PH 4.3에서 재광화 용액의 포화도에 따른 인공 탈회된 법랑질의 동력학적 변화

이지숙,노병덕,신수정,이윤,공형규,이찬영 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.1

법랑질의 재광화에 영향을 주는 요인으로는 PH, 불소 농도, 포화도 등이 있다. 본 연구에서는 유산 완충 탈회용액을 이용하여 법랑질 시편을 인공 탈회시킨 후, pH 4.3에서 포화도를 0.22, 0.30, 0.35로 달리한 세가지 재광화 용액에 10일간 처리하여 나타나는 변화를 편광현미경으로 관찰하여 전체 탈회 깊이와 건전 표층 폭의 변화를 조사하였다. 또한 Image program (Scion Image analyzer)을 이용하여 병소 부위의 평균 mineral density를 측정하여 탈회와 재광화 후 무기질 변화량을 통해 인공 탈회된 법랑질의 동력학적 변화를 관찰하였다. 1 재광화 후 모든 군에서 건선 표층의 폭이 증가하였는데, 포화도가 증가할수록 건전 표층 폭이 증가하였다 (P< .05) 2 재광화 후 mineral density 변화를 관찰한 결과 포화도가 낮은 군에서는 이온의 침착이 병소 전반적으로 일어났으나, 포화도가 높은 군에서는 건전 표층 부위와 표층하 병소의 하층부에서 이온의 침착으로 mineral density 가 증가하였고 표층하 병소의 상층부에서는 탈회가 진행되어 mineral density가 감소하였다. 3 재광화 후 모든 군에서 무기질량이 증가하였고 전체 탈회 깊이도 증가하였으나 각 군간에 통계적 유의차는 없었다. 본 실험에서 인공 탈회된 시편을 pH 4.3인 재광화 용액에 처리시 포화도가 높을수록 건전 표층에서 더 많은 재광화 현상이 일어났고 표층하 병소에서는 재광화 현상이 적게 일어났으며 재광화 후 모든 군에서 전체 탈회 깊이는 증가하였다. The purpose of this study is to observe and compare the dynamic change of artificially demineralized enamel by remineralization solutions of different degrees of saturation at pH 4.3 In this study, 30 enamel specimens were demineralized artificially by lactic acid buffered solution. Each of 10 specimens was immersed in pH 4.3 remineralization solution of three different degrees of saturation (0.22, 0.30, 0.35) for 10 days. After demineralization and remineralization, images were taken by a polarizing microscope (× 100). The density of lesion were determined from images taken after demineralization and remineralization. During remineralization process, mineral deposition and mineral loss occurred at the same time. After remineralization total mineral amount and width of surfacc lesion increased in all groups. The higher degree of saturation was, the more mineral deposition occurred in surface lesion and the amount of mineral deposition was not much in subsurfacc lesion. Total demineralized depth increased in all groups.

히스토아크릴을 이용한 십이지장 궤양 출혈의 지혈 후 발생한 급성췌장염

유재훈,문원,노지훈,구동영,조영화,김기수,윤준모 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

Upper gastrointestinal bleeding is common and potentially life threatening medical emergency. Emergency endoscopy is the first choice of diagnostic and treatment measure for patients with active upper gastrointestinal bleeding. Histoacryl should be considered a second-line treatment modality when conventional treatments were failed. However, it might cause several complications. Herein, we report a case of acute pancreatitis developed after histoacryl injection therapy for active duodenal ulcer bleeding. A 71-year-old man was admitted with melena and hematemesis. On emergency endoscopy, a 2 cm sized active ulcer with bleeding from an exposedvessel was seen at the duodenal bulb. Attempts to arrest the bleeding with hemoclipping and submucosal epinephrine injection were tried, but failed. We changed the method to endoscopic histoacryl injection, and obtained hemostasis immediately. A few hourslater, after successful hemostasis, patient complained diffuse abdominal pain. Ultrasonography revealed hyperechoic heterogenous diffuse pancreatic enlargement and right pararenal space fluid collection, this ultrasonographic findings and elevated serum pancreatic enzymes are compatible with acute pancreatitis.

