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Pu-erh Tea Powder Preventive Effects on Cisplatin-Induced Liver Oxidative Damage in Wistar Rats
Zheng, Xiao-Nan,Wang, Xiao-Wen,Li, Li-Ya,Xu, Zi-Wei,Huang, Hsin-Yi,Zhao, Jin-Sheng,Zhang, Duo,Yin, Xu,Sheng, Jun,Tang, Jin-Tian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17
Background: Chemotherapy is one of the major means for control of malignancies, with cisplatin (CDDP) as one of the main agents, widely used for the treatment of various malignant solid tumors. However, prevention of hepatotoxicity from cisplatin is one of the urgent issues in cancer chemotherapy. In this study, we aimed to investigate the effects of pu-erh tea on hepatotoxicity through body weight and tissue antioxidant parameters like, liver coefficient, serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST), superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), malondialdehyde(MDA) and glutathione (GSH) levels, and light microscopic evaluation by histological findings. Materials and Methods: The rats were randomly divided into five groups: Control (n=10), cisplatin (3 mg/kg p.i., n=10), cisplatin+pu-erh (0.32 g/kg/day i.g., n=10), cisplatin+pu-erh (0.8 g/kg/day i.g., n=10) and cisplatin+pu-erh (1.6 g/kg/day i.g., n=10). Pu-erh tea powder was administrated for 31 consecutive days. The rats were sacrificed at the end on the second day after a single dose of cisplatin treatment for measuring indices. Results: Pu-erh tea powder exhibited a protective effect by decreasing MDA and GSH and increasing the SOD and GSH-PX levels and GSH-PX/MDA ratio in camparison with the control group. Besides, pu-erh tea was also able to alleviate the pathological damage to some extent. Conclusion: Pu-erh tea powder is protective against cisplatin-induced liver oxidative damages, especially at the medium dosage (0.8 g/kg/d).
Xiao-Ling Zheng,Zhi-Qiang Xiong,Jie-Qun Wu 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.1
Detection of the number of vegetative cells and endospores is necessary for quality control during the production of orally administered probiotic Bacillus licheniformis-containing tablets (BCT). However, there is no standard method for the rapid detection of vegetative cells and endospores in China. In this study, a simple flow cytometry (FCM) method was used to monitor the population dynamics of BCT. Using a specific fluorescent stain, SYBR green I, flow cytometric analysis could easily differentiate two morphological states of B. licheniformis. Compared with plate count assay (PCA) for determining the number of vegetative cells and endospores, the percentage of endospores determined by FCM was ~10% higher than that by PCA. Advantages of the FCM method over conventional methods include lower labor work, shorter detection time, and higher accuracy. Therefore, this simple FCM method could be a practical tool for monitoring quality control during the production of probiotic BCT
Baijiu (白酒), Chinese liquor: History, classification and manufacture
Xiao-Wei Zheng,Bei-Zhong Han 한국식품연구원 2016 Journal of Ethnic Foods Vol.3 No.1
Baijiu (白酒) is a traditional fermented alcoholic drink originating in China, which is typically obtained by natural fermentation. It has a high reputation and constitutes an important part of Chinese dietary profile. The production of baijiu involves five major steps, materials preparation, daqu (大曲) making, alcoholic fermentation, distillation, and aging. There is a range of baijiu with different flavors and corresponding names. Baijiu can be categorized according to the production techniques (solid state and semi-solid state), types of starter [daqu, xiaoqu (小曲), and fuqu (麸曲)] and product flavor (strong, light, sauce, etc.). different types of baijiu have their home microbiota and flavor because of their distinct production techniques. In this review, we discuss the critical steps and the microorganisms involved in the production of different types of baijiu. Although baijiu contains alcohol, it has been proven that it plays a significant role in the heath and quality of peoples' lives.
Zheng-Xi Zhang,Kun Feng,Xian-Jin Sui,Wen-Shu Wang,Lin Wang,Dong-Hong Wang,Xiao-Min Luo,Xiao-Fei Chen 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.12
Four new acylated triterpene glycosides with aliphatic chains (4–7) as well as five known triterpenoids were isolated from the flower buds of Staphylea bumalda with bioassay guidance. Their structures were determined on the basis of spectral techniques, including IR, 1D and 2D NMR, and HR-APCI-MS. Most compounds (except 8) were isolated from S. bumalda for the first time. Additionally, the neuroprotective effects of 1 and 4–9 on suckling rat primary cultured hippocampal neurons against H2O2-induced injury were evaluated in vitro. The four new triterpenoids (4–7) showed neuroprotective effects, which increased the cell viability to over 74% at different concentrations, which was higher than the negative control (59%), while compounds 1 and 8–9 exhibited cytotoxic activity.
