Measurement of Intra-Fraction Displacement of the Mediastinal Metastatic Lymph Nodes Using Four-Dimensional CT in Non-Small Cell Lung Cancer

Suzhen Wang,Jianbin Li,Yingjie Zhang,Wei Wang,Fengxiang Li,Tingyong Fan,Min Xu,Qian Shao 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.4

Objective: To measure the intra-fraction displacements of the mediastinal metastatic lymph nodes by using four-dimensional CT (4D-CT) in non-small cell lung cancer (NSCLC). Materials and Methods: Twenty-four patients with NSCLC, who were to be treated by using three dimensional conformal radiation therapy (3D-CRT), underwent a 4D-CT simulation during free breathing. The mediastinal metastatic lymph nodes were delineated on the CT images of 10 phases of the breath cycle. The lymph nodes were grouped as the upper, middle and lower mediastinal groups depending on the mediastinal regions. The displacements of the center of the lymph node in the left-right (LR), anterior-posterior (AP), and superior-inferior (SI) directions were measured. Results: The mean displacements of the center of the mediastinal lymph node in the LR, AP, and SI directions were 2.24 mm, 1.87 mm, and 3.28 mm, respectively. There were statistically significant differences between the displacements in the SI and LR, and the SI and AP directions (p < 0.05). For the middle and lower mediastinal lymph nodes, the displacement difference between the AP and SI was statistically significant (p = 0.005; p = 0.015), while there was no significant difference between the LR and AP directions (p < 0.05). Conclusion: The metastatic mediastinal lymph node movements are different in the LR, AP, and SI directions in patients with NSCLC, particularly for the middle and lower mediastinal lymph nodes. The spatial non-uniform margins should be considered for the metastatic mediastinal lymph nodes in involved-field radiotherapy. Objective: To measure the intra-fraction displacements of the mediastinal metastatic lymph nodes by using four-dimensional CT (4D-CT) in non-small cell lung cancer (NSCLC). Materials and Methods: Twenty-four patients with NSCLC, who were to be treated by using three dimensional conformal radiation therapy (3D-CRT), underwent a 4D-CT simulation during free breathing. The mediastinal metastatic lymph nodes were delineated on the CT images of 10 phases of the breath cycle. The lymph nodes were grouped as the upper, middle and lower mediastinal groups depending on the mediastinal regions. The displacements of the center of the lymph node in the left-right (LR), anterior-posterior (AP), and superior-inferior (SI) directions were measured. Results: The mean displacements of the center of the mediastinal lymph node in the LR, AP, and SI directions were 2.24 mm, 1.87 mm, and 3.28 mm, respectively. There were statistically significant differences between the displacements in the SI and LR, and the SI and AP directions (p < 0.05). For the middle and lower mediastinal lymph nodes, the displacement difference between the AP and SI was statistically significant (p = 0.005; p = 0.015), while there was no significant difference between the LR and AP directions (p < 0.05). Conclusion: The metastatic mediastinal lymph node movements are different in the LR, AP, and SI directions in patients with NSCLC, particularly for the middle and lower mediastinal lymph nodes. The spatial non-uniform margins should be considered for the metastatic mediastinal lymph nodes in involved-field radiotherapy.

Detecting the weak damped oscillation signal in the agricultural machinery working environment by vibrational resonance in the duffing system

Suzhen Wang,Baochun Lu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.12

The working environment for agricultural machinery is complex and variable. Some weak characteristic damped oscillation signals are extremely difficult to extract and analyze because of their long-term operation in a strong noise environment. The vibration resonance (VR) phenomenon of a second-order Duffing bistable system driven by a weak characteristic damped oscillation signal and a high-frequency harmonic signal was studied. The results indicate that the cooperation between the Duffing damping ratio and attenuation coefficient can induce the VR occurrence of a small-parameter damped oscillation signal. As a result, the energy of the weak characteristic signal becomes stronger, and the VR numerical processing method of the high-frequency weak characteristic damped oscillation signal is provided. On this basis, aiming at the strong noise of agricultural machinery working, taking the weighted kurtosis index as the objective function and supplemented by variational mode decomposition (VMD) technology, a VR-VMD adaptive method based on quantum particle swarm optimization (QPSO) was proposed to extract the weak characteristic damped oscillation signal. Numerical simulation analysis and experiments show that the proposed VR-VMD method is effective in a strong noise environment for agricultural machinery.

An improved cross-correlation method based on wavelet transform and energy feature extraction for pipeline leak detection

Suzhen Li,Xinxin Wang,Ming Zhao 국제구조공학회 2015 Smart Structures and Systems, An International Jou Vol.16 No.1

Early detection and precise location of leakage is of great importance for life-cycle maintenance and management of municipal pipeline system. In the past few years, acoustic emission (AE) techniques have demonstrated to be an excellent tool for on-line leakage detection. Regarding the multi-mode and frequency dispersion characteristics of AE signals propagating along a pipeline, the direct cross-correlation technique that assumes the constant AE propagation velocity does not perform well in practice for acoustic leak location. This paper presents an improved cross-correlation method based on wavelet transform, with due consideration of the frequency dispersion characteristics of AE wave and the contribution of different mode. Laboratory experiments conducted to simulate pipeline gas leakage and investigate the frequency spectrum signatures of AE leak signals. By comparing with the other methods for leak location identification, the feasibility and superiority of the proposed method are verified.

