The Effect of Electron-withdrawing Group Functionalization on Antibacterial and Catalytic Activity of Palladium(II) Complexes

Zhi-Qiang Feng,Xiao-Li Yang,Yuan-Feng Ye,Lin-Yun Hao 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

The design, synthesis, and structural characterization of two new palladium complexes based on Schiff base ligands is reported; [Pd(L1)2] (1) and [Pd(L2)2] (2), [HL1 = 2-((E)-(2,6-diethylphenylimino)methyl)-4,6- dibromophenol, L2 = (E)-N-benzylidene-2,6-diethylbenzenamine], which are obtained by functionalizing Schiff base ligands with or without electron-withdrawing groups. Both compounds are mononuclear structures. Comparisons are made to the compounds 1 and 2 to analyze and understand the effect of electron-withdrawing groups. Antibacterial activity studies indicate the electron-withdrawing groups on Schiff base ligands enhance antibacterial activity. Catalytic activity, however, is reduced due to the enhanced steric-hindrance of the electron-withdrawing groups. Electronic absorption and emission properties of HL1, L2, 1 and 2 are also reported.

Expression of Ki67 in Papillary Thyroid Microcarcinoma and its Clinical Significance

Zhou, Yuan,Jiang, Hong-Gang,Lu, Ning,Lu, Bo-Hao,Chen, Zhi-Heng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4

Purpose: To investigate the expression of Ki67 protein in papillary thyroid microcarcinoma(PTMC), and to analyze its clinical significance. Materials and Methods: Ki67 protein expression was evaluated in the tissues of 108 human PTMC and 50 other benign papillary hyperplasia of thyroid specimens using immunohistochemistry. Results: The expression intensity of Ki67 in PTMC and benign papillary hyperplasia of thyroid specimens were $1.45{\pm}1.83%$ and $0.46{\pm}0.46%$.The positive expression rates were 46.3% and 14%. There were significant differences between these two groups (p<0.01). There was no significant variation of the expression intensity and positive expression rates of Ki67 in PTMC with gender, age, position of the tumor and the level of TSH pre-operation (p>0.05), but these parameters varied with tumor size, invasion by membrane and cervical lymph node metastasis (p<0.05 or p<0.01). Conclusions: The expression of Ki67 in PTMC was related to tumor size, invasion by membrane and cervical lymph node metastasis, and could be the important indicator for judging clinical progress and estimating prognosis.

The Effect of Electron-withdrawing Group Functionalization on Antibacterial and Catalytic Activity of Palladium(II) Complexes

Feng, Zhi-Qiang,Yang, Xiao-Li,Ye, Yuan-Feng,Hao, Lin-Yun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

The design, synthesis, and structural characterization of two new palladium complexes based on Schiff base ligands is reported; $[Pd(L1)_2]$ (1) and $[Pd(L2)_2]$ (2), [HL1 = 2-((E)-(2,6-diethylphenylimino)methyl)-4,6-dibromophenol, L2 = (E)-N-benzylidene-2,6-diethylbenzenamine], which are obtained by functionalizing Schiff base ligands with or without electron-withdrawing groups. Both compounds are mononuclear structures. Comparisons are made to the compounds 1 and 2 to analyze and understand the effect of electron-withdrawing groups. Antibacterial activity studies indicate the electron-withdrawing groups on Schiff base ligands enhance antibacterial activity. Catalytic activity, however, is reduced due to the enhanced steric-hindrance of the electron-withdrawing groups. Electronic absorption and emission properties of HL1, L2, 1 and 2 are also reported.