Xiao-Xia Zheng,Peng Peng 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
As the core component of transmission systems, converters are very prone to failure. To improve the accuracy of fault diagnosis for wind power converters, a fault feature extraction method combined with a wavelet transform and compressed sensing theory is proposed. In addition, an improved AdaBoost-SVM is used to diagnose wind power converters. The three-phase output current signal is selected as the research object and is processed by the wavelet transform to reduce the signal noise. The wavelet approximation coefficients are dimensionality reduced to obtain measurement signals based on the theory of compressive sensing. A sparse vector is obtained by the orthogonal matching pursuit algorithm, and then the fault feature vector is extracted. The fault feature vectors are input to the improved AdaBoost-SVM classifier to realize fault diagnosis. Simulation results show that this method can effectively realize the fault diagnosis of the power transistors in converters and improve the precision of fault diagnosis.
Zheng, Chun-Long,Qiu, Chen,Shen, Mei-Xiao,Qu, Xiao,Zhang, Tie-Hong,Zhang, Ji-Hong,Du, Jia-Jun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
Background: The vascular endothelial growth factor family has been implicated in tumorigenesis and metastasis. The prognostic value of each vascular endothelial growth factor family member, particular VEGF/VEGFR co-expression, in patients with non-small lung cancer remains controversial. Materials and Methods: Relevant literature was identified by searching PubMed, EMBASE and Web of Science. Studies evaluating expression of VEGFs and/or VEGFRs by immunohistochemistry or ELISA in lung cancer tissue were eligible for inclusion. Hazard ratios (HRs) and 95% confidence intervals (CIs) from individual study were pooled by using a fixed- or random-effect model, heterogeneity and publication bias analyses were also performed. Results: 74 studies covering 7,631 patients were included in the meta-analysis. Regarding pro-angiogenesis factors, the expression of VEGFA (HR=1.633, 95%CI: 1.490-1.791) and VEGFR1 (HR=1.924, 95%CI: 1.220-3.034) was associated separately with poor survival. Especially, VEGFA over-expression was an independent prognostic factor in adenocarcinoma (ADC) (HR=1.775, 95%CI: 1.384-2.275) and SCC (HR=2.919, 95%CI: 2.060-4.137). Co-expression of VEGFA/VEGFR2 (HR=2.011, 95%CI: 1.405-2.876) was also significantly associated with worse survival. For lymphangiogenesis factors, the expression of VEGFC (HR=1.611, 95%CI: 1.407-1.844) predicted a poor prognosis. Co-expression of VEGFC/VEGFR3 (HR=2.436, 95%CI: 1.468-4.043) emerged as a preferable prognostic marker. Conclusions: The expression of VEGFA (particularly in SCC and early stage NSCLC), VEGFC, VEGFR1 indicates separately an unfavorable prognosis in patients with NSCLC. Co-expression VEGFA/VEGFR2 is comparable with VEGFC/VEGFR3, both featuring sufficient discrimination value as preferable as prognostic biologic markers.
Xiao-Kang Li,Da-Feng Zheng,Tao Zheng,Xu-Liang Lin,Hong-ming Lou,Xueqing Qiu 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.49 No.-
The dispersion ability of polycarboxylate ether (PCE) in fresh concrete is much impeded by clayimpurities. To improve the dispersion of PCE in the clay-contained concrete, lignin-based polyoxy-ethylene ether (PEG-grafted-lignin) was synthesized through polyethylene glycol (PEG) grafted to kraftlignin (KL). The results showed that PEG-grafted-lignin increased thefluidity of MMT-contained cementpaste when combined with PCE. It improved the rheological properties of MMT-contained cement pasteby reducing the yield stress and the rheological behavior index. The adsorption of PEG-grafted-lignin onMMT was more quickly than KL and the equilibrium adsorption amount was 31.43 mg/g at an initialconcentration of 100 mg/L. XRD revealed that PEG-grafted-lignin had inserted into the interlayerstructure of MMT, while DLS disclosed the spatial effect of PEG-grafted-lignin was much stronger thanPCE. This study put forward a new method in the anti-sludge study of PCE.
Xiao-Zheng Jin,Guang-Hong Yang,Wei-Wei Che 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.6
This paper utilizes the adaptive technique to design a class of active synchronizing master-slave large scale systems against imperfect actuators and networked interconnections with bias faults and signal attenuations, respectively. Without the requirement of knowledge of eventual faulty factors of bias-actuators on systems, and attenuation factors of connected networks, an adaptive mechanism is de-signed to estimate each unknown faulty factor on-line for constructing a class of distributed adaptive controllers. Then based on the adaptive adjustment parameters and Lyapunov stability theory, Lyapunov functions are addressed to prove that the proposed adaptive master-slave large-scale system can be guaranteed to be asymptotic synchronization with the improper actuator and faulty transmitted signals. Finally, a multiple vehicle large-scale system is used to verify the efficiency of the method.