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- 검색키워드
- 저자 : Ying-Chieh Fang (검색결과 8 건)
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A Looping Population Learning Algorithm for the Makespan/Resource Trade-offs Project Scheduling
Ying-Chieh Fang,Chiuh-Cheng Chyu 대한산업공학회 2009 Industrial Engineeering & Management Systems Vol.8 No.3
Population learning algorithm (PLA) is a population-based method that was inspired by the similarities to the phenomenon of social education process in which a diminishing number of individuals enter an increasing number of learning stages. The study aims to develop a framework that repeatedly applying the PLA to solve the discrete resource constrained project scheduling problem with two objectives: minimizing project makespan and renewable resource availability, which are two most common concerns of management when a project is being executed. The PLA looping framework will provide a number of near Pareto optimal schedules for the management to make a choice. Different improvement schemes and learning procedures are applied at different stages of the process. The process gradually becomes more and more sophisticated and time consuming as there are less and less individuals to be taught. An experiment with ProGen generated instances was conducted, and the results demonstrated that the looping framework using PLA outperforms those using genetic local search, particle swarm optimization with local search, scatter search, as well as biased sampling multi-pass algorithm, in terms of several performance measures of proximity. However, the diversity using spread metric does not reveal any significant difference between these five looping algorithms.
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Fang-Ying Chiu,Duen-Pang Kuo,Yung-Chieh Chen,Yu-Chieh Kao,Hsiao-Wen Chung,Cheng-Yu Chen 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.6
Objective: The aim of this study was to investigate diffusion tensor (DT) imaging-derived properties of benign oligemia, true “at risk” penumbra (TP), and the infarct core (IC) during the first 3 hours of stroke onset. Materials and Methods: The study was approved by the local animal care and use committee. DT imaging data were obtained from 14 rats after permanent middle cerebral artery occlusion (pMCAO) using a 7T magnetic resonance scanner (Bruker) in room air. Relative cerebral blood flow and apparent diffusion coefficient (ADC) maps were generated to define oligemia, TP, IC, and normal tissue (NT) every 30 minutes up to 3 hours. Relative fractional anisotropy (rFA), pure anisotropy (rq), diffusion magnitude (rL), ADC (rADC), axial diffusivity (rAD), and radial diffusivity (rRD) values were derived by comparison with the contralateral normal brain. Results: The mean volume of oligemia was 24.7 ± 14.1 mm3, that of TP was 81.3 ± 62.6 mm3, and that of IC was 123.0 ± 85.2 mm3 at 30 minutes after pMCAO. rFA showed an initial paradoxical 10% increase in IC and TP, and declined afterward. The rq, rL, rADC, rAD, and rRD showed an initial discrepant decrease in IC (from -24% to -36%) as compared with TP (from -7% to -13%). Significant differences (p < 0.05) in metrics, except rFA, were found between tissue subtypes in the first 2.5 hours. The rq demonstrated the best overall performance in discriminating TP from IC (accuracy = 92.6%, area under curve = 0.93) and the optimal cutoff value was -33.90%. The metric values for oligemia and NT remained similar at all time points. Conclusion: Benign oligemia is small and remains microstructurally normal under pMCAO. TP and IC show a distinct evolution of DT-derived properties within the first 3 hours of stroke onset, and are thus potentially useful in predicting the fate of ischemic brain.
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A Looping Population Learning Algorithm for the Makespan/Resource Trade-offs Project Scheduling
Fang, Ying-Chieh,Chyu, Chiuh-Cheng Korean Institute of Industrial Engineers 2009 Industrial Engineeering & Management Systems Vol.8 No.3
Population learning algorithm (PLA) is a population-based method that was inspired by the similarities to the phenomenon of social education process in which a diminishing number of individuals enter an increasing number of learning stages. The study aims to develop a framework that repeatedly applying the PLA to solve the discrete resource constrained project scheduling problem with two objectives: minimizing project makespan and renewable resource availability, which are two most common concerns of management when a project is being executed. The PLA looping framework will provide a number of near Pareto optimal schedules for the management to make a choice. Different improvement schemes and learning procedures are applied at different stages of the process. The process gradually becomes more and more sophisticated and time consuming as there are less and less individuals to be taught. An experiment with ProGen generated instances was conducted, and the results demonstrated that the looping framework using PLA outperforms those using genetic local search, particle swarm optimization with local search, scatter search, as well as biased sampling multi-pass algorithm, in terms of several performance measures of proximity. However, the diversity using spread metric does not reveal any significant difference between these five looping algorithms.
