尿流力學檢査의 意義

金光明,朱槿源 최신의학사 1982 最新醫學 Vol.25 No.8

선택적 파킨슨씨병 백서의 흑질내 도파민성 신경세포의 형태적 변화

김광명,김영수 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.1

The great majority of studies on tissue implantation in Parkinson's rat models have been performed. Recently the new rat model which is similar to clinical Parkinson's disease was developed. The characteristic feature of this model had the remaining dopaminergic neurons in substantia nigra (SN) after injection of 6-hydroxydopamine(6-OHDA). The investigators reported that the model was appropriate to studying the recently reported phenomenon of sprouting from host dopaminergic neurons following tissue implantation. But there has been no morphologic study of degeneration of dopaminergic neurons after the injection of the toxin. Authors investigated the changes of the dopaminergic neurons in SN of selectively lesioned Parkinson's rat model. Acute changes of dopaminergic neurons in SN after injection of 6-OHDA. were pyknosis, decreased number and destruction of neurons, and surrounding edema Neurons distal to injection site were progressively destroyed and degenerated, and their nerve fibers were injured also. In chronic state, the number of dopaminergic neurons in right lesioned SN was decreased, and about 10.2% of number of intact Ieft SN. In right SN, glial cells were increased, scar reactions were noticed, and large sized neuron was not visualized. Nerve fibers and neuronal processes of remaining neurons were destroyed and their shape was irregular and their TH-lR reaction were decreased.

부동산경매기초이론

김광명 명지대학교 증권보험대학원 2000 논문집 Vol.- No.4

인삼 추출액이 고양이의 뇌압 및 혈압에 미치는 영향

김광명,정환영 대한신경외과학회 1976 Journal of Korean neurosurgical society Vol.5 No.1

There are two contradictive opinions of the therapeutic administration of Ginseng in the conditions of cerebrovascular accident and/or hypertensive heart diseases. This experimental study was performed to observe the effects of the Ginseng extract on the blood pressure (BP) and intracranial pressure (ICP) at the same time. Seven mongrel cats were used. ICP was measured with epidural balloon and pressure transducer, and BP with intraarterial catheter via femoral route. Both were continuously recorded by polygrapher. 1. In a normal condition, a single intravenous injection of Ginseng 100mg/kg induced immediate reduction of BP for 30∼45 second. Intracranial pressure, however, showed delayed elevation for 50∼60 second. 2. Even in a condition of increased ICP or induced cardiac hypertension, the results were the same as in above-described normal condition.

난소적출후 유발된 흰쥐의 골다공증에서 Estradiol의 효과에 관한 소주골의 형태계측학적 연구

김광명,이명철,성상철,박상철,송계용 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.1

Postmenopausal osteoporosis is known to be related to estrogen deficiency and give rise to spine and hip fracture in old person. The purpose of this expreimental study is to investigate whether or not the replacement estrogen administration could improve the process of esblished osteoporosis induced by bilateral oophorectomy in rats. Sprague-Dawley rats, aged five months, were seperated into two groups, group 1 was the control group that had oophorectomy alone without estradiol treatment. Group 2 was the experimental group, in which estradiol adminitration started at fourth week after oophorectomy. Five rats were killed weekly until the eighth week after oophorectomy. For each group, both tibia, lumbar vertebra & ilium were harvested. Histological analysis and histomorphometric measurements of trabecular bone area of proximal tibia, ilium & lumbar vertebra(L_6) were done by quantitative image analysis system. Following results were observed : Histological study revealed mild to moderate loss of trabecular bone area at the 5th week after bilateral oophorectomy followed by more advanced osteoporosis at 7th to 8th week. These osteoporotic changes were delayed and improved by estradiol therapy after 3rd to 4th week of treatment. Similar tendency of these effects were noted also in lumbar vertebra, ilium and upper tibia. Histopathology of the bone revealed that bone loss induced by bilateral oophoretomy occurred mainly in the trabecular bone. Histomorphometric analysis also revealed that mild to moderate decrease of the trabecular bone areas after bilaterial oophorectomy with estradiol treatment were noted in lumbar vertebra, ilium and tibia. Based on this short term therapy, estradiol treatment appeared to improve the osteoporosis either by partially restoring the trabecular bone mass or delaying the progression the osteoporotic process in rat.

Trasylol 및 Dexamethasone 이 토끼의 지주막하 출혈후에 오는 뇌수종 발생에 미치는 영향

김광명 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

Hydrocephalus was reported to occur in man in approximately 35% of subarachnoid hemorrhage add shunting procedure was inevitable in about one third of them. This study was planned to explore the possibility of preventing the evolution of hydrocephalus after subarachnoid hemorrhage by Trasylol or dextmathasone therapy. A total of eighty-seven rabbits weighing 3㎏ were used. Three times of cisternal injections of 0.15ml of blood were performed at every other day. Seventeen rabbits died of initial technical failure at the time of the first cisternal injection of blood. The remaining seventy rabbits were divided into four groups; Group Ⅰ (20 rabbits) was of control group, Group Ⅱ (10 rabbits) received three cisternal injection of 5,000 KIU of Trasylol at the time of cisternal blood injection, Group Ⅲ (20 rabbits) received intravenous injection of 2,000 KIU of Trasylol four times daily for 10 days, and Group Ⅳ (20 rabbits) was treated with intramuscular injection of dexamethasone which was gradually tapered for 10 days. All the rabbits were sacrified three weeks later the last cisternal injection of blood. Their heads were sectioned and ventricular measurement was made. Trasylol and dexamethasone reduced the incidence of hydrocephalus from 31% to 43% while 81% in control group. The mortality rate after subarachnoid hemorrhage was also remarkably reduced in the treated groups. A reduction in post-SAH hydrocephalus can be achieved by Trasylol and dexamethasone. It seems to be by their anti-inflammatory effects.

