Total Heart Valve Replacement Surgeries and a New Hingeless Valve

Wada, Juro 최신의학사 1969 最新醫學 Vol.12 No.1

CLINICAL EVALUATION OF POSITRON EMISSION TOMOGRAPHY USING O-15C02 , O-1502 AND C-11CO

Wada, Makoto,Ichiya, Yuichi,Kuwabara, Yasuo,Ayabe, Zenji,Katsuragi, Makoto,Matsuura, Keiichi 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1

古墳群の把握と理解 -日本の事例を中心に-

( Wada Seigo ) 공주대학교 백제문화연구소 2013 백제문화 Vol.1 No.48

필자는 일본열도 고분시대(3세기 중엽∼6세기 말)의 정치사회사를 연구의 한 테마로 하고 있다. 그 과정에서 열도의 각지에 만들어진 20만기 전후의 고분(전방후원분, 전방후방분, 원분, 방분의 4가지가 기본형)을 어떤 단위, 또는 그룹으로 파악하고 축조상황(성립·지속·이동·소멸이나 동시기의 조합 등)을 어떻게 이해하느냐가 매우 큰 문제가 되고 있다. 여기에서는 이러한 과제에 필자가 임해 온 방법과 작업의 실제 개요를 보고하고자 한다. 고분시대의 시기구분, 계층구분, 지역구분을 명확히 하면서 일정한 나름대로의 해석을 추가하여 논의를 진행하지만, 작업이 아직 완료된 것이 아니기 때문에 마지막에 약간의 과제와 전망을 덧붙였다. 특히, 아직도 논의가 불충분한 고분의 구분과 지역 구분의 문제는 사람(또는 집단)의 구분과 밀접한 관계가 있기 때문에 신중한 검토가 요구된다. 목적의식에 따라 방법론을 연마하며, 고고자료를 열심히 분석하고, 가설을 세우고, 그것을 끊임없이 검증하는 작업이 중요하다고 생각한다. The writer of this article studies political and social history of Gohun Period(middle of the 3rd to late 6th century AD) in Japan. It is important how to categorize numerous tombs(keyhole-shaped tombs, double squareshaped tombs, circular tombs and square-shaped tombs) about two hundreds thousands by appropriate units and groups, and to understand their construction situation; development, maintain, transfer and extinction of the tombs. This study presents the methods and preliminary results of these issues. It is discussed to clarify the period, hierarchy and region, and new interpretation is added. Further issues and prospects are also included in conclusion as the research is still ongoing. It is necessary to consider the classification and regional issues carefully because they reflect the people or community relating to the tombs. In addition, it is very important to analyse archaeological data, frame a hypothesis and verify it challenging to methodologies according to own objectives.

Actin-mediated movement of chloroplasts

Wada, Masamitsu,Kong, Sam-Geun The Company of Biologists Ltd. 2018 Journal of cell science Vol.131 No.2

<P>Plants are sessile and require diverse strategies to adapt to fluctuations in the surrounding light conditions. Consequently, the photorelocation movement of chloroplasts is essential to prevent damages that are induced by intense light (avoidance response) and to ensure efficient photosynthetic activities under weak light conditions (accumulation response). The mechanisms that underlie chloroplast movements have been revealed through analysis of the behavior of individual chloroplasts and it has been found that these organelles can move in any direction without turning. This implies that any part of the chloroplast periphery can function as the leading or trailing edge during movement. This ability is mediated by a special structure, which consists of short actin filaments that are polymerized at the leading edge of moving chloroplasts and are specifically localized in the space between the chloroplast and the plasma membrane, and is called chloroplast-actin. In addition, several of the genes that encode proteins that are involved in chloroplast-actin polymerization or maintenance have been identified. In this Review, we discuss the mechanisms that regulate chloroplast movements through polymerization of the chloroplast-actin and propose a model for actin-driven chloroplast photorelocation movement.</P>

ROLE OF SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY FOR DETECTING LIVER TUMORS

Wada, Makoto,Ichiya, Yuichi,Kuwabara, Yasuo,Ayabe, Zenji,Katsuragi, Makoto,Matsuura, Keiichi 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1

The effect of daily calf stroking frequency during the postnatal period on the establishment of the human-calf relationship

Wada, Satoko,Fukasawa, Michiru,Chiba, Takashi,Shishido, Tetsuro,Tozawa, Akitsu,Ogura, Shin-ichiro Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.10

Objective: Stroking calves during the postnatal period could effectively improve human-calf relationships. The objective of this study is to examine how daily calf stroking frequency during the postnatal period affects the establishment of human-calf relationships. Methods: Six calves were stroked by a trainer for 6 minutes once daily for 5 days after birth (D1). Six calves were stroked by a trainer for 3 minutes twice daily for 5 days after birth (D2). A further four calves were stared at but not stroked as the control group. The overall stroking or staring duration was the same for all groups, at 6 min/d and 30 min over 5 days. The tests for reactions to the stationary trainer in an unfamiliar environment and avoidance distance measurements for an approaching trainer were conducted at 1 month and 3 months after the treatment. Results: Calves in both stroking groups approached significantly closer to the stationary trainer, vocalized less, and looked at the trainer shorter than the control group at 1 month. However, at 3 months, there was no significant difference between the D1 and the control group, whereas the D2 approached significantly closer to the trainer and vocalized less, and looked at the trainer for a shorter time than the control group. For the avoidance distance, the trainer could approach closer to both stroking groups than the control at 1 month, however, there was no difference among groups at 3 months. Conclusion: Our results suggested that the difference in the calf stroking procedure affected the established human-calf relationships, even though the total stroking duration was the same for all stroked calves. It is likely to be more effective to stroke more frequently than intensively when the aim is to establish better human-calf relationships within limited labor time.

