Experience of Subjective Symptoms in Euthymic Patients with Bipolar Disorder

Soohyun Joe,Yeonho Joo,Seongyoon Kim 대한의학회 2008 Journal of Korean medical science Vol.23 No.1

Bipolar patients often experience subjective symptoms even if they do not have active psychotic symptoms in their euthymic state. Most studies about subjective symptoms are conducted in schizophrenia, and there are few studies involving bipolar patients. We examined the nature of the subjective symptoms of bipolar patients in their euthymic state, and we also compared it to that of schizophrenia and normal control. Thirty bipolar patients, 25 patients with schizophrenia, and 21 normal control subjects were included. Subjective symptoms were assessed using the Korean version of the Frankfurter Beschwerde Fragebogen (K-FBF) and the Symptom Check List 90-R (SCL90-R). Euthymic state was confirmed by assessing objective psychopathology with the Positive and Negative Syndrome scale of Schizophrenia (PANSS), the Young Mania Rating Scale (YMRS), and the Montgomery Asberg Depression Rating Scale (MADRS). K-FBF score was significantly higher in bipolar patients than in normal controls, but similar to that in schizophrenia patients (F=5.86, p=0.004, R2=2033.6). In contrast, SCL90-R scores did not differ significantly among the three groups. Euthymic bipolar patients experience subjective symptoms that are more confined to cognitive domain. This finding supports the hypothesis that subtle cognitive impairments persists in euthymic bipolar patients.

Posttraumatic Embitterment Disorder and Hwa-byung in the General Korean Population

Soohyun Joe,JungSun Lee,SeongYoon Kim,Seunghee Won,JongSeok Lim,KyooSeob Ha 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.4

Objective-Posttraumatic embitterment disorder (PTED) is characterized by states of “embitterment”, characteristically similar to “Hwa-byung”, which is a Korean culture-bound syndrome. The present study aimed to assess diagnostic relationships between PTED and Hwa-byung. Methods-A total of 290 participants completed our survey. PTED and Hwa-byung were diagnosed using a diagnostic interview and scale. Scales for depression, suicide ideation, and anger were used for evaluation. Fisher’s exact tests and Mann-Whitney U tests were performed to evaluate diagnostic overlap between PTED and Hwa-byung, and associations of scale scores for depression, suicide ideation, and anger between the PTED, Hwa-byung, and non-diagnosed groups. Associations of these scales between the depressive and non-depressive groups, and suicidal and non-suicidal groups were also evaluated. Results-Among the participants, 1.7% of the sample fit the diagnostic criteria for PTED and 2.1% fit the criteria for Hwa-byung. No individual fit the criteria for both. Anger scores were significantly higher in the Hwa-byung group than in the non-diagnostic group. There were not any significant differences in anger scores between the PTED and non-diagnostic groups. Depression scores were significantly higher in the PTED than in the non-diagnostic groups. In contrast, no significant differences were observed between depression scores in the Hwa-byung and non-diagnostic groups. Conclusion-These results suggest that PTED may be a disorder category that is distinct from Hwa-byung.

Prolonged Unmet Mental Health Needs of the 2017 Pohang Earthquake Survivors

Joe Soohyun,Lee Jungsun,Klaus Federica,Ng Hui Xin,Eyler Lisa T.,Lee Youngryeol 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.6

Objective Two years after the 2017 Pohang earthquake, some people sought follow-up mental health support. The demographic and clinical characteristics of this unique group of people were investigated to identify some insights on the predisposing factors of the longterm need for psychiatric help after a severe earthquake disaster.Methods De-identified data from those seeking mental health support 2 years after the 2017 Pohang earthquake were used. The descriptive statistics of demographic and clinical characteristics of the study group was identified and paired with general population data obtained from open and public governmental websites. Sex, age distribution, destruction of house, and psychiatric disorder were compared between the follow-up sample and general population.Results The proportion of women in the group seeking support was two times higher than that in the general population, and people ages between 50 and 70 years commonly sought support. The severity of home destruction was higher among people who sought and needed follow-up mental health support programs than in the general population. There was a higher proportion of people with psychiatric disorders in the group seeking support than in the general population.Conclusion The need for long-term mental health support 2 years after an earthquake was higher in women than in men and those aged between 50 and 70 years, and those with a previous psychiatric history and with a higher severity of home destruction, which lead to necessitating leaving the home. Future earthquake response should include screening and psychiatric treatment referral and residential support in vulnerable people.

Aziridine analogs of HIV NNRTI trovidine

Park KyungLae,Jung SangHun,Kim llWhan,Kim JinMyoung,Han SangSub,Joe SooHyun,Lee JeeHyun,Lee ChongKyo 大韓藥學會 2001 大韓藥學會 總會 및 學術大會 Vol.2001 No.2

유방암 환자에서 항암화학요법 후 인지기능과 후각기능의 변화 : 예비연구

임종석(Jongseok Lim),고수진(Su-Jin Koh),조수현(Soohyun Joe) 대한생물치료정신의학회 2017 생물치료정신의학 Vol.23 No.2

Objectives:This study evaluated olfactory identification performance and cognitive impairment following chemotherapy in patients with breast cancer. Methods:A total of 18 patients with breast cancer who were treated with chemotherapy were included in this study. The patients were evaluated for mental status, cognitive function, and olfactory identification performance before chemotherapy and 6 months after chemotherapy. Paired t-tests were used to examine the differences in scores before and after chemotherapy sessions. Results:No statistically significant differences were found in the scores of subjective cognitive function and olfactory identification performance pre- and post- chemotherapy. None of the objective cognitive function test scores declined at 6 months after chemotherapy. Mean scores of word list delayed recall(p=0.011), trail making A(p=0.026), symbol search(p=0.032), and modified Stroop test(p=0.002) showed significant improvement after chemotherapy. Among them, modified Stroop test score showed statistically significant improvement after Bonferroni correction. Conclusion:Olfactory and subjective cognitive functions of patients were not impaired 6 months after chemotherapy. However, some cognitive function related to execution improved 6 months after chemotherapy. These improvements in cognitive function after chemotherapy could be due to either a practice effect, recovery from acute stress due to cancer treatment, or an anti-inflammatory effect of chemotherapy. It is necessary to study the persistence of this pattern of cognitive improvement in long term follow-up.

메스암페타민 의존 환자에서 바이오피드백 훈련의 효과 : 정량화 뇌파를 이용한 예비연구

박창교(Changkyo Park),권도훈(Dohoon Kwon),조성남(Sungnam Cho),김양태(Yangtae Kim),김기성(Kiseong Kim),조수현(Soohyun Joe) 한국중독정신의학회 2012 중독정신의학 Vol.16 No.2

Objectives : In this study, authors investigated the neurophysiological effect of biofeedback training in patients with meth-amphetamine dependence using quantitative EEG (qEEG). Methods : Methamphetamine-dependent patients willing to receive biofeedback therapy were recruited in an addiction ward. qEEG measurements were conducted before and after each training session. Theta (4-8 Hz) relative power was measured and com-pared before and after biofeedback qEEG of each session. Results : A total of 49 pairs of relative power before and after bio-feedback qEEGs were obtained from 11 subjects with methamphetamine dependence. The right temporal theta relative power showed a significant decrease after biofeedback training. The right frontal theta relative power in the early biofeedback train-ing sessions showed a significant decrease compared with the later training sessions. Additionally, the right temporal theta relative power after the last-biofeedback training session also showed a significant decrease compared with the biofeedback before the first training session. Conclusion : These results suggested that the application of biofeedback training program changed brain waves and thus, could be a useful method of treat-ment for methamphetamine dependence.