2,5-Thienylene-Bridged Triangular and Linear Porphyrin Trimers

Song, Jianxin,Jang, So Young,Yamaguchi, Shigeru,Sankar, Jeyaraman,Hiroto, Satoru,Aratani, Naoki,Shin, Jae-Yoon,Easwaramoorthi, Shanmugam,Kim, Kil Suk,Kim, Dongho,Shinokubo, Hiroshi,Osuka, Atsuhiro WILEY-VCH Verlag 2008 Angewandte Chemie Vol.47 No.32

<B>Graphic Abstract</B> <P>A question of shape: Palladium-catalyzed cross-coupling of borylporphyrins has led to the synthesis of a β-to-β thienylene-bridged porphyrin dimer and two types of trimer (see picture; gray C; white H, pink Ni, yellow S, blue N). The ladderlike trimer exhibits a very large two-photon absorption cross-section (17 300 GM) at 800 nm, while that of the triangular trimer is moderate in comparison (8600 GM). <img src='wiley_img/14337851-2008-47-32-ANIE200802026-content.gif' alt='wiley_img/14337851-2008-47-32-ANIE200802026-content'> </P>

Directly Pd(II)-Bridged Porphyrin Belts with Remarkable Curvatures

Song, Jianxin,Aratani, Naoki,Heo, Ji Haeng,Kim, Dongho,Shinokubo, Hiroshi,Osuka, Atsuhiro American Chemical Society 2010 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.132 No.34

<P>A β,β′-doubly 2,6-pyridylene-bridged porphyrin dimer and trimer were prepared by Suzuki−Miyaura coupling reactions and confirmed to have largely bent structures. These oligoporphyrins were readily metalated via <I>meso</I>-C−H bond activation with the assistance of the pyridyl nitrogen atoms to produce the corresponding Pd(II) complexes, which display even larger bent structures and larger TPA values at 800 nm.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2010/jacsat.2010.132.issue-34/ja1046654/production/images/medium/ja-2010-046654_0004.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja1046654'>ACS Electronic Supporting Info</A></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja1046654'>ACS Electronic Supporting Info</A></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja1046654'>ACS Electronic Supporting Info</A></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja1046654'>ACS Electronic Supporting Info</A></P>

Porphyrin “Lego Block” Strategy To Construct Directly meso–β Doubly Linked Porphyrin Rings

Song, Jianxin,Aratani, Naoki,Kim, Pyosang,Kim, Dongho,Shinokubo, Hiroshi,Osuka, Atsuhiro WILEY-VCH Verlag 2010 Angewandte Chemie Vol.122 No.21

<B>Graphic Abstract</B> <P>Eingerastet: Die Suzuki-Miyaura-Kupplung von β,β′-diborylierten mit meso,meso′-dibromierten Porphyrinblöcken wird für den Aufbau direkt doppelt meso-β-verknüpfter Porphyrinringe genutzt, darunter zweier Tetraporphyrinringe, Hexaporphyrinringe und eines verbrückten Heptaporphyrins (siehe Bild). <img src='wiley_img_2010/00448249-2010-122-21-ANGE201000915-content.gif' alt='wiley_img_2010/00448249-2010-122-21-ANGE201000915-content'> </P>

Strategic Synthesis of 2,6-Pyridylene-Bridged β-to-β Porphyrin Nanorings through Cross-Coupling

Song, Jianxin,Kim, Pyosang,Aratani, Naoki,Kim, Dongho,Shinokubo, Hiroshi,Osuka, Atsuhiro WILEY-VCH Verlag 2010 Chemistry Vol.16 No.10

<B>Graphic Abstract</B> <P>The bridge determines the size of the loop? Palladium-catalyzed cross-coupling of borylporphyrins led to the construction of β-pyridine-bridged porphyrin nanorings in good yields (around 55–60 %; see scheme). The photophysical study revealed that these nanorings exhibit weakly coupled chromophores and longer fluorescent lifetimes, which is an apparent advantage in the process of efficient excited energy transfer. <img src='wiley_img_2010/09476539-2010-16-10-CHEM200903177-content.gif' alt='wiley_img_2010/09476539-2010-16-10-CHEM200903177-content'> </P>

