Presurgical Naso-Alveolar Molding Appliance for Unilateral Cleft Lip and Palate

Baek, Seung-Hak,Yang, Won-Sik,Kim, Sukwha 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.6

본 연구의 목적은 1)편측성 순구개열 신생아 환자에 대한 술전 비치조 정형장치(PNAM)치료를 소개하고 2) 이 장치의 치조골 정형 효과를 평가하는 것이다. 서울대학교 병원 교정과에 내원하여 PNAM장치를 사용하여 치료받은 4명의 편측성 순구개열 호나자(남자 3명, 여자 1명, 평균 초진연령: 23.2일)을 대상으로 하였으며, 치조골에서 대분절과 소분절 파열부간의 평균거리는 8.27mm였고 치조골 정형치료의 평균기간은 9.7주였다. 초진시(Ti)와 성공적인 치조골 정형술이 이루어진 시기(T2)에 이들 환자의 인상을 채득하여 모형을 제작한 후, 사진촬영과 digital caliper를 사용하여 7개의 길이 항목과 5개의 각도항목을 계측하였다. SPSS win. ver 7.5프로그램을 사용하여 통계처리 하였고, 평균치의 차이를 비교하기 위하여 paired t-test를 사용하였다. 1. 신생아 치조골 후방부는 치조골 정형술을 시행하는 동안 안정된 구조물이었다. 2. 치조골 정형술에 의하여 대분절의 전방 성장이 억제되었다. 3. 치조골 정형술에 의한 파열부의 패쇄는 주로 대분절 전방부의 내측과 후방 굴곡 및 소분절 전체의 외측 굴곡에 의한 것이었다. The goals of this study were to present presurgical naso-alveolar molding(PNAM) appliance in unilaterla cleft lip and palate treatment and to evaluate the effects of PNAM appliance on alveolar molding. Samples were consisted of 4 unilateral cleft lip and palate infants(3 males and 1 female, mean age=23.2 days after birth) who were treated with PNAM appliances in Department of Orthodontics, Seoul National University Dental Hospital. Average alveolar cleft gap between the greater and lesser segment was 8.27 mm and average duration of alveolar molding treatment was 9.7 weeks. These patients' models were obtained at initial visit(T1) and after successful alveolar molding(T2). Seven linear and five angular variables were measured by using photometry and digital caliper. All statistical analyses were performed by SPSS win ver. 7.5 program. Paired t-test was used to compare the mean values. 1. The posterior part of alveolar segments are the stable structures during alveolar molding treatment period in infants. 2. Forward growth of th greater segment may be hindered by the action of alveolar molding. 3. The closure of cleft gap during alveolar molding were usually due to inward and backward bending of the anterior part of the greater segment and outward bending of the whole lesser segment.

신경망분석을 이용한 축구경기 승,패 예측모형 개발 -2006독일월드컵 대회를 중심으로-

김주학 ( Joo Hak Kim ),노갑택 ( Gap Taik Ro ),박종성 ( Jong Sung Park ),이원희 ( Won Hi Lee ) 한국스포츠정책과학원(구 한국스포츠개발원) 2007 체육과학연구 Vol.18 No.4

