Factors for Postoperative Gallstone Occurrence in Patients with Gastric Cancer: a Meta-analysis

Chen, Xiang-Jun,Li, Nian,Huang, Ying-De,Ren, Shuang,Liu, Fang,Chen, Lian,Wang, Yong,Chen, Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Objective: To evaluate risk factors for gallstones after gastrectomy. Methods: To identify documents published from 1990 to 2011 the Pubmed, Cochrane Library, Springer Link, CBM and WanFang databases were searched and a meta-analysis was performed with RevMan 5.2 software for odds ratios and 95%CIs. Results: Fifteen studies were selected for the meta-analysis. The pooled ORs [95%CIs] were 0.56 [0.43, 0.73], (P<0.0001) for digestive tract reconstruction, 0.80 [0.54, 1.17], (P=0.25) for pylorus preservation, 0.33[0.15, 0.75], (P=0.008) for resection scope of stomach, 0.33 [0.15, 0.75], (P=0.008) for lymphadenectomy, and 0.13 [0.05, 0.33], (P<0.0001) for vagotomy. Conclusions: Digestive tract physical reconstruction and vagus nerve preservation can reduce the morbidity of gallstones after gastrectomy. Total gastrectomy can add to the morbidity of galltones as does increasing the degree of lymph node dissection. There was no significant difference in gallstones with or without pylorus preservation.

Study of the Band-gap Structure of a 1D-photonic Crystal by Using Different Numerical Approaches

Liang-Yao Chen,Jian-Bo Chen,Yue-Rui Chen,Yan Shen,Wei-Xi Zhou,Jiu-Chun Ren,Yu-Xiang Zheng 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4

Comparative studies between the transfer matrices method (TMM) and plane wave method (PWM) approaches have been performed on 1D photonics crystal under different conditions to show the differences between these two kinds of calculations. TMM is suitable for the design of 1D photonic crystal device with high precision and is in good agreement with experimental results, but is not suitable for the 2D and 3D photonic structures which are limited by the complicated boundary conditions at micro interfaces. The result based on the PWM approach to deal approximately with the photonic structure in approximation has not yet been strictly verified by experiment, not even for 1D photonic crystal structures. More efforts will be required to explore its validation under all physical conditions to enhance its application.

The New Ecosystem of Cross-border E-Commerce among Korea, China and Japan Based on Blockchain

Xiang-Dong Shen,Xi Chen,Ran Ji,Ren-Hong Wu 한국무역학회 2020 Journal of Korea trade Vol.24 No.5

Purpose - The purpose of the study is to propose a theoretical framework of cross-border e-commerce ecosystems based on blockchain technology. The ecosystem includes five systems, namely, crossborder supply chain intelligent system, cross-border logistics system, cross-border payment system, cross-border product quality traceability system and cross-border customs supervision system. Design/methodology - This study firstly derived the main improvement factors for the new ecosystem based on blockchain through prior research and expert interviews on cross-border e-commerce. Then explored the use of virtue of decentralization, anti-counterfeiting traceability, consensus mechanism, smart contract and other means of the core technology of blockchain to overcome the bottleneck of cross-border e-commerce development among Korea, China, and Japan. Finally, proposed valuable implications in both theoretical and practical perspectives. Findings - As a result, we combined with the problems existing in cross-border e-commerce among Korea, China and Japan, this paper proposes a solution based on blockchain. On this basis, it constructs a cross-border e-commerce ecosystem among these three countries, including five systems. In addition, we discuss the main problems existing in the current blockchain, such as low transaction concurrency, security loopholes, and inconsistent standards, the corresponding countermeasures are proposed from the technical level, security level and industry standards. Originality/value - This study is the first to apply the blockchain technology to solve the cross-border e-commerce problems in Korea, China and Japan, which is of pioneering significance in both literature and practice. Block chain technology is in the ascendency. This study provides technical solutions for promoting the development of cross-border e-commerce import and export trade between Korea, China and Japan.

The transcription factor PjERF1 enhances the biosynthesis of triterpenoid saponins in Panax japonicus

Chen Qin,Yu Yilin,Zhang Xiang,Zhao Ren,Zhang Jinyu,Liu Diqiu,Cui Xiuming,Ge Feng 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.5

The ERF-type transcription factors (TFs) play vital roles in plant secondary metabolism. ERF TFs simultaneously regulate the expression levels of key enzyme genes involved in the biosynthesis of secondary metabolites due to its “multi-point control” function. In this study, one gene of ERF TFs from Panax japonicus (PjERF1) was cloned. The open reading frame of PjERF1 was 801 bp and encoded 266 amino acids. Phylogenetic analysis showed that PjERF1 belonged to ERF subfamily with a typical conserved domain. Subcellular localization found that PjERF1 protein might be located in eukaryotic cell nucleus. Yeast one-hybrid assay demonstrated that PjERF1 could bind to the promoters of PjβAS, PjCAS, and PjSE specifically and regulate the expression levels of such key enzyme genes involved in the triterpene saponins biosynthesis. Therefore, in the PjERF1 overexpression cell lines, the expression levels of some key enzyme genes involved in the triterpenoid saponins biosynthesis were significantly increased compared with those in non-transgenic cell line. As a result of it, the biosynthesis of chikusetsusaponin IV and IVa, and other ginsenosides (Rd, Rb1, Re, and R0) were also promoted in the PjERF1 over- expression cell lines. This study indicated that PjERF1 could regulate the biosynthesis of saponins in P. japonicus through controlling the expression levels of key enzyme genes related to the biosynthesis of triterpenoid saponins.

