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      • A Web-based Networked Display User Interface for Smart Meeting Spaces

        Vinay Rarnachandra,Changhyeok Bae,JongWon Kim 한국정보과학회 2008 한국정보과학회 학술발표논문집 Vol.35 No.2

        With the recent advances in ubiquitous computing environment there have been ongoing efforts to provide a scalable and elegant multi-party collaboration solution. SMeet (smart meeting space) is one such solution that offers an effective multi-party remote collaboration environment. Such meeting spaces may consist of heterogeneous display systems like networked tiled display, projector display and so on. In this paper we explore a flexible and easy-to-use web-based user interface tool for networked display control and management under the SMeet environment. We describe its design based on networked display and service-oriented Web 2.0 principles. Also, prototype implementation is made and evaluated to verify its usefulness.

      • VALUES BASED BUSINESS ETHICS ALONG THE ENTIRE VALUE CHAIN- A DEMONSTRATION OF THE DEFINITION OF MARKETING

        Vinay Sharma,Anita Sengar,Rajat Agrawal,Kumkum Bharti 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

        This paper is demonstrative of values and the imbibed strength of values observed along the value chains of organizations studied by the authors in past two years. The paper is projective of an intense relationship of values based business ethics observed along the value chains of the organizations concerned with the context and the soul of the conventional definition of marketing given by American Marketing Association in 2007. The value chain of a prominent consumer product’s marketers studied through reflexive research approach exemplifies that how business ethics based on values helped in evolving activities, institutions and processes for creating, communicating, delivering and exchanging offerings that have value for the customers, clients, partners and society at large which is actually the definition of marketing be American Marketing Association: Marketing is the activity, set of institutions, and processes for creating, communicating, delivering, and exchanging offerings that have value for customers, clients, partners, and society at large. (Approved July 2013) Similar observations in the value chains and the marketing process of other organizations validated the fact that if values driven business ethics is followed along the value chain the context of 2007 definition of Marketing gets enlivened.

      • SCIESCOPUSKCI등재

        C<SUB>60</SUB>@MWCNT: Room Temperature Encapsulation of C<SUB>60</SUB> into Multiwall Carbon Nanotubes

        Vinay Gupta,Om P. Bahl,Rakesh B. Mathur 한국탄소학회 2010 Carbon Letters Vol.11 No.1

        The synthesis of C60@MWCNT was carried out at room temperature (~25℃) from arc-discharge prepared Multi-wall carbon nanotubes (MWCNTs). They were oxidized and acid treated for tube opening. Then C60 molecules were encapsulated into MWCNTs by wetting them with C60-toluene solution for several minutes followed by ultrasonification. C60@MWCNT was cleaned by pure toluene to remove any excess C60. C60@MWCNT was characterized by electron microscopy, which showed large scale filling of C60 into MWCNTs. It was observed that the mechanism of insertion of C60 into MWCNTs may be due to the capillary suction at the opening ends of MWCNTs.

      • KCI등재

        The Prevalence of Chronic Obstructive Pulmonary Disease and the Determinants of Underdiagnosis in Women Exposed to Biomass Fuel in India- a Cross Section Study

        Vinay KalagoudaMahishale,Naveen Angadi,Vjayanand metgudmath,Mitchelle Lolly,Ajith Eti,Sujeer Khan 전남대학교 의과학연구소 2016 전남의대학술지 Vol.52 No.2

        Background and Objectives: Tobacco smoking has been established as a major risk factorfor chronic obstructive pulmonary disease (COPD) in women of developing countries,but emerging evidence suggests that biomass fuel is an important risk factor aswell. The primary objective of the study was to find the true prevalence of COPD inIndian women exposed to biomass fuel using spirometry. We also aimed to find the determinantsof underdiagnosis of COPD in these participants. Methods: Women with a history of exposure to biomass fuel for >10 years were screenedfor COPD using spirometry following all standard protocols as per GOLD/ATS/ERSdefinitions. Results: Of the 2868 women screened, a total of 529 (18.4%) women were confirmedto have COPD in which 123 (4.2%) were “Women with known COPD” and 406 (14.2%)“Women with new COPD”. The mean age at the time of Diagnosis was 61±5.2 and 47±3.6respectively. The duration of exposure to biomass fuel had a great impact on the riskof COPD with OR 1.2, 95% CI (1.1-1.9) for patients with 10-15 years exposure and OR2.9, 95% CI (2.5-3.1) for exposure >25 years, p<0.001. Conclusion: The prevalence of COPD among women exposed to biomass fuel is veryhigh. A strong correlation was found between the risk of COPD and the duration of exposurealong with the age at which the exposure to biomass fuel begins. Underdiagnosisof COPD was frequent in women due to the lack of the availability of spirometry, lackknowledge of hazards of biomass fuel, a low level of education and the ignorance of thehealth care provider being the important determinants of underdiagnosis.

      • KCI등재

        Performance analysis and comparison of various machine learning algorithms for early stroke prediction

        Vinay Padimi,Venkata Sravan Telu,Devarani Devi Ningombam 한국전자통신연구원 2023 ETRI Journal Vol.45 No.6

        Stroke is the leading cause of permanent disability in adults, and it can cause permanent brain damage. According to the World Health Organization, 795,000 Americans experience a new or recurrent stroke each year. Early detection of medical disorders, for example, strokes, can minimize the disabling effects. Thus, in this paper, we consider various risk factors that contribute to the occurrence of stoke and machine learning algorithms, for example, the decision tree, random forest, and naive Bayes algorithms, on patient characteristics survey data to achieve high prediction accuracy. We also consider the semisupervised self-training technique to predict the risk of stroke. We then consider the near-miss undersampling technique, which can select only instances in larger classes with the smaller class instances. Experimental results demonstrate that the proposed method obtains an accuracy of approximately 98.83% at low cost, which is significantly higher and more reliable compared with the compared techniques.

