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Experimental study of beam-column connections with web opening in a low-rise steel frame
Wang, Xiuli,Yin, Zhanzhong,Li, Qingfu,Shen, Shizhao Techno-Press 2007 Structural Engineering and Mechanics, An Int'l Jou Vol.26 No.3
Steel frame structures have been widely used in multi-storey and high-rise buildings and the connections in these structures are critical. In the Northridge and Kobe Earthquake, beam-column connections suffered damage due to brittle fracture. According to seismic design codes, ductility of the beam to column connection is also necessary. A study on the behavior of a beam to column connection with the aim of improving ductility as well as preventing brittle failure was carried out. In order to control the position of a plastic hinge on the beam, a connection with a hole in the beam web was developed. Five specimens with different parameters under cyclic load were assessed. The results are presented in terms of the stress distribution of the beam, hysteretic behavior, and ultimate capacity. Furthermore, the finite element method was also used to analyze the model, and the results were compared with those obtained from the experiment. It is shown from the analysis and experimental results that this type of connection is effective in terms of improving ductility for a beam to column connection in low-rise buildings.
Wang Xiuli,Song Yunquan,Zhang Shuxia 한국통계학회 2020 Journal of the Korean Statistical Society Vol.49 No.3
In this paper, we study the weighted quantile average estimation technique for the parameter in additive partially linear models with missing covariates, which is proved to be an efficient method. The proposed method is based on optimally combining information over different quantiles via multiple quantile regression. We establish asymptotic normality of the weighted quantile average estimators when the selection probability is known, estimated using the non-parametrical method and parametrical method, respectively. Moreover, we compute optimal weights by minimizing asymptotic variance and then obtain the corresponding optimal weighted quantile average estimators. To examine the finite performance of our proposed method, we use the numerical simulations and apply to model time sober for the patients from a rehabilitation center. Simulation results and data analysis further verify that the proposed method is an efficient and safe alternative to both theWCQRmethod andWLSmethod.
Xiuli Wang,Yonggang Lu,Rongsheng Zhu,Qiang Fu,Haoqian Yu,Yiming Chen 한국원자력학회 2019 Nuclear Engineering and Technology Vol.51 No.7
The AP1000 reactor coolant pump is a vertical shielded-mixed flow pump, is the most important coolant power supply and energy exchange equipment in nuclear reactor primary circuit system, whose steady-state and transient performance affect the safety of the whole nuclear island. Moreover, safety demonstration of reactor coolant pump is the most important step to judge whether it can be practiced, among which software simulation is the first step of theoretical verification. This paper mainly introduces the fluid-solid coupling simulation method applied to reactor coolant pump, studying the feasibility of simulation results based on workbench fluid-solid coupling technology. The study found that: for the unsteady calculations of the pure liquid media, the average head of the reactor coolant pump with bidirectional fluid-solid coupling decreases to a certain extent. And the coupling result is closer to the real experimental value. The large stress and deformation of rotor under different flow conditions are mainly distributed on impeller and idler, and the stress concentration mainly occurs at the junction of front cover plate and blade outlet. Among the factors that affect the dynamic stress change of rotor, the pressure load takes a dominant position.
Protective Effects of Verapamil against H2O2-Induced Apoptosis in Human Lens Epithelial Cells
( Zhuo Wang ),( Dan Wang ),( Yan Li ),( Xiuli Zhang ) 한국응용약물학회 2014 Biomolecules & Therapeutics(구 응용약물학회지) Vol.22 No.6
Verapamil is used in the treatment of hypertension, angina pectoris, and atrial fibrillation. Recently, several studies have demonstrated that verapamil increased the optic nerve head blood flow and improved the retrobulbar circulation. All these show that verapamil is potentially useful for ophthalmic treatment. Thus, the aim of this study is to investigate whether verapamil could protect human lens epithelial cell (HLEC) from oxidative stress induced by H2O2 and the cellular mechanism underlying this protective function. The viability of HLEC was determined by the MTT assay and apoptotic cell death was analyzed by Hoechst 33258 staining. Moreover, Caspase-3 expression was detected by immunocytochemistry and flow cytometry analysis. We also detected Caspase-3 mRNA expression by reverse-transcription-polymerase chain reaction and the GSH content in cell culture. The results showed that oxidative stress produced significant cell apoptotic death and it was reduced by previous treatment with the verapamil. Verapamil was effective in reducing HLEC death mainly through reducing the expression level of apoptosis-related proteins, caspase-3, and increasing glutathione content. Therefore, it was suggested that verapamil was effective in reducing HLEC apoptosis induced by H2O2.