본 연구는 축구 경기 기록자료를 활용하여 축구경기의 승·패를 예측할 수 있는 모형을 개발하는 데 있다. 활용된 경기기록 자료는 2006년 독일 월드컵대회에 나타난 축구경기 전체 64경기의 FIFA TSG공식자료와 M대학교 경기분석 프로그램을 활용하여 산출된 경기기록 자료를 사용하였다. 연구기법으로는 최근에 예측연구에 많이 활용되고 있는 신경망 분석을 이용하여 예측율을 확인 하였으며, 예측율은 2개의 예측모형으로 분류하여 결과를 산출하였다. 구체적인 내용 및 방법은 다음과 같다. 2006년 독일월드컵에 나타난 기록 관련 요인 중 경기 내적요인을 중심으로 축구 경기의 승·패와 관련한 요인을 탐색하고 2006년 독일월드컵 전 경기에 대한 비디오녹화를 실시하였으며, 녹화된 비디오를 통하여 기록요인에 대하여 실시간 축구 경기분석 프로그램을 활용, 승·패와 관련한 기록요인을 점수화하였다. 점수화된 기록요인은 점유율, 성공률 관련 등 여러 가지 요인이 있었으나 실제 경기에서 예측을 할 수 있는 요인을 전문가와 회의를 통하여 선정하고 선정된 요인을 바탕으로 신경망 분석방법을 이용하여 축구경기 승·패 예측 모형을 개발하여 예측율을 확인하였다. 본 연구의 결과는 다음과 같다. 첫째, 전문가회의를 통하여 기록화 할 수 있는 기록자료 요인을 중심으로 2006년 독일월드컵 전체 경기에 대하여 축구 경기분석 프로그램을 통하여 점수화하여 실제 다양한 요인이 내재된 경기에 대하여서도 내용분류를 통하여 점수화할 수 있음을 확인하였다. 둘째, 점수화된 경기 내적요인을 중심으로 신경망분석 방법을 통하여 축구경기에 대하여서도 승·패를 예측할 수 있음을 확인하였으며 타 종목에 대하여서도 실현 가능함을 확인할 수 있었다. 셋째, 축구경기의 승패에 대하여 87.5%의 예측율을 보임으로써 축구경기의 요인에 대한 중요도를 평가할 수 있는 연구의 기초를 확립하였다고 판단된다. This study was on purpose to investigate the various factors of soccer games into inner factors and classify performance factors objectively and scientifically using a soccer game analysis program and develop a model which can predict the result of the soccer games using the Neural NetWork Analysis that stands on the game graded record. The game recorded data was collected from the FIFA TSG official record and the data which was gained using a game analysis program. It has searched the factors related the game results which were focused on the game inner factors of the related factors in 2006 World cup games and recorded the whole games of 2006 World cup games, graded the recording factors related the win/lose using the video and the real time game analysis program with numbers. The graded recording factors with numbers were several; ball possession, completion, and so on. However, through the meeting with Neural NetWork Analysis, professionals prediction related factors which can predict in the real games were selected. And a soccer game win/lose prediction model was developed using the selected factors and Neural NetWork Analysis. It also was compared with the preceding researches in documents record studies. Followings are main results of this study; First, It was confirmed that it is available to grade the real factors in the games which include various factors through the professionals` meetings which implemented the analysis the 2006 Worldcup games and it was focused on the recording factors. Second, the graded recording inner-factors make it possible to predict the soccer game results using the Neural NetWork Analysis method. It was verified that it can be effective in other sports also. Third, the rate of predicting the soccer games` results was 87.5%. It is possible to understand this study contributes on the basis of the importancy of soccer game factors.

배구 서브리시브에 따른 팀 간 공격 차이 분석

김종원 ( Jong Won Kim ),김주학 ( Joo Hak Kim ),김진환 ( Jin Hwan Kim ),홍성진 ( Seong Jin Hong ) 한국스포츠정책과학원(구 한국스포츠개발원) 2011 체육과학연구 Vol.22 No.3

