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      • KCI등재

        Two New Species of Placolecis (Lichenized Ascomycota) from China

        ( An Cheng Yin ),( Xin Yu Wang ),( Dong Liu ),( Yan Yun Zhang ),( Mei Xia Yang ),( Li Juan Li ),( Li Song Wang ) 한국균학회 2019 Mycobiology Vol.47 No.4

        Two new species of the lichen genus Placolecis are discovered in China, namely P. kunmingensis An. C. Yin & Li S. Wang and P. sublaevis An. C. Yin & Li S. Wang. The new combination P. loekoesiana (S.Y. Kondr., Farkas, J.J. Woo & Hur) An. C. Yin is proposed. Placolecis kunmingensis is characterized by having simple, spherical or ellipsoid, hyaline spores, and pear-shaped pycnidia; while P. sublaevis can be distinguished by its thallus forming larger aggregations with slightly flattened lobes at the thallus margin, and urn-shaped pycnidia. Descriptions, a phylogenetic tree and a key are provided for all the known Placolecis species in China.

      • KCI등재
      • KCI등재

        High-resolution Anorectal Manometry in the Diagnosis of Functional Defecation Disorder in Patients With Functional Constipation: A Retrospective Cohort Study

        Yan Zhao,Xiaoyang Ren,Wen Qiao,Lei Dong,Shuixiang He,Yan Yin 대한소화기 기능성질환∙운동학회 2019 Journal of Neurogastroenterology and Motility (JNM Vol.25 No.2

        Background/Aims High-resolution anorectal manometry (HRAM) has been considered a first-line diagnostic tool for functional defecation disorder. However, clinical studies on HRAM used in constipation patients are very limited and few studies have reported the characteristics of anorectal pressure in Chinese patients. The aim of this study is to investigate the characteristics of motility data in a cohort of Chinese patients with functional constipation. Methods A total of 82 consecutive patients with functional constipation who underwent a standardized HRAM were retrospectively enrolled in this study. The functional defecation disorder was classified into Rao’s types. Results The mean age of 82 patients was 51 years (range, 16–83 years). Indications for anorectal manometry were functional constipation for all patients. The mean resting pressure was 69.2 ± 21.2 mmHg (range, 24.5–126.9 mmHg). The mean maximum squeezing pressure was 198.4 ± 75.6 mmHg (range, 54.2–476.9 mmHg). The mean length of the anal high pressure zone was 3.4 ± 1.0 cm (range, 0.6–4.9 cm). Sixty (73.2%) patients were diagnosed as functional defecation disorder. In attempted defecation, type I was most common (n = 24), followed by type II (n = 12), type III (n = 11), and type IV (n = 13) that were present on HRAM according to Rao’s classification. In all 60 patients with functional defecation disorder, 37 were women and 23 were men. Men were significantly more likely than women to have functional defecation disorder (92.0% vs 64.9%, P = 0.014). Conclusion HRAM could be used as a test for the diagnosis of functional defecation disorder and functional defecation disorder is common in Chinese patients with functional constipation.

      • KCI등재

        Effect of naphthalene quinoline and H2S on DBT hydrodesulfurization over unsupported NiMoW catalyst

        Changlong Yin,Haonan Zhang,Tongtong Wu,Zhuyan Wu,Kunpeng Li,Yan Kong,Chengwu Dong,Chenguang Liu 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.12

        Unsupported catalysts have attracted much attention for high activity in comparison with the traditional supported catalyst. Meanwhile, the clear structure of unsupported catalysts is helpful for the recognition of active phase for conducting the industry production. The NiMoW unsupported catalyst was prepared by hydrothermal synthesis and characterized by BET, XRD and HRTEM. The effects of naphthalene, quinoline and H2S on the hydrodesulfurization reactivity of dibenzothiophene (DBT) were investigated in both a batch autoclave and a continuous 10 ml fixed bed micro-reactor over NiMoW and supported catalyst for comparison. The results showed that the hydrogenation reaction and the hydrogenolysis reaction occurred on different active sites. For supported catalyst, the inhibition was relatively weaker, and the inhibition of the hydrodesulfurization pathway was much higher than the direct desulfurization pathway. Although unsupported catalyst was very sensitive to quinoline and H2S in this experiment, the HDS ratio on the unsupported catalyst was maintained at a high level above 99.7%, which is attributed to the very high active site density of unsupported catalysts.

