Freeze Depth Predicting of Permafrost Subgrade based on Moisture and Thermal Coupling Model

Min Ye,Yanfang Hufangfu,Xuesong Mao 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.6

Water and heat conditions and the interactions between them are the key factors in highway freeze damage. A 2-D moisturethermal coupling model has been developed to analyze the temperature profile of the permafrost subgrade and to more thoroughly understand the moisture and thermal transport in subgrade soil. The model accounts for the effects of heat generation, internal conduction and convection, and moisture transport to accurately predict the freeze depth of the subgrade. This model formulates the control equation of the temperature field, the moisture field and their coupling. A commercially available finite element package (ANSYS) is used to solve the simulation. The numerical calculations are compared with in-situ test results on the Qinghai-Tibet Highway and appear to be in strong agreement. The accuracy and precision of the coupling model are superior to the traditional single-field model, which indicates the model’s suitability for predicting the freeze depth of the permafrost subgrade. This model can aid in prevention of highway damage by predicting periods of subgrade thaw and elevated water content such that traffic restrictions can be effectively implemented.

Tea consumption is associated with a reduced risk of coronary heart disease in female but not male populations in Guangzhou, China

Chen, Ying,Ye, Yanfang,Zhang, Zhen,Zhang, Chi,Chen, Minyu,Pang, Jun,Zhou, Shuxian,Xiang, Qiuling The Korean Nutrition Society 2019 Nutrition Research and Practice Vol.13 No.5

BACKGROUND/OBJECTIVES: The association between tea consumption and risk of coronary heart disease (CHD) remains controversial. This study aimed to determine whether tea consumption has an effect on CHD risk in Chinese adults. SUBJECTS/METHODS: In this hospital-based case-control study, 267 cases of CHD and 235 non-CHD controls were enrolled. Blood samples from all cases were examined. Cardiac function indices (left ventricular ejection fraction, left ventricular end-diastolic dimension, lactate dehydrogenase, and creatine kinase of the muscle or brain type), blood lipid index (high-density lipoprotein cholesterol), and blood coagulation function indices (fibrinogen and activated partial thromboplastin time) were recorded. Tea consumption of study participants was assessed by a specifically designed questionnaire. The baseline characteristics of the study populations were recorded, and CHD-related biomarkers were detected. Differences in baseline characteristics of the study participants were examined using t-tests for continuous variables and chi-squared tests for categorical variables. Unconditional logistic regression was used to measure the association between tea and CHD. RESULTS: There were significant differences in cardiac function indices, blood lipid index, and blood coagulation indices between CHD cases and controls (P < 0.05). We found tea consumption reduced CHD risk in female participants (adjusted odds ratio (OR) = 0.484, 95% CI: 0.242-0.968, P = 0.0403). Regarding the type of tea consumed, the risk of CHD was reduced in women who drank partially fermented tea (adjusted OR = 0.210, 95% CI: 0.084-0.522, P = 0.0008). Analytic results for the amount of tea consumed per unit time showed CHD risk was reduced in women who consumed 1-2 cups of tea per day (adjusted OR = 0.291, 95% CI: 0.131-0.643, P = 0.0023). A tea-drinking frequency of > 6 days/week was beneficial for CHD prevention (adjusted OR = 0.183, 95% CI: 0.049-0.679, P = 0.0112). When analyzed according to the duration of tea consumption, the risk of CHD was reduced in participants who had been drinking tea for 10-20 years (adjusted OR = 0.360, 95% CI: 0.137-0.946, P = 0.0382). CONCLUSIONS: Tea consumption is associated with a reduced risk of CHD in female but not male populations in Guangzhou.

Tea consumption is associated with a reduced risk of coronary heart disease in female but not male populations in Guangzhou, China

Ying Chen,Yanfang Ye,Zhen Zhang,Chi Zhang,Minyu Chen,Jun Pang,Shuxian Zhou,Qiuling Xiang 한국영양학회 2019 Nutrition Research and Practice Vol.13 No.5

BACKGROUND/OBJECTIVES: The association between tea consumption and risk of coronary heart disease (CHD) remains controversial. This study aimed to determine whether tea consumption has an effect on CHD risk in Chinese adults. SUBJECTS/METHODS: In this hospital-based case-control study, 267 cases of CHD and 235 non-CHD controls were enrolled. Blood samples from all cases were examined. Cardiac function indices (left ventricular ejection fraction, left ventricular end-diastolic dimension, lactate dehydrogenase, and creatine kinase of the muscle or brain type), blood lipid index (high-density lipoprotein cholesterol), and blood coagulation function indices (fibrinogen and activated partial thromboplastin time) were recorded. Tea consumption of study participants was assessed by a specifically designed questionnaire. The baseline characteristics of the study populations were recorded, and CHD-related biomarkers were detected. Differences in baseline characteristics of the study participants were examined using t-tests for continuous variables and chi-squared tests for categorical variables. Unconditional logistic regression was used to measure the association between tea and CHD. RESULTS: There were significant differences in cardiac function indices, blood lipid index, and blood coagulation indices between CHD cases and controls (P < 0.05). We found tea consumption reduced CHD risk in female participants (adjusted odds ratio (OR) = 0.484, 95% CI: 0.242-0.968, P = 0.0403). Regarding the type of tea consumed, the risk of CHD was reduced in women who drank partially fermented tea (adjusted OR = 0.210, 95% CI: 0.084-0.522, P = 0.0008). Analytic results for the amount of tea consumed per unit time showed CHD risk was reduced in women who consumed 1-2 cups of tea per day (adjusted OR = 0.291, 95% CI: 0.131-0.643, P = 0.0023). A tea-drinking frequency of > 6 days/week was beneficial for CHD prevention (adjusted OR = 0.183, 95% CI: 0.049-0.679, P = 0.0112). When analyzed according to the duration of tea consumption, the risk of CHD was reduced in participants who had been drinking tea for 10-20 years (adjusted OR = 0.360, 95% CI: 0.137-0.946, P = 0.0382). CONCLUSIONS: Tea consumption is associated with a reduced risk of CHD in female but not male populations in Guangzhou.

