Effect of Substrate Temperature on Microstructure of TiO₂ Films Deposited by Glancing-angle Sputtering

Yu Cong Chen,Yasushi Inoue,Osamu Takai 한국표면공학회 2023 한국표면공학회 학술발표회 초록집 Vol.2023 No.11-1

Association between Pax8-PPARγ1 Rearrangement and Follicular Thyroid Cancer: a Meta-Analysis

Li, Hang-Yu,Xie, Zhi-Hao,Xu, Cong-Hui,Pu, Mei-Ling,Chen, Zi-Yan,Yu, Miao,Wang, Heng-Shu,Zhou, Chen-Ming,Pu, Chao-Yu,Liu, Wei Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9

Background: Pax8 and peroxisome proliferator-activated receptor gamma 1 gene (Pax8-$PPAR{\gamma}1$) are important factors in tumors. Several studies have suggested that follicular thyroid cancer may arise from Pax8- $PPAR{\gamma}1$ rearrangement. In order to have a better understanding of the association between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer, we conducted the presenmt meta-analysis. Materials and Methods: The information was extracted from PubMed, EMBASE and Web of Science. Statistic analysis was performed with Stata12.0 software. Odds ratios (ORs) were calculated using a fixed-effects model. We also performed heterogeneity and publication bias analyses. Results: Nine studies including 198 follicular thyroid cancer patients and 268 controls were considered eligible. The frequency of Pax8-$PPAR{\gamma}1$ rearrangement was significantly higher in the follicular thyroid cancer group than in the control group, with a pooled OR of 6.63 (95%CI=3.50-12.7). In addition, through subgroup analysis, the OR between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer was 6.04 (95%CI = 3.18-11.5) when using benign tumor tissues as controls. The OR for the method subgroup was 9.99 (95% CI =4.86-20.5) in the RT-PCR. Conclusions: The final results demonstrated that Pax8-$PPAR{\gamma}1$ rearrangement has significant association with follicular thyroid cancer.

Effects of E-commerce Terminal Logistics Service Quality on Rural Residents' Online Purchasing Behavior — Case study: Jilin Province in China

Yu-cong Sun,Shi-yong Piao,Jin-tao Chen,Bobah Brillant Sisang,Jong-in Lee 한국국제농업개발학회 2021 韓國國際農業開發學會誌 Vol.33 No.4

농촌 종점 물류는 농촌 주민들의 온라인 쇼핑에 영향을 주는 중요한 요인임. 농촌 인터넷 쇼핑의 서비스 품질은 양호한 종점 물류 배송과 지원이 필요함. 농촌 이커머스의 발전에 의 하여 농촌 주민들이 서비스의 품질에 대한 기대치도 높아지고 있음. 본 연구에서는 이커머스 만족도를 통한 농촌 종점 물류 서비스 품질이 농촌 주민의 온라인 구매행위에 어떠한 영향 미치는지 검토하고, 농촌 종점 물류 서비스의 발전을 위한 개 선 및 발전전략을 제시하였음. 본 연구에서는 구조방정식모델 (SEM)과 온충린의 매개효과 테스트를 적용하여 분석하였음. 1. 신뢰성과 서비스 편의성은 만족도에 긍정적 영향을 미치며, 원가절약은 만족도에 부정적 영향을 미침. 2. 만족도는 인터넷 쇼핑에 긍정적인 영향을 미치는 것으로 나타났음. 3. 만족도는 반응성과 구매행위 사이에 매개효과가 있고 경제와 구매행위 사이에도 매개효과가 있는 것으로 나타났음. Rural terminal logistics are important determinants of the rural residents' online shopping. The service quality of rural online shopping needs good terminal logistics distribution and support chain. As e-commerce expands to rural areas, residents are gradually increasing their expectations on service quality. Taking satisfaction as an intermediary variable, this study explored influences of various dimensions of rural terminal logistics service quality on rural residents' online purchasing behavior, and provided corresponding improvements and development countermeasures for the development of rural terminal logistics service that would improve the quality of life of rural residents. The structural equation models (SEM) and Zhong Lin Wen’s method of mediating effect test were in the analysis (Wen et al., 2004). Distribution reliability and service convenience had positive effects on satisfaction, while economy had a negative effect on satisfaction. Meanwhile, satisfaction had a positive effect on online purchasing behavior, while satisfaction had a mediator effect between responsiveness and purchase behavior, and a mediator effect was also observed between Economy and purchase behavior.

The Effect of Light-Beam Wobble on the Noise Characteristics for an Optical Disk

Cong-Hui Xu,Yu-Xiang Zheng,Liang-Yao Chen,Rong-Jun Zhang 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.5I

The laser beam is usually perpendicular to the optical disk during operation; however, for various reasons, the laser beam may diverge from the normal state with respect to the optical disk, which will cause an unsteadiness in the reflection of the light, and may lead to system noise. In this paper, we simulate the process of such an influence by adding a random variable to the incidence angle of the laser beam by combining an optical-matrix method with the Monte Carlo method. After careful analysis, we put forward some new structures to obtain a high signal-to-noise ratio (SNR) for a certain wavelength of the laser.

