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CONFORMAL HEMI-SLANT SUBMERSIONS FROM COSYMPLECTIC MANIFOLDS
Vinay Kumar,Rajendra Prasad,Sandeep Kumar Verma Korean Mathematical Society 2023 대한수학회논문집 Vol.38 No.1
The main goal of the paper is the introduction of the notion of conformal hemi-slant submersions from almost contact metric manifolds onto Riemannian manifolds. It is a generalization of conformal anti-invariant submersions, conformal semi-invariant submersions and conformal slant submersions. Our main focus is conformal hemi-slant submersion from cosymplectic manifolds. We tend also study the integrability of the distributions involved in the definition of the submersions and the geometry of their leaves. Moreover, we get necessary and sufficient conditions for these submersions to be totally geodesic, and provide some representative examples of conformal hemi-slant submersions.
장애인을 위한 유비쿼터스 헬스케어시스템의 설계 및 구현
Vinay Singh,임효택(Hyotaek Lim),박수현(Su-Hyun Park),정완영(Wan-Young Chung) 한국멀티미디어학회 2006 한국멀티미디어학회 학술발표논문집 Vol.2006 No.1
본 논문은 장애인을 위해 착용할 수 있는 눈 깜빡임에 기반을 둔 새로운 헬스케어 시스템에 대해 제시한다. 이 시스템은 세계적으로 널리 퍼져있는 루게릭병(ALS)과 같이 근육신경이 마비되어 자신의 의사를 표현하지 못해 고통받고 있는 환자들을 위해 고안되었다. 본 헬스케어 시스템은 크게 안경에 부착할 수 있는 센서 모듈, 적외선 무선통신을 위한 통신모듈, 컴퓨터에서 동작되는 키보드 소프트웨어 모듈로 나누어져 있으며 주요 특징으로는 컴퓨터에서 동작하는 키보드 소프트웨어의 커서 동작을 눈의 깜빡임으로 쉽게 조절할 수 있게 하는 것에 있다. 장애인이 전달하고 싶어하는 메시지는 인터넷에 의해 가족이나 헬스케어 전문가의 PDA로 전송된다.
Immunotherapy Targeting 4-1BB and Its Ligand
Vinay, Dass S.,Kwon, Byoung S. Springer-Verlag 2006 International journal of hematology Vol.83 No.1
<P>T-cell activation in the absence of costimulation is futile because T-cells deprived of costimulatory signals enter a state of unresponsiveness or anergy. The interaction of 4-1BB and 4-1BB ligand (4-1BBL) activates an important costimulatory pathway with diverse and important roles in immune regulation. Signals relayed through 4-1BB generate strong CD8(+) T-cell responses rather than CD4(+) T-cell responses; this action results in cytokine induction and promotes T-cell survival. In recent years, 4-1BB-mediated immune regulation has gained great significance because of the seemingly contradictory dual roles of agonistic anti-4-1BB in vivo disease models. To date, agonistic 4-1BB monoclonal antibody has shown therapeutic potential against a variety of tumors, CD4(+) T-cell-mediated autoimmune diseases, and chronic graft-versus-host disease. In addition, blockade of 4-1BB/4-1BBL interaction has produced therapeutic effects against coxsackievirus-induced myocardial inflammation, herpetic stromal keratitis, and graft rejection. We propose that the dual roles of agonistic anti-4-1BB--an enhanced effector function and a suppressor function--are mediated by a novel CD11c(+)CD8(+) T-cell population.</P>
TNF superfamily: Costimulation and clinical applications
Vinay, Dass S.,Kwon, Byoung S. Elsevier 2009 Cell biology international Vol.33 No.4
<P><B>Abstract</B></P><P>The molecules concerned with costimulation belong either to the immunoglobulin (Ig) or tumor necrosis factor (TNF) superfamily. The tumor necrosis superfamily comprises molecules capable of providing both costimulation and cell death. In this review we briefly summarize certain TNF superfamily receptor–ligand pairs that are endowed with costimulatory properties and their importance in health and disease.</P>
Vinay Prasad Mandal,Sufia Rehman,Raihan Ahmed,Md. Masroor,Pavan Kumar,Haroon Sajjad 대한공간정보학회 2020 Spatial Information Research Vol.28 No.5