Local Similarity based Discriminant Analysis for Face Recognition

( Xinguang Xiang ),( Fan Liu ),( Ye Bi ),( Yanfang Wang ),( Jinhui Tang ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.11

Fisher linear discriminant analysis (LDA) is one of the most popular projection techniques for feature extraction and has been widely applied in face recognition. However, it cannot be used when encountering the single sample per person problem (SSPP) because the intra-class variations cannot be evaluated. In this paper, we propose a novel method called local similarity based linear discriminant analysis (LS_LDA) to solve this problem. Motivated by the “divide-conquer” strategy, we first divide the face into local blocks, and classify each local block, and then integrate all the classification results to make final decision. To make LDA feasible for SSPP problem, we further divide each block into overlapped patches and assume that these patches are from the same class. To improve the robustness of LS_LDA to outliers, we further propose local similarity based median discriminant analysis (LS_MDA), which uses class median vector to estimate the class population mean in LDA modeling. Experimental results on three popular databases show that our methods not only generalize well SSPP problem but also have strong robustness to expression, illumination, occlusion and time variation.

Whole-life health monitoring and fault prediction for spur gears

Shumiao Zuo,Xiangyang Xu,Shuyang Ye,Peng Dong,Jin Xu,Yudong Zhang,Yanfang Liu 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11

Whole-life health monitoring and fault prediction for spur gears

Shumiao Zuo,Xiangyang Xu,Shuyang Ye,Peng Dong,Jin Xu,Yudong Zhang,Yanfang Liu 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11

Feasibility, accuracy and acceptability of self-sampled human papillomavirus testing using careHPV in Cambodia: a cross-sectional study

Zhi-yao You,Jing Li,Miao-fang Wu,Hui Li,Yanfang Ye,Li-juan Wang,Zhongqiu Lin 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.1

Objective: Self-sampled human papillomavirus (HPV) testing is a potential option forcer vical cancer screening, but research is scarce in Cambodia. We evaluated the feasibility,accuracy, and acceptability of self-sampled HPV testing using careHPV. Methods: A cross-sectional study including women aged 20–49 years attending 2 nationalhospitals in the capital city was conducted. Women under went both self-sampling andclinician-sampling of specimens, and were then asked to complete an acceptabilityquestionnaire. The paired samples were analyzed for high-risk HPV by careHPV andgenotyped by polymerase chain reaction (PCR). Results: A total of 375 women were eligible for inclusion. Based on PCR, 78.9% were negativefor HPV in both self and clinician-samples, 9.9% had a complete HPV type match, and 6.1%had all HPV types in clinician-samples also detected in self-samples. In 5.1%, one or more HPVtypes identified in the clinician-samples were missed in self-samples. When using careHPV,the overall agreement between the 2 sampling methods was 95.7% (95% confidence inter val[CI]=95.8–95.6) with good concordance (κ=0.66, 95% CI=0.56–0.76). Nearly 90% of the womenpreferred clinician-sampling over self-sampling, citing greater comfort, ease, and speed. Conclusion: Self-sampled HPV testing using careHPV could be an option for cer vical cancerscreening in Cambodia; however, it requires periodic quality control of handling procedures. In addition, women’s health education regarding the accuracy of self-sampled HPV testingand the importance of follow-up in cases of positive results is needed.

A phase I dose-finding trial of hyperthermic intraperitoneal docetaxel combined with cisplatin in patients with advanced-stage ovarian cancer

Zhi-yao You,Hui Li,Miao-fang Wu,Yanfang Ye,Li-juan Wang,Zhongqiu Lin,Jing Li 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.1

Objective: To identif y the maximum tolerated dose (MTD) of docetaxel combined with afixed dose of cisplatin (75 mg/m2) delivered as hyperthermic intraperitoneal chemotherapy(HIPEC) in patients with ovarian cancer. Methods: In this phase I trial, a time-to-event Bayesian optimal inter val design was used. Docetaxel was given at a starting dose of 60 mg/m2 and was increased in 5 mg/m2 incrementsuntil the MTD was determined or the maximum dose level of 75 mg/m2 was reached. The dose-limiting toxicity (DLT) rate was set at 25%, with a total sample size of 30 patients. HIPEC wasdelivered immediately following debulking surger y at a target temperature of 43°C for 90 minutes. Results: From August 2022 to November 2022, 30 patients were enrolled. Among thepatients who received a dose of docetaxel ≤65 mg/m2, no DLT was reported. DLTs wereobser ved in one patient who received 70 mg/m2 docetaxel (grade 3 anaemia) and in threepatients who received 75 mg/m2 docetaxel (one case of grade 3 anaemia, one case of grade3 hepatic impairment and one case of grade 4 thrombocytopenia). Patients treated withdocetaxel 75 mg/m2 in combination with cisplatin 75 mg/m2 had an estimated DLT rate of25%, which was the closest to the target DLT rate and was therefore chosen as the MTD. Conclusion: Docetaxel, in combination with a fixed dose of cisplatin (75 mg/m2), can be usedsafely at intraperitoneal doses of 75 mg/m2 in ovarian cancer patients who received HIPEC(43°C, 90 minutes) following debulking surger y. Trial Registration: ClinicalTrials.gov Identifier: NCT05410483