Schisantherin A Improves Learning and Memory of Mice with D-Galactose-Induced Learning and Memory Impairment Through Its Antioxidation and Regulation of p19/p53/p21/ Cyclin D1/CDK4/RB Gene Expressions

Cong Liu,Weijing Sun,Ning Li,Jiaqi Gao,Chunyan Yu,Chunmei Wang,Jinghui Sun,Shu Jing,JianGuang Chen,He Li 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7

Schisantherin A (SCA) was evaluated for possible function in restoring the learning and memory impairment induced by D-galactose in mice. ICR mice were treated with D-galactose subcutaneously (220 mg·kg−1), and followed by SCA in different doses (1.25, 2.50 and 5.00 mg·kg−1, administered orally) for 42 days. Effects of SCA on learning and memory were examined by step-through tests and Morris water maze tests. The activity of superoxide dismutase (SOD), the content of malondialdehyde (MDA) in the peripheral blood and hippocampus of mice were assayed by water-soluble tetrazolium-1 (WST-1) and thiobarbituric acid (TBA) methods. The contents of 8 hydroxy deoxy guanosine (8-OHdG) in the hippocampus of mice were detected by immunosorbent assay methods, respectively. Quantitative real-time PCR and Western Blot were respectively used to detect the expression of p19, p53, p21, cyclin D1, CDK4 and RB genes, and the phosphorylation of RB in the hippocampus of mice. We found that SCA significantly improved the learning and memory impairment induced by D-galactose in mice. After SCA treatment, SOD activity was increased and the content of MDA was decreased in both peripheral blood and hippocampus of mice. 8-OHDG content was also decreased in the hippocampus of mice. Furthermore, the expression of p19, p53 and p21 genes was reduced and the expression of cyclin D1 and CDK4 and the phosphorylation of RB protein were elevated in the hippocampus. SCA may improve the learning and memory impairment induced by D-galactose by enhancing the antioxidant capacity, and regulating the expression of p19/p53/p21/cyclinD1/CDK4 genes, and the phosphorylation of RB protein in the hippocampus of mice.

Comprehensive evaluation method for user interface design in nuclear power plant based on mental workload

Yu Chen,Shengyuan Yan,Cong Chi Tran 한국원자력학회 2019 Nuclear Engineering and Technology Vol.51 No.2

Mental workload (MWL) is a major consideration for the user interface design in nuclear power plants(NPPs). However, each MWL evaluation method has its advantages and limitations, thus the evaluationand control methods based on multi-index methods are needed. In this study, fuzzy comprehensiveevaluation (FCE) theory was adopted for assessment of interface designs in NPP based on operators'MWL. An evaluation index system and membership functions were established, and the weights weregiven using the combination of the variation coefficient and the entropy method. The results showed thatmulti-index methods such as performance measures (speed of task and error rate), subjective rating(NASA-TLX) and physiological measure (eye response) can be successfully integrated in FCE for userinterface design assessment. The FCE method has a correlation coefficient compared with most of theoriginal evaluation indices. Thus, this method might be applied for developing the tool to quickly andaccurately assess the different display interfaces when considering the aspect of the operators' MWL.

Involvement of Lysosome Membrane Permeabilization and Reactive Oxygen Species Production in the Necrosis Induced by Chlamydia muridarum Infection in L929 Cells

( Lixiang Chen ),( Cong Wang ),( Shun Li ),( Xin Yu ),( Xue Liu ),( Rongrong Ren ),( Wenwen Liu ),( Xiaojing Zhou ),( Xiaonan Zhang ),( Xiaohui Zhou ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.4

Chlamydiae, obligate intracellular bacteria, are associated with a variety of human diseases. The chlamydial life cycle undergoes a biphasic development: replicative reticulate bodies (RBs) phase and infectious elementary bodies (EBs) phase. At the end of the chlamydial intracellular life cycle, EBs have to be released to the surrounded cells. Therefore, the interactions between Chlamydiae and cell death pathways could greatly influence the outcomes of Chlamydia infection. However, the underlying molecular mechanisms remain elusive. Here, we investigated host cell death after Chlamydia infection in vitro, in L929 cells, and showed that Chlamydia infection induces cell necrosis, as detected by the propidium iodide (PI)-Annexin V double-staining flow-cytometric assay and Lactate dehydrogenase (LDH) release assay. The production of reactive oxygen species (ROS), an important factor in induction of necrosis, was increased after Chlamydia infection, and inhibition of ROS with specific pharmacological inhibitors, diphenylene iodonium (DPI) or butylated hydroxyanisole (BHA), led to significant suppression of necrosis. Interestingly, live-cell imaging revealed that Chlamydia infection induced lysosome membrane permeabilization (LMP). When an inhibitor upstream of LMP, CA-074-Me, was added to cells, the production of ROS was reduced with concomitant inhibition of necrosis. Taken together, our results indicate that Chlamydia infection elicits the production of ROS, which is dependent on LMP at least partially, followed by induction of host-cell necrosis. To our best knowledge, this is the first live-cell-imaging observation of LMP post Chlamydia infection and report on the link of LMP to ROS to necrosis during Chlamydia infection.