      • KCI등재

        Economic Production of Probiotics from Kitchen Waste

        Chunhua Yin,Xue Dong,Le Lv,Zhi-Guo Wang,Qianqian Xu,Xiaolu Liu,Hai Yan 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.suppl1

        In the present work, a novel treatment method of kitchen waste for economic production of probiotics was investigated. This required the selection of suitable probiotic microorganisms. Based on the pure cultures of probiotic strains for the fermentation kitchen waste, 5 strains of microorganisms including 1 strain of Lactobacillus, 2strains of Bacillus, and 2 strains of yeast were selected,respectively. These probiotic microorganisms were mixed at the same ratio and cultured using the kitchen waste as culture medium at pH of 7.2 and temperature of 37oC. After 24 h, the total count of the viable cells reached 2.24×1010 CFU/g, which was higher than that obtained in any single probiotic strain pure culture. It was found that the presence of yeasts and Bacillus species enhanced the growth of Lactobacillus strain. Bench scale experiments were also done in a self-designed rotating drum type bioreactor. The experimental results indicate that there is a good possibility of utilizing kitchen waste for the economic production of probiotics.

      • KCI등재

        Preparation of environmentally friendly low‐cost mullite porous Ceramics and the effect of Waste Glass Powder on structure and mechanical Properties

        Wei Lian,Yan Liu,Wenjie Wang,Yangtao Dong,Sheng Wang,Zhenying Liu,Yin Liu 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.9 No.2

        Environmentally friendly low-cost porous ceramics are prepared with 98.2 wt% mining waste as the raw materials at 1180 °C. The glass powder forms liquid phase at high temperatures, promoting the densification of the materials. X-ray diffraction (XRD) results show that the formation of mullite is affected by sintering temperature and content of liquid phase. The enhancement in densification is verified by the scanning electron microscopy (SEM) analysis results. According to the evolution of pore structure, the effect of the glass powder on the structure is confirmed. The number ratio of pores of < 8 μm to those of 8 ~ 20 μm is varied from 7:2 to 2:7. The minimum apparent porosity is 31.22 %, while the maximum density and linear shrinkage are 1.75 g/cm 3 and 8.48 %, respectively. The flexural strength (three-point bending method) was increased from 7.47 MPa to 28.36 MPa, indicating that the addition of glass powder could increase mechanical properties of the porous ceramics. Therefore, solid wastes can be used as the resource to develop porous mullite ceramics.

      • SCIESCOPUSKCI등재
      • Immune Reconstitution of CD4<sup>+</sup>T Cells after Allogeneic Hematopoietic Stem Cell Transplantation and its Correlation with Invasive Fungal Infection in Patients with Hematological Malignancies

        Peng, Xin-Guo,Dong, Yan,Zhang, Ting-Ting,Wang, Kai,Ma, Yin-Jian Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

        Objective: To explore the immune reconstitution of $CD4^+T$ cells after allogeneic hematopoietic stem cell transplantation (Allo-HSCT) and its relationship with invasive fungal infection (IFI) in patients with hematological malignancies. Materials and Methods: Forty-seven patients with hematological malignancies undergoing Allo-HSCT in Binzhou Medical University Hospital from February, 2010 to October, 2014 were selected. At 1, 2 and 3 months after transplantation, the immune subpopulations and concentration of cytokines were assessed respectively using flow cytometry (FCM) and enzyme linked immunosorbent assay (ELISA). The incidence of IFI after transplantation and its correlation with immune reconstitution of $CD4^+T$ cells were investigated. Results: The number of $CD4^+T$ cells and immune subpopulations increased progressively after transplantation as time went on, but the subpopulation cell count 3 months after transplantation was still significantly lower than in the control group (p<0.01). In comparison to the control group, the levels of interleukin-6 (IL-6) and IL-10 after transplantation rose evidently (p<0.01), while that of transforming growth factor-${beta}$ (TGF-${beta}$) was decreased (p<0.01). There was no statistically significant difference level of interferon-${\gamma}$ (IFN-${\gamma}$) (p>0.05). The incidence of IFI was 19.2% (9/47), and multivariate logistic regression revealed that IFI might be related to Th17 cell count (p<0.05), instead of Th1, Th2 and Treg cell counts as well as IL-6, IL-10, TGF-${beta}$ and IFN-${\gamma}$ levels (p>0.05). Conclusions: After Allo-HSCT, the immune reconstitution of $CD4^+T$ cells is delayed and Th17 cell count decreases obviously, which may be related to occurrence of IFI.

