Fabrication of highly sensitive platforms (surfaces) for the environmental and biological monitoring system

Jongheop Yi,Inhee Choi,Surin Hong 한국생물공학회 2007 한국생물공학회 학술대회 Vol.2007 No.10

APPLICATION OF NANOTECHNOLOGY FOR AN ADVANCED ENVIRONMENTAL TECHNOLOGY

( Jongheop Yi ) 한국공업화학회 2003 한국공업화학회 연구논문 초록집 Vol.2003 No.-

Thermal Method for Prediction of Host Selectivity to Guest Isomers

Kim, Jinsoo,Yi, Jongheop,Kim, Woo-Sik The Society of Chemical Engineers, Japan 2009 Journal of chemical engineering of Japan Vol.42 No.10

<P>Differential scanning calorimetric analysis was employed to determine the thermal property of the inclusion compounds; the purpose of performing the analysis was to elucidate the possibility of its use as a tool for predicting host selectivity to a given isomer mixture. From the analysis, it was observed that the energy of guanidinium 4,4′-biphenyldisulfonate (G<SUB>2</SUB>BPDS·(<I>p</I>-xylene)) is the highest among all inclusion compounds, whereas that of G<SUB>2</SUB>BPDS·(<I>m</I>-xylene) is the lowest among them. The result agrees with the selective preference of the G<SUB>2</SUB>BPDS host in a previous experiment. Similarly, the guest release onset temperature of the G<SUB>2</SUB>BPDS inclusion compounds also decreased in the order G<SUB>2</SUB>BPDS·(<I>p</I>-xylene) > G<SUB>2</SUB>BPDS·(<I>o</I>-xylene) > G<SUB>2</SUB>BPDS·(<I>m</I>-xylene). In the case of guanidinium 2,6-naphthalenedisulfonate (G<SUB>2</SUB>NDS) inclusion compounds, both the energy and the guest release onset temperature of G<SUB>2</SUB>NDS·(<I>p</I>-xylene) were higher than those of G<SUB>2</SUB>NDS·3(<I>o</I>-xylene). In fact, the structure of G<SUB>2</SUB>NDS·(<I>p</I>-xylene) was stabilized to a great extent by the CH···O interaction between the host and guest as compared to the G<SUB>2</SUB>NDS·3(<I>o</I>-xylene) structure. Consequently, from the good agreement between the thermal property of inclusion compounds and host selectivity, it was noted that the differential scanning calorimetric study of inclusion compounds can be performed to predict the host selectivity prior to the competition experiment.</P>

Advances in Environmental Technologies via the Application of Mesoporous Materials

Kim, Younghun,Yi, Jongheop 한국공업화학회 2004 Journal of Industrial and Engineering Chemistry Vol.10 No.1

This review describes (inorganic-organic hybrid) mesoporous silica and alumina preparation with a uniform pore structure, as well as some environmental applications. Functional organic groups can be incorporated in the mesoporous materials by grafting, co-condensation and imprinting methods, and these groups affect the hydrophilicity/hydrophobicity of the surface and its affinity for metal ions. Applications of mesoporous materials are highlighted, including catalysts for hydrogenation and hydrodechlorinaton, and the sorption of heavy metal ions, anions, and organics. Because of their controlled porosity and ultrahigh surface-to-volume ratios, these materials show superior catalytic activity and higher adsorption capacities than amorphous or non-porousmaterials.

환경유해성을 고려한 정량적 환경영향평가방법

차순우,이종협 한국화학공학회 1998 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.36 No.5

전과정평가(Life Cycle Assessment, LCA)는 제품이나 공정의 환경에 대한 잠재적 영향을 평가하는 방법으로 알려져 있다. LCA는 목적 및 범위설정, 목록분석, 영향평가, 해석으로 구성되어 있으며, 전과정 단계를 보통 원료수집단계, 제품제조단계, 수송 및 유통단계, 제품사용단계, 재활용 또는 폐기단계로 분류하여 평가한다. 본 연구에서는 전 과정에 걸쳐 사용되는 모든 물질 및 에너지가 결국에는 폐기물형태로 배출된다는 점을 바탕으로 하여, 제품 및 공정에 대한 정량적 전과정평가방법을 제시하였다. 배출되는 폐기물의 형태를 기상, 액상, 고상 폐기물로 구분하고, 배출되는 각 물질이 환경에 미치는 유해 정도를 평가하기 위한 환경부담지수를 도입하였다. 본 논문에서는 이 방법을 적용하기 위한 방법론이 설명되어 있으며, 전과정이 비슷한 두 제품의 예를 통하여 이 방법을 적용하여, 제품 및 공정에 대하여 환경영향을 분석하였다. 영향평가 결과 각 단계별 환경유해성 정도를 정량화할 수 있었으며, 공정의 개선 가능성에 대한 판단기준을 제시 할 수 있었다. Life Cycle Assessment(LCA) is known as a method investigating the potential effects of products or any processes an the environments. LCA is composed of goal & scope definition, inventory analysis, impact assessment and interpretation. The evaluation stages for the LCA are raw material collection manufacturing products, transport, usage and recycle or disposal. In this study a LCA methodology is proposed based on the concepts that materials and energy used are, converted into various types of wastes and that the wastes generated affect the environment. The wastes released are classified into gaseous, liquid and solid types. The environmental burden factor for each chemical compound in the wastes is introduced to assess the effect of hazardous waste, on the environment during the LCA procedure. Results show that the propose evaluation mothod of environmental impact in LCA provides the quantified criteria for the improvement of products and processes. A case study is presented to address the advantage of the proposed LCA method.

