of the track and the one of the bridge is established. In order to consider the different behaviors of the interlayers in compression and tension, an iterative method is introduced to update the mapping relationship. As for the validation of the proposed mapping model, a finite element model is created to compare the numerical results with the analytical results, which show a good agreement. Thereafter, the effects of the interlayer’s different properties of tension and compression on the mapping deformations are further evaluated and discussed.

A negative stiffness inerter system (NSIS) for earthquake protection purposes

Zhipeng Zhao,Qingjun Chen,Ruifu Zhang,Yiyao Jiang,Chao Pan 국제구조공학회 2020 Smart Structures and Systems, An International Jou Vol.26 No.4

The negative stiffness spring and inerter are both characterized by the negative stiffness effect in the force-displacement relationship, potentially yielding an amplifying mechanism for dashpot deformation by being incorporated with a series tuning spring. However, resisting forces of the two mechanical elements are dominant in different frequency domains, thus leading to necessary complementarity in terms of vibration control and the amplifying benefit. Inspired by this, this study proposes a Negative Stiffness Inerter System (NSIS) as an earthquake protection system and developed analytical design formulae by fully utilizing its advantageous features. The NSIS is composed of a sub-configuration of a negative stiffness spring and an inerter in parallel, connected to a tuning spring in series. First, closed-form displacement responses are derived for the NSIS structure, and a stability analysis is conducted to limit the feasible domains of NSIS parameters. Then, the dual advantageous features of displacement reduction and the dashpot deformation amplification effect are revealed and clarified in a parametric analysis, stimulating the establishment of a displacement-based optimal design framework, correspondingly yielding the design formulae in analytical form. Finally, a series of examples are illustrated to validate the derived formulae. In this study, it is confirmed that the synergistic incorporation of the negative stiffness spring and the inerter has significant energy dissipation efficiency in a wide frequency band and an enhanced control effect in terms of the displacement and shear force responses. The developed displacement-based design strategy is suitable to utilize the dual benefits of the NSIS, which can be accurately implemented by the analytical design formulae to satisfy the target vibration control with increased energy dissipation efficiency.

Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs

Zhipeng Yao,Xiaochun Jiang,Hong Yao,Yafeng Wu,Fan Zhang,Cheng Wang,Chenxue Qi,Chenhui Zhao,Zeyu Wu,Min Qi,Jia Zhang,Xiaoxiang Cao,Zhichun Wang,Fei Wu,Chengyun Yao,Songqin Liu,Shizhang Ling,Hongping Xi 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

Background: Glioblastoma multiforme (GBM) is a fatal malignant primary brain tumor in adults. The therapeutic efficacy of chemotherapeutic drugs is limited due to the blood-brain barrier (BBB), poor drug targeting, and short biological half-lives. Multifunctional biomimetic nanodrugs have great potential to overcome these limitations of chemotherapeutic drugs. Methods: We synthesized and characterized a biomimetic nanodrug CMS/PEG-DOX-M. The CMS/PEG-DOX-M effectively and rapidly released DOX in U87 MG cells. Cell proliferation and apoptosis assays were examined by the MTT and TUNEL assays. The penetration of nanodrugs through the BBB and anti-tumor efficacy were investigated in the orthotopic glioblastoma xenograft models. Results: We showed that CMS/PEG-DOX-M inhibited cell proliferation of U87 MG cells and effectively induced cell apoptosis of U87 MG cells. Intracranial antitumor experiments showed that free DOX hardly penetrated the BBB, but CMS/PEG-DOX-M effectively reached the orthotopic ntracranial tumor through the BBB and significantly inhibited tumor growth. Immunofluorescence staining of orthotopic tumor tissue sections confirmed that nanodrugs promoted apoptosis of tumor cells. This study developed a multimodal nanodrug treatment system with the enhanced abilities of tumor-targeting, BBB penetration, and cancer-specific accumulation of chemotherapeutic drugs by combining chemotherapy and photothermal therapy. It can be used as a flexible and effective GBM treatment system and it may also be used for the treatment of other central nervous systems (CNS) tumors and extracranial tumors.

Phase-field simulation of radiation-induced bubble evolution in recrystallized U-Mo alloy

Yanbo Jiang,Yong Xin,Wenbo Liu,Zhipeng Sun,Ping Chen,Dan Sun,Mingyang Zhou,Xiao Liu,Di Yun 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.1

In the present work, a phase-field model was developed to investigate the influence of recrystallizationon bubble evolution during irradiation. Considering the interaction between bubbles and grain boundary(GB), a set of modified Cahn-Hilliard and Allen-Cahn equations, with field variables and order parametersevolving in space and time, was used in this model. Both the kinetics of recrystallization characterized inexperiments and point defects generated during cascade were incorporated in the model. The bubbleevolution in recrystallized polycrystalline of UeMo alloy was also investigated. The simulation resultsshowed that GB with a large area fraction generated by recrystallization accelerates the formation andgrowth of bubbles. With the formation of new grains, gas atoms are swept and collected by GBs. Thesimulation results of bubble size and distribution are consistent with the experimental results.

