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      • KCI등재

        Depth tracking of occluded ships based on SIFT feature matching

        Yadong Liu,Yuesheng Liu,Ziyang Zhong,Yang Chen,Jinfeng Xia,Yunjie Chen 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.4

        Multi-target tracking based on the detector is a very hot and important research topic in target tracking. It mainly includes two closely related processes, namely target detection and target tracking. Where target detection is responsible for detecting the exact position of the target, while target tracking monitors the temporal and spatial changes of the target. With the improvement of the detector, the tracking performance has reached a new level. The problem that always exists in the research of target tracking is the problem that occurs again after the target is occluded during tracking. Based on this question, this paper proposes a DeepSORT model based on SIFT features to improve ship tracking. Unlike previous feature extraction networks, SIFT algorithm does not require the characteristics of pre-training learning objectives and can be used in ship tracking quickly. At the same time, we improve and test the matching method of our model to find a balance between tracking accuracy and tracking speed. Experiments show that the model can get more ideal results.

      • KCI등재

        Hospitalization Due to Asthma Exacerbation: A China Asthma Research Network (CARN) Retrospective Study in 29 Provinces Across Mainland China

        Jiangtao Lin,Bin Xing,Huaping Tang,Lan Yang,Yadong Yuan,Yuhai Gu,Ping Chen,Xiaoju Liu,Jie Zhang,Huiguo Liu,Changzheng Wang,Wei Zhou,Dejun Sun,Yiqiang Chen,Zhuochang Chen,Mao Huang,Qichang Lin,Chengpin 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.3

        Purpose: Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is indispensable. This study aimed to investigate the clinical characteristics and outcomes of such patients. Methods: A retrospective study was conducted on patients hospitalized for asthma exacerbation in 29 hospitals of 29 regions in mainland China during the period 2013 to 2014. Demographic features, pre-admission conditions, exacerbation details, and outcomes were summarized. Risk factors for exacerbation severity were analyzed. Results: There were 3,240 asthmatic patients included in this study (57.7% females, 42.3% males). Only 28.0% used daily controller medications; 1,287 (39.7%) patients were not currently on inhaled corticosteroids. Acute upper airway infection was the most common trigger of exacerbation (42.3%). Patients with severe to life-threatening exacerbation tended to have a longer disease course, a smoking history, and had comorbidities such as hypertension, chronic obstructive pulmonary disease (COPD), and food allergy. The multivariate analysis showed that smoking history, comorbidities of hypertension, COPD, and food allergy were independent risk factors for more severe exacerbation. The number of patients hospitalized for asthma exacerbation varied with seasons, peaking in March and September. Eight patients died during the study period (mortality 0.25%). Conclusions: Despite enhanced education on asthma self-management in China during recent years, few patients were using daily controller medications before the onset of their exacerbation, indicating that more educational efforts and considerations are needed. The findings of this study may improve our understanding of hospital admission for asthma exacerbation in mainland China and provide evidence for decision-making.

      • KCI등재

        STYXL1 promotes proliferation and epithelial mesenchymal transition of gastric cancer cells via activating the PI3K/AKT pathway

        Chen Silu,Yu Weiyan,Li Ziyue,Wang Yadong,Peng Bo 대한독성 유전단백체 학회 2024 Molecular & cellular toxicology Vol.20 No.2

        Background Gastric cancer (GC) is a common and grievous disorder with high heterogeneity. Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1), a pseudophosphatase without catalytic activity, plays a important roles in cellular pathways and various cancers. However, its role and mechanism in GC remain unclear. Objectives This study aimed to explore the role and possible mechanism of STYXL1 in GC cells. Results The results showed that STYXL1 expression was elevated in GC. Both loss- and gain-of-function results showed that STYXL1 enhanced cell viability, colony formation, cell invasion and migration, and the protein expression of BCL-2 and Vimentin, but reduced the apoptosis rate and the protein level of BAX, cleaved caspase 3 and E-Cadherin in vitro. Mechanically, the levels of p-PI3K/PI3K and p-AKT/AKT were observably elevated by overexpression of STYXL1, and markedly reduced by silencing of STYXL1 in both SNU-1 and HGC-27 cells. Conclusion STYXL1 promoted cell growth, migration, invasion and EMT with decreased apoptosis, which was closely related with the activation of PI3K/AKT pathway in GC.