Ultrasonic Osteotome Assisted Posterior Endoscopic Cervical Foraminotomy in the Treatment of Cervical Spondylotic Radiculopathy Due to Osseous Foraminal Stenosis

Ye Jiang,Chen Li,Lutao Yuan,Cong Luo,Yuhang Mao,Yong Yu 대한신경외과학회 2023 Journal of Korean neurosurgical society Vol.66 No.4

Objective : To investigate the efficacy and safety of the posterior endoscopic cervical foraminotomy (PECF) using ultrasonic osteotome for the treatment of cervical osseous foraminal stenosis,focusing on introduction of the advantages of ultrasonic osteotome in partial pediculectomy and ventral osteophyte resection in PECF. Methods : Nineteen patients with cervical osseous foraminal stenosis who underwent PECF using ultrasonic osteotome in our institution between April 2018 and April 2021 were enrolled in this study. All the patients were followed up more than 12 months. The patients’ medical data, as well as pre- and postoperative radiologic findings were thoroughly investigated. The visual analogue score (VAS), Japanese Orthopaedic Association (JOA) score, cervical dysfunction index (Neck disability index, NDI), and modified MacNab criteria were used to assess the surgical efficacy. Results : All the patients were successfully treated with PECF using ultrasonic osteotome. The pre- and postoperative VAS, NDI, and JOA scores were significantly improved (p<0.05). According to the modified MacNab criteria, 17 patients were assessed as “excellent”, two patients were assessed as “good” at the last follow-up. There was no dura tear, nerve root damage, incision infection, neck deformity, or other complications. Conclusion : Adequate nerve root decompression can be accomplished successfully with the help of ultrasonic osteotome in PECF, which has the advantage of reducing the probability of damage to the nerve root and dura mater, in addition to the original merits of endoscopic surgery.

Ellipsometric Study of the Optical Properties of Silicon-Based Si:SiO2 Composite Thin Films under Different Annealing Temperatures

Bin Sun,Yu-Xiang Zheng,Cong-Hui Xu,Liang-Yao Chen,Peng Zhou,Yue-Rui Chen,Yu-Fei Kong 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.5I

In our work, silicon and silica composite .lms were prepared by using a magnetron sputtering method, and the samples were annealed in the temperature range between 200 ±C and 600 ±C. After annealing, the samples were investigated by spectroscopic ellipsometry (SE), and the SE spectra were measured in the range of 1.5 eV ≫ 4.5 eV with a dual-rotating-element ellipsometer. In order to investigate the microstructure information of the .lm by .tting the SE spectra using the eective- medium approximation (EMA), we modeled the whole .lm by using a multilayer optical model including a surface oxide layer, a composite layer, and substrate layer. We used dierent mixtures to describe the composite layer, and .nally we found that a mixture of amorphous silicon (a-Si), polycrystalline silicon (p-Si), and silicon dioxide had the best .t to the SE spectra. Whereafter, we studied the dependences of the surface roughness, the layer structure, and the composition on the dierent annealing temperatures and found that with increasing annealing temperature, the surface oxide layer grew in thickness, the silicon dioxide maintained its volume fraction, and a-Si transferred to p-Si.

Glycerol steam reforming over Ni/γ-Al2O3 catalysts modified by metal oxides

Cheng-Hua Xu,Zun-Yu Huang,Chuan-Qi Liu,Hui-Wen Xiao,Jun Chen,Yong-Xiang Zhang,Ya-Cong Lei 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.3

The metal oxides modified Ni/γ-Al2O3 catalysts for glycerol steam reforming were prepared by impregnation. Characterization results of fresh catalysts indicated that the molybdates modification abated the acidity and the stronger metal-support interaction of Ni/γ-Al2O3 catalysts, leading to a stable catalytic activity. Especially, NiMoLa-CaMg/γ-Al2O3 (NiMoLa/CMA) catalyst exhibited no deactivation along with glycerol complete conversion to stable gaseous products containing 69% H2, 20% CO and 10% CO2 during time-on-stream of 42 h. TPO of spent Ni/γ-Al2O3catalysts modified by different components showed that the carbon deposit on acidic sites and NiAl2O4 species led to catalysts deactivation. A lower reforming temperature and a higher LHSV and glycerol content were helpful to the production of syngas from GSR over NiMoLa/CMA; the reverse conditions would improve the formation of H2.