화학산업의 청정기술 개발

김영훈(Younghun Kim),이종협(Jongheop Yi),김화용(Hwayong Kim),이현구(Hyun-Ku Rhe) 한국청정기술학회 2001 청정기술 Vol.7 No.1

Biomarker gene response in male Medaka (<i>Oryzias latipes</i>) chronically exposed to silver nanoparticle

Pham, Chi Hoa,Yi, Jongheop,Gu, Man Bock Elsevier 2012 Ecotoxicology and environmental safety Vol.78 No.-

<P><B>Abstract</B></P><P>The chronic toxicity test has been conducted for twenty-eight days to characterize the hepatic expression levels of eight stress-related genes after exposing Medaka to two doses of silver nitrate or a silver nanoparticle (Ag-NP) using real time RT-PCR analysis. This extends our previously published work to include three additional biomarkers and three later time points. In comparing with the control, the significant induction of MT and GST genes in livers of the fish exposed to 1μg/l Ag-NPs was observed at various time points during the test period. The <I>Orla C3-1</I> (Medaka) gene was slightly induced only with 1μg/l Ag-NPs at 7-day exposure while the suppression of p53 and HSP70 was recorded in all exposures at the end of the test. The gene encoding transferrin was repressed at day 21 by both silver types and at every exposure dosage. These results revealed that the Ag-NPs increase metal detoxification, oxidative and inflammatory stress, and finally stimulate immune responses in Medaka. The conspicuous induction of choriogenin L and vitellogenin 1 in male fish exposed to Ag-NPs, especially at 7- and 21-day, compared with the exposures of AgNO<SUB>3</SUB> or control was the first attempt to examine estrogenic effects of Ag-NPs.</P> <P><B>Highlights</B></P><P>► Male Medaka were exposed to two doses of AgNO<SUB>3</SUB> or Ag-NPs for 28 days. ► Hepatic expression level of eight stress-related genes was characterized. ► Ag-NPs increase metal detoxification, oxidative and inflammatory stresses. ► Our study is the first attempt to examine estrogenic effects of Ag-NPs.</P>

Sensitive and molecular size-selective detection of proteins using a chip-based and heteroliganded gold nanoisland by localized surface plasmon resonance spectroscopy

Hong, Surin,Lee, Suseung,Yi, Jongheop Springer 2011 Nanoscale research letters Vol.6 No.1

<P>A highly sensitive and molecular size-selective method for the detection of proteins using heteroliganded gold nanoislands and localized surface plasmon resonance (LSPR) is described. Two different heteroligands with different chain lengths (3-mercaptopionicacid and decanethiol) were used in fabricating nanoholes for the size-dependent separation of a protein in comparison with its aggregate. Their ratios on gold nanoisland were optimized for the sensitive detection of superoxide dismutase (SOD1). This protein has been implicated in the pathology of amyotrophic lateral sclerosis (ALS). Upon exposure of the optimized gold nanoisland to a solution of SOD1 and aggregates thereof, changes in the LSPR spectra were observed which are attributed to the size-selective and covalent chemical binding of SOD1 to the nanoholes. With a lower detection limit of 1.0 ng/ml, the method can be used to selectively detect SOD1 in the presence of aggregates at the molecular level.</P>

청정공정구현을 위한 나노기술기반 환경 센싱 기술의 개발

김영훈(Younghun Kim),이종협(Jongheop Yi) 한국청정기술학회 2005 청정기술 Vol.11 No.2

Selective Activation of Methane on Single-Atom Catalyst of Rhodium Dispersed on Zirconia for Direct Conversion

Kwon, Yongwoo,Kim, Tae Yong,Kwon, Gihun,Yi, Jongheop,Lee, Hyunjoo American Chemical Society 2017 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.139 No.48

<P>Direct methane conversion into value-added products has become increasingly important. Because of inertness of methane, cleaving the first C–H bond has been very difficult, requiring high reaction temperature on the heterogeneous catalysts. Once the first C–H bond becomes activated, the remaining C–H bonds are successively dissociated on the metal surface, hindering the direct methane conversion into chemicals. Here, a single-atom Rh catalyst dispersed on ZrO<SUB>2</SUB> surface has been synthesized and used for selective activation of methane. The Rh single atomic nature was confirmed by extended X-ray fine structure analysis, electron microscopy images, and diffuse reflectance infrared Fourier transform spectroscopy. A model of the single-atom Rh/ZrO<SUB>2</SUB> catalyst was constructed by density functional theory calculations, and it was shown that CH<SUB>3</SUB> intermediates can be energetically stabilized on the single-atom catalyst. The direct conversion of methane was performed using H<SUB>2</SUB>O<SUB>2</SUB> in the aqueous solution or using O<SUB>2</SUB> in gas phase as oxidants. Whereas Rh nanoparticles produced CO<SUB>2</SUB> only, the single-atom Rh catalyst produced methanol in aqueous phase or ethane in gas phase.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2017/jacsat.2017.139.issue-48/jacs.7b11010/production/images/medium/ja-2017-11010p_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja7b11010'>ACS Electronic Supporting Info</A></P>