      • KCI등재

        Differential Hrd1 Expression and B-Cell Accumulation in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis With Nasal Polyps

        Kun Chen,Miaomiao Han,Mengyao Tang,Yadong Xie,Yuting Lai,Xianting Hu,Jia Zhang,Jun Yang,Huabin Li 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.6

        Purpose: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unexplored. This study aimed to examine Hrd1 expression and B-cell accumulation and their possible roles in CRSwNP. Methods: Quantitative real-time polymerase chain reaction, immunohistochemistry, enzyme-linked immunosorbent assay and Western blotting were used to assess gene and protein expression in nasal tissue extracts. Cells isolated from nasal tissues and peripheral blood mononuclear cells were characterized by flow cytometry. Local antibody production was measured in tissue extracts with a Bio-Plex assay. Additionally, changes in Hrd1 expression in response to specific inflammatory stimuli were measured in cultured dispersed polyp cells. Results: Nasal polyps (NPs) from patients with eosinophilic CRSwNP (ECRS) had increased levels of Hrd1, B-cells and plasma cells compared with NPs from patients with non-eosinophilic CRSwNP (non-ECRS) or other control subjects (P < 0.05). The average Hrd1 levels in B-cells in NPs from ECRS patients were significantly higher than those from non-ECRS patients and control subjects (P < 0.05). NPs also contained significantly increased levels of several antibody isotypes compared with normal controls (P < 0.05). Interestingly, Hrd1 expression in cultured polyp cells from ECRS patients, but not non-ECRS patients, was significantly increased by interleukin-1β, lipopolysaccharide and Poly(I:C) stimulation, and inhibited by dexamethasone treatment (P < 0.05). Conclusions: Differential Hrd1 expression and B-cell accumulation between the ECRS and non-ECRS subsets suggests that they can exhibit distinct pathogenic mechanisms and play important roles in NP.

      • KCI등재

        Electrophoresis-deposition construction of covalently bonded interface material with enhanced thermal conductivity

        Fu Hao,Chen Guang,Gao Junchang,Wu Yadong,Tao Xin,Huang Youguo 한국탄소학회 2024 Carbon Letters Vol.34 No.5

        The thermal conductivity (TC) of graphene-based/metal composites is currently not satisfactory because of the existence of large interfacial thermal resistance between graphene and metal originating from the strong scattering of phonons. In this work, 6063Al-alloy-based reduced graphene oxide (rGO) composite with strong covalent bonds interface was prepared via self-assembly, reduction, and electrophoresis-deposition processes by using 3-aminopropyl triethoxysilane (APTS) as a link agent. Structural characterizations confirmed the successful construction of strong Al-O-Si-O-C covalent bonds in the as-prepared 6063Al-Ag-APTS-rGO composite, which can promote the transfer of phonons in the interface. Benefiting from the unique structure, 6063Al-Ag-APTS-rGO (214.1 W/mK) showed obviously higher cross-plane TC than 6063Al (195.6 W/mK). Comparative experiments showed that 6063Al-Ag-APTS-rGO has better cross-plane TC than 6063Al/Ag/APTS/rGO (196.6 W/mK) prepared via physical mixing of stirring process, evidencing the significance of electrophoresis-deposition (EPD) process on constructing strong covalent bonds for improving the heat dissipation performance. Besides, the effects of different rGO contents and test temperature on the TC of the composites and their corrosion resistance were also discussed. This work demonstrated a feasible strategy for the construction of metal–carbon interface composite with improved thermal performance.

