http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Choi, Yoon Jin,Lee, Dong Ho,Choi, Myung-Gyu,Lee, Sung Joon,Kim, Sung Kook,Song, Geun Am,Rhee, Poong-Lyul,Jung, Hwoon-Yong,Kang, Dae-Hwan,Lee, Yong Chan,Lee, Si Hyung,Choi, Suck Chei,Shim, Ki-Nam,Seol, KOREAN ACADEMY OF MEDICAL SCIENCE 2017 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.32 No.11
<P>This study compared the efficacy of DA-9601 (Dong-A ST Co., Seoul, Korea) and its new formulation, DA-5204 (Dong-A ST Co.), for treating erosive gastritis. This phase III, randomized, multicenter, double-blind, non-inferiority trial randomly assigned 434 patients with endoscopically proven gastric mucosal erosions into two groups: DA-9601 3 times daily or DA-5,204 twice daily for 2 weeks. The final analysis included 421 patients (DA-5204, 209; DA-9601, 212). The primary endpoint (rate of effective gastric erosion healing) and secondary endpoints (cure rate of endoscopic erosion and gastrointestinal [GI] symptom relief) were assessed using endoscopy after the treatment. Drug-related adverse events (AEs), including GI symptoms, were also compared. At week 2, gastric healing rates with DA-5204 and DA-9601 were 42.1% (88/209) and 42.5% (90/212), respectively. The difference between the groups was −0.4% (95% confidence interval, −9.8% to 9.1%), which was above the non-inferiority margin of −14%. The cure rate of gastric erosion in both groups was 37.3%. The improvement rates of GI symptoms with DA-5204 and DA-9601 were 40.4% and 40.8%, respectively. There were no statistically significant differences between the two groups in both secondary endpoints. AEs were reported in 18 (8.4%) patients in the DA-5204 group and 19 (8.8%) in the DA-9601 group. Rates of AE were not different between the two groups. No serious AE or adverse drug reaction (ADR) occurred. These results demonstrate the non-inferiority of DA-5204 compared to DA-9601. DA-5204 is as effective as DA-9601 in the treatment of erosive gastritis. Registered randomized clinical trial at ClinicalTrials.gov (NCT02282670)</P>
( Myung Gyu Choi ),( Poong Lyul Rhee ),( Hyojin Park ),( Oh Young Lee ),( Kwang Jae Lee ),( Suck Chei Choi ),( Sang Young Seol ),( Hoon Jai Chun ),( Jong Sun Rew ),( Dong Ho Lee ),( Geun Am Song ),( H 대한소화기기능성질환·운동학회 2015 Journal of Neurogastroenterology and Motility (JNM Vol.21 No.3
Background/Aims: Therapies of functional dyspepsia (FD) are limited. DA-9701 is a novel prokinetic agent formulated with Pharbitis semen and Corydalis Tuber. We aimed to assess the efficacy of DA-9701 compared with itopride in FD patients. Methods: Patients with FD randomly received either itopride 50 mg or DA-9701 30 mg t.i.d after a 2-week baseline period. After 4 weeks of treatment, 2 primary efficacy endpoints were analyzed: the change from baseline in composite score of the 8 dyspeptic symptoms and the overall treatment effect. Impact on patients`` quality of life was assessed using the Nepean Dyspepsia Index (NDI) questionnaire. Results: We randomly assigned 464 patients with 455 having outcome data. The difference of the composite score change of the 8 symptoms between the 2 groups was 0.62, indicating that DA-9701 was not inferior to itopride. The overall treatment effect response rate was not different between the groups. When responder was defined as ≥ 5 of the 7 Likert scale, responder rates were 37% of DA-9701 and 36% of itopride group. Patients receiving DA-9701 experienced similar mean percentage of days with adequate relief during the 4-week treatment period compared with those receiving itopride (56.8% vs 59.1%). Both drugs increased the NDI score of 5 domains without any difference in change of the NDI score between the groups. The safety profile of both drugs was comparable. Conclusions: DA-9701 significantly improves symptoms in patients with FD. DA-9701 showed non-inferior efficacy to itopride with com - parable safety. (J Neurogastroenterol Motil 2015;21:414-422)