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Ying-Cheng Chiang,Chi-An Chen,Chun-Ju Chiang,Tsui-Hsia Hsu,Ming-Chieh Lin,San-Lin You,Wen-Fang Cheng,Mei-Shu Lai 대한부인종양학회 2013 Journal of Gynecologic Oncology Vol.24 No.4
Objective: To investigate the changes of incidence and prognosis of epithelial ovarian cancer in thirty years in Taiwan. Methods: The databases of women with epithelial ovarian cancer during the period from 1979 to 2008 were retrieved from the National Cancer Registration System of Taiwan. The incidence and prognosis of these patients were analyzed. Results: Totally 9,491 patients were included in the study. The age-adjusted incidences of epithelial ovarian cancer were 1.01, 1.37, 2.37, 3.24, 4.18, and 6.33 per 100,000 person-years, respectively, in every 5-year period from 1979 to 2008. The age-specific incidence rates increased especially in serous, endometrioid and clear cell carcinoma, and the age of diagnosis decreased from sixty to fifty years old in the three decades. Patients with mucinous, endometrioid, or clear cell carcinoma had better long-term survival than patients with serous carcinoma (log rank test, p<0.001). Patients with undifferentiated carcinoma or carcinosarcoma had poorer survival than those with serous carcinoma (log rank test, p<0.001). The mortality risk of age at diagnosis of 30-39 was significantly higher than that of age of 70 years or more (test for trend, p<0.001). The mortality risk decreased from the period of 1996-1999 (hazard ratio [HR], 0.90; p=0.054) to the period after 2000 (HR, 0.74; p<0.001) as compared with that from the period of 1991-1995. Conclusion: An increasing incidence and decreasing age of diagnosis in epithelial ovarian cancer patients were noted. Histological type, age of diagnosis, and treatment period were important prognostic factors for epithelial ovarian carcinoma.
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Sun, Ying,Chien, Shang-Chieh,Yip, Hin-Lap,Chen, Kung-Shih,Zhang, Yong,Davies, Joshua A.,Chen, Fang-Chung,Lin, Baoping,Jen, Alex K.-Y. The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.12
<P>A detailed model study has shown that thin film morphology and bulk-heterojunction solar cell performance can be significantly improved by systematic tuning of the surface energy of the conjugated donor polymer through side-chain functionalization. Thiophene-flanked diketopyrrolopyrrole (DPP) moieties with different contents of cyanohexane side chains were incorporated into three low band-gap conjugated copolymers (<B>PIDTDPP1</B>, <B>PIDTDPP2</B> and <B>PIDTDPP3</B>) consisting of indacenodithiophene (IDT) donors and DPP acceptors. The resulting polymers possessed good solubility in common organic solvents and showed similar energy levels, bandgaps, and hole mobilities. However, the introduction of cyano groups onto the terminal of side-chains significantly changed their surface energy. Topographical images obtained from atomic force microscopy (AFM) proved that a better matched surface energy between polymer and PC<SUB>71</SUB>BM had led to enhanced miscibility, which resulted in better BHJ film morphology. Consistent with the surface energy enhancement, the performance of BHJ photovoltaic devices increased from 0.97% for <B>PIDTDPP1</B>, to 2.16% for <B>PIDTDPP2</B> then to 3.67% for <B>PIDTDPP3</B>. These results clearly reveal that tuning surface energy is an effective way to improve the morphology of the BHJ active layer and efficiency of the photovoltaic device.</P> <P>Graphic Abstract</P><P>We have shown that significantly improved thin film morphology and bulk-heterojunction solar cell performance can be achieved by systematically tuning the surface energy of conjugated polymer donors through side-chain functionalization. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2jm15517f'> </P>
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Sun, Ying,Chien, Shang-Chieh,Yip, Hin-Lap,Zhang, Yong,Chen, Kung-Shih,Zeigler, David F.,Chen, Fang-Chung,Lin, Baoping,Jen, Alex K.-Y. Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.35
<P>Two new semiconducting polymers based on indacenodithiophene and thiadiazolo[3,4-<I>c</I>]pyridine units were synthesized <I>via</I> Stille coupling polymerization. The polymers, PIDTPyT and PIDTDTPyT, exhibited main absorption bands in the range of 550–800 nm while their absorption maxima were located at around 700 nm in films. With two additional thiophene spacers, PIDTDTPyT showed a broader absorption band but a 20 nm blue-shifted maximum peak compared to that of PIDTPyT. Both of the polymers possess low bandgaps (∼1.6 eV) and deep energy levels for both the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO). Organic field-effect transistors (OFETs) device measurements indicate that PIDTPyT and PIDTDTPyT have high hole carrier mobilities of 0.066 and 0.045 cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP>, respectively, with the on/off ratio on the order of 10<SUP>6</SUP>. Bulk heterojunction photovoltaic devices consisting of the copolymers and PC<SUB>71</SUB>BM gave power conversion efficiencies (PCE) as high as 3.91% with broadband photo-response in the range of 300–800 nm. The relationships between the photovoltaic performance and film morphology, energy levels, hole mobilities are discussed.</P> <P>Graphic Abstract</P><P>Low bandgap regiorandom polymers based on indacenodithiophene and thiadiazolo[3,4-<I>c</I>]pyridine units showed excellent OFET hole mobilities and promising photovoltaic device performance as high as 3.91%. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm11564b'> </P>
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Association of AXIN1 With Parkinson’s Disease in a Taiwanese Population
Hwa-Shin Fang,Chih-Ying Chao,Chun-Chieh Wang,Wen-Lang Fan,Po-Jung Huang,Hon-Chung Fung,Yih-Ru Wu 대한파킨슨병및이상운동질환학회 2022 Journal Of Movement Disorders Vol.15 No.1
A meta-analysis of locus-based genome-wide association studies recently identified a relationship between AXIN1 and Parkinson’s disease (PD). Few studies of Asian populations, however, have reported such a genetic association. The influences of rs13337493, rs758033, and rs2361988, three PD-associated genetic variants of AXIN1, were investigated in the present study because AXIN1 is related to Wnt/β-catenin signaling.
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