Effects of Green Tea on Blood Pressure and Hypertension-induced Cardiovascular Damage in Spontaneously Hypertensive Rat

Yue-Rong Liang,Shi-Cheng Ma,Xin-Qiang Zheng,Jing-Yi Xu,Ming-Yan Wu,Yi-Wen Luo,Xian-Yang Luo,Jian-Liang Lu 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.1

Three groups of spontaneously hypertensive rats were administered by gavage with distilled water (control group), low-dose green tea (LGT, 0.2 g/kg BW·day) and high-dose green tea (HGT, 1.0 g/kg BW·day) for 4 weeks,during which systolic blood pressure (SBP) was measured weekly by non-invasive tail-cuff method. At the end of experiment, left ventricular hypertrophy index (LHVI) and plasma biochemical indicators were determined, and ultrastructures of myocardium and aortic vascular smooth muscle cells were observed by transmission electron microscopy (TEM). The results show that green tea gavage suppressed the increase in SBP, along with decline in levels of plasma nitric oxide, aldosterone, malondialdehyde, and LHVI, but increased levels of plasma creatinine, calcitonin gene-related peptide, and glutathione peroxidase in a dose dependant manner. Green tea had no effect on plasma total cholesterol. TEM shows that green tea gavage protected mitochondria of left ventricular myocardium and aortic vascular smooth muscle cells from damage.

More precise determination of V_cb & V_ub and direct CP violation in charmless B decays

Yue-liang Wu,Yu-Feng Zhou,YWhen-Yu Wang 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.2

More precise extractions on the two important CKM matrix elements jVcbj and jVubj are presented up to 1=m2 Q corrections, based on the complete heavy-quark eective eld theory (HQEFT) of QCD. The HQEFT as a large component QCD provides us with a complete theoretical framework for correctly and systematically evaluating the subleading and higher-order contributions in 1=mQ expansion of heavy quarks. A global analysis on charmless B decays is made, based on the isospin and SU(3) avor symmetry. An isospin relation is found to be very useful for studying SU(3) symmetry-breaking eects of strong phases and exploring new types of electroweak penguin eects. The direct CP violation in charmless B decays is predicted, and its precise measurement is helpful either for testing SU(3) symmetry breaking eects of strong phases or for probing new physics beyond standard model.

CO2 capture and preparation of spindle-like CaCO3 crystals for papermaking using calcium carbide residue waste via an atomizing approach

Liang Ma,Tingyu Yang,Yu Wu,Xiaoqing Yue,Jinrong Yang,Shuai Zhang,Qiang Li,Jianbin Zhang 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.9

Spindle-like CaCO3 crystals with controllable sizes for papermaking were successfully prepared using CO2 (8% CO2/N2 mixture gas) and calcium carbide residue (CCR) waste, a by-product of acetylene gas and polyvinyl chloride production, as the raw materials by an atomization method at room temperature. The influences of solution concentration, reaction temperature, and gas/liquid flow rate ratios on the properties of the CaCO3 crystal were systematically investigated, and a possible atomization mechanism was proposed. The size of the as-prepared CaCO3 crystal with pure calcite phase was turned from 4.71×4.02 μm to 1.82×1.12 μm by adjusting the reaction conditions. The application of the as-prepared CaCO3 crystals from CCR waste as a filler for papermaking was explored. The R475 blue light whiteness of paper was increased from 77.3 to 80.6 with 11.4% CaCO3 crystals

Study of the Optimal Film Structure by Using Conventional Elipsometry

Liang-Yao Chen,Ming-Yu Sheng,Yun-Hua Wu,Yuan Zhao,Yue-Rui Chen,Yu-Xiang Zheng 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.2

The optimal film structure affected by the space effect has been studied for SiO2 film samples deposited onto Si wafers by using the e-beam evaporation method. The ellipsometric data were measured at different incidence angles and in the 300-800-nm wavelength range. In the range where the phase delay δ is close to π, the film thickness deduced from the conventional ellipsometry model varied with the phase delay. The optimal SiO2 film-thickness was achieved with a modified ellipsometric model, including the space effect. The results given in this work can generally be applied to other optical measurement methods used to study film structures.

