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      • SCOPUSKCI등재

        Nutcracker 증후군 1예

        김광명,박영서,김인원,고광욱,최용,정해일,진동규,최황,이창연,연경모 대한신장학회 1989 Kidney Research and Clinical Practice Vol.8 No.1

        The nutcracker syndrome refers to the compression of the left renal vein between aorta and superior mesenteric artery which results in hematuria, at times associated with flank pain, abdominal pain or varicocele. We report a girl with this syndrome presenting with persistent gross hematuria for 2 months. Urine erythrocytes showed only 1% of dysmorphism, and ultrasonography revealed compression of left renal vein between arota and superior mesenteric artery, and left sided unilateral bleeding was confirmed by cystoscopy. Intraarterial digital subtraction angiography revealed compression of left renal vein and collateral circulation to left gonadal vein. The pullback pressure tracing from left renal vein to inferior vena cava showed pressure gradient of 3 mmHg between left renal vein and inferior vena cava. Ultrasonography and intraarterial digital subtraction angiography revealed the compression of the left renal vein between the aorta and superior mesenteric artery and regurgitation of the gonadal vein. The nutcracker syndrome should be considered as one of the causes of nonglomerular hematuria.

      • SCOPUSKCI등재

        간성(間性)에 관한 임상적(臨床的) 고찰(考察)

        김광명,김경도,이희영,Kim, Kwang-Myoung,Kim, Kyung-Do,Lee, Hee-Yong 대한생식의학회 1982 Clinical and Experimental Reproductive Medicine Vol.9 No.1

        We collected a total of 109 patients with intersex during the past 16 years (1966-1982). They were summerized as follows: Klinefelter's syndrome, the most common disease, was found in 76 cases, Turner's syndrome in 3 cases, true hermaphroditism in 5 cases, male pseudohermaphroditism in 5 cases, female pseudohermaphroditism in 13 cases and others in 7 cases in which 2 cases of XX male syndrome, 1 case of agonadism, 1 case of hernia uteri inguinale and 3 cases of unclassified intersex were included. 2 mosaic Klinefelter's syndrome showed 46/47 XX/XXY and 1 mosaic Turner's syndrome showed 45/46 XO/XX. The 5 patients with true hermaphroditism included 2 cases that had an ovary on one side and a testis on the other, 1 case, seperate ovary and testis on each side, 1 case, an ovary on one side and a seperate testis and ovary on the other and 1 case, an ovary on one side and an ovotestis on the other. Sex chromosome study on the true hermaphroditism revealed 46 XX in 2 patients and 46/46 XX/XY mosaicism in 3 patients. In male pseudohermaphroditism, all patients had a short and blind vagina. Of which, familial tendency was found in 1 case. Her sister had operation for sex reversal for female. In female psedohermaphroditism, all the patients were adrenogenital syndrome. Operations for clitoridectomy and vaginoplasty were performed on 10 patients. Hydrocortisone was given to 6 patients. Menstruation started to occur 6 months and 4 months after the medical therapy respectively in 2 cases.

      • KCI등재

        New Top Coating System of Chemically Anchored Phospholipid Monolayer on the Drug-encapsulated Polymer Film for Drug-Eluting Stent

        김광명,박상진,변영로,문현태 한국고분자학회 2010 Macromolecular Research Vol.18 No.5

        We report a novel method for preparing multi-layer polymer films as a matrix for local drug delivery that can be used as a drug-eluting stent. The base polymer matrix was an acrylated polymer film (poly(octadecyl acrylateco-hydroxybutyl acrylate, poly(OA-co-HA)), where echinomycin (EM) was dispersed into the poly(OA-co-HA)matrix. The top coating layer consisted of a chemically grafted phospholipid polymeric monolayer (polyPC) onto the acrylated polymer film. The chemically grafted phospholipid monolayer was prepared using in situ photopolymerization of a pre-assembled acrylated phospholipid (1-stearoyl-2-[12-(acryloyloxy)-dodecanoyl]-sn-glycero-3-phosphocholine) monolayer, produced by lipid vesicle fusion, onto the acrylated polymer film. Physiochemical characterization of the drug-encapsulated multi-layer polymer films was performed using scanning electron microscopy (SEM), water contact angle measurements and X-ray photon spectroscopy (XPS). Compared to the bare acrylated polymer film, the chemically grafted phospholipid monolayer over the acrylated polymer film showed significant changes in both the surface chemistry and drug release pattern. This phospholipid modified multi-layer polymer system was capable of reducing the burst release of the drug. In addition, it inhibited platelet adhesion and smooth muscle cell proliferation, in vitro, due to the highly dense phospholipid monolayer.

      • KCI등재
      • KCI등재

        온라인 P2P 환경에서 딥러닝을 적용한 다분류 기반 개인신용등급 예측모형

        김은미,박지영 한국인터넷전자상거래학회 2019 인터넷전자상거래연구 Vol.19 No.4

        In this study, we propose a multi–class personal credit rating prediction model applying deep learning to accurately predict personal credit rating as a way to reduce investor's investment risk. In P2P lending, credit information on borrowers has an important influence on investment decisions, since investors make investment decisions based on objective information of borrowers without special collateral. To develop the multi-class prediction model, we use the Lending Club loan data to classify the customer's grade into four classes, and randomly extract 1,000 data from each grade and use a total of 4,000 data. We apply the method which is MDA, ANN, one-against-one, Weston and Watkins, Crammer and Singer, and DNN. The MDA and ANN were used as benchmarking models. As the results, DNN shows higher prediction performance than other models, so that deep learning can be applied with excellent performance in multi-class problems. In addition, the confusion matrix shows that the DNN model can reduce the investment risk of investors rather than the multi-class SVM model. By applying the DNN, we can make up for the defect of the multi-class SVM, which is obtained through multiple binary classifications, and can be applied more efficiently in big data environment. The proposed method can protect investors from investment risk by providing more detailed information on investment decisions in online P2P finance.

      • 자연에 대한 미적 인식과 환경미학

        김광명,Kim, Kwang-Myung 한국조형예술학회 2008 조형예술학연구 Vol.13 No.-

        It seems to be difficult to bridge between human and nature. All depictions of nature are not necessarily reflections of reality. Thoughts are projected into nature, then nature will reflect us. The world is composed of natural and cultural environment. There are differences between depiction of nature based on correspondence and construction of world. Environmental aesthetics is an emerging field of study that focuses on nature's aesthetic value as well as on its ethical and environmental implications. Allen Carlson, a pioneer in environmental aesthetics, provides challenges as well as a wealth of resources for those who would appropriate his ideas in the service of environmental protection. Carlson's positive aesthetics, his focus on the functionality of human environments, and his integration of aesthetics and ethics have great import for those seeking to use aesthetics to assist in addressing environmental controversies. Environmental ethics would benefit from taking environmental aesthetics more seriously. Environmental aesthetics is an emerging discipline that explores the meaning and influence of environmental perception and experience on human life. Arguing for the idea that environment is not merely a setting for people but fully integrated and continuous with us, Arnold Berleant explores the aesthetic dimensions of the human-environment continuum in both theoretical terms and concrete situations. Aesthetic experience is always contextual. The aesthetic aspect of any human habitat is an essential part of its desirability. The aesthetic perception of environment shows us the reciprocity that constitutes both person and place. The genuine beauty lies in the coexistence and harmony with natural environment.

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