Influence of Disease Activity, Coping, and Post-traumatic Growth on Health-Related Quality of Life in Patients with Crohns Disease

Yoon Ji Roh,Hye-Ah Yeom 한국간호과학회 2023 한국간호과학회 학술대회 Vol.2023 No.11

Multiple Step Interlaced Beam Scan to Minimize the Deviation of Radar Detection Performance

Ji Hwan Yoon,Yeonhee Park,Ji Eun Roh,Sung Chul Park 한국전자파학회JEES 2020 Journal of Electromagnetic Engineering and Science Vol.20 No.2

For detection of targets, a radar conventionally scans a specified search volume with a fixed beam lattice of a specified beam spacing. With the fixed beam lattice, the detection performance of the radar within a unit beam lattice changes depending on the line-of-sight angle to a target. In this paper, multiple step interlaced scan is proposed to minimize the deviation of the detection performance due to the change of the target line-of-sight angle. As a figure of merit for the detection performance, the cumulative probability of detection is analyzed for various values of the interlaced scan step with different beam overlap ratios, and the optimal values of the steps to minimize the deviation of the cumulative probability of detection are derived.

전개형 복합재 반사판 안테나의 유연 다물체 동역학 해석

임윤지(Yoon-Ji Lim),오영은(Young-Eun Oh),노진호(Jin-Ho Roh),이수용(Soo-Yong Lee),정화영(Hwa-Young Jung),이재은(Jae-Eun Lee),강덕수(Deok-Soo Kang),윤지현(Ji-Hyeon Yun) 한국항공우주학회 2019 韓國航空宇宙學會誌 Vol.47 No.10

전개형 반사판 안테나의 전개거동 특성을 해석적 그리고 실험적 방법으로 분석하고자 한다. Kane 방정식을 이용하여 전개형 안테나의 다물체 운동방정식을 공식화하였다. 복합재료 반사판의 구조변형 특성을 살펴보기 위해 FSDT(First-order Shear Deformation Theory)를 이용하여 빔 모델로 유한요소 정식화 하였다. 역진자 모델을 이용하여 안테나 전개시간에 따른 스프링 상수 그리고 댐핑 계수들을 결정하였다. 다물체 동력학 해석을 통하여 설계변수에 따른 안테나 반사판의 동적구조 특성을 확인하였고, 무중력 모사 전개실험을 통하여 해석결과 검증 및 거동특성을 실험적으로 관찰하였다. Dynamic behaviors of the deployable composite reflector antenna are numerically and experimentally investigated. Equations of the motion are formalized using Kane’s equation by considering multibody systems with two degrees of freedom such as folding and twisting angles. To interpret structural deformations of the reflector antenna, the composite reflector is modeled using a beam model with the FSDT(First-order Shear Deformation Theory). To determine design parameters such as a torsional spring stiffness and a damping coefficient depending on deployment duration, an inverted pendulum model is simply applied. Based on the determined parameters, dynamic characteristics of the deployable reflector are investigated. In addition, its results are verified and compared through deployment tests using a gravity compensation device.

AESA 레이다의 동시운용모드를 위한 빔 스케줄링 기법

노지은(Ji-Eun Roh),원진주(Jin-Ju Won),윤지환(Ji-Hwan Yoon) 한국전자파학회 2021 한국전자파학회논문지 Vol.32 No.4

최신의 항공기 탑재 능동위상배열레이다(AESA radar, active electronically scanned array radar)에서는 공대공과 공대지 또는 공대공과 공대해 모드를 시분할하여 운용하는 동시운용모드를 제공한다. 본 논문에서는 동시운용모드 적용을 위해 모드별 할당된 부하를 효과적으로 제어할 수 있는 빔 스케줄링 기법에 관한 것으로, 제안된 알고리즘은 AESA 레이다의 모드별 추적 특징을 고려하되, 부하비율, 스캔 비율, 스캔 회수, 스캔 시간 옵션에 따라 모드별 할당된 자원량을 지속적으로 만족하는 동시에, 프레임, bar, 또는 빔 단위로 모드별 탐색 전환 옵션을 제공한다. 또한 부하를 계산하기 위한 모드별 처리율 계산 및 탐색 모드 변경 여부 결정 로직 등을 구성하여 간단한 계산을 통해 부하를 제어할 수 있도록 설계하였다. The modern active electronically scanned array (AESA) airborne radar features an interleaved mode, whereby situational awareness can be maximized via incorporation of the radar’s electronic beam pointing capability. This interleaved mode can enable simultaneous operation of two or more modes, such as the air-to-air and sea surface-search modes, via the technique of time-sharing. One of the key requirements for successful realization of the interleaved mode is a beam scheduler design that facilitates effective control of the allocated resources for each mode. Thus, in this paper, we propose an effective beam scheduler that can control the allocated resources for each mode through the mode-switching option based on the radar’s frames, bars, and beams. Furthermore, the proposed beam scheduler involves the mode-switching decision logic and calculates the processing ratio for each mode.