최훈규,오석전,정환영,김남규,김광명 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.10
본 교실에서 치험한 181예의 고혈압성 기저핵 출혈 환자를 대상으로 수술적 치료와 보존적 치료결과를 비교해 보면 전체적으로 보아서는 수술적 치료 방법이 보존적 치료보다 효과가 있다고 결론을 내리기는 어려우나 출혈양이 40ml이상이거나 CT상에서 혈종의 파금정도가 심한 경우에는 수술적 방법이 보존적 치료보다 결과가 우수하였고, 신경학적 장애 정도가 심한 환자에서 7시간 이내의 조기수술이 사망율을 낮출 수 있는 것으로 보인다. One-hundredand eighty one patients with hyertensive basal ganglia hemorrhage were followed at least 3 months after the ictus and there outcome was evaluated on the basis of activity of daily living and mortality. They were analysised according to neurological status on admission, the extension of hematoma, hematoma volume and the time span from ictus to operation. In general, out result failed to support the view that the surgical treatment is supperior to the conservative one in the management of hypertensive basal ganglia hemorrhage. However, this study showed some surgical advantage in case of hematoma above 40㎖, stupurous or semicomatous mentation. And the mortality was lower in early surgery growp(within 7 hrs) than other group.
Choi, Moon-Tae,Yun, Yeo-Uk,Lee, Jin-Il,Lee, Jong-Eun,Jung, Suck-Kee,Nam, Yun-Gyu,Lee, Young Han 한국토양비료학회 2014 한국토양비료학회지 Vol.47 No.4
The management of soil chemical properties is very important to sustainable agriculture of many horticultural crops, including cucumber. This study was conducted to find the optimal soil properties of environmentally friendly agriculture in controlled horticulture. Soil chemical properties of 267 samples were collected from soil in Chungnam Province. The average of pH, EC, OM, available $P_2O_5$, exchangeable K, Ca, and Mg was 6.1, $5.38dS\;m^{-1}$, $34g\;kg^{-1}$, $1,321mg\;kg^{-1}$, $1.50cmol_c\;kg{-1}$, $10.3cmol_c\;kg{-1}$, and $3.4cmol_c\;kg{-1}$, respectively. The organic matter content in silty clay loam was significantly higher than in the other soil textures, whereas the pH, EC, exchangeable K, and Mg in loamy fine sand showed significantly lower among soil textures. The EC value and exchangeable Mg concentration were highest in mountain foot-slope soils. The frequency distribution within optimum range of soil chemical properties was 26.2%, 30.3%, 2.3%, 3.8%, 3.4%, and 6.7% for pH, OM, available $P_2O_5$, exchangeable K, Ca, and Mg, respectively. Especially, excessive portion of available $P_2O_5$ and exchangeable Ca were 94.0% and 94.4%, respectively. The EC value and organic matter content of soil samples were positive correlation with all chemical properties except soil pH. In principle component analysis of chemical properties in soil samples, the percentage of variance explained by PC 1 was 52.2%, while PC 2 explained 21.3% of the variance, for a cumulative total of 73.5%. In conclusion, these results are considered to improve soil nutrient management for sustainable controlled horticulture.
최훈규,김광명,정환영,김남규,오석전,백광흠 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.10
A 3 years old boy had precocious puberty and hypothalamic hamartoma. CT scan and MRI disclosed an interpedunculary tumor. A craniotomy was sucessfully performed and grossly total removal of tumor was done. In the hormon study at postoperative 10 days. s-LH, s-FSH and s-testosterone were decreased. But, sexual precocity was not improved and s-testosterone level was increased over preoperative level.