Overexpression of the maize ZmAMT1;1a gene enhances root ammonium uptake efficiency under low ammonium nutrition

Yang Zhao,Zhi Liu,Fengying Duan,Xia An,Xiangguo Liu,Dongyun Hao,Riliang Gu,Zhangkui Wang,Fanjun Chen,Lixing Yuan 한국식물생명공학회 2018 Plant biotechnology reports Vol.12 No.1

High-affinity ammonium uptake in maize roots is mainly mediated by AMT1-type ammonium transporters ZmAMT1;1a and ZmAMT1;3, but whether the increased expression of ZmAMTs genes is able to enhance ammonium uptake capacity and subsequently improves overall nitrogen use efficiency remains to be elucidated. In this work, ZmAMT1;1a-overexpression transgenic maize plants were generated with the elevated levels of transcripts and proteins, and phenotypically analyzed together with wild-type plants grown in nutrient solution under two regimes of ammonium supply. Under low ammonium nutrition (0.04 mM), in relative to wild-type plants, the maize transgenic lines showed an approximately 17% increases in the high-affinity ammonium uptake capacity of roots as revealed by 15N-labeled ammonium influx assay and further contributed to about 7% increases in the total nitrogen uptake at the whole plant level. By contrast, when ammonium was supplied in high amounts (1 mM), wild-type plants expressed higher levels of ZmAMT1;1a, but exhibited a lower ammonium uptake capacity in roots. Furthermore, the transgenic maize line accumulated more amounts of ZmAMT1;1a protein, but did not translate into an enhanced ammonium acquisition, suggesting a possible post-translational down-regulation of ZmAMT1;1a by high ammonium. This study proved the possibility to enhance ammonium acquisition by elevating ZmAMTs expression in maize roots and provided an effective transgenic approach on developing high nitrogen use efficient maize cultivars.

Vibration Rapid Analysis and Comparison of Motor Support in Container Crane’s Machine Room with Single Degree of Freedom and Finite Element Method Based on Visual Basic

Lu Kai-liang,Ye Hao,Qiu Hui-qing,Zhang Wei-guo,Hao Zhi-yong,Liu Yuan 보안공학연구지원센터(IJGDC) 2013 International Journal of Grid and Distributed Comp Vol.6 No.4

Production of isophthalic acid from m-xylene oxidation under the catalysis of the H3PW12O40/carbon and cobalt catalytic system

Xiang-li Long,Zhi-hao Wang,San-qiang Wu,Shi-ming Wu,Hai-feng Lv,Wei-kang Yuan 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.1

Isophthalic acid (IPA) is commercially produced from m-xylene oxidation with the catalysis of thehomogeneous Co–Mn–Br catalyst system. In this study, a catalytic system consisting of HPW/C and Co(II)has been put forward to oxidize m-xylene (MX) to IPA. The experimental results prove that the HPW/Cand Co catalytic system is capable of catalyzing the oxidation of MX to IPA, which can obtain a higher MXconversion and IPA concentration than the homogeneous H3PW12O40/Co(OAc)2/Mn(OAc)2 catalyticsystem. The heterogeneous catalytic system is also advantageous over the homogeneous catalyticsystem in the inhibition of the oxidation of acetic acid and IPA. The optimal amount of phosphotungsticacid supported on carbon is 7.5% (wt). The best dosage of HPW/C is 15 g l-1. The optimum Co(II)concentration in the catalytic system for IPA production is 0.064% (wt). The best HPW/C activationtemperature is 220℃ .

Enhanced Metal-Insulator Transition Performance in Scalable Vanadium Dioxide Thin Films Prepared Using a Moisture-Assisted Chemical Solution Approach

Liang, Weizheng,Gao, Min,Lu, Chang,Zhang, Zhi,Chan, Cheuk Ho,Zhuge, Lanjian,Dai, Jiyan,Yang, Hao,Chen, Chonglin,Park, Bae Ho,Jia, Quanxi,Lin, Yuan American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.9

<P>Vanadium dioxide (VO<SUB>2</SUB>) is a strong-correlated metal-oxide with a sharp metal-insulator transition (MIT) for a range of applications. However, synthesizing epitaxial VO<SUB>2</SUB> films with desired properties has been a challenge because of the difficulty in controlling the oxygen stoichiometry of VO<SUB><I>x</I></SUB>, where <I>x</I> can be in the range of 1 < <I>x</I> < 2.5 and V has multiple valence states. Herein, a unique moisture-assisted chemical solution approach has been developed to successfully manipulate the oxygen stoichiometry, to significantly broaden the growth window, and to significantly enhance the MIT performance of VO<SUB>2</SUB> films. The obvious broadening of the growth window of stoichiometric VO<SUB>2</SUB> thin films, from 4 to 36 °C, is ascribed to a self-adjusted process for oxygen partial pressure at different temperatures by introducing moisture. A resistance change as large as 4 orders of magnitude has been achieved in VO<SUB>2</SUB> thin films with a sharp transition width of less than 1 °C. The much enhanced MIT properties can be attributed to the higher and more uniform oxygen stoichiometry. This technique is not only scientifically interesting but also technologically important for fabricating wafer-scaled VO<SUB>2</SUB> films with uniform properties for practical device applications.</P> [FIG OMISSION]</BR>