Age estimation by pulp/tooth area ratio in a Korean sample on digital panoramic radiographs

( Byung-yoon Roh ),( Chang-gyum Kim ),( Sang-seob Lee ),( Won-joon Lee ),( Yo-seob Seo ),( Ji-won Ryu ),( Jong-mo Ahn ),( Chang-lyuk Yoon ) 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 2020 Oral Biology Research (Oral Biol Res) Vol.44 No.4

Age estimation based on the change in the size of the pulp due to secondary dentin deposition can be conducted non-invasively using radiographic photographs. Among these methods, age estimation using the pulp/tooth area ratio is highly accurate. The present study was conducted to apply this method using the panoramic radiographs of a Korean sample population and to evaluate its applicability in the Korean population. The study was conducted using panoramic radiographic images of 349 Koreans aged 20-79 years. The pulp/ tooth area ratio was calculated by measuring the area of the pulp and tooth. Teeth with a single canal, such as maxillary central incisor, lateral incisor, canine, and mandibular canine, were selected. Correlations between this ratio and age were calculated and regression formulas were derived. Age and pulp/tooth area ratio showed relatively low correlations compared with other studies. In particular, men showed lower correlations than women, and upper teeth showed a higher correlation than lower teeth. The regression formulas derived in this study also showed higher errors than those reported in other studies. Age estimation using pulp/tooth area ratio in a Korean using digital panoramic radiographs showed larger errors when compared with previous studies. Morphological diversity of tooth and pulp, indistinct anatomical details in panoramic radiograph, reduction in crown size due to attrition, and ethnic differences are believed to have affected the results.

북극 스발바르 군도 중앙로벤 빙하 해안 지역의 토양 시료 내 메타지놈 기반 미생물 군집 분석

석윤지 ( Yoon Ji Seok ),송은지 ( Eun Ji Song ),차인태 ( In Tae Cha ),이현진 ( Hyunjin Lee ),노성운 ( Seong Woon Roh ),정지영 ( Ji Young Jung ),이유경 ( Yoo Kyung Lee ),남영도 ( Young Do Nam ),서명지 ( Myung Ji Seo ) 한국미생물생명공학회(구 한국산업미생물학회) 2016 한국미생물·생명공학회지 Vol.44 No.2

최근 빙하의 융해로 인해 빙하 해안 지역에 다양한 토양 미생물과 초목들이 드러나고 있다. 본 연구에서는 북극 스발바르 군도 중앙로벤 빙하 해안 지역으로부터 Ion Torrent Personal Genome Machine(PGM)을 활용한 메타지놈 분석을 통해 세균(bacteria), 고균(archaea), 및 진핵생물(eukaryotes)를 포함하는 다양한 미생물 군집을 분석하였다. 연구에 사용된 토양시료는 빙하 후퇴에 따른 토양의 노출 시기에 따라 2개 지역(ML4 및 ML7)으로부터 수집하였다. ML4 및 ML7 시료의 메타지놈 염기서열을 기반으로 총 2,798,108 및 1,691,859 reads가 각각 미생물 군집 분석에 활용되었다. Domain (계) 수준에서 미생물 군집의 상대 빈도를 분석한 결과 2개 시료 모두 세균(86-87%)이 높은 반면 고균과 진핵생물은 1% 미만으로 존재하는 것으로 나타났다. 또한 약 12%의 염기서열은 기존에 분류되지 않은(unclassified) 서열로 분석되었다. 세균의 경우 Proteobacteria(40.3% for ML4 and 43.3%for ML7)와 Actinobacteria(22.9% and 24.9%)가 우점하는 것으로 분석되었다. 고균의 경우에는 Euryarchaeota(84.4% and 81.1%)및 Crenarchaeota(10.6% and 13.1%), 그리고 진핵생물의 경우에는 Ascomycota(33.8% and 45.0%)가 우점하는 것으로 분석되었다. 본 연구를 통해 Ion Torrent PGM 플랫폼을 활용한 메타지놈 분석이 북극의 중앙로벤 빙하 해안 지역의 전체 미생물 군집 구조를 파악하는데 충분히 적용될 수 있을 것으로 사료된다. Recent succession of soil microorganisms and vegetation has occurred in the glacier foreland, because of glacier thawing. In this study, whole microbial communities, including bacteria, archaea, and eukaryotes, from the glacier foreland of Midtre Lovenbreen in Svalbard were analyzed by metagenome sequencing, using the Ion Torrent Personal Genome Machine (PGM) platform. Soil samples were collected from two research sites (ML4 and ML7), with different exposure times, from the ice. A total of 2,798,108 and 1,691,859 reads were utilized for microbial community analysis based on the metagenomic sequences of ML4 and ML7, respectively. The relative abundance of microbial communities at the domain level showed a high proportion of bacteria (about 86-87%), whereas archaeal and eukaryotic communities were poorly represented by less than 1%. The remaining 12% of the sequences were found to be unclassified. Predominant bacterial groups included Proteobacteria (40.3% from ML4 and 43.3% from ML7) and Actinobacteria (22.9% and 24.9%). Major groups of Archaea included Euryarchaeota (84.4% and 81.1%), followed by Crenarchaeota (10.6% and 13.1%). In the case of eukaryotes, both ML4 and ML7 samples showed Ascomycota (33.8% and 45.0%) as the major group. These findings suggest that metagenome analysis using the Ion Torrent PGM platform could be suitably applied to analyze whole microbial community structures, providing a basis for assessing the relative importance of predominant groups of bacterial, archaeal, and eukaryotic microbial communities in the Arctic glacier foreland of Midtre Lovenbreen, with high resolution.