한 대학병원 내과계중환자실에서 장기간 기계 환기를 받은 환자들의 3년 예후
전규락 ( Gyu Rak Chon ),최익수 ( Ik Su Choi ),임채만 ( Chae Man Lim ),고윤석 ( Youn Suck Koh ),오연목 ( Yeon Mok Oh ),심태선 ( Tae Sun Shim ),이상도 ( Sang Do Lee ),김우성 ( Woo Sung Kim ),김동순 ( Dong Soon Kim ),김원동 ( Won Don 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.62 No.5
연구배경: 내과계중환자실에서 72시간 이상 장기간 기계 환기를 받은 환자들의 자료가 부족하여 기저질환별, 기계 환기가 필요했던 원인질환별로 장기 예후를 관찰하며, 또한 1년째에는 삶의 질 평가를 같이 수행하여 이 환자들의 삶의 질 상태를 평가 하고자 하였다. 방법: 2003년 3월부터 2003년 7월까지 서울아산병원 내과계중환자실에서 72시간 이상 기계 환기치료를 받은 환자 73명을 대상으로 1, 3, 6, 12, 24, 36개월 생존율을 전향적으로 관찰하고 1년 생존자를 대상으로 Short Form 36(SF-36)을 이용하여 삶의 질을 측정하였다. 결과: 대상 환자들의 1개월 생존율은 54.8%(40/73), 3개월 생존율은 39.7%(29/73), 6개월 생존율은 30.1% (22/73), 12개월 생존율은 20.5%(15/73), 24개월 생존율은 18.3%(13/71), 그리고 36개월 생존율은 16.9% (12/71)이었다. 3년간 생존율은 기계 환기가 필요했던 원인질환별로는 차이가 없었고, 기저질환별로는 신생물 또는 만성간질환이 만성폐질환이나 만성신장질환에 비해 예후가 불량하였다(p<0.05). SF-36을 이용한 삶의 질 평가에서 정상 대조군과 비교 시 정신적 건강영역에서 Role limiting due to emotional problem을 제외하고 모두 낮은 값을 보였다. 결론: 한 대학병원 내과계중환자실에서 72시간 이상 장기간 기계 환기를 받은 환자들의 3년간 생존율은 낮았으며, 12개월까지 지속적으로 낮아지나 12개월부터 36개월까지는 유지되었다. 1년 시점에서 삶의 질 평가 시 이 환자들의 삶의 질 상태가 낮음을 보여주었다. Background: There is little data on the 3 year prognosis and quality of life of patients on long-term (>72 hour) mechanical ventilation in a medical intensive care unit (MICU). Methods: Patients with long-term mechanical ventilation from May 2003 through July 2003 in MICU of Asan Medical Center, Seoul were enrolled in this studay. The survival rates were observed prospectively at 1, 3, 6, 12, 24, 36 months, and the quality of life of survivor was measured at 12 months by using Short Form 36 (SF-36). Results: The survival rate at 1, 3, 6, 12, 24 and 36 months was 54.8% (40/73), 39.7% (29/73), 30.1% (22/73), 20.5% (15/73), 18.3% (13/71) and 16.9% (12/71), respectively. There was a similar survival rate regardless of the diseases that required mechanical ventilation. A neoplasm or chronic liver disease had a worse survival rate than chronic lung or kidney disease (p<0.05). Each SF-36 domain except for the Role-emotional was inferior to the general population. Conclusions: The survival rate of patients with mechanical ventilation more than 72 hours is decreases continuously until 12 months but is relatively constant from 12 to 36 months. In these patients quality of life is also decrased. (Tuberc Respir Dis 2007; 62: 398-405)
한국인의 온열쾌적감 및 생리신호에 관한 연구 -Part 3: 상하온도차에 관한 실험 결과
김동규 ( Dong Gyu Kim ),배동석 ( Dong Suck Bae ),금종수 ( Jong Soo Kum ),최광환 ( Kwang Hwan Choi ),김성일 ( Sung Il Kim ),임금식 ( Keum Sik Im ),이구형 ( Koo Hyoung Lee ) 한국감성과학회 1998 춘계학술대회 Vol.1998 No.-
본 연구의 목적은 겨울철 난방시 한국인의 온열감각과 온열환경지표 사이의 상관관계 및 ASHRAE Standard 55-74의 쾌적영역과 한국인의 쾌적영역을 체감실험을 통해 규명 및 제시하는 것이다. 유니폼을 착용한 피실험자는 온도, 습도, 기류 등이 조절되는 환경시험실에서 2시간동안 체재하면서 매 15분 마다 전신온냉감, 쾌불쾌감 등을 신고하였다. 또한 인체의 3부위에서 피부온도, 환경시험실의 온도 및 습도를 매 20초 간격으로 측정하였다. 이상의 체감실험을 통해 아래의 결론을 얻었다. 1)평균피부온도가 증가함에 따라 TSV는 선형적으로 증가하며 열적으로 중립감을 느낄 때의 평균피부온도는 청년 34.0℃, 고령자 33.5°C이다. 2)TSV=0일때 청년의 중립 SET*는 25.5°C, 고령자의 중립 SET*는 27.0℃이다. 3)한국인의 쾌적범위는 청년의 경우 SET*의 경우 24.2-26.8°C, 고령자의 경우 SET*25.7-28.2°C로 ASHRAE St.55-74의 권장 쾌적범위 (22.0-25.4°C)보다 다소 고온지향적이다.