이 연구는 국내 남자프로배구경기에서 나타난 서브리시브에 따른 팀간 공격 차이를 서브리시브의 유효성, 세터/비세터에 의한 세트, 세터의 위치, 공격형태, 공격결과를 기반으로 어떠한 차이가 있는지를 알아보기 위하여 NH농협 2009~2010 V리그 남자프로배구경기 126경기를 대상으로 하였다. 분석된 요인들을 기반으로 팀간 공격형태별 빈도, 대전팀간 교차분석, 공격형태별 성공 비율 차이를 분석하여 다음과 같이 나타났다. 첫째, 요인에 따른 공격형태별 빈도를 분석한 결과, 서브리시브가 성공하였을 경우 7개팀 중 5개팀이 속공공격, 실패하였을 경우 7개팀 모두가 오픈공격의 빈도가 높게 나타났다. 둘째, 요인에 따른 대전팀 교차분석의 차이를 검증해 본 결과 차이가 나타났다. 시즌 1위팀인 S팀은 7위팀인 A팀보다 서브리시브 성공률에서 10%이상의 차이가 나타났으며, 서브리시브의 성공·실패와 상관없이 7개팀 모두 96%이상의 세트가 세터에 의해 이루어지는 것으로 나타났다. 또한, 공격결과 성공률 평균에서는 상위팀인 S팀·H팀(56.9%), 중위팀인 D팀·L팀(54.7%), 하위팀인 W팀·K팀·A팀(47.7%)로 나타나 상위팀일수록 더 높은 공격결과 성공률 평균이 나타났다. 셋째, 공격형태별 성공 비율 차이를 분석한 결과, 이동공격을 제외한 모든 공격형태에서 차이가 나타났다. 오픈공격에서는 S팀이 D팀은 제외한 모든 팀보다 높은 오픈공격 성공 비율의 차이가 나타났으며, A팀은 W팀을 제외한 모든 팀에게 높은 오픈공격 성공 비율의 차이를 나타내주는 특징을 보였다. 시간차공격에서는 K팀이 A팀을 제외한 모든 팀에게 높은 시간차공격 성공 비율의 차이를 나타내주었으며, 속공공격에서는 H팀이 D팀을 제외한 모든 팀에게 높은 속공공격 성공 비율의 차이가 나타났다. 후위공격에서는 하위팀인 W팀·K팀·A팀에서 상위팀들에게 높은 후위공격의 성공 비율의 차이를 나타내주는 특징을 보였다. 퀵오픈공격에서는 A팀이 K팀은 제외한 모든 팀에게 높은 퀵오픈공격 성공 비율을 나타내주는 특징을 보였다. 서브리시브에 따른 팀 간 공격에서 서브리시브의 유효성, 세터/비세터에 의한 세트, 세터의 위치, 공격형태, 공격결과에 따라 팀 간 차이가 나타났다. 안정된 서브리시브와 세트는 여러 공격형태와 높은 공격성공률과의 관계가 매우 높다고 볼 수 있다. 대부분의 기록에서 승리한 팀이 패배한 팀보다, 시즌 순위 기록으로 상위팀이 하위팀보다 우위를 나타내 여러 요인들의 안정 및 높은 성공률을 위하여 꾸준한 연습과 대전팀의 경기기록에 대한 연구가 필요하다. The study was to compare the differences of attacking patterns related to serve receives basing on effectiveness of serve receives, setter/non-setter, location of setter, type of attacks and outcomes of attacks. The subjects were 126 games in 2009~2010 Korean NH Nonghyub V-league men`s championships. The analysed factors were considered on frequencies of type of attacks by each team, cross comparisons between teams played and a ratio of successful outcome by the type of attacks. The results were found as following belows; Firstly, in the comparisons of frequencies on the type of attacks, 5 teams among 7 teams shown greater frequencies on counter-attacks while the teams were winning. Secondly, there were significant differences of types of attacks between teams. The championships` winner, team S was greater than other teams about 10 % of successful serve-receives and 96% of sets were done by setter without the relationships of successful or unsuccessful serve-receives. Also, the successful percentage of attacking outcomes were ordered by ranks such as superior team S and H (56.9%), mid-ranks team D and L (54.7%) and inferior team W, K and A (47.7%). Thirdly, in the comparisons of successful ratio of type of attacks, there were significant differences between the type of attacks except moving-attacks. In the open-attacks, the ratio by team S was greater than team D. In addition, there was significant difference on the ratio by team A excepted the comparing with team W. In the time difference attacks, the ratio by team K was different comparing to other teams excepting team A. In the counter-attacks, team H were greater ratio excepting to team D. In the backward-attacks, the inferior teams (W, K and A) made greater successful ratio of attacks against the superior teams. In the quick-attacks, there was grater ratio by team A against others excepted to team K. There were differences of the effectiveness of serve-receives, sets by setter/ non-setter, location of setter, type of attacks and outcome of attacks depending on the teams. The stable serve-receives and sets were highly relevant to the various types of attacks and greater ratio of successful attacks. The continuous practice and study on oppositional data are required in order to enhance their performances because the winning and superior teams were stable ratio of successful attacks rather than the losing and inferior teams.

인공지능 모델에 따른 한국 프로야구의 승패 예측 분석에 관한 연구

김태훈 ( Tae-hun Kim ),임성원 ( Seong-won Lim ),고진광 ( Jin-gwang Koh ),이재학 ( Jae-hak Lee ) (사)한국빅데이터학회 2020 한국빅데이터학회 학회지 Vol.5 No.2