      • Association Between the FAS/FASL Polymorphisms and Gastric Cancer Risk: A Meta-Analysis

        Tian, Jing,Pan, Feng,Li, Jing,Ma, Yan,Cen, Han,Pan, Hai-Feng,Pan, Yue-Yin,Ye, Dong-Qing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

        Objective: FAS/FASL gene promoter polymorphisms have been repeatedly associated with gastric cancer risk, but findings are inconclusive across studies. To address a more precise estimation of the relationship, a meta-analysis was performed. Methods: Data were collected from the Pubmed, Medline and EMBASE databases, with the last report up to 1 December, 2011. Crude ORs with 95% CIs were used to assess the strength of the association by (1) the additive, (2) the codominant, (3) the dominant, and (4) the recessive models. Results: A total of seven studies, including six studies on FAS -1377G>A polymorphism, five studies on FAS -670A>G polymorphism, and six studies on FASL -844T>C polymorphism, were identified in the current meta-analysis. Overall, an association of FAS -1377G>A (AA versus GG: OR = 1.313, 95% CI = 1.045-1.650, Ph = 0.347, $I^2$ = 10.8) and FASL -844T>C (CC versus TT: OR = 1.352, 95% CI = 1.043-1.752, Ph = 0.461, $I^2$ = 0.0) polymorphisms with gastric cancer was found in the codominant model. However, we did not detect any association between gastric cancer and the FAS -670A>G polymorphism. In the subgroup analysis by ethnicity, similar elevated risks were also observed in Asian population for FAS -1377G>A (AA versus GG: OR = 1.309, 95% CI = 1.041-1.646, Ph = 0.240, $I^2$ = 27.3) and FASL -844T>C (CC versus TT: OR = 1.420, 95% CI = 1.081-1.865, Ph = 0.524, $I^2$ = 0.0) polymorphisms. Conclusions: This meta-analysis indicated that FAS -1377G>A and FASL -844T>C polymorphisms might be associated with gastric cancer risk.

      • Diagnostic Value of Human Epididymis Protein 4 Compared with Mesothelin for Ovarian Cancer: a Systematic Review and Meta-analysis

        Lin, Jia-Ying,Qin, Jin-Bao,Li, Xiao-Yan,Dong, Ping,Yin, Bing-De Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

        Background and Purpose: Ovarian cancer is the leading cause of death among gynecologic cancers because of the lack of effective early detection methods. Accuracies of the human epididymis protein 4 (HE4) and mesothelin in detecting ovarian cancer have never been systematically assessed. The current systematic review aimed to tackle this issue. Methods: MEDLINE, EMBASE, and Cochrane databases were searched (September 1995-November 2011) for studies on the diagnostic performances of HE4 and mesothelin in differentiating ovarian cancer from other benign gynecologic diseases. QUADAS items were used to evaluate the qualities of the studies. Meta-DiSc software was used to handle data from the included studies and to examine heterogeneity. All included studies for diagnostic performance were combined with sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratios (DORs) with 95% confidence intervals (CIs), summary receiver operating characteristic (SROC) curves, and areas under the SROC curves (AUC). Results: A total of 18 studies and 3,865 patients were eligible for the final analysis. The pooled sensitivity estimates for HE4 (74.4%) were significantly higher than those for mesothelin (49.3%). The pooled specificity estimates for mesothelin (94.5%) were higher than those for HE4 (85.8%). The pooled DOR estimates for HE4 (26.22) were higher than those for mesothelin (24.01). The SROC curve for HE4 showed better diagnostic accuracy than that for mesothelin. The PLR and NLR of HE4 were 6.33 (95% CI: 3.58 to 11.18) and 0.27 (95% CI: 0.21 to 0.34), respectively. The PLR and NLR for mesothelin were 11.0 (95% CI: 6.21 to 19.59) and 0.51 (95% CI: 0.42 to 0.62), respectively. The combination of the two tumor markers or their combination with CA-125 increased sensitivity and specificity to different extents. Conclusion: The diagnostic accuracy of HE4 in differentiating ovarian cancer from other benign gynecologic diseases is better than that of soluble mesothelin-related protein. Combinations of two or more tumor markers show more sensitivity and specificity.

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