Design and Implementation of Energy Saving Controller for Air-Conditioner in Building

Liang Zhao,Jili Zhang,Yue Shen,Wenyan Wu 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.8

This paper has completed the hardware design of STM32F103 system circuit, infrared code learning module, human body infrared sensor module, indoor temperature and humidity sensor module, completes the software design of learning air conditioning remote control code, indoor temperature and humidity sensor module, also completes the energy-saving controller hardware and software debugging. Finally, this paper takes split type air conditioning units in a conference room as the control object (including indoor lighting system) to complete the energy-saving controller in air conditioner electrical system design, installation and debugging, completes the air conditioning start-stop and infrared temperature control code learning test. The test results show that energy-saving controller has realized infrared automatic perception of human activity, machine start-stop code self-learning and temperature settings and other functions.

Non-cooperative interference radio localization with binary proximity sensors

( Qihui Wu ),( Liang Yue ),( Long Wang ),( Guoru Ding ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.9

Interference can cause serious problems in our daily life. Traditional ways in localizing a target can`t work well when it comes to the source of interference for it may take an uncooperative or even resistant attitude towards localization. To tackle this issue, we take the BPSN (Binary Proximity Sensor Networks) and consider a passive way in this paper. No cooperation is needed and it is based on simple sensor node suitable for large-scale deployment. By dividing the sensing field into different patches, when enough patches are formed, good localization accuracy can be achieved with high resolution. Then we analyze the relationship between sensing radius and localization error, we find that in a finite region where edge effect can`t be ignored, the trend between sensing radius and localization error is not always consistent. Through theoretical analysis and simulation, we explore to determine the best sensing radius to achieve high localization accuracy.

Exploring differentially expressed genes related to metabolism by RNA-Seq in porcine embryonic fibroblast after insulin treatment

Yingjuan Liang,Jinpeng Wang,Xinyu Li,Shuang Wu,Chaoqian Jiang,Yue Wang,Xuechun Li,Zhong-Hua Liu,Yanshuang Mu 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.6

Background: Insulin regulates glucose homeostasis and has important effects on metabolism, cell growth, and differentiation. Depending on the cell type and physiological context, insulin signal has specific pathways and biological outcomes in different tissues and cells. For studying the signal pathway of insulin on glycolipid metabolism in porcine embryonic fibroblast (PEF), we used high-throughput sequencing to monitor gene expression patterns regulated by insulin. Objectives: The goal of our research was to see how insulin affected glucose and lipid metabolism in PEFs. Methods: We cultured the PEFs with the addition of insulin and sampled them at 0, 48, and 72 h for RNA-Seq analysis in triplicate for each time point. Results: At 48 and 72 h, 801 and 1,176 genes were differentially expressed, respectively. Of these, 272 up-regulated genes and 264 down-regulated genes were common to both time points. Gene Ontology analysis was used to annotate the functions of the differentially expressed genes (DEGs), the biological processes related to lipid metabolism and cell cycle were dominant. And the DEGs were significantly enriched in interleukin-17 signaling pathway, phosphatidylinositol-3-kinase-protein kinase B signaling pathway, pyruvate metabolism, and others pathways related to lipid metabolism by Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Conclusions: These results elucidate the transcriptomic response to insulin in PEF. The genes and pathways involved in the transcriptome mechanisms provide useful information for further research into the complicated molecular processes of insulin in PEF.

Protective association of Klotho rs495392 gene polymorphism against hepatic steatosis in non-alcoholic fatty liver disease patients

Wen-Yue Liu,Xiaofang Zhang,Gang Li,Liang-Jie Tang,Pei-Wu Zhu,Rafael S. Rios,Kenneth I. Zheng,Hong-Lei Ma,Xiao-Dong Wang,Qiuwei Pan,Robert J. de Knegt,Luca Valenti,Mohsen Ghanbari,Ming-Hua Zheng 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.2