HE4 as a Serum Biomarker for ROMA Prediction and Prognosis of Epithelial Ovarian Cancer

Chen, Wen-Ting,Gao, Xiang,Han, Xiao-Dian,Zheng, Hui,Guo, Lin,Lu, Ren-Quan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Background and Purpose: Human epididymis protein 4 (HE4) has been suggested to be a novel biomarker of epithelial ovarian cancer (EOC). The present study aimed to evaluate and compare HE4 with the commonly used marker, carbohydrate antigen 125 (CA125), in prediction and therapy-monitoring of EOC. Patients and Methods: Serum HE4 concentrations from 123 ovarian cancer patients and 174 controls were measured by Roche electrochemiluminescent immunoassay (ECLIA). Risk of ovarian malignancy algorithm (ROMA) values were calculated and assessed. In addition, the prospects of HE4 detection for therapy-monitoring were evaluated in EOC patients. Results: The ROMA score could classify patients into high- and low-risk groups with malignancy. Indeed, lower serum HE4 was significantly associated with successful surgical therapy. Specifically, 38 patients with EOC exhibited a greater decline of HE4 compared with CA125. In contrast, elevation of HE4 better predicted recurrence (of 46, 11 patients developed recurrence, and with it increased HE4 serum concentrations) and a poor prognosis than CA125. Conclusions: This study suggests that serum HE4 levels are closely associated with outcome of surgical therapy and disease prognosis in Chinese EOC patients.

Quadrilateral RAC filled FRP tubes: Compressive behavior, design and finite element models

Ming-Xiang Xiong,Xuchi Chen,Fengming Ren 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.48 No.5

The need for carbon neutrality in the world strives the construction industry to reduce the use of construction materials. Aiming to this, recycled aggregate concrete (RAC) could be used as it reduces the carbon dioxide emissions. Currently, RAC is mainly used in non-structural members of civil constructions, seldom used in structural members. To broaden its structural use, a new type of composite column, i.e., the square and rectangular RAC filled FRP tubes (CFFTs), has been concerned in this study. The investigation on their axial compressive behavior through physical test and numerical analysis demonstrated that the load-carrying capacity of such column is reduced with the increase of replacement ratio of recycled aggregate and aspect ratio of section but can be improved by the increase of FRP confining stiffness and corner radius, said capacity can be equivalent to their steel reinforced concrete counterparts. At failure, the hoop strain at corner of tube is unexpectedly smaller than that at flat side of the tube although the FRP tube ruptured at its corner first, revealing a premature failure. Besides, a design-oriented stress-strain model of concrete and an analysis-oriented finite element model are proposed to predict the load-strain response of square and rectangular CFFT columns, which facilitates the engineering use of RAC in loadcarrying structural members.

New multifunction materials with both electrorheological performance and luminescence property

Ming-Xing Chen,Yan-Li Shang,Yun-Ling Jia,Xiang-Yu Dong,Jing Ren,Jun-Ran Li 한국유변학회 2017 Korea-Australia rheology journal Vol.29 No.1

Novel multifunctional materials, the composites AlOOH-NaYFTb5 and AlOOH-NaYFTb10, containing AlO(OH) and β-NaYF4:5%Tb3+, have been synthesized via a facile hydrothermal route and a simple grinding method. The boehmite [AlO(OH)], yttrium nitrate [Y(NO3)3·6H2O], terbium nitrate, [Tb(NO3)3·6H2O], sodium citrate (Na3C6H5O7·2H2O) and sodium fluoride (NaF) were used as starting materials. The composition, electrorheological (ER) performance, and luminescence property of the functional materials were studied. Our results show that the composites not only have good electrorheological (ER) performance, but also have good optics property. The relative shear stress τr (τr = τE/τ0, τE and τ0 are the shear stresses at the electric field strength E = 4 and 0 kV/mm, respectively) values of the suspension (25 wt.%) of AlOOHNaYFTb5 material in silicone oil are all larger than 50 in a shear rate ranging from 0.06 to 26 s−1, the τr value reaches 1333 at a shear rate of 0.06 s−1. The material with such high ER activity and favorable luminescence performance is advantageous in its application as a multifunctional material.

