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선천성 자궁경폐쇄및 선천성 부분 질폐쇄진을 동반한 1례
정영희(YH Jung),김재수(JS Kim),허동은(DE Hur) 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.6
15세 여성에서 발생한 혈 , 자궁혈 , 부분 을 동반한 소한 선천성 자궁 1례를 치 하였기에 한 문 과 함께 보고하는 바이다. Congenital atresia of the uterine cervix in the presence of functioning endome- trium is a rare and very troublesome congenital anomaly with potentially serious sequelae when surgical management is delayed. Now we present a care of congenital atresia of the uterine cerivx with partial vaginal atresia, hematometra and Lt. hematosalpinx, who received. simple total hysterectomy, Lt. adnexcetomy and vaginoplasty, and discuss the embryology, clinical symptoms, and management.
거대 Sertoli-Leydig Cell Tumor의 1 예
정영희(YH Jung),김재수(JS Kim),허동은(DE Hur) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.8
The Sertoli-Leydig cell(S-L) tumor is a gonadal tumor of sexcordstromal type in which the components to a greater or lesser extent recapitulate the cells of the testis at various stages of development and is said to be approximately one-fifth as common as the granulosa theca cell tumor, and accounts for less than 0.4% of all ovarian tumors. We experienced a giant S-L tumor and so we present it with brief review of concerning literature.
정영희(YH Jung),조갑수(KS Cho),허동은(DE Hur) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.1
It was posturated that measurement of femur length could also be used for assessing fetal age. The relation between fetal femur length and gestational age was determined by a analysis of 171 fetuses (13-23 weeks) using real-time Ultrasound. Results summarized were as follows: 1. The high correlation was observed between fetal length and gestational age, and correlation coefficiency (r) was 0.99 in value (p<0.001). 2. The regression equation for this data was gestational age (Weeks)=3.48(fetal femur length) + 8.41. The measurement of fetal femur length by Ultrasound is appeared to be as accurate as that of biparietal diameter in predicting the gestational age and it may be useful as an additional measurement to ensure the accuracy of estimated fetal age.
정혁,최상준,송창훈,김영호 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.9
Nonimmune hydrops fetals is defined as generalized edema of the fetal soft tissue in utero and may be associated with effusion in the serous cavities without hematologic evidence of isoimmunization. The most common demonstrable causes are cardiac anomalies, followed by chromosomal disorders, congenital malformations, α-thalassemia, and the twin-twin transfu-sion syndrome. We have experienced a case of nonimmune hydrops fetalis in identical twin which caused by congenital mitral valve insufficiency and disappeared spontaneously at 35 wks. Now we report a case of nonimmune hydrops fetalis that slowly and spontaneously imp-roved without interventions with a brief review of related literatures.
정혁,한세준,최상준,송창훈,임성철,김영호,류경철,여인동 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.4
저자 등은 경우 난소의 악성 중배엽성 혼재성 종양을 경험하였으며, 환자는 수술 후 병기 Ⅲc로 한차례 복합 화학요법 시행 후 6 개월째 생존중이다. Malignant mixed m llerian tumor (MMMT) of the ovary is a rare tumor with dismal prognosis. MMMT by definition contain epithelial and mensenchymal elements, both of which are histologically malignant. They are classified as endometrial lesions because the glands often appear endometrial-like and the stroma resemble that of the endometrium. The disease is usually advanced (Stage Ⅲ) when diagnosed and thus provides a difficult challenge to any postoperative therapy. We experienced a case of MMMT of ovary with neuroectodermal differentiation in 69 years-old multiparous women and report our experience with a brief review of literature.
상피성 난소암에서 면역화학적 염색에 의한 bc1-2와 p53 유전자발현에 관한 연구
정혁,한세준,최상준,송창훈,임성철,김영호,류경철 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.11
Bcl-2 and p53, two proteins, have implicated in apoptosis and among them p53 is known as adverse prognostic factor in a number of tumors. But it is variable in different tissues whe-ther bcl-2 expression and its role are related in the prognosis. The present study was aimed to find the role of bcl-2 and p53 in prognosis of epithelial ovarian cancer. We examined 32 epithelial ovarian cancer specimens of different histologic types and stages by immunohistochemical staining. Bcl-2 protein expression was found in 11/32 epithelial ovarian cancers and it was related in survival(p=0.0038) and p53 accumulation was found in 17/32 epithelial ovarian cancers but it was not rrelated in survival(p=0.0717). But bcl-2 expression and p53 accumulation were not related to the FIGO stages(p>0.05). The analysis of the postoperative course of 32 patients showed that survival depended on the FIGO stages(p=0.001 2) and the histologic type(p=0.009). However, bcl-2 immunohistochemistry identified a subgroup of patients with p53 and bcl-2 positive carcinomas who had not a statistically better outcome(p=0.082) than patients with p53 positive and bcl-2 negative carcinomas. Thus our observations point to different molecular alterations possibly underlying phenotypic diversity of ovarian carcinomas and provide clues for a better understanding of tumor progression in these neoplasms.