Study of stability and evolution indexes of gobs under unloading effect in the deep mines

Fu, Jianxin,Song, Wei-Dong,Tan, Yu-Ye Techno-Press 2018 Geomechanics & engineering Vol.14 No.5

The stress path characteristics of surrounding rock in the formation of gob were analysed and the unloading was solved. Taking Chengchao Iron Mine as the engineering background, the model for analysing the instability of deep gob was established based on the mechanism of stress relief in deep mining. The energy evolution law was investigated by introducing the local energy release rate index (LERR), and the energy criterion of instability of surrounding rock was established based on the cusp catastrophe theory. The results showed that the evolution equation of the local energy release energy of the surrounding rock was quartic function with one unknown and the release rate increased gradually during the mining. The calculation results showed that the gob was stable. The LERR per unit volume of the bottom structure was relatively smaller, which mean the stability was better. The LERR distribution showed that there was main energy release in the horizontal direction and energy concentration in the vertical direction which meet the characteristics of deep mining. In summary, this model could effectively calculate the stability of surrounding rock in the formation of gob. The LERR could reflect the dynamic process of energy release, transfer and dissipation which provided an important reference for the study of the stability of deep mined out area.

Experimental study on unloading failure characteristics and damage evolution rules of deep diorite based on triaxial acoustic emission tests

Yang Li,Jianxin Fu,Nai Hao,Weidong Song,Ling Yu 한국지질과학협의회 2023 Geosciences Journal Vol.27 No.5

With the increasing depletion of shallow-earth mineral resources, deep mining will become the primary route of future mineral resources development. However, deep mining technology is a long way from being mature, and there are still a great number of issues that severely limit the growth of resources. In this paper, the acoustic emission (AE) tests of triaxially loaded and unloaded deep diorite are conducted. The results show that when confining pressure is at a low level, the failure mode of rock sample is mainly tension fracture; however as confining pressure increases, the failure mode gradually changes to shear failure. Under different stress paths, AE counting characteristics can be separated into four stages, including initial low-energy zone, pre-peak quiet zone, peak sudden burst zone and post-peak failure intensive zone (post-peak fast attenuation zone or post-peak high density zone). The damage variable is defined as the ratio of the AE count rate of a certain stage to the cumulative AE count rate of the failure process, and it accounts for the largest proportion at the stage of unloading confining pressure. In addition, when confining pressure increases, thedamage variable changes from a flat growth to a rapid growth, with the abrupt transition occurring around the peak stress.

Effect of digestion product of royal jelly protein on SGC-7901 gastric cancer cell

Fu Li,Wang Tianshi,Song Jianxin 한국응용곤충학회 2024 Journal of Asia-Pacific Entomology Vol.27 No.1

Royal jelly used for larvae and queens has many health-promoting properties such as spatial memory improvement, antibacterial activity and antioxidant capacity. However, the anticancer ability of the royal jelly is not unknown. In this study, effect of the royal jelly protein on SGC-7901 gastric cancer cell was investigated, and the key factors including the cell morphological, the colony formation, the proliferation, the cycle, and the expression of p53 and poly (ADP-ribose) polymerase-1 (PARP-1) proteins were analyzed. Result showed royal jelly protein was excellent in inhibiting the growth of SGC-7901gastric cancer cell. After treating with the digestion product of royal jelly protein (0.05 mg/mL~0.20 mg/mL), the morphological of gastric cancer cell significantly shrink, and both of density and quantity (1000~491) of gastric cancer cell significantly (p < 0.05) decreased. The proliferation of gastric cancer was strongest inhibited by 62.84 % of 0.20 mg/mL royal jelly protein. The expression of p53 and PARP-1 protein of gastric cancer cell was respectively enhanced (0.29~0.46) and reduced (0.51~0.42). Moreover, the higher content of royal jelly protein (0.05 mg/mL~ 0.2 mg/mL), the stronger inhibit ability of 45 SGC-7901 gastric cancer cell. In conclusion, royal jelly protein can be used as a potential food in adjunctive therapy for gastric cancer.