본 연구에서는 인공지능 모델에 따른 한국 프로야구의 승패 예측 분석에 관한 연구를 했다. 승리할 팀과 해당 팀의 최종 리그 순위를 예측했고, 사용자의 편의를 위해 웹사이트도 구축했다. 각 1·3·5이닝 별로 가장 정확도가 높으면서도 오차가 적은 모델을 최적 모델로 선정해 승·패 결과를 예측했고, 이를 토대로 순위표를 작성했다. 결과표는 2020년 개막인 5월 5일부터 8월 30일까지의 예측 결과를 바탕으로 작성했다. 기아타이거즈가 아닌 다른 구단끼리의 경기는 실제 결과를 사용했다. 머신러닝 모델은 KNN과 AdaBoost가 최적 모델로 선정되었으며, 실제 순위와 비교해 본 결과, 경기가 진행될수록, 예측 결과의 순위 오차가 점점 작아지는 것을 확인했다. 딥러닝 모델은 89%의 정확도를 기록했고, 머신러닝 모델과 마찬가지로 경기를 진행할수록 예측 결과 순위 오차가 작아지는 것을 확인했다. 실험 결과는 한국 프로야구 승·패 결과 예측뿐 아니라 다양한 분야에서 사용할 수 있을 것으로 사료된다. 방송국에서 야구 경기를 중계하는 중 이닝별로 인공지능 알고리즘이 예상한 승·패 여부를 중계화면에 띄울 수 있다. 시청자들에게 새로운 흥미를 일으킬 수 있을 것이고, 나아가 구단의 감독들이 이닝마다 데이터를 분석해 경기 중 유동적으로 승리하기 위한 전략을 세울 수 있을 것으로 기대된다. In this study, we conducted a study on the win-loss predicton analysis of korean professional baseball by artificial intelligence models. Based on the model, we predicted the winner as well as each team’s final rank in the league. Additionally, we developed a website for viewers’ understanding. In each game’s first, third, and fifth inning, we analyze to select the best model that performs the highest accuracy and minimizes errors. Based on the result, we generate the rankings. We used the predicted data started from May 5, the season’s opening day, to August 30, 2020 to generate the rankings. In the games which Kia Tigers did not play, however, we used actual games’ results in the data. KNN and AdaBoost selected the most optimized machine learning model. As a result, we observe a decreasing trend of the predicted results’ ranking error as the season progresses. The deep learning model recorded 89% of the model accuracy. It provides the same result of decreasing ranking error trends of the predicted results that we observe in the machine learning model. We estimate that this study’s result applies to future KBO predictions as well as other fields. We expect broadcasting enhancements by posting the predicted winning percentage per inning which is generated by AI algorism. We expect this will bring new interest to the KBO fans. Furthermore, the prediction generated at each inning would provide insights to teams so that they can analyze data and come up with successful strategies.

[P311] Metastatic cutaneous duodenal gastrointestinal stromal tumor: a visible clue to multiple metastases

( Hak Tae Kim ),( Young Jae Kim ),( Woo Jin Lee ),( Chong Hyun Won ),( Sung Eun Chang ),( Jee Ho Choi ),( Mi Woo Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

We report a case of a 69-year-old man with metastatic cutaneous duodenal gastrointestinal stromal tumor, which led to find multiple metastases on orbital muscle and scalp. The patient presented with a rapidly growing chest nodule with mild tenderness. He underwent surgical resection for duodenal gastrointestinal stromal tumor and had been treated with imatinib for three years. Histopathological examination of the chest nodule was consistent with gastrointestinal stromal tumor. A brain magnetic resonance imaging of follow work-up revealed multiple metastases at the left superior rectus muscle and occipital scalp. Under the diagnosis with imatinib-resistant duodenal gastrointestinal stromal tumors, a second-line therapy with sunitinib was tried. After six weeks, all skin lesions were completely improved and other metastatic cancers showed a response of stable disease to sunitinib therapy. This is the first reported case of metastatic cutaneous duodenal gastrointestinal stromal tumor followed by multiple metastases. Cutaneous metastases from a gastrointestinal stromal tumor have been considered to be a late progressive manifestation suggested being an indicative of multiple metastases. This report emphasizes the importance of a full-skin examination in patients with a medical history of gastrointestinal stromal tumor which leads to find multiple metastases possibly treated with sunitinib.

[P310] Pancreatic extraskeletal osteosarcoma metastasizing to the scalp

( Hak Tae Kim ),( Young Jae Kim ),( Chong Hyun Won ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ),( Woo Jin Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Extraskeletal osteosarcoma (ESOS) is a rare mesenchymal soft tissue neoplasm which accounts for approximately 1% of all soft tissue sarcomas. More than 70% of this malignant tumor progresses local recurrence and metastasis. It is commonly metastasized to the lungs, lymph nodes, bone, and skin with poor survival outcome. Cutaneous metastasis is an exceedingly rare and known to be a flag sign of widespread metastases. We present a 57-year-old woman presented with a rapidly growing protruding mass on the scalp which is finally diagnosed with metastatic ESOS from primary pancreatic ESOS. To our knowledge, there has been no reported case of pancreatic extraskeletal osteosarcoma metastasizing to the scalp.

