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Fu Xin,Jie Zhang,Zhiyuan Chen,Xiaorong Du 기술경영경제학회 2016 ASIAN JOURNAL OF TECHNOLOGY INNOVATION Vol.24 No.3
This paper aims to fill the gap in the extensive literature on the results of interaction betweenpublic and private R&D expenditures. Two types of public R&D subsidies, the appropriationsand loan interest, are investigated in the effect of public subsidies by applying for a uniquemicro data set of Chinese manufacturing firms combined with the Innovation Fund forSmall and Medium Technology-based Firms (Innofund). The results are consistent with theprediction that loan interest subsidies based on more competitive selective system are moreeffective for the public R&D subsidies than the appropriations. Firms’ heterogeneity,measured by state-owned enterprises (SOEs) and private-owned enterprises (POEs), is testedfor the different impact of public subsidies on corporate R&D investment. The results showthat the crowding-in effect is mainly driven by POEs, not by SOEs, which confirms thetheoretical assumption by Aghion and Tirole that the agency problem play a dominant rolein corporate R&D activities. An improved econometric method, combined propensity scorematching with difference-in-differences estimation strategy, is applied for correcting theselection bias. Our results are robust to different matching techniques.
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OsBAK1 is involved in rice resistance to Xanthomonas oryzae pv. oryzae PXO99
Hualan Liao,Xiaorong Xiao,Xiuqiong Li,Yan Chen,Xiumei Fu,Daozhe Lin,Xiaolei Niu,Yinhua Chen,Chaozu He 한국식물생명공학회 2016 Plant biotechnology reports Vol.10 No.2
OsBAK1 gene belongs to a receptor like kinase gene family in rice and shares a highly conserved gene structure and sequence homology with Arabidopsis thaliana BAK1 gene. To investigate the role of OsBAK1 in rice immunity, the full-length cDNA of OsBAK1 was isolated by RT-PCR and the transgenic rice lines (over expression and RNA-interference lines) were generated using Agrobacterium-mediated transformation. The expression level of OsBAK1 was determined by q-PCR in overexpression and RNAi transgenic rice lines. Based on quantitative polymerase chain reaction (q-PCR) results, two overexpression lines and two RNAi lines were evaluated in bioassays for resistance to Xanthomonas oryzae pv. oryzae PXO99, the causal agent of rice bacterial blight disease. Pathogenicity bioassays showed overexpression OsBAK1 lines exhibited resistance to blight disease whereas OsBAK1 RNAi lines promoted susceptibility. Besides, OsBAK1 can complement the function of AtBAK1 in Arabidopsis bak1 protoplast, activating FRK1 expression, a marker gene in PTI signaling pathway, after treatment by flg22. Furthermore, the transcriptional level of OsBAK1 was induced significantly in rice by defense signaling molecules such as salicylic acid, jasmonic acid, and PXO99 inoculation. Our results illustrated OsBAK1 positively regulates plant defense against rice bacterium pathogen Xanthomonas oryzae pv. oryzae PXO99.
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EXPLORE THE IMPACT OF TOURIST-TO-TOURIST ON TOURISM EXPERIENCE: A SELF-DISCLOSURE PERSPECTIVE
Meng Zhang,Hongxia Lin,Xiaorong Fu 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07
Human beings are intrinsically social. How social interaction among tourists affect their experience remains under-represented. Drawing on S-O-R theory, social integration theory and social penetration theory, this study proposes and empirically tests a conceptual model that integrates self-disclosure, perceived cohesion, perceived intimacy, tourist engagement and tourist satisfaction with the experience. Also, the tie strength is theorized as a moderator in the relationship between self-disclosure and perceived cohesion as well as perceived intimacy. A field experiment was undertaken to collect data. The results from the structural analysis suggest that self-disclosure influences perceived cohesion and perceived intimacy, which in turn influence their engagement and satisfaction with tourism experience. Moreover, the initial tie strength has moderation effect on the relationship between self-disclosure and perceived cohesion as well as perceived intimacy. Overall, findings of this study contributes to the development of tourism experience research from the perspective of tourist-to-tourist interaction, and broadens the research on tourist engagement. Discussions and implications for tourism operators, limitations, and suggestions for future research are also provided.
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Three-Month Follow-Up Study of Survivors of Coronavirus Disease 2019 after Discharge
Liang Limei,Yang Bohan,Jiang Nanchuan,Fu Wei,He Xinliang,Zhou Yaya,Ma Wan-Li,Wang Xiaorong 대한의학회 2020 Journal of Korean medical science Vol.35 No.47
Background: Most patients including health care workers (HCWs) survived the coronavirus disease 2019 (COVID-19), however, knowledge about the sequelae of COVID-19 after discharge remains limited. Methods: A prospectively observational 3-month follow-up study evaluated symptoms, dynamic changes of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) IgG and IgM, lung function, and high resolution computed tomography (HRCT) of survivors of COVID-19 after discharge at Wuhan Union Hospital, China. Results: Seventy-six survivors (55 females) with a mean age of 41.3 ± 13.8 years were enrolled, and 65 (86%) were HCWs. A total of 69 (91%) patients had returned to their original work at 3-months after discharge. Most of the survivors had symptoms including fever, sputum production, fatigue, diarrhea, dyspnea, cough, chest tightness on exertion and palpitations in the three months after discharge. The serum troponin-I levels during the acute illness showed high correlation with the symptom of fatigue after hospital discharge (r = 0.782; P = 0.008) and lymphopenia was correlated with the symptoms of chest tightness and palpitations on exertion of patients after hospital discharge (r = −0.285, P = 0.027; r = −0.363, P = 0.004, respectively). The mean values of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC, total lung capacity and diffusion capacity were all normal (> 80% predicted) and lung HRCTs returned to normal in most of the patients (82%), however, 42% of survivors had mild pulmonary function abnormalities at 3-months after discharge. SARS-CoV-2 IgG turned negative in 11% (6 of 57 patients), 8% (4 of 52 patients) and 13% (7 of 55 patients), and SARS-CoV-2 IgM turned negative in 72% (41 of 57 patients), 85% (44 of 52 patients) and 87% (48 of 55 patients) at 1-month, 2-months and 3-months after discharge, respectively. Conclusion: Infection by SARS-CoV-2 caused some mild impairments of survivors within the first three months of their discharge and the duration of SARS-CoV-2 antibody was limited, which indicates the necessity of long-term follow-up of survivors of COVID-19.
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