      • KCI등재

        The effects of cigarettes and alcohol on intestinal microbiota in healthy men

        Lin Renbin,Zhang Yawen,Chen Luyi,Qi Yadong,He Jiamin,Hu Mengjia,Zhang Ying,Fan Lina,Yang Tao,Wang Lan,Si Misi,Chen Shujie 한국미생물학회 2020 The journal of microbiology Vol.58 No.11

        Human intestinal microbiota is affected by the exogenous microenvironment. This study aimed to determine the effects of cigarettes and alcohol on the gut microbiota of healthy men. In total, 116 healthy male subjects were enrolled and divided into four groups: non-smoking and non-drinking (Group A), smoking only (Group B), drinking only (Group C), and smoking and drinking combined (Group D). Fecal samples were collected and sequenced using 16S rRNA to analyze the microbial composition. Short-chain fatty acid (SCFAs) levels in feces were determined by gas chromatography. We found that cigarette and alcohol consumptions can alter overall composition of gut microbiota in healthy men. The relative abundances of phylum Bacteroidetes and Firmicutes and more than 40 genera were changed with cigarette and alcohol consumptions. SCFAs decreased with smoking and alcohol consumption. Multivariate analysis indicated that when compared with group A, group B/C/D had higher Bacteroides, and lower Phascolarctobacterium, Ruminococcaceae_ UCG-002, Ruminococcaceae_UCG-003, and Ruminiclostridium_ 9 regardless of BMI and age. Additionally, the abundance of Bacteroides was positively correlated with the smoking pack-year (r = 0.207, p < 0.05), the abundance of predicted pathway of bacterial toxins (r = 0.3672, p < 0.001) and the level of carcinoembryonic antigen in host (r = 0.318, p < 0.01). Group D shared similar microbial construction with group B, but exerted differences far from group C with lower abundance of Haemophilus. These results demonstrated that cigarette and alcohol consumption separately affected the intestinal microbiota and function in healthy men; furthermore, the co-occurrence of cigarette and alcohol didn’t exacerbate the dysbiosis and cigarette played the predominated role on the alteration.

      • KCI등재

        A prototype of the SiPM readout scintillator neutron detector for the engineering material diffractometer of CSNS

        Qian Yu,Bin Tang,Chang Huang,Yadong Wei,Shaojia Chen,Lin Qiu,Xiuku Wang,Hong Xu,Zhijia Sun,Guangyou Wei,Mengjiao Tang 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.3

        A high detection efficiency thermal neutron detector based on the 6LiF/ZnS(Ag) scintillation screens,wavelength-shifting fibers (WLSF) and Silicon photomultiplier (SiPM) readout is under development atChina Spallation Neutron Source (CSNS) for the Engineering Material Diffractometer (EMD).A prototypewith a sensitive volume of 180mm 192mm has been built. Signals from SiPMs are processed by the selfdesignApplication Specific Integrated Circuit (ASIC). The performances of this detector prototype are as follows: neutron detection efficiency could reach50.5% at 1 Å, position resolution of 3, the dark count rate <0.1Hz, the maximum count rate >200KHz. Such detector prototype could be an elementary unit for applications in the EMD detector arrays.

      • KCI등재

        Synthesis and Antitumor Activity of Novel Diaryl Ether Hydroxamic Acids Derivatives as Potential HDAC Inhibitors

        Yong Zhu,Tao Lu,Xin Chen,Zeng Wu,Yixuan Zheng,Yadong Chen,Weifang Tang 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.10

        A series of diaryl ether hydroxamic acids were synthesized for the first time and evaluated for the HDAC biology and antiproliferative activity. The structures of these new hydroxamic acids derivatives were confirmed by IR, 1H-NMR and mass spectrum. Some of these compounds showed micro molar activity in the HDAC inhibitory assay and against four cancer cell lines.