      • KCI등재

        Importance of Imidazolidinone Motif in 4-Phenyl-N-arylsulfonylimidazolidinone for their Anticancer Activity

        Vinay K. Sharma,이기철,Cheonik Joo,Niti Sharma,정상헌 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.8

        To investigate the possible isosteric replacement of imidazolidinone moiety in 4-phenyl-N-arylsulfonylimidazolidinone for broad and potent anticancer agents, a series of 4-phenyl-l(N)-arylsulfonylimidazolidinones 6ak,imidazolidinethione analogs 7a-i, and imidazolidine oxime analogs 8a-c were prepared and evaluated for their in vitro anticancer activity against four human cancer cell lines (human lung A549, human colon COLO205, human leukemia K562, human ovary SK-OV-3). Among all the derivatives of N-arylsulfonylimidazolidinone 6a-k, compounds 6f and 6g showed the best inhibition comparable to doxorubicin against all cancer cell lines. Increasing the carbon chain on alkyl moieties of carbamates as shown in 6c-g did not alter the activity. The imidazolidinethione analogs 7a-i and imidazolidin-2-one oxime derivatives 8a-c did not possess any good activity. Therefore, imidazolidinone moiety is the best pharmacophore among the 4-phenyl-Narylsulfonylimidazolidinone derivatives.

      • SCISCIESCOPUS

        Toxicity and dose determination of quillaja saponin, aluminum hydroxide and squalene in olive flounder (Paralichthys olivaceus)

        Vinay, T.N.,Park, C.S.,Kim, H.Y.,Jung, S.J. Elsevier 2014 Veterinary immunology and immunopathology Vol. No.

        Adjuvants are substances added to vaccines to enhance the immune response of a given antigen. Most of the adjuvants are toxic at certain doses, and toxicity varies in different species. Moreover, there are no standard dosage limits set for adjuvant use in fish vaccines. We evaluated the acute toxicity, serum enzymes (AST/ALT) indicating hepatic injury and histopathological changes due to intra-peritoneal administration of different concentrations of a panel of adjuvants including quillaja saponin, aluminum hydroxide, squalene emulsion and Freund's incomplete adjuvant (FIA) with a dose ranging study of saponin (500, 160, 50, 16 and 5μgfish<SUP>-1</SUP>), aluminum hydroxide (5000, 1600, 500, 160 and 50μgfish<SUP>-1</SUP>), squalene emulsion (20, 10 and 5%), and FIA to determine the acceptable dosage for vaccination in olive flounder (Paralichthys olivaceus) fingerlings measuring 4.66+/-0.41g, 8.47+/-0.42cm. Saponin was highly toxic with a LD<SUB>50</SUB> of approximately 105μgfish<SUP>-1</SUP> (22.4mgkg<SUP>-1</SUP>) causing severe histological damage and AST level was high at dose above 16μgfish<SUP>-1</SUP> and ALT, specific for liver damage was high only at 160μgfish<SUP>-1</SUP> (11U/L) and was safe at 5μgfish<SUP>-1</SUP>. Aluminum hydroxide was toxic at 5000μgfish<SUP>-1</SUP> and was acceptable at dose below 1600μgfish<SUP>-1</SUP> with moderate histology and AST/ALT levels similar with control. Squalene emulsion showed increased inflammation at 20% and 10% emulsions and the inflammatory response was mild at a concentration of 5% oil emulsion and AST/ALT levels being similar to control in 10% and 5% emulsions and elevated in 20% on both sampling days. FIA was not lethal, but induced severe inflammation at injection site and around blood vessels. In comparison to FIA, saponin found to be safe at dose of 5μgfish<SUP>-1</SUP>, aluminum hydroxide below 1600μgfish<SUP>-1</SUP>, and squalene at 5% emulsion and could be accepted for vaccination studies. These results provide an insight for the selection of safer dose of adjuvants for intra-peritoneal vaccination of olive flounder.

      • SCIESCOPUS

        Immunotherapy of cancer with 4-1BB.

        Vinay, Dass S,Kwon, Byoung S American Association for Cancer Research, Inc 2012 Molecular Cancer Therapeutics Vol.11 No.5

        <P>4-1BB (CD137), a member of the TNF receptor superfamily, is an activation-induced T-cell costimulatory molecule. Signaling via 4-1BB upregulates survival genes, enhances cell division, induces cytokine production, and prevents activation-induced cell death in T cells. The importance of the 4-1BB pathway has been underscored in a number of diseases, including cancer. Growing evidence indicates that anti-4-1BB monoclonal antibodies possess strong antitumor properties, which in turn are the result of their powerful CD8+ T-cell activating, IFN-γ producing, and cytolytic marker-inducing capabilities. In addition, combination therapy of anti-4-1BB with other anticancer agents, such as radiation, has robust tumor-regressing abilities against nonimmunogenic or poorly immunogenic tumors. Furthermore, the adoptive transfer of ex vivo anti-4-1BB-activated CD8+ T cells from previously tumor-treated animals efficiently inhibits progression of tumors in recipient mice that have been inoculated with fresh tumors. In addition, targeting of tumors with variants of 4-1BBL directed against 4-1BB also have potent antitumor effects. Currently, a humanized anti-4-1BB is in clinical trials in patients with solid tumors, including melanoma, renal carcinoma, and ovarian cancer, and so far seems to have a favorable toxicity profile. In this review, we discuss the basis of the therapeutic potential of targeting the 4-1BB-4-1BBL pathway in cancer treatment.</P>

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