Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis

Sato, Chihiro,Takahashi, Kazuya,Sato, Hiroki,Naruse, Takumi,Nakajima, Nao,Takatsuna, Masafumi,Mizuno, Ken-ichi,Hashimoto, Satoru,Takeuchi, Manabu,Yokoyama, Junji,Kobayashi, Masaaki,Terai, Shuji The Korean Gastric Cancer Association 2022 Journal of gastric cancer Vol.22 No.-

Purpose: Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods: A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results: Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs.Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions: Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis.

Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis

Sato Chihiro,Takahashi Kazuya,Sato Hiroki,Naruse Takumi,Nakajima Nao,Takatsuna Masafumi,Mizuno Ken-ichi,Hashimoto Satoru,Takeuchi Manabu,Yokoyama Junji,Kobayashi Masaaki,Terai Shuji 대한위암학회 2022 Journal of gastric cancer Vol.22 No.4

Purpose Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs. Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis. Purpose Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs. Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis.

Consensus Control of Multi-agent Systems Over Undirected Graphs with Quantized Signal Communication

Takumi Furusaka,Takao Sato,Nozomu Araki,Yasuo Konishi 제어로봇시스템학회 2018 제어로봇시스템학회 국제학술대회 논문집 Vol.2018 No.10

This study proposes a new design method for the consensus control of multi-agent systems with quantized signal communication. When the static quantizer used, the performance of the consensus control is deteriorated depending on the quantizing level. In a conventional method, the quantization is implemented the probability function. On the other hand, in the proposed method, the dynamic quantizer is introduced, and it is optimally designed. As a result, the consensus control performance is improved. Finally, the effectiveness of the proposed method is demonstrated through numerical examples.

Endoscopy and Imaging Modalities/Basic Science of Gastrointestinal Disorders/Miscellaneous : Hemodynamic Evaluation Of Esophageal Varices Resistant To Injection Sclerotherapy By Endoscopic Ultrasonography

( Talcahiro Sato ),( Katsu Yamazaki ),( Jouji Toyota ),( Yoshiyasu Karino ),( Takumi Ohmura ),( Toshihim Suga ) 대한소화기학회 2007 SIDDS Vol.9 No.-

Background/Aims: We evaluated hemodynamics of esophageal varices that were resistant to endoscopic injection sclerotherapy (EIS) Using 5% ethanolamine oleate with iopamidol (5% EOI) and in need of EIS using absolute alcohol (AA). Methods: Consecutive 490 patients who underwent hemodynamic evaluation using endoseopic color Doppler ultrasonography (ECDUS) and ultrasonic microprobe (UMP) were studied. Results: Nine patients were resistant to EIS using 5% EOI and the additional use of AA in this group was performed (AA group). Various parameters were compared between the 481 patients who had been administered EIS using 5% EOI (EO group) and the 9 patients in AA group. The mean number of EIS treatments in the AA group (6.8±3.4) was significantly greater than in the EO group (4.4±2.1 times) (p<0.01). The mean amount of 5% EOI provided in the AA group (31.1±17.4 mL) was significantly larger than in the EO group (14.9±8.8 mL) (P<0.001). The mean velocity of esophageal varices in the AA group (13.6±3.2 cm/s) was significantly higher than in the EO group (9.4±3.1 cm/s) (P<0.001) determined by ECDUS. The mean diameter of esophageal varices as found by UMP was 8.0±3.5 mm in the AA group and 4.6±2.4 mm in the EO group, with the difference being significant (p<0.01). The mean diameter of the perforating vein was 3.8±1.9 mm in the AA group and 2.1±0.5 mm in the EO group as shown by UMP, a difference that was statistically significant (p<0.01). Conclusions: Hemodynamic evaluation revealed that the esophageal varices were more severe in the AA group than in the EO group.

Repairability Performance and Restoring Force Characteristics of Damaged H-shaped Steel Members after Repair

Mori, Kenjiro,Ito, Takumi,Sato, Hanako,Munemura, Hiroka,Matsumoto, Takeshi,Choi, Changhoon Council on Tall Building and Urban Habitat Korea 2015 International journal of high-rise buildings Vol.4 No.1

Recently, new keywords such as "Resilience" and "Repairability" have been discussed from the perspective of the sustainability of damaged structures after a severe disaster. To evaluate the repairability and recovery of structures, it is necessary to establish an analytical method that can simulate the behavior of repaired structures. Furthermore, it is desirable to establish an evaluation method for the structural performance of repaired structures. This study investigates the repairability and recovery of steel members that are damaged by local buckling or cracks. This paper suggests a simple analytical model for repaired steel members, in order to simulate the inelastic behavior and evaluate the recoverability of the structural performance. There is good agreement between the analytical results and the test results. The proposed analytical method and model can effectively evaluate the recoverability.

Case Study of Landslide Monitoring based on GNSS measurement and LiDAR Analysis

( Shuhei Abe ),( Norio Oikawa ),( Tomoyuki Takami ),( Takumi Sato ),( Sakae Mukoyama ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

Recently, the application of GNSS measurement and LiDAR analysis at landslide sites has been increasing in Japan. In 2018, a large scale landslide occurred at Agatsu, Fukushima Pref., Japan, during snow-melting period. The field reconnaissance assumed the high speed displacement at site. To investigate the displacement behavior of the ground surface in the whole area, we conducted Image matching analysis using LiDAR-DEM data of two different time periods. Furthermore, we also conducted observation by a statistical analysis based on GNSS measurement in order to observe the mm-order displacement in real time. As result, two areas were detected in this site, which had different trends in the displacement direction and the displacement amount. The cumulative displacement and the displacement velocity of the river facing area were ~4 m and ~28 mm/h as of June 12th 2018, respectively. The failure of the site was forecasted to occur within few days, but GNSS measurement observation showed that the displacement was converged as result from applying emergency countermeasures such as deep wells. The case study shows the effective application of GNSS measurement and LiDAR analysis in monitoring the behavior of the landslide site.

New and noteworthy records of the moss flora of Korea

김원희,Masanobu Higuchi,Tomio Yamaguchi,Takumi SATO,Yuya INOUE 한국식물분류학회 2020 식물 분류학회지 Vol.50 No.4

A total of 34 taxa, 33 species and one variety, are newly added to the moss checklist of Korea. They were collected on Jejudo Island, Samcheok limestone areas in Gangwon Province, and Socheongdo Island from 2015 to 2018 and organized into 19 families and 26 genera. Additionally, eight genera are new to Korea. This study verifies the distributions of nine species whose distributions and specimens have remained unknown thus far. Finally, two unrecorded taxa, consisting of one species and one variety, are identified by reexamining Korean specimens deposited at the National Museum and Science in Japan (TNS). The specimens were collected in 1942 and 1940 from Mt. Baekdusan and Anbyun in North Korea.