Effect of digestion product of royal jelly protein on SGC-7901 gastric cancer cell

Fu Li,Wang Tianshi,Song Jianxin 한국응용곤충학회 2024 Journal of Asia-Pacific Entomology Vol.27 No.1

Royal jelly used for larvae and queens has many health-promoting properties such as spatial memory improvement, antibacterial activity and antioxidant capacity. However, the anticancer ability of the royal jelly is not unknown. In this study, effect of the royal jelly protein on SGC-7901 gastric cancer cell was investigated, and the key factors including the cell morphological, the colony formation, the proliferation, the cycle, and the expression of p53 and poly (ADP-ribose) polymerase-1 (PARP-1) proteins were analyzed. Result showed royal jelly protein was excellent in inhibiting the growth of SGC-7901gastric cancer cell. After treating with the digestion product of royal jelly protein (0.05 mg/mL~0.20 mg/mL), the morphological of gastric cancer cell significantly shrink, and both of density and quantity (1000~491) of gastric cancer cell significantly (p < 0.05) decreased. The proliferation of gastric cancer was strongest inhibited by 62.84 % of 0.20 mg/mL royal jelly protein. The expression of p53 and PARP-1 protein of gastric cancer cell was respectively enhanced (0.29~0.46) and reduced (0.51~0.42). Moreover, the higher content of royal jelly protein (0.05 mg/mL~ 0.2 mg/mL), the stronger inhibit ability of 45 SGC-7901 gastric cancer cell. In conclusion, royal jelly protein can be used as a potential food in adjunctive therapy for gastric cancer.

Optimization of medium components for D-ribose production by transketolase-deficient Bacillus subtilis NJT-1507

Hanjie Ying,Ting Fang,Xiaochun Chen,Nan Li,He Song,Jianxin Bai,Jian Xiong 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.6

Statistical experimental designs were used to optimize the composition of culture media for the production of D-ribose by Bacillus subtilis. A fractional factorial design 2(5-2) was used to determine medium components that significantly affected D-ribose production. The concentrations of glucose and (NH4)2SO4 were the significant factors. Central composite design and response surface methodology were then used to estimate the quadratic response surface and determine the factor levels for maximum production of D-ribose. Finally, the optimal medium composition was obtained (g/L): glucose, 172.75; (NH4) 2SO4, 13.2; yeast powder, 4; corn steep liquor, 8 and MnSO4, 0.5. This optimization strategy increased D-ribose production from 73.21 g/L to 88.57 g/L, an increase of 22% compared with the original conditions. The D-ribose production yield to glucose concentration was also enhanced from 0.37 g/g to 0.52 g/g. Confirmatory experiments were also performed to demonstrate the accuracy of the model. Under the optimal medium using ammonia to control pH in a 5 L fermenter, the D-ribose yield was increased to 95.28 g/L after 3 days of cultivation at 37 oC.

Porphyrin–Azobenzene–Bodipy Triads: Syntheses, Structures, and Photophysical Properties

Yin, Bangshao,Kim, Taeyeon,Zhou, Mingbo,Huang, Weiming,Kim, Dongho,Song, Jianxin American Chemical Society 2017 Organic letters Vol.19 No.10

<P>Cyclic and acyclic azobenzene bridged porphyrin-dipyrrin derivatives were successfully prepared via Suzuki- Miyaura coupling reaction of alpha,alpha'-diborylated dipyrromethane with bromoazophenyl porphyrin or reaction of borylated porphyrin with dibromoazophenyl dipyrrin, and the corresponding porphyrin Bodipy derivatives were obtained by subsequent boron complexation. The cyclic porphyrin dipyrrin compound 3Ni was confirmed by X-ray diffraction. The low fluorescence quantum yields of azobenzene bridged porphyrin Bodipy can be ascribed to the presence of the intramolecular charge transfer state.</P>