Meta-analysis of Outcomes Compared between Robotic and Laparoscopic Gastrectomy for Gastric Cancer

Liao, Gui-Xiang,Xie, Guo-Zhu,Li, Rong,Zhao, Zhi-Hong,Sun, Quan-Quan,Du, Sha-Sha,Ren, Chen,Li, Guo-Xing,Deng, Hai-Jun,Yuan, Ya-Wei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

This meta-analysis was performed to evaluate and compare the outcomes of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for treating gastric cancer. A systematic literature search was carried out using the PubMed database, Web of Knowledge, and the Cochrane Library database to obtain comparative studies assessing the safety and efficiency between RG and LG in May, 2013. Data of interest were analyzed by using of Review Manager version 5.2 software (Cochrane Collaboration). A fixed effects model or random effects model was applied according to heterogeneity. Seven papers reporting results that compared robotic gastrectomy with laparoscopic gastrectomy for gastric cancer were selected for this meta-analysis. Our metaanalysis included 2,235 patients with gastric cancer, of which 1,473 had undergone laparoscopic gastrectomy, and 762 had received robotic gastrectomy. Compared with laparoscopic gastrectomy, robotic gastrectomy was associated with longer operative time but less blood loss. There were no significant difference in terms of hospital stay, total postoperative complication rate, proximal margin, distal margin, numbers of harvested lymph nodes and mortality rate between robotic gastrectomy and laparoscopic gastrectomy. Our meta-analysis showed that robotic gastrectomy is a safe technique for treating gastric cancer that compares favorably with laparoscopic gastrectomy in short term outcomes. However, the long term outcomes between the two techniques need to be further examined.

Hydrothermal synthesis of cobalt germanium oxide supported with carbon-based graphitic carbon nitride for electrochemical determination of ornidazole

Jaysiva Ganesamurthi,Xiang-Ren Chen,Ruey-Shin Juang,Siang-Yu Wei,Da-Yuan Lin 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-

In recent decades, nitroimidazole derivatives have played an effectual role against bacterial and protozoaninfections that can be used as anti-cancer and antibiotic drugs. Ornidazole (ORD) consists of a major5-imidazole nucleus which complements to first nitro groups, ORD invades into lipid tissue and othernitroimidazole derivatives. The periodic intake of ORD orally causes side effects of headache, nausea,vomiting, and breathing difficulties such effects need potential monitoring and develop essential electrochemicalsensing toward ORD. In this study, we developed a ternary cobalt germanium oxide (Co2GeO4)nanoparticle prepared by a facile hydrothermal method and followed by calcination. The carbon-basedgraphitic carbon nitride (GCN, g-C3N4) nanosheets were therefore supported for electrochemical sensingapplications in order to improve the features like the catalytic activity, electrical conductivity, and activesurface area of Co2GeO4 composites. The structural, chemical composition, and morphological propertiesof samples were characterized. Subsequently, the fabrication of cobalt germanium oxide with graphiticcarbon nitride (Co2GeO4/GCN) was modified over a screen-printed carbon electrode (SPCE) towards electrochemicaldetection of ORD. Electrochemical measurements were recorded by cyclic voltammetry (CV)and differential pulse voltammetry (DPV) for the determination of ORD. The Co2GeO4/GCN nanocompositeexhibits a wide linear range response of 0.049–94.9 lM in DPV with a nanomolar limit of detection of7.2 nM of ORD and a high sensitivity of 2.66 lA lM1 cm2. An interference study was carried out for theCo2GeO4/GCN nanocomposite in the existence of hazardous metals, biological compounds, and similardrugs for examining the selectivity of the sensor. The proposed Co2GeO4/GCN nanocomposite revealssuperior sensing selectivity towards ORD; hence, repeatability, reproducibility, and storage stability wererecorded in their RSD and found to be less than 0.4%, adding to this practical feasibility of the sensor analyzedby real samples of blood serum & human urine with exceptional recovery percentages.

PDCD4 as a Predictor of Sensitivity to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients

Dou, Xue,Wang, Ren-Ben,Meng, Xiang-Jiao,Yan, Hong-Jiang,Jiang, Shu-Mei,Zhu, Kun-Li,Xu, Xiao-Qing,Chen, Dong,Song, Xian-Rang,Mu, Dian-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Objective: The purpose of this study was to examine the role of programmed cell death 4 (PDCD4) expression in predicting tumor response to neoadjuvant chemoradiotherapy and outcomes for patients with locally advanced rectal cancer. Methods: Clinicopathological factors and expression of PDCD4 were evaluated in 92 patients with LARC treated with nCRT. After the completion of therapy, 4 cases achieved clinical complete response (cCR), and thus the remaining 88 patients underwent a standardized total mesorectal excision procedure. There were 38 patients (41.3%) with a good response (TRG 3-4) and 54 (58.7%) with a poor one (TRG 0-2). Results: Immunohistochemical staining analyses showed that patients with high expression of PDCD4 were more sensitive to nCRT than those with low PDCD4 expression (P=0.02). High PDCD4 expression before nCRT and good response (TRG3-4) were significantly associated with improved 5-year disease-free survival and 5-year overall survival (P<0.05). Multivariate analysis demonstrated that the pretreatment PDCD4 expression was an independent prognostic factor. Conclusion: Our study demonstrated that high expression of PDCD4 protein is a useful predictive factor for good tumor response to nCRT and good outcomes in patients with LARC.