Background/Aims: Non-alcoholic fatty liver disease (NAFLD) is closely associated with metabolic dysfunction. Among the multiple factors, genetic variation acts as important modifiers. Klotho, an enzyme encoded by the klotho (KL) gene in human, has been implicated in the pathogenesis of metabolic dysfunctions. However, the impact of variants in KL on NAFLD risk remains poorly understood. The aim of this study was to investigate the impact of KL rs495392 C>A polymorphism on the histological severity of NAFLD. Methods: We evaluated the impact of the KL rs495392 polymorphism on liver histology in 531 Chinese with NAFLD and replicated that in the population-based Rotterdam Study cohort. The interactions between the rs495392, vitamin D, and patatin-like phospholipase domain containing 3 (PNPLA3) rs738409 polymorphism were also analyzed. Results: Carriage of the rs495392 A allele had a protective effect on steatosis severity (odds ratio [OR], 0.61; 95% confidence interval [CI], 0.42–0.89; P=0.010) in Chinese patients. After adjustment for potential confounders, the A allele remained significant with a protective effect (OR, 0.66; 95% CI, 0.45–0.98; P=0.040). The effect on hepatic steatosis was confirmed in the Rotterdam Study cohort. Additional analysis showed the association between serum vitamin D levels and NAFLD specifically in rs495392 A allele carriers, but not in non-carriers. Moreover, we found that the rs495392 A allele attenuated the detrimental impact of PNPLA3 rs738409 G allele on the risk of severe hepatic steatosis. Conclusions: The KL rs495392 polymorphism has a protective effect against hepatic steatosis in patients with NAFLD.

Roles of Immunohistochemical Staining in Diagnosing Pulmonary Squamous Cell Carcinoma

Yan, Yue,Zhang, Ya-Xiong,Fang, Wen-Feng,Kang, Shi-Yang,Zhan, Jian-Hua,Chen, Nan,Hong, Shao-Dong,Liang, Wen-Hua,Tang, Yan-Na,He, Da-Cheng,Wu, Xuan,Zhang, Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

Background: Differentiating morphologic features based on hematoxylin-eosin (HE) staining is the most common method to classify pathological subtypes of non-small-cell lung cancer (NSCLC). However, its accuracy and inter-observer reproducibility in pathological diagnosis of poorly differentiated NSCLC remained to be improved. Materials and Methods: We attempted to explore the role of immunohistochemistry (IHC) staining in diagnosing pulmonary squamous cell carcinoma (SQCC) with poorly differentiated features by HE staining or with elevated serum adenocarcinoma-specific tumor markers (AD-TMs). We also compared the difference of epidermal growth factor receptor (EGFR) mutation rate between patients with confirmed SQCC and those with revised pathological subtype. Logistic regression analyses were used to test the association between different factors and diagnostic accuracy. Results: A total of 132 patients who met the eligible criteria and had adequate specimens for IHC confirmation were included. Pathological revised cases in poor differentiated subgroup, biopsy samples and high-level AD-TMs cases were more than those with high/moderate differentiation, surgical specimens and normal-level AD-TMs. Moreover, biopsy sample was a significant factor decreasing diagnostic accuracy of pathological subtype (OR, 4.037; 95% CI 1.446-11.267, p=0.008). Additionally, EGFR mutation rate was higher in patients with pathological diagnostic changes than those with confirmed SQCC (16.7% vs 4.4%, p=0.157). Conclusions: Diagnosis based on HE staining only might cause pathological misinterpretation in NSCLC patients with poor differentiation or high-level AD-TMs, especially those with biopsy samples. HE staining and IHC should be combined as pathological diagnostic standard. The occurrence of EGFR mutations in pulmonary SQCC might be overestimated.

A Review on Microbial Decaffeination

Hui-Shi Wu,Xin-Qiang Zheng,Yue-Rong Liang,Jian-Hui Ye,Jian-Liang Lu 한국차학회 2015 한국차학회지 Vol.- No.S

Exclusive exposure of caffeine might bring some adverse effects to human health, and cause some risks to environment. Microbial decaffeination might be a new alternative approach because of its high specificity and efficiency. Many studies revealed that several microorganisms can degrade caffeine, including genera Alcaligenes,Rhodococcus, Klebsiella, Acinetobacter, Enterobacter, Stenotrophomonas and Pseudomonas. Biodegradation of caffeine can be significantly influenced by temperature, pH, aeration rate and initial caffeine concentration of the incubation. There are two main pathways of caffeine biodegradation: C-8 oxidation and N-demethylation, while N-demethylation is the general catabolism pathway in bacteria. Application of microbial decaffeination has also been discussed in this review.