#VALUE!

( Hak-jun Kim ),( Kihyuk Shin ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Gun-wook Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Hoon-soo Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Partial regression of primary cutaneous melanoma is a relatively common finding, and it occurs in 10% to 35% of cases regardless of Breslow thickness. Melanoma is known to demonstrates regression 6 times more often than other malignant neoplasm. By contrast, complete regression of primary cutaneous malignant melanoma is even more rare with only approximately 40 reported cases in the English literature. This is a rare case of completely regressed primary cutaneous melanoma with nodal metastasis. We report a 43-year-old man with painful subcutaneous mass was developed on the left inguinal area from 6 months ago. Fine needle biopsy was performed, a metastatic malignant melanoma was diagnosed. The patient was referred to the dermatology to find the primary skin lesion of metastatic malignant melanoma. A suspected skin lesion was founded in the left lower back. Pigmented solitary plaque developed for few years, but the lesion size has been decreasing from 6 months ago. Histopathologic findings shows epidermal hyperplasia in the epidermis, generalized fibrosis, enlarged blood vessels, patchy band-like inflammatory cell infiltration, and some of melanophages were observed in the dermis. However, no evidence of melanoma was founded in serial sections. This is the first report of a patient with completely regressed primary cutaneous malignant melanoma in Korean dermatologic literature.

Alteration of DNA Methylation in Oct-4 Gene in Mouse Preimplantation Embryos by the Interference RNA

Kim, Jong-Mu,Ko, Yeoung-Gyu,Seong, Hwan-Hoo,Chung, Hak-Jae,Chang, Won-Kyong,Kim, Nam-Hyung The Korean Society of Animal Reproduction 2007 Reproductive & developmental biology Vol.31 No.1

During early embryo development, Oct-4 is an important transcription factor for the early differentiation the present study was first examined methylation status in distal enhancer and promoter region of Oct-4 during mouse pre-implantation embryo development. In oocyte and sperm, high methylation was observed in both distal and proximal of promoter in Oct-4. Following fertilization relatively high methylation level remained until 8-cell stage embryos, but decreased at the morula and blastocyst stage. Specific gene knock down of Oct-4 by siRNA injection into zygote induced higher methylation rates of both distal and proximal region of promoter of Oct-4. These results suggest a functional link between the DNA methylation status of distal and promoter resign in the Oct-4 gene and the gene sequence-specific transcriptional silencing by exogenous siRNA injection during mouse preimplantation embryos.

Nevoid basal cell carcinoma syndrome associated with rare PCTH1 gene mutation

( Hak-jun Kim ),( Kihyuk Shin ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Byung-soo Kim ),( Moon-bum Kim ),( Hyun-chang Ko ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Nevoid basal cell carcinoma syndrome (NBCCS) is rare multi-systemic disorder characterized by early onset of multiple basal cell carcinoma and odontogenic keratinocysts. In addition, palmar or plantar pits, ectopic calcification of the falx cerebri, skeletal abnormalities, and increased incidence of variety of tumors were also reported in NBCCS. NBCCS is a congenital disorder caused by PTCH1 gene mutation. To date, over 100 germline mutation in PTCH1 associated with NBCCS have been reported. A 9-year-old boy was referred with multiple odontogenic keratinocysts. He had past history of macrocephaly and developmental delay. Physical examination revealed several brownish elevated papules on the face. Histopathologic findings were consistent with superficial type of basal cell carcinoma. Calcification of the falx cerebri was founded through brain CT. Furthermore, genetic analysis founded a missense mutation that shows the nucleotide substitution c.317T>G, resulting in p.Leu106Arg in PTCH1 gene. The same mutation also founded in patient’s father. Through these characteristic clinical symptoms, radiologic findings and genetic analysis, patient was finally diagnosed as NBCCS.

Effect of different culture type and stocking density on growth and survival rates of the hard shelled mussel Mytilus coruscus in Gunsan coastal water

Hak Bin Lee,Jeong Kyu Oh,Mi Ryoung Oh,Hyun Jeong Jo,Dae Won Jeong,Hyung Seop Kim,Kwang-Sik Choi,Chul Won Kim 한국수산과학회 양식분과 2016 한국수산과학회 양식분과 학술대회 Vol.2016 No.10