Determination of equivalent blasting load considering millisecond delay effect

Song, Zhan-Ping,Li, Shi-Hao,Wang, Jun-Bao,Sun, Zhi-Yuan,Liu, Jing,Chang, Yu-Zhen Techno-Press 2018 Geomechanics & engineering Vol.15 No.2

In the analysis of the effects of rock tunnel blasting vibration on adjacent existing buildings, the model of simplified equivalent load produces higher calculation result of vibration, due to the lack of consideration of the millisecond delay effect. This paper, based on the static force equivalence principle of blasting load, proposes a new determination method of equivalent load of blasting vibration. The proposed method, based on the elastic-static force equivalence principle of stress wave, equals the blasting loads of several single blastholes in the same section of millisecond blasting to the triangle blasting load curve of the exploded equivalent elastic boundary surface. According to the attenuation law of stress wave, the attenuated equivalent triangle blasting load curve of the equivalent elastic boundary is applied on the tunnel excavation contour surface, obtaining the final applied equivalent load. Taking the millisecond delay time of different sections into account, the time-history curve of equivalent load of the whole section applied on the tunnel excavation contour surface can be obtained. Based on Sailing Tunnel with small spacing on Sanmenxia-Xichuan Expressway, an analysis on the blasting vibration response of the later and early stages of the tunnel construction is carried out through numerical simulation using the proposed equivalent load model considering millisecond delay effect and the simplified equivalent triangle load curve model respectively. The analysis of the numerical results comparing with the field monitoring ones shows that the calculation results obtained from the proposed equivalent load model are closer to the measured ones and more feasible.

Rapid Movement of Water Droplets on the Hydrophobic Surface of ZnO Nanorod Array Impregneted by Lubricant

Xue-Wei Wang,Shen-Ao Zhang,Cui Guo,Zhi-hao Yuan 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.4

In this paper, it is described that the motion of water droplets on the hydrophobic surface of ZnO nanorod array impregnated lubricant, is called slippery liquid-infused porous surface (SLIPS). The energy gradient required to induce the motion of the droplets is created on the boundary of superhydrophobic ZnO nanorod array and SLIPS. Because of the lower viscous force of SLIPS, the water droplet can rapidly move for longer distance on the surface. In view of changing the release distance of water droplet, the mechanism for the rapid movement is discussed. The results indicate that the movement distance of water droplet markedly increases with the increasing of the release distance. Because the potential energy of the height is converted into kinetic energy, the water droplet intensively collides the interface between ZnO nanorod array and SLIPS. This impact makes the water droplet distort, which enhances the driving force. These new findings will not only deepen our understanding of the relationship between surface structure and dynamic wetting properties, but also afford the new notion and beneficial reference for designing liquid droplet transportation devices in micro-fluidic systems.

Abnormal resistanceetemperature characteristic of the melting Bi nanowires

Xue-wei Wang,Chao Ma,Bing-cheng Fang,Zhi-hao Yuan 한국물리학회 2014 Current Applied Physics Vol.14 No.11

There are no reports about the electronic transport behavior of the melting metal nanostructures because the morphology of nanostructures cannot be kept under the melting condition. Here, the electronic properties of the melting Bi nanowires are investigated using the pore confinement of anodic aluminum oxide template. The results indicate that with the increase of temperature the resistance of Bi nanowires has a transition from the positive temperature coefficient of resistance before fusion to the negative one after fusion. Moreover, as the temperature gradually increases, the resistance of the melting Bi nanowires rapidly decreases at first, and then tardily decreases. This research provides fundamental and valuable information for exploring and designing the new electronic devices under the high temperature.