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      • KCI등재

        Structural, magnetic and optical properties of diluted magnetic semiconductor (DMS) phase of Ni modified CuO nanoparticles

        Kumar Arvind,Kumar Manish,Chandra Sati Prakash,Srivastava Manish Kumar,Ghosh Surajit,Kumar Shiv 한국물리학회 2021 Current Applied Physics Vol.32 No.-

        Control on the size of copper oxide (CuO) in the nano range is a highly motivating approach to study its multifunctional nature. The present investigation reports a sol-gel derived Ni doped CuO nanoparticles (Cu1- xNixO). Rietveld refinement of the XRD spectra confirms the formation of single monoclinic phase of Cu1-xNixO nanoparticles having crystallite size within the range of 19–21 nm. Raman spectra show the presence of characteristics Raman active modes and vibrational bands in the Cu1-xNixO samples that corroborate the monoclinic phase of the samples as revealed by refinement of XRD data. The estimated band gap of pure CuO is found to be ~1.43 eV, which decreases with the increase of dopant concentration into CuO matrix. This result is in line with estimated crystallite size. Magnetization curves confirm the weak ferromagnetic nature of Cu1-xNixO nanoparticles which reveal the DMS phase. This weak magnetic nature may be induced in the samples due to the exchange interaction between the localized magnetic d-spins of Ni ions and carriers (holes or electrons) from the valence band of pristine CuO lattice. Replacement of Cu+2 by Ni+2 ions into the host CuO lattice induces the magnetization. The quantified value of squareness ratio (S < 0.5) confirms the inter-grain magnetic interactions in the Cu1-xNixO nanoparticles which is also the reason of weak induced magnetization.

      • Development of a Unique Mouse Intervertebral Disc Degeneration Model Using a Simple Novel Tool

        Baldia Manish,Mani Sunithi,Walter Noel,Kumar Sanjay,Srivastava Alok,Prabhu Krishna 대한척추외과학회 2021 Asian Spine Journal Vol.15 No.4

        Study Design: Animal case control study.Purpose: To create a simple, reproducible disc degeneration model for mouse coccygeal vertebrae. Overview of Literature: Back pain due to disc degeneration is probably the most common problem encountered in neurosurgical practice. An easily reproducible animal model for disc degeneration will help in understanding its pathophysiology, and serve as a platform for examining various therapeutic options.Methods: A total of 18 mice were divided into injured (n=12) and non-injured (n=6) groups. The disc height index (DHI%) at coccygeal 4–5 level was measured by computed tomography (CT) scan for all mice. Coccygeal 4–5 discs of the injury group were injured using a 32G needle fixed to a novel tool and confirmed by CT. The non-injury group underwent no procedure. DHI% was measured by CT at 2-, 4-, and 6-week post-injury, and all mice tails were sectioned for histopathology grading of disc degeneration at the respective time intervals.Results: The injured group showed significant variation in DHI% at 2, 4, and 6 weeks, whereas there was no change in the noninjured group. Histopathologic evaluation with Safranin O stain showed a worsening of the disc degeneration score at 2, 4, and 6 weeks in the injured group, but in the non-injured group there was no change. Percutaneous needle injury technique with our novel tool provided 100% accuracy and uniform degeneration.Conclusions: A simple, easily reproducible mouse model for disc degeneration was created using a simple, cost-effective, novel tool and technique, its advantage being high precision and user friendly.

      • KCI등재

        Recent Advances for Fabricating Smart Electromagnetic Interference Shielding Textile: A Comprehensive Review

        Sarika Verma,Manish Dhangar,Sriparna Paul,Kamna Chaturvedi,Mohammed Akram Khan,Avanish Kumar Srivastava 대한금속·재료학회 2022 ELECTRONIC MATERIALS LETTERS Vol.18 No.4

        A sharp elevation in the generation of electromagnetic interference (EMI) is observed, directly proportional to the increasein digital and electronic appliances. With the high growing population and enhancement in the number of electrical devicesused in personal, industrial and medical sites, the issues arising due to EMI are also at their peak. EM wave interference isknown to cause malfunctioning of the nearby electronic devices, destroying the signals and affecting human health, causingnausea, headaches, neural deformities etc. To avoid the harmful effect of these interferences, the personnel in its vicinity needa shielding material, protecting them from the ill effects of the electromagnetic waves. In this review article, EMI shieldingtextiles are being focused upon. Cotton, spandex, PET, PAN, silk fabric, etc., are modified through various methods andtechniques like drop-casting, layer-by-layer electrostatic self-assembly, click chemistry, and inkjet printing to perform thefunction of shielding of EM waves. These smart, flexible, hydrophobic and light weighing fabrics can be revolutionary indiminishing the deteriorating effects of EM waves in the human body. Surface modified having high electrical conductivitiesand EMI SE of up to and beyond 90 dB in various frequency ranges have been reported, providing promising and alternativepersonal protective equipment for electromagnetic interference shielding.

      • KCI등재

        COVID-19 Rapid Antigen Test: Role in Screening Prior to Gastrointestinal Endoscopy

        Ashok Dalal,Ujjwal Sonika,Manish Kumar,Roshan George,Ajay Kumar,Siddharth Srivastava,Sanjeev Sachdeva,Barjesh Chander Sharma 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.4

        Background/Aims: The severe acute respiratory syndrome coronavirus 2 pandemic has affected the gastrointestinal (GI) endoscopyunits globally owing to the risk of transmission. We present our data on the use of rapid antigen test (RAT) as a screening tool priorto endoscopy to prevent the transmission of coronavirus disease (COVID-19). Methods: This study was a retrospective analysis of patients who underwent any GI endoscopic procedure from July 2020 to October2020 at a tertiary referral center in New Delhi, India. All patients underwent screening for COVID-19 using RAT, and endoscopywas performed only when the RAT was negative. The data are presented as numbers and percentages. Results: A total of 3,002 endoscopic procedures were performed during the study period. Only one endoscopic procedure wasperformed in a COVID-19 positive patient. A total of 53 healthcare workers were involved in conducting these procedures. Only2 healthcare workers (3.8%) were diagnosed COVID-19 positive, presumably due to community-acquired infection, during thisperiod. Conclusions: The COVID-19 RAT is easily usable as a simple screening tool prior to GI endoscopy during the COVID-19 pandemic.