The main objective of the study is to assess land suitability for suggesting suitable crop sequences in Katihar district of Bihar, India. We first selected site-specific factors and assigned their weights using analytical hierarchy process (AHP) for land suitability assessment. The layers of factors were integrated to prepare land suitability map. The findings revealed that of the total area (3.05 million ha), the largest area (48.5%) was marginally suitable for agriculture followed by moderately suitable (30.8%) and highly suitable (2.9%). Nearly 17.8% area was found unsuitable for agriculture. Rice–maize– rice, rice–maize–jute and maize–maize–rice were found suitable crop sequences in all suitability classes. Multilinear regression analysis between land suitability and factors shows that soil texture, nitrogen, phosphorus and potassium, pH and drainage proximity influenced land suitability. The study suggested soil reclamation, application of adequate amount of fertilizers, assured irrigation and flood control for sustainable crop sequences in the study area. Land restoration and soil reclamation measures should be taken to transform unsuitable areas for crop cultivation. Use of integrated geographical information system and AHP approach for analyzing land suitability and crop sequences may add a new dimension in spatial information science.
Origins and functional basis of regulatory CD11c<sup>+</sup>CD8<sup>+</sup> T cells
Vinay, Dass S.,Kim, Chang H.,Choi, Beom K.,Kwon, Byoung S. WILEY-VCH Verlag 2009 European journal of immunology Vol.39 No.6
<P>Previously, we showed that CD11c defines a novel subset of CD8<SUP>+</SUP> T cells whose in vivo activity is therapeutic for arthritis; however, the mechanisms directing their development, identity of their precursors, and basis of their effector function remain unknown. Here, we show that the novel subset develops from CD11c<SUP>surface−</SUP>CD8<SUP>+</SUP> T cells and undergoes robust expansion in an antigen- and 4-1BB (CD137)-dependent manner. CD11c<SUP>+</SUP>CD8<SUP>+</SUP> T cells exist in naïve mice (<3%) with limited suppressive activity. Once activated, they suppress CD4<SUP>+</SUP> T cells in vivo and in vitro. Suppression of CD4<SUP>+</SUP> by CD11c<SUP>+</SUP>CD8<SUP>+</SUP> T cells is related to an increase in IDO activity induced in competent cells via the general control non-derepressible-2 pathway. CD11c<SUP>+</SUP>CD8<SUP>+</SUP> T cells are refractory to the effect of IDO but constrict in a novel 1-methyl D,L-tryptophan-dependent mechanism resulting in reversal of their suppressive effects. Thus, our data uncover, for the first time, the origin, development, and basis of the suppressive function of this novel CD11c<SUP>+</SUP>CD8<SUP>+</SUP> T-cell subpopulation that has many signature features of Treg.</P>
Numerical investigation of a star's trajectory in binary Quasar system
VINAY KUMAR,BEENA R GUPTA,RAJIV AGGARWAL 장전수학회 2016 Advanced Studies in Contemporary Mathematics Vol.26 No.3
In this paper, we have considered Time-Frequency analysis (TFA) based on wavelets for the identification and classification of trajectories in a nonlinear dynamical model. Time-Frequency Analysis (TFA) is the relatively fast method. Ridge-plots (Time-frequency landscape) obtained from Time-Frequency Analysis (TFA) extracts instantaneous frequency from the phase of continuous wavelet transform (CWT). The nonlinear model considered in the analysis is the binary system of quasars hosted in the pair of interacting disk galaxies introduced recently. We have characterized the different type of trajectories like periodic, quasi-periodic, chaotic sticky, chaotic non-sticky, weakly and strongly chaotic. We have shown a comparative study between Time-Frequency Analysis (TFA) and a well-established method Lyapunov Characteristic Exponent (LCE). We have also presented the graphs explaining the phenomenon of transient chaos and resonance trapping.