Experimental investigation of impact-sliding interaction and fretting wear between tubes and anti-vibration bars in steam generators

Guo, Kai,Jiang, Naibin,Qi, Huanhuan,Feng, Zhipeng,Wang, Yang,Tan, Wei Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.6

The tubes in a heat exchanger, such as a steam generator (SG), are subjected to crossflow, and interaction between tubes and supports can happen, which can cause fretting wear of tubes. Although many experiments and models have been established, some detailed mechanisms are still not sufficiently clear. In this work, more attention is paid to obtain the regulation of impact and sliding in the complex process and many factors, such as excitation forces and clearances. The responses and contact forces were analyzed to obtain clear understanding of the influences of these factors. Room temperature tests in the air were established. The results show that the effect of clearance on the normal work rate is not monotonous and instead has two peaks. The force ratio can influence the normal work rate by changing the distribution of contact angles, which can result in higher sliding in the contact process. Fretting wear tests are conducted, and the wear surfaces are analyzed by a scanning electron microscope (SEM) and energy dispersive X-ray spectrometer (EDX). The results of this work can serve as a reference for impactsliding contact analysis between AVBs and tubes in steam generators.

A Novel Three-Phase Four-Wire Grid-Connected Synchronverter that Mimics Synchronous Generators

Qian Tan,Zhipeng Lv,Bei Xu,Wenqian Jiang,Xin Ai,Qingchang Zhong 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.6

Voltage and frequency stability issues occur in existing centralized power system due to the high penetration of renewable energy sources, which decrease grid absorptive capacity of them. The grid-connected inverter that mimics synchronous generator characteristics with inertia characteristic is beneficial to electric power system stability. This paper proposed a novel three-phase four-wire grid-connected inverter with an independent neutral line module that mimics synchronous generators. A mathematical model of the synchronous generator and operation principles of the synchronverter are introduced. The main circuit and control parameters design procedures are also provided in detail. A 10 ㎾ prototype is built and tested for further verification. The primary frequency modulation and primary voltage regulation characteristics of the synchronous generator are emulated and automatically adjusted by the proposed circuit, which helps to supports the grid.

Evaluation of optimal ground motion intensity measures of high-speed railway train running safety on bridges during earthquakes

Xiang Liu,Lizhong Jiang,Ping Xiang,Yulin Feng,Zhipeng Lai,Xiaoyun Sun 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.81 No.2

Due to the large number of railway bridges along China's high-speed railway (HSR) lines, which cover a wide area with many lines crossing the seismic zone, the possibility of a HSR train running over a bridge when an earthquake occurs is relatively high. Since the safety performance of the train will be threatened, it is necessary to study the safety of trains running over HSR bridges during earthquakes. However, ground motion (GM) is highly random and selecting the appropriate groundmotion intensity measures (IMs) for train running safety analysis is not trivial. To deal this problem, a model of a coupled trainbridge system under seismic excitation was established and 104 GM samples were selected to evaluate the correlation between 16 different IMs and train running safety over HSR bridges during earthquakes. The results show that spectral velocity (SvT1) and displacement (SdT1) at the fundamental period of the structure have good correlation with train running safety for mediumand long-period HSR bridges, and velocity spectrum intensity (VSI) and Housner intensity (HI) have good correlation for a wide range of structural periods. Overall, VSI and HI are the optimal IMs for safety analysis of trains running over HSR bridges during earthquakes. Finally, based on VSI and HI, the IM thresholds of an HSR bridge at different speed were analyzed.

Transmission Line Modeling and Algorithm Analysis Considering Parameter Asymmetry and Transient High-frequency Components

Mo Shixun,Lv Zhipeng,Han Kunlun,Yuan Rongji,Yang Hao,Jiang Kunping,Liang Zhenshen 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.2

When the power system is disturbed or the operation mode is changed, the electromagnetic transient process will occur, which will lead to the high frequency transient component and aff ect the protection and control of the power system. Therefore, attention should be paid to the analysis of high-frequency transient components when modeling and analyzing the system model. In view of the fact that the symmetrical-component theory is not suitable for asymmetric transmission lines and the phasor method is not suitable for transient analysis and calculation, this paper uses the phase coordinate approach and Laplace transform to derive the node voltage equation of three-phase π type transmission lines in frequency domain, which can be used to calculate the transient response of transmission lines caused by the change of operation mode or disturbance. And vectorized NILT is used to calculate the time domain solution, which greatly improves the calculation speed. The calculated results are basically consistent with those of ATP-EMTP, and can fully refl ect the transient characteristics. This method lays a foundation for analyzing the infl uence of high frequency transient components on power system and fault analysis considering transient process.