自然科 學習의 行動目標 設定에 關한 硏究 : 變化槪念 單元을 中心으로 Especially in the Units of the Concepts of Chnge

金光明 춘천교육대학교 과학교육연구소 1982 과학교육연구 Vol.8 No.-

효과적인 과학 학습지도 방안에 관한 연구 : 국민학교 자연과 학습을 중심으로

김광명 춘천교육대학교 초등교육연구소 1987 敎育硏究 Vol.5 No.-

There are some problems is school science teaching in korea, on the aspect of inquiry learning. It was thought that science teaching strateges are inadequate which cause the poor achivement of inquiry learning. The teaching strateges of various aspects of researchers are deseribed and compared. And the most effective science teaching strateges in elementary schoole are sought. It was recommended that the Learning Cycle of Descriptive type and Empirical-Inductive one are most effective science teaching strategies in elementary school.

古代韓國의陪墓 - 嶺南地域을中心으로

김광명,정은정 한국문화유산협회 2009 야외고고학 Vol.0 No.6

陪墓는 일반적으로‘한 무덤 옆에 딸린 무덤’으로 정의되고 있다. 우리나라에서 배묘가 발생하는 시기는 청동기시대부터인 것으로 추정된다. 배묘는 자체적인 주검보호시설을 갖추고 있다는 점에서 殉葬(墓)과 차별화 된다. 청동기시대의 배묘는 주로 지석묘 주변에서 확인되며, 1기에서 3~4기까지 다양한 배치형태를 가지며 나타난다. 이후 木棺墓段階에서는 배묘의 존재를 찾을 수 없고, 木槨墓段階에 이르러서야 배묘는 다시 역사의 전면에 등장하게 된다. 이때의 배묘는 목곽묘(主墓) 주변에서 주로 甕棺의 형태로 축조된다. 石槨墓(高塚)段階의 배묘는 주로 고총이나 대형 석곽묘의 봉토내에 혹은 호석열 주변, 또는 호석열에 잇대어 배치되기도 한다. 이때 배묘는 石槨, 橫口式石槨, 石槨甕棺, 甕棺등 다양한 형태로 만들어진다. 石室墓段階는 석곽묘단계와 유사한 배치양상을 보이며, 배묘의 형태는 석곽옹관, 옹관 등으로 축조된다. 삼국시대의 배묘는 新 와 伽倻지역이 많은 차이점을 보이고 있다. 이와 같이 단위지역 배묘의 형태가 다르게 나타난다는 점은 당시 시기별로, 지역별로 다양한 장례문화가 존재했음을 의미한다. 또한 배묘는 그 외형적인 면에 있어 主墓와 전혀 다를 바 없고, 부장유물도 역시 마찬가지이다. 그리고 순장과 달리 자체적인 매장주체시설을 갖추고 있다는 점, 위신재 등의 유물을 다수 부장하고 있다는 점에서 배묘의 피장자는 순장자보다는 높은 위계를 지닌 사람으로 볼 수 있다. 즉 배묘의 피장자는 당시 한 집단의 최상위계층 또는 차상위계층에 해당하는 지위를 가진 자들이거나 혹은 이런 사람들과 혈연적 또는 정치·사회적으로 밀접한 관계를 가진 사람들로 생각된다. 따라서 우리는 배묘의 존재를 통해 당시 사회구조의 일면을 이해할 수도 있을 것이다. A subordinate tomb is usually defined as 'a tomb attached to another tomb'. In the Korean peninsula, subordinate tombs are thought to have emerged in the Bronze Age. Subordinate tombs differ from sunjang (sacrificial) burials in that they had separate compartments used to protect the deceased. In the Bronze Age, subordinate tombs are found around dolmens and vary in the nature of their composition (subordinate tombs can number from one to up to three or four). Subordinate tombs are not found with wooden coffin tombs, and re-appear with the use of wooden outer cist tombs. In this case, subordinate tombs consist of jar coffins which are located around the wooden outer cist. Subordinate tombs of the stone lined tomb period consist of other stone lined tombs which can be located within the earthen mound of the central burial, or around or attached to the surrounding stone circle. Subordinate tombs of this period appear in various forms, such as the stone lined burial, stone lined burial with horizontal entrance, stone lined jar coffin burial, and jar coffin burial. The layout of subordinate tombs is similar in the stone chamber tomb period, with stone lined jar coffin burials and jar coffin burials used as subordinate tombs. The subordinate tombs of Silla and Gaya in the Three Kingdoms period differ significantly. These differences, which exist on a large scale, indicate the presence of temporal and spatial variation in terms of burial practices. Subordinate tombs and central tombs show similarities in terms of external appearance, as well as grave goods. In addition, the fact that subordinate tombs have their own burial compartments, unlike sacrificial burials, and contain prestige objects, illustrates that the deceased was of higher rank than those buried in sacrificial burials. It therefore appears that the deceased of subordinate tombs consisted of individuals of the highest or second highest rank or those closely related to them in terms of blood or political and social ties. Consequently, the presence of subordinate tombs may give us insight into the nature of past social structure.

날씨 변화 觀察의 問題點

金光明 춘천교육대학교 과학교육연구소 1980 과학교육연구 Vol.7 No.-

Many difficulties were found in observing weather in the unit of ‘Weather change’ in elementary school science curriculum. More effective observing method could be suggested as follows; 1)Cloud cover should be estimated as the number of fourths of the sky covered by clouds. 2)The simple rainguage should be made into smaller vessel than the rain collecting one, which could measure the amount of rain by enlarged scale. 3)Wind speed should be measured by three grade. 4)It is hard to measure the daily cycle of temperature, so daily average temperature should be measured over a long period.