      • KCI등재

        RWON Study: The Real-World Walled-off Necrosis Study

        Ankush Pawar,Ujjwal Sonika,Manish Kumar,Sundeep Saluja,Siddharth Srivastava 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.6

        Background/Aims: The management of walled-off necrosis (WON) has undergone a paradigm shift from surgical to nonsurgicalmodalities. Real-world data on the management of symptomatic WON are scarce. Methods: Prospectively collected data of symptomatic WON cases were retrospectively evaluated. The treatment modalities usedwere medical management alone, percutaneous catheter drainage (PCD) or endoscopic drainage (ED), or a combination of PCD andED. We compared clinical outcome among these modalities. Results: A total of 264 patients were evaluated. The most common indications for drainage were pain and fever. Of the patients,28% was treated with medical therapy alone, 31% with ED, 37% with PCD, and 4% with a combined approach. Technical successand clinical success were achieved in 93% and 91% of patients in the endoscopic arm and in 90% and 81% patients in the PCD arm,respectively (p=0.0004 for clinical success). Lower rates of complications (7% vs. 22%, p=0.005), readmission (20% vs. 34%, p=0.04),and mortality (4% vs. 19%, p=0.0012), and shorter hospital stay (13 days vs. 19 days, p=0.0018) were observed in the endoscopicgroup than in the PCD group. Conclusions: ED of WON is better than PCD and is associated with lower mortality, fewer complications, and shorter hospitalization.

      • KCI등재

        Genetic diversity and population structure assessment of Hellenia speciosa from Indian agro-ecological regions using inter-simple sequence repeat markers

        Prabhu Kamasamudra N.,Rodrigues Vereena,Kumar Amit,Kumar Manish,Srivastava Sharad,Shukla Ashutosh K.,Sundaresan Velusamy 한국원예학회 2023 Horticulture, Environment, and Biotechnology Vol.64 No.2

        Hellenia speciosa (J. Koenig) S. R. Dutta (Syn: Costus speciosus (J. Koenig) Sm.) is well known for its anti-diabetic proper- ties and is in high demand for its steroidal sapogenin, diosgenin, which is used in the pharmaceutical industry for manufac- turing steroidal drugs. The increasing demand for this plant has led to the depletion of its wild population. This study was conducted to reveal the genetic diversity of H. speciosa collected from various agro-ecological regions of India for use in devising conservational strategies, and cultivation and breeding programs. Twenty inter-simple sequence repeat markers yielded 304 products with 100% polymorphism demonstrating high genetic diversity. Nei′s gene diversity and Shannon information indexes were estimated among the populations as 0.19 ± 0.23 and 0.28 ± 0.25, respectively. High genetic dif- ferentiation ( GST = 0.40) and low gene fl ow ( Nm = 0.74) were observed, which corroborated with the analysis of molecular variance revealing maximum (86.75%) variance within populations. The unweighted pair group method with arithmetic mean analysis grouped all accessions into three major clusters. Principal component analysis showed that the fi rst three compo- nents accounted for 30.66%, 4.54%, and 3.98% variation, respectively, and Bayesian clustering through structure showed the presence of two genetic population (K = 2). This study revealed high genetic diversity among the populations collected from high altitude compared to those from the plain. A positive but low correlation among genetic and geographic distances was obtained ( r = 0.282, p < 0.0001). Identifi cation of genetic diversity and intra population variation of a species are prime factors to take defi ned conservation strategies.

      • Microwave-Assisted Synthesis of Boron and Nitrogen co-doped Reduced Graphene Oxide for the Protection of Electromagnetic Radiation in Ku-Band

        Umrao, Sima,Gupta, Tejendra K.,Kumar, Shiv,Singh, Vijay K.,Sultania, Manish K.,Jung, Jung Hwan,Oh, Il-Kwon,Srivastava, Anchal American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.35

        <P>The electromagnetic interference (EMI) shielding of reduced graphene oxide (MRG), B-doped MRG (BMRG), N-doped MRG (N-MRG), and B-N co-doped MRG (B-N-MRG) have been studied in the Ku-band frequency range (12.8-18 GHz). We have developed a green, fast, and cost-effective microwave assisted route for synthesis of doped MRG. B-N-MRG shows high electrical conductivity in comparison to MRG, B-MRG and N-MRG, which results better electromagnetic interference (EMI) shielding ability. The co-doping of B and N significantly enhances the electrical conductivity of MRG from 21.4 to 124.4 Sm-1 because N introduces electrons and B provides holes in the system and may form a nanojunction inside the material. Their temperature-dependent electrical conductivity follows 2D-variable range hopping (2D-VRH) and Efros-Shldovskii-VRH (ES-VRH) conduction model in a low temperature range (T < 50 K). The spatial configuration of MRG after doping of B and N enhances the space charge polarization, natural resonance, dielectric polarization, and trapping of EM waves by internal reflection leading to a high EMI shielding of -42 dB (-99.99% attenuation) compared to undoped MR.G (-28 dB) at a critical thickness of 1.2 mm. Results suggest that the B-N-MRG has great potential as a candidate for a new type of EMI shielding material useful in aircraft, defense industries, communication systems, and stealth technology.</P>

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