Formation and failure characteristics of a landslide induced by excavation in western Henan, China

Haining Liu,Suzhen Duan,Han Dong Liu,Weiguo Wang,Yujie Jia 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.7

Engineering construction in mountainous areas is a key factor inducing slope failure, whichposes severe threats to life and property safety during construction and operation. Thus, clearunderstanding of slope structure and potential failure mechanisms is of great importance forslope reinforcement. The Shangge landslide, located in a mountainous area of WesternHenan, China, was triggered by excavation along a toll station. The slope was still unstableafter a row of anti-sliding piles were constructed. To clarify the deformation characteristics andfailure mechanism of this landslide and provide reinforcement guidance for slopes with similargeological conditions, a combined method of field investigation, displacement monitoring,and numerical simulation was employed. The results indicate that the natural slope comprisesa dual structure of soil and rock, and that the soil, with poor permeability and high watermoisture, was prone to form a potential sliding surface. Secondly, slope excavation was thedirect triggering factor. Lastly, but most importantly, the preliminary investigation work failed toaccurately expose the potential position of the sliding surface, and the existing anti-slide pilesfailed to cross the potential sliding surface, which made them unable to effectively improveslope stability. The numerical simulation verified that the recommended piles installed on theplatform of level 2 could significantly improve slope stability. Therefore, when carrying outengineering slope design in similar geological environments, the slope structure and materialcomposition should be fully identified, and the influence of groundwater on the slope stabilitystate should be emphasized. These results can provide a reference for similar slopereinforcement designs.

An Efficient PSI-CA Protocol Under the Malicious Model

Jingjie Liu,Suzhen Cao,Caifen Wang,Chenxu Liu 한국인터넷정보학회 2024 KSII Transactions on Internet and Information Syst Vol.18 No.3

Private set intersection cardinality (PSI-CA) is a typical problem in the field of secure multi-party computation, which enables two parties calculate the cardinality of intersection securely without revealing any information about their sets. And it is suitable for private data protection scenarios where only the cardinality of the set intersection needs to be calculated. However, most of the currently available PSI-CA protocols only meet the security under the semi-honest model and can’t resist the malicious behaviors of participants. To solve the problems above, by the application of the variant of Elgamal cryptography and Bloom filter, we propose an efficient PSI-CA protocol with high security. We also present two new operations on Bloom filter called IBF and BIBF, which could further enhance the safety of private data. Using zero-knowledge proof to ensure the safety under malicious adversary model. Moreover, in order to minimize the error in the results caused by the false positive problem, we use Garbled Bloom Filter and key-value pair packing creatively and present an improved PSI-CA protocol. Through experimental comparison with several existing representative protocols, our protocol runs with linear time complexity and more excellent characters, which is more suitable for practical application scenarios.

Molecular cloning and characterization of a novel saltspecific responsive WRKY transcription factor gene IlWRKY2 from the halophyte Iris lactea var. chinensis

Jun Tang,Qingquan Liu,Haiyan Yuan,Yongxia Zhang,Weilin Wang,Suzhen Huang 한국유전학회 2018 Genes & Genomics Vol.40 No.8

Iris lactea var. chinensis is a perennial herbaceous halophyte with high salt tolerance and ornamental value. Previous RNA sequencing analysis revealed a transcription factor gene IlWRKY2 expression was upregulated by salt stress. To obtain the full-length sequence, the basic characteristics of IlWRKY2 and its expression pattern under salt stress. Full-length cDNA of IlWRKY2 was cloned by 3′/5′ RACE based on the intermediate sequence obtained by RNA sequencing analysis. Structure analysis of IlWRKY2 were performed by Compute pI/MW tool, PSIPRED and SWISS-MODEL analysis. Sequence analysis of IlWRKY2 were performed by BLAST program, DNAman software, MEGA software and MEME program. IlWRKY2 expression pattern was analyzed by quantitative real-time polymerase chain reaction. The open reading frame of IlWRKY2 is 1338 bp in length, which encodes a protein of 446 amino acids. Amino acid sequence analysis revealed that the IlWRKY2 contains one WRKY domains with a zinc finger motif C–X5–C–X23–H–X–H. Phylogenetic analysis showed that the IlWRKY2 was much closer to EgWRKY41 from Elaeis guineensis and MaWRKY42 from Musa acuminata subsp. malaccensis. Furthermore, the expression of IlWRKY2 in I. lactea var. chinensis shoots was upregulated by different concentrations of NaCl treatment and increased 16-fold after treatment with 200 mM NaCl for 12 h. Obtained the full-length cDNA of IlWRKY2 which belongs to Group II-b WRKY subfamily. IlWRKY2 expression was obviously induced by salt stress in I. lactea var. chinensis shoots and it may play an important role in halophyte I. lactea var. chinensis adaptation to environmental salt stress.