      • KCI등재

        Influence of Molecular Weight on the Dielectric and Energy Storage Properties of Poly(vinylidene fluoride)

        Yuetao Zhao,Wenyao Yang,Yujiu Zhou,Yan Chen,Yajie Yang,Jianhua Xu,Yadong Jiang 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.6

        The molecular weight shows great influence on dielectricand energy storage performance of poly(vinylidenefluoride) (PVDF) films and related devices. In this letter,the influences of molecular weight on the dielectric andenergy storage properties of PVDF films were studied. Ithas been found that, under a 1000 kV/cm electric field,the low-molecular-weight PVDF film presents a muchhigher energy storage efficiency as high as 80.10%,nearly three times as much as the high-molecular-weightPVDF film. Moreover, the low-molecular-weight PVDFfilm also shows high resistivity, representing an order ofmagnitude improvement over the high-molecular-weightPVDF film, which is more desirable and promising forhigh performance pulse discharge capacitor application.

      • KCI등재

        Preparation and photoluminescence properties of the Eu2+, Sm3+ co-doped Li2SrSiO4 phosphors

        Lijuan Liu,Panli You,Guangfu Yin,Xiaoming Liao,Zhongbing Huang,Xianchun Chen,Yadong Yao 한국물리학회 2012 Current Applied Physics Vol.12 No.4

        A series of Eu2+ and Sm3+ co-doped Li2SrSiO4 phosphors are prepared by the high temperature solidstate reaction. The morphology, structure and spectroscopic properties of the prepared samples are characterized by scanning electron microscopy, X-ray diffraction, diffuse reflection spectra, photoluminescence spectra and electron paramagnetic resonance spectra, respectively. The effect of Sm3þdoping concentration on the photoluminescence intensity of the prepared samples is also investigated. The results indicate that the crystal structure of Li2SrSiO4 is not changed with the Eu2+, Sm3+ co-doping. The spherical-like particle size of the obtained product is about 20-30 nm in diameter. When the Sm3+ concentration is 0.3 mol% and the Eu2+ concentration is 0.7 mol%, the phosphors show the maximum emission intensity, which is 50% higher than that of Eu2+ doped Li2SrSiO4. Excited at 420 nm, the phosphor presents a single broad emission band peaking at 558 nm, which is ascribed to the 4f65d1 / 4f7 transitions of Eu2+ and 4G5/2 / 6H5/2 and 4G5/2 / 6H7/2 transitions of Sm3+. The Commission International de I0Eclairage chromaticity coordinates of Li2SrSiO4:0.7 mol% Eu2+, 0.3 mol%Sm3+ are x = 0.28, y = 0.28. A series of Eu2+ and Sm3+ co-doped Li2SrSiO4 phosphors are prepared by the high temperature solidstate reaction. The morphology, structure and spectroscopic properties of the prepared samples are characterized by scanning electron microscopy, X-ray diffraction, diffuse reflection spectra, photoluminescence spectra and electron paramagnetic resonance spectra, respectively. The effect of Sm3þdoping concentration on the photoluminescence intensity of the prepared samples is also investigated. The results indicate that the crystal structure of Li2SrSiO4 is not changed with the Eu2+, Sm3+ co-doping. The spherical-like particle size of the obtained product is about 20-30 nm in diameter. When the Sm3+ concentration is 0.3 mol% and the Eu2+ concentration is 0.7 mol%, the phosphors show the maximum emission intensity, which is 50% higher than that of Eu2+ doped Li2SrSiO4. Excited at 420 nm, the phosphor presents a single broad emission band peaking at 558 nm, which is ascribed to the 4f65d1 / 4f7 transitions of Eu2+ and 4G5/2 / 6H5/2 and 4G5/2 / 6H7/2 transitions of Sm3+. The Commission International de I0Eclairage chromaticity coordinates of Li2SrSiO4:0.7 mol% Eu2+, 0.3 mol%Sm3+ are x = 0.28, y = 0.28.

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