Moon-Tae Choi,Yeo-Uk Yun,Jin-Il Lee,Jong-Eun Lee,Suck-Kee Jung,Yun-Gyu Nam,Young Han Lee 한국토양비료학회 2014 한국토양비료학회지 Vol.47 No.4
The management of soil chemical properties is very important to sustainable agriculture of many horticultural crops, including cucumber. This study was conducted to find the optimal soil properties of environmentally friendly agriculture in controlled horticulture. Soil chemical properties of 267 samples were collected from soil in Chungnam Province. The average of pH, EC, OM, available P₂O?, exchangeable K, Ca, and Mg was 6.1, 5.38 dS m<SUP>-1</SUP>, 34 g kg<SUP>-1</SUP>, 1,321 mg kg<SUP>-1</SUP>, 1.50 cmolc kg<SUP>-1</SUP>, 10.3 cmolc kg<SUP>-1</SUP>, and 3.4 cmolc kg<SUP>-1</SUP>, respectively. The organic matter content in silty clay loam was significantly higher than in the other soil textures, whereas the pH, EC, exchangeable K, and Mg in loamy fine sand showed significantly lower among soil textures. The EC value and exchangeable Mg concentration were highest in mountain foot-slope soils. The frequency distribution within optimum range of soil chemical properties was 26.2%, 30.3%, 2.3%, 3.8%, 3.4%, and 6.7% for pH, OM, available P₂O?, exchangeable K, Ca, and Mg, respectively. Especially, excessive portion of available P₂O? and exchangeable Ca were 94.0% and 94.4%, respectively. The EC value and organic matter content of soil samples were positive correlation with all chemical properties except soil pH. In principle component analysis of chemical properties in soil samples, the percentage of variance explained by PC 1 was 52.2%, while PC 2 explained 21.3% of the variance, for a cumulative total of 73.5%. In conclusion, these results are considered to improve soil nutrient management for sustainable controlled horticulture.
한국인의 온열쾌적감 및 생리신호에 관한 연구 Part IV: 대류난방시 Draft가 온열쾌적감에 미치는 영향
김동규 ( Dong Gyu Kim ),최호선 ( Ho Seon Choi ),이기섭 ( Gi Seop Lee ),금종수 ( Jong Soo Kum ),최광환 ( Kwang Hwan Choi ),배동석 ( Dong Suck Bae ),이구형 ( Koo Hyoung Lee ) 한국감성과학회 1998 추계학술대회 Vol.1998 No.-
난방·공조공간에서는 강한 기류가 Draft를 유발한다. Draft라 함은 인체가 기류(Air Movement)에 의해 원하지 않은 국부적인 냉각효과를 받는 것을 말한다(ASHRAE). 본 연구에서는 피험자의 체감실험을 통해 겨울철 대류난방시 실온 설정조건에 대한 기류속도의 허용범위을 찾고자 하였다. 피험자는 일정 유니폼을 착용하고 의자에 앉은 상태로 실온 18·21·24℃, 풍속 0.15·0.3·0.45m/s의 조건에서 기류감, 온냉감, 쾌불쾌감을 신고하였다. 실험시 착의량은 남자 0.7, 여자 1.0 clo이었으며, 실온이 21℃일 때는 기류속도 0.15m/s까지, 실온이 24℃일 때는 기류속도 0.3m/s까지 허용범위에 포함되었다.