The metabolic mechanism of C-14 labeled chitosan in mice

Kim, Kwang Yoon,Kim, Young Ho,Kim, Hee Kyung,Bom, Hee Seung,Kim, Ji Yeul,Yoshikazu Nishimura,Jkim, ung Woo,Oh, Chang Suck,Park, Ro Dong,Lee, Hyun Chul,Kang, Moon Il,Roh, Young Bok 한국키틴키토산학회 1998 한국키틴키토산학회지 Vol.3 No.1

Chitin is exists in the exoskeleton of crustaceans and chitosan can be obtained by deacetylation of chitin. As chitosan has a chelating characteristics, it was used radiostrontium chelator in the rats and mice. It also can be used as a healthy food and medicine. The purpose of the prsent study is to investigate the chitosan distribution and excretory route of 14C-chitosan in the animal body. 14C-chitosan was prepared and intravenously administered to the vein of mice and also intraorally ingested. The body distribution of chitosan was studied by autoradiography and the urinary excretion was counted. C-14 label chitosan was showed high distribution in the liver. And 10~20% of chitosan was excreted to the urine through kidney within few days. Chitosan was gathered into gromerulus in kidney and excreted from three hours. It was concluded that chitosan has no target organs and liver distribution is a sort of only passing route for the urinary excretion by way of kidney.

Prevalence of the <i>CTNNB1</i> mutation genotype in surgically resected fibromatosis of the breast

Kim, Taeeun,Jung, Eun Ah,Song, Ji Young,Roh, Ji Hyeon,Choi, Jong Sun,Kwon, Jee Eun,Kang, So Young,Cho, Eun Yoon,Shin, Jung Hee,Nam, Suk‐,Jin,Yang, Jung Hyun,Choi, Yoon‐,La Blackwell Publishing Ltd 2012 Histopathology Vol.60 No.2

<P>Kim T, Jung E A, Song J Y, Roh J H, Choi J S, Kwon J E, Kang S Y, Cho E Y, Shin J H, Nam S‐J, Yang J H & Choi Y‐L 
(2012) <I>Histopathology</I>?<B>60,</B> 347–356 
<B>Prevalence of the <I>CTNNB1</I> mutation genotype in surgically resected fibromatosis of the breast</B></P><P><B>Aims: </B> To investigate <I>CTNNB1</I> mutation and β‐catenin expression in resected breast fibromatosis and to identify potential molecular markers of fibromatosis of the breast.</P><P><B>Methods and results: </B> We selected 12 patients with fibromatosis of the breast who underwent surgical resection and were confirmed by histological examination. Ultrasonography findings for 10 patients were reviewed and only two cases were suspicious for fibromatosis on imaging. On core needle biopsy for pre‐operative diagnoses, only three cases were histologically suspicious for fibromatosis. Mutations in exon 3 of <I>CTNNB1</I> were detected by direct DNA sequencing in nine (75.0%) cases: all were c.121G>A (p.T41A), which was much more frequent in breast fibromatoses than in other soft tissue lesions. Nuclear β‐catenin expression was observed in all cases and the level of expression was higher in cases with mutation. In eight of nine cases, the matched biopsy specimen showed the same <I>CTNNB1</I> mutation status as the pre‐operative specimen.</P><P><B>Conclusions: </B> In the majority of cases, clinical presentation and breast imaging are highly suspicious for carcinoma. Definitive pre‐operative pathological diagnosis by core needle biopsy is difficult. <I>CTNNB1</I> mutation and nuclear β‐catenin expression are frequently detected in sporadic breast fibromatoses, suggesting their potential as a useful tool to distinguish breast fibromatoses from other neoplasms.</P>