Antiviral effects of Bovine antimicrobial peptide against TGEV in vivo and in vitro
Xiuli Liang,Xiaojun Zhang,Kaiqi Lian,Xiuhua Tian,Mingliang Zhang,Shiqiong Wang,Cheng Chen,Cunxi Nie,Yun Pan,Fangfang Han,Zhanyong Wei,Wen-Ju Zhang 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.5
Background: In suckling piglets, transmissible gastroenteritis virus (TGEV) causes lethal diarrhea accompanied by high infection and mortality rates, leading to considerable economic losses. This study explored methods of preventing or inhibiting their production. Bovine antimicrobial peptide-13 (APB-13) has antibacterial, antiviral, and immune functions. Objectives: This study analyzed the efficacy of APB-13 against TGEV through in vivo and in vitro experiments. Methods: The effects of APB-13 toxicity and virus inhibition rate on swine testicular (ST) cells were detected using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT). The impact of APB-13 on virus replication was examined through the 50% tissue culture infective dose (TCID50). The mRNA and protein levels were investigated by real-time quantitative polymerase chain reaction and western blot (WB). Tissue sections were used to detect intestinal morphological development. Results: The safe and effective concentration range of APB-13 on ST cells ranged from 0 to 62.5 μg/mL, and the highest viral inhibitory rate of APB-13 was 74.1%. The log10TCID50 of 62.5 μg/mL APB-13 was 3.63 lower than that of the virus control. The mRNA and protein expression at 62.5 μg/mL APB-13 was significantly lower than that of the virus control at 24 hpi. Piglets in the APB-13 group showed significantly lower viral shedding than that in the virus control group, and the pathological tissue sections of the jejunum morphology revealed significant differences between the groups. Conclusions: APB-13 exhibited good antiviral effects on TGEV in vivo and in vitro.
Xiuli Han,Yuyuan He,Haohao Zhao,Duo Wang 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.10
Activated carbon could be prepared from residue of rice husk using physical activation with steam as ac-tivating agent. Response surface methodology (RSM) was applied to optimize the effects of processing parameters,and regression analysis was performed on the data obtained. The optimal conditions for adsorption capacity of activatedcarbon from the residue of rice husk were activation temperature of 946 oC, activation time of 31 min and water (18 g)which changed to steam by heating, resulting in 970.06 mg·g−1of iodine adsorption capacity and 31.36% of activatedcarbon yield. The activated carbon prepared under optimum condition was mesoporous with BET surface area of 1,004.296m2·g−1, total pore volume of 0.9388 cm3·g−1and average pore diameter of 2.043 nm. The surface chemical functionalgroups of activated carbon were identified by FT-IR, and its microstructure was examined by scanning electron micro-scopy (SEM). We concluded that the process of physical activation with steam could be an environmentally harmoniousand effective method for preparing activated carbon from residue of desilicated rice husk.
Wang Jizhe,Liu Shao,Qu Xiaoyan,He Xingrong,Zhang Laixiang,Guo Kun,Zhu Xiuli 한국산업안전보건공단 산업안전보건연구원 2023 Safety and health at work Vol.14 No.3
Background: Job performance is known as an essential reflection of nursing quality. Colleague solidarity, positive emotion, and turnover intention play effective roles in a clinical working environment, but their impacts on job performance are unclear. Investigating the association between nurses’ colleague solidarity and job performance may be valuable, both directly and through the mediating roles of positive emotion and turnover intention. Methods: In this cross-sectional study, a total of 324 Chinese nurses were recruited by convenience sampling method from July 2016 to January 2017. Descriptive analysis, Spearman’s correlation analysis, and the structural equation model were applied for analysis by SPSS 26.0 and AMOS 24.0. Results: A total of 49.69% of participants were under 30 years old, and 90.12% of participants were female. Colleague solidarity and positive emotion were positively connected with job performance. The results indicated the mediating effects of positive emotion and turnover intention in this relationship, respectively, as well as the chain mediating effect of positive emotion and turnover intention. Conclusions: In conclusion, dynamic and multiple supportive strategies are needed for nurse managers to ameliorate nursing job performance by improving colleague solidarity and positive emotion and decreasing turnover intention based on the job demand-resource model.
Wang Chen,Ma Yuanyuan,Shao Zhipeng,Huang Xiuli,Fei Jiaxuan 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.10
With the development of power industry, communication security has become an important issue affecting the stability of power system. IEC 62351 standard provides security for substation communication system. However, different transmission protocols may lead to different manufacturers to produce different understanding, manufacturing is not compatible with the device. In order to avoid such a situation, the Finite State Machine (FSM) theory is used to model and analyze the transmission protocol of IEC 62351 standard. In this paper, the FSM model is simulated by the StateFlow tool, and it can be considered that the FSM theory is applicable to the analysis of compliance with IEC 62351 standard.