A CHARACTERIZATION OF THE VANISHING OF THE SECOND PLURIGENUS FOR NORMAL SURFACE SINGULARITIES

Wada, Koukichi Korean Mathematical Society 2008 대한수학회보 Vol.45 No.2

In the study of normal (complex analytic) surface singularities, it is interesting to investigate the invariants. The purpose of this paper is to give a characterization of the vanishing of ${\delta}_2$. In [11], we gave characterizations of minimally elliptic singularities and rational triple points in terms of th.. second plurigenera ${\delta}_2$ and ${\gamma}_2$. In this paper, we also give a characterization of rational triple points in terms of a certain computation sequence. To prove our main theorems, we give two formulae for ${\delta}_2$ and ${\gamma}_2$ of rational surface singularities.

도일 후 손창섭의 법적 지위—사망 전후 발행 공적 서류를 근거로

WADA Tomomi 한국현대문학회 2023 한국현대문학연구 Vol.- No.70

This article attempts to verify the legal status of Son Chang-seop at Japan. It is commonly believed that he was naturalized in Japan, but no legal documents have been found to prove his naturalization. The only evidence is the testimony of his wife. The purpose of this article was to reveal his nationality based on several official documents issued in Japan before and after his death in 2010. In addition to the official documents, with reviewing his serialized novel “Yumaeng”, the aspects of the life for him and his family at Japan are clarified. Their life is known to have been very frugal. This is because he and his wife lived in a small public housing. However, the Son’s family lived in the apartment in Tokyo 23 wards at first, and then moved to a public housing in their 50s. Considering the special significance of living in a public complex in the 1980s Japan, this cannot be attributed to economic difficulties. At that time, residents of public housing tended to live temporarily to save money on living expenses while aiming for desirable housing. Similarly, for Son’s family, living in a public housing was a passage to a desirable living environment in later life. However, Son himself did not accept his family’s suggestion and died in a public housing. As for the nationality issue, there is no legal evidence that the family’s wishes were fulfilled. In public documents issued before and after his death in 2010, Son was listed only as a foreign spouse of a Japanese. Japanese are removed from family register upon death. However, there is no record that Son was removed from family register. This indicates that he was never a Japanese citizen. Only the person himself can change his nationality, and it is not possible to change it after death. This brings us to the conclusion of our discussion of Son’s nationality.

Synthesis of Anatase Phase Titanium Dioxide Using High-Power Nd:YAG Laser Focused on Titanium Wire in Water

Wada, Naoyuki,Kim, Chang-Hwan,Yoh, Jack J.,Hamashima, Hideki,Hokamoto, Kazuyuki The Japan Institute of Metals 2012 Materials Transactions Vol.53 No.1

<P>An experimental method to synthesize titanium dioxide (TiO<SUB>2</SUB>) using high-power laser in water was performed. A high-power Nd:YAG pulsed laser was used for the synthesis, with the laser energy fixed at 1 J/pulse. This laser was focused on a titanium wire set in water. This investigation recovered nano-sized anatase phase titanium dioxide with well crystallized structure. Pulsed bubbles generated in the water were confirmed by optical measurement, and their collapse may have induced high pressures and temperatures. The bubbles generated was approximately spherical in shape, with an estimated maximum size of 3.7 mm generated about 200 µs later after focusing the laser. Recovered powders were confirmed as single anatase phase titanium dioxide by XRD analysis. Effects of bubbles on synthesis and crystallization are also suggested.</P>

Multivalent mannose-decorated NIR nanoprobes for targeting pan lymph nodes

Wada, Hideyuki,Hyun, Hoon,Bao, Kai,Lee, Jeong Heon,El Fakhri, Georges,Choi, Yongdoo,Choi, Hak Soo Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.340 No.-

<P><B>Abstract</B></P> <P>Lymphadenectomy is a prerequisite for most malignancies to define the precise staging of cancer, as well as resect the possible metastases completely. While it improves prognosis, lymphadenectomy often causes postoperative edema or bleeding because of unclear surgical margins. In this study, we synthesized near-infrared (NIR) fluorescent nanoprobes with conjugating various mannose moieties on the surface to target macrophages in the lymph node. Armed with these NIR nanoprobes, we demonstrated the feasibility of intraoperative pan lymph nodes (PLN) mapping and real-time optical imaging under the NIR fluorescence imaging system. We found that even single mannose-conjugated ZW800-1 showed specific uptake in lymph nodes within 4 h, and multiple mannose-employed polyrotaxanes highlighted PLN efficiently with low background signals in major organs. This technology can help surgeons perform lymphadenectomy with ease and safety by identifying all regional lymph nodes proficiently after a single intravenous injection of NIR nanoprobes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> NIR fluorescent nanoprobes to target macrophages in the lymph node. </LI> <LI> Renal clearable nanoprobes enhance the SBR of target tissue. </LI> <LI> Intraoperative pan lymph nodes mapping is demonstrated. </LI> <LI> Surgeons can perform